Click here to switch to the map view.

The map label for this gene is yngJ [H]

Identifier: 126173735

GI number: 126173735

Start: 1741105

End: 1742262

Strand: Direct

Name: yngJ [H]

Synonym: Sbal_1497

Alternate gene names: 126173735

Gene position: 1741105-1742262 (Clockwise)

Preceding gene: 126173734

Following gene: 126173736

Centisome position: 33.96

GC content: 51.99

Gene sequence:

>1158_bases
ATGGATTTTAATTTCAACGATGACCAACGCCAGTTTGCCGATCTTGCGCGCCAGTTTGCCGCGGAAGAGTTAACCCCGTT
TGCCGCCAAGTGGGATGAAGAACATCATTTCCCCAAAGACGTGATCCAAAAAGCCGGTGAGCTGGGTTTTTGCTCTTTGT
ATTCGCCCGAATCTGAAGGTGGCATGGGCTTATCGCGCCTCGATGCGTCGATTATTTTTGAAGAGCTCGCCAAGGGTTGT
ACAGCGACCACGGCCATGCTGACCATTCACAATATGGCCACTTGGATGGTGACGACTTGGGGAACTGAAACCCTGCGTCA
GACTTGGTCTGAGCCGTTAACCACAGGGCAAATGTTAGCGTCCTATTGTTTAACTGAGCCGGGTGCGGGTTCAGACGCCG
CATCTTTGCAAACCAAAGCGGTGCGTGACGGTGATGAGTATGTGATTTCAGGTTCGAAAATGTTTATCTCAGGTGCGGGC
GCCACTGAGCTATTAGTGGTGATGTGCCGCACGGGTCAAGCTGGGCCTAAGGGGATTTCGGCCATTGCCATTCCGGCGGA
TGCCGCTGGCGTTATCTACGGTAAGGCCGAAGATAAAATGGGCTGGAATGCCCAGCCGACCCGCCAAATCACCTTCGAAA
ATGTGCGCGTGCCAGTAGCGAATTTGCTCGGTGAAGAAGGCCAAGGTTTTGCCTTCGCGATGAAAGGCTTAGACGGTGGT
CGTATCAATATTGCGACCTGTTCAGTCGGTACGGCGCAAGCGGCGCTGGAGCGTGCAACTCAGTATATGAATGAGCGTCA
GCAATTTGGTAAACCGTTAGCGGCGTTCCAGGCATTGCAATTTAAACTCGCCGATATGGCGACTGAGTTAGTCGCAGCCC
GCCAAATGGTGCGCCTTGCGGCCTTTAAACTCGATAGTCATGATCCTGAAGCCACTGCCTATTGCGCCATGGCGAAACGT
TTTGCCACCGATGTGGGCTTTCAAGTCTGTGATGCGGCGCTGCAAATTCATGGCGGATATGGTTATATAAGGGAGTACCC
GCTGGAACGTCATTTCCGTGATGTGCGTGTGCACCAGATTTTAGAAGGCACCAACGAAATTATGCGCTTAATTATCGCCC
GTCGTTTACTCGATGAAAATGCAGGACAAATCCTCTAA

Upstream 100 bases:

>100_bases
CTCGTACGTCAAGCTCGGTGATTAATCGATAAACTGTGGCGTCTTTACGGCGCCTAATTTATTAAATAAAAAAGTGACCA
CAGAGTCATAGGAGAGCCAA

Downstream 100 bases:

>100_bases
GTCCACTCGCAAGAAGTGTGACTTATCGGTTGGCGATAACATAAAAGGAGTCTATACAGATGGAATATTTAGTAGAACGT
ATCGAAGGCCATACGGCCAT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MDFNFNDDQRQFADLARQFAAEELTPFAAKWDEEHHFPKDVIQKAGELGFCSLYSPESEGGMGLSRLDASIIFEELAKGC
TATTAMLTIHNMATWMVTTWGTETLRQTWSEPLTTGQMLASYCLTEPGAGSDAASLQTKAVRDGDEYVISGSKMFISGAG
ATELLVVMCRTGQAGPKGISAIAIPADAAGVIYGKAEDKMGWNAQPTRQITFENVRVPVANLLGEEGQGFAFAMKGLDGG
RINIATCSVGTAQAALERATQYMNERQQFGKPLAAFQALQFKLADMATELVAARQMVRLAAFKLDSHDPEATAYCAMAKR
FATDVGFQVCDAALQIHGGYGYIREYPLERHFRDVRVHQILEGTNEIMRLIIARRLLDENAGQIL

Sequences:

>Translated_385_residues
MDFNFNDDQRQFADLARQFAAEELTPFAAKWDEEHHFPKDVIQKAGELGFCSLYSPESEGGMGLSRLDASIIFEELAKGC
TATTAMLTIHNMATWMVTTWGTETLRQTWSEPLTTGQMLASYCLTEPGAGSDAASLQTKAVRDGDEYVISGSKMFISGAG
ATELLVVMCRTGQAGPKGISAIAIPADAAGVIYGKAEDKMGWNAQPTRQITFENVRVPVANLLGEEGQGFAFAMKGLDGG
RINIATCSVGTAQAALERATQYMNERQQFGKPLAAFQALQFKLADMATELVAARQMVRLAAFKLDSHDPEATAYCAMAKR
FATDVGFQVCDAALQIHGGYGYIREYPLERHFRDVRVHQILEGTNEIMRLIIARRLLDENAGQIL
>Mature_385_residues
MDFNFNDDQRQFADLARQFAAEELTPFAAKWDEEHHFPKDVIQKAGELGFCSLYSPESEGGMGLSRLDASIIFEELAKGC
TATTAMLTIHNMATWMVTTWGTETLRQTWSEPLTTGQMLASYCLTEPGAGSDAASLQTKAVRDGDEYVISGSKMFISGAG
ATELLVVMCRTGQAGPKGISAIAIPADAAGVIYGKAEDKMGWNAQPTRQITFENVRVPVANLLGEEGQGFAFAMKGLDGG
RINIATCSVGTAQAALERATQYMNERQQFGKPLAAFQALQFKLADMATELVAARQMVRLAAFKLDSHDPEATAYCAMAKR
FATDVGFQVCDAALQIHGGYGYIREYPLERHFRDVRVHQILEGTNEIMRLIIARRLLDENAGQIL

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=55.4666666666667, Blast_Score=446, Evalue=1e-125,
Organism=Homo sapiens, GI4557231, Length=381, Percent_Identity=39.1076115485564, Blast_Score=278, Evalue=6e-75,
Organism=Homo sapiens, GI187960098, Length=381, Percent_Identity=39.1076115485564, Blast_Score=278, Evalue=7e-75,
Organism=Homo sapiens, GI4557233, Length=363, Percent_Identity=41.5977961432507, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=36.8983957219251, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI21361497, Length=387, Percent_Identity=34.8837209302326, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=32.8042328042328, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=30.8510638297872, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI76496475, Length=387, Percent_Identity=32.2997416020672, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI4557235, Length=387, Percent_Identity=32.2997416020672, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=31.547619047619, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI38505218, Length=372, Percent_Identity=29.8387096774194, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=26.984126984127, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI48976061, Length=369, Percent_Identity=28.4552845528455, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI211971008, Length=369, Percent_Identity=28.4552845528455, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI7669494, Length=355, Percent_Identity=26.7605633802817, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=30.7086614173228, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI87081958, Length=389, Percent_Identity=31.6195372750643, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI87082384, Length=304, Percent_Identity=27.3026315789474, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=51.7333333333333, Blast_Score=406, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=39.9477806788512, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=37.5328083989501, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=37.434554973822, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=36.4864864864865, Blast_Score=233, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=33.7765957446808, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=32.4607329842932, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=31.2335958005249, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17505929, Length=358, Percent_Identity=31.8435754189944, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI71990804, Length=285, Percent_Identity=35.7894736842105, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17551932, Length=363, Percent_Identity=31.404958677686, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=39.6551724137931, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17534353, Length=381, Percent_Identity=27.5590551181102, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=28.3636363636364, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=328, Percent_Identity=29.8780487804878, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17562446, Length=363, Percent_Identity=29.7520661157025, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=28.9795918367347, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17531913, Length=188, Percent_Identity=28.1914893617021, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=306, Percent_Identity=26.1437908496732, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=306, Percent_Identity=26.1437908496732, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=38.7012987012987, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=40.3269754768392, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24646207, Length=364, Percent_Identity=40.1098901098901, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=34.9462365591398, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=33.1592689295039, Blast_Score=207, Evalue=7e-54,
Organism=Drosophila melanogaster, GI281363737, Length=341, Percent_Identity=35.1906158357771, Blast_Score=204, Evalue=7e-53,
Organism=Drosophila melanogaster, GI19920834, Length=383, Percent_Identity=27.9373368146214, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42063; Mature: 42063

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFNFNDDQRQFADLARQFAAEELTPFAAKWDEEHHFPKDVIQKAGELGFCSLYSPESEG
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHCCCCCEEEECCCCCCC
GMGLSRLDASIIFEELAKGCTATTAMLTIHNMATWMVTTWGTETLRQTWSEPLTTGQMLA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCCHHHHHHH
SYCLTEPGAGSDAASLQTKAVRDGDEYVISGSKMFISGAGATELLVVMCRTGQAGPKGIS
HHHHCCCCCCCCHHHHHHHHHCCCCCEEEECCEEEEECCCHHHHHHHHCCCCCCCCCCCE
AIAIPADAAGVIYGKAEDKMGWNAQPTRQITFENVRVPVANLLGEEGQGFAFAMKGLDGG
EEEECCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCEEEEEECCCCC
RINIATCSVGTAQAALERATQYMNERQQFGKPLAAFQALQFKLADMATELVAARQMVRLA
EEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFKLDSHDPEATAYCAMAKRFATDVGFQVCDAALQIHGGYGYIREYPLERHFRDVRVHQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHCCCHHHHHHHHHHHHH
LEGTNEIMRLIIARRLLDENAGQIL
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDFNFNDDQRQFADLARQFAAEELTPFAAKWDEEHHFPKDVIQKAGELGFCSLYSPESEG
CCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHCCCCCEEEECCCCCCC
GMGLSRLDASIIFEELAKGCTATTAMLTIHNMATWMVTTWGTETLRQTWSEPLTTGQMLA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCHHHHHHHHHCCCHHHHHHH
SYCLTEPGAGSDAASLQTKAVRDGDEYVISGSKMFISGAGATELLVVMCRTGQAGPKGIS
HHHHCCCCCCCCHHHHHHHHHCCCCCEEEECCEEEEECCCHHHHHHHHCCCCCCCCCCCE
AIAIPADAAGVIYGKAEDKMGWNAQPTRQITFENVRVPVANLLGEEGQGFAFAMKGLDGG
EEEECCCCCEEEEECCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCEEEEEECCCCC
RINIATCSVGTAQAALERATQYMNERQQFGKPLAAFQALQFKLADMATELVAARQMVRLA
EEEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFKLDSHDPEATAYCAMAKRFATDVGFQVCDAALQIHGGYGYIREYPLERHFRDVRVHQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHCCCHHHHHHHHHHHHH
LEGTNEIMRLIIARRLLDENAGQIL
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]