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The map label for this gene is yeiR [H]

Identifier: 126173576

GI number: 126173576

Start: 1532943

End: 1534070

Strand: Direct

Name: yeiR [H]

Synonym: Sbal_1338

Alternate gene names: 126173576

Gene position: 1532943-1534070 (Clockwise)

Preceding gene: 126173575

Following gene: 126173578

Centisome position: 29.9

GC content: 46.45

Gene sequence:

>1128_bases
ATGATTATCAAAGCGATTCCCACCAATATCATCACAGGTTTTTTAGGCGTAGGTAAAACCTCTCTGATTAAACAATTGCT
GGCGACTAAACCCGCGGATGAGACTTGGGCAGTGCTGGTCAATGAGTTTGGTGAGGTTGGCATTGATGCGGGGTTACTGA
ATTCTTCCGATAACGGCATACAAATTCGTGAGGTGGCGGGTGGCTGTATGTGCTGCGCCGCGGGCGTGCCGACGCAAGTG
GCGATCAATCAGTTGATTGCGAAAGCAAAACCTGATCGCTTATTGATTGAACCGACTGGGCTTGGGCATCCTAATGAAAT
CATTAAAGTATTGAGTGCACCCCATTATCAGAATGTGATTTCACTGCGCAGTACTTTATGTTTGGTGGACGCGCGTAAAA
TCCACGATCCCCGCTATCGCGAACATGCAAACTTCATCCAACAGCTGCAAGTGGCCGATGTGATTATCGCGACTAAGTCG
GATTTATATGATGCTGAAAATACTAAGTTACTCTATGAGTTACAGACCTATTTAAGTCATATCGAACGTACTGATATTCC
TGTGGTGAGCCACACTAACCAGCAACCTTTACCTAGCGCGCTGCTGAATTATTTAAACCAACCAAGGCGCGTGTCACTCA
ACATTAGCAGTAATGGTGGCATAGTCCCTAAACTAGGTAATCTTACAACGACAGCGCCAAGCCTGTTCCGCACGGGTGGT
TCGCGTTTGAGTGAGTTAAGCCTTTTTGCCGAAGGCGCAATCGAAGTCGCACTCGAATTTGATGCACGTGGCATAGTGCG
CAAGCAGAATCAAGGCGAAGGCTGTTTTAGCTGCGGCTGGGTGTTTGAACCAAGACAAGAGTTTGATTTCGATAAATTAA
TGGCGTTTATTCAGCGTTACACTCAGTCATCAGACGTCGGGCAAGTCTTGCTGAGGTTAAAGGCTGTAATGATCACCTCT
GAGGGGATCGCTGGATTTAACTGGATTGATCATGAGTTTACTGTGGTTGAACTCGATGACACCTTAGATTCCAGACTTGA
GATGATTACAGTGAATGACGTCGATTGGGATGAGATAGAGCAGCAGTTGCTCGCCTGTCTTTGTTCACTGTGCTCTTCTA
ACGGTTAA

Upstream 100 bases:

>100_bases
CATTCTAAAAGCGCATCCTCACCGATGCGCTTTTTGTTGAGCTTCAAAGCCAATACTTCTACACTCGAGCGCCAAGCTTT
CTATTCGAGCGAGTTTCCTT

Downstream 100 bases:

>100_bases
CTGGCTTTCCCGTCGCCCTTTATCACACATGTGATCATAGGTCAGGCGGGTGCTAATAAAGTTGAAGCGGTCGTACATGA
AGGAGCAGTCGTGCATGATC

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MIIKAIPTNIITGFLGVGKTSLIKQLLATKPADETWAVLVNEFGEVGIDAGLLNSSDNGIQIREVAGGCMCCAAGVPTQV
AINQLIAKAKPDRLLIEPTGLGHPNEIIKVLSAPHYQNVISLRSTLCLVDARKIHDPRYREHANFIQQLQVADVIIATKS
DLYDAENTKLLYELQTYLSHIERTDIPVVSHTNQQPLPSALLNYLNQPRRVSLNISSNGGIVPKLGNLTTTAPSLFRTGG
SRLSELSLFAEGAIEVALEFDARGIVRKQNQGEGCFSCGWVFEPRQEFDFDKLMAFIQRYTQSSDVGQVLLRLKAVMITS
EGIAGFNWIDHEFTVVELDDTLDSRLEMITVNDVDWDEIEQQLLACLCSLCSSNG

Sequences:

>Translated_375_residues
MIIKAIPTNIITGFLGVGKTSLIKQLLATKPADETWAVLVNEFGEVGIDAGLLNSSDNGIQIREVAGGCMCCAAGVPTQV
AINQLIAKAKPDRLLIEPTGLGHPNEIIKVLSAPHYQNVISLRSTLCLVDARKIHDPRYREHANFIQQLQVADVIIATKS
DLYDAENTKLLYELQTYLSHIERTDIPVVSHTNQQPLPSALLNYLNQPRRVSLNISSNGGIVPKLGNLTTTAPSLFRTGG
SRLSELSLFAEGAIEVALEFDARGIVRKQNQGEGCFSCGWVFEPRQEFDFDKLMAFIQRYTQSSDVGQVLLRLKAVMITS
EGIAGFNWIDHEFTVVELDDTLDSRLEMITVNDVDWDEIEQQLLACLCSLCSSNG
>Mature_375_residues
MIIKAIPTNIITGFLGVGKTSLIKQLLATKPADETWAVLVNEFGEVGIDAGLLNSSDNGIQIREVAGGCMCCAAGVPTQV
AINQLIAKAKPDRLLIEPTGLGHPNEIIKVLSAPHYQNVISLRSTLCLVDARKIHDPRYREHANFIQQLQVADVIIATKS
DLYDAENTKLLYELQTYLSHIERTDIPVVSHTNQQPLPSALLNYLNQPRRVSLNISSNGGIVPKLGNLTTTAPSLFRTGG
SRLSELSLFAEGAIEVALEFDARGIVRKQNQGEGCFSCGWVFEPRQEFDFDKLMAFIQRYTQSSDVGQVLLRLKAVMITS
EGIAGFNWIDHEFTVVELDDTLDSRLEMITVNDVDWDEIEQQLLACLCSLCSSNG

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=176, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI223941779, Length=176, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI33469141, Length=176, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI148727351, Length=176, Percent_Identity=31.25, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1788499, Length=358, Percent_Identity=36.3128491620112, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI87082430, Length=168, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=113, Percent_Identity=34.5132743362832, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 41255; Mature: 41255

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKAIPTNIITGFLGVGKTSLIKQLLATKPADETWAVLVNEFGEVGIDAGLLNSSDNGI
CEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCE
QIREVAGGCMCCAAGVPTQVAINQLIAKAKPDRLLIEPTGLGHPNEIIKVLSAPHYQNVI
EEEECCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHH
SLRSTLCLVDARKIHDPRYREHANFIQQLQVADVIIATKSDLYDAENTKLLYELQTYLSH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHH
IERTDIPVVSHTNQQPLPSALLNYLNQPRRVSLNISSNGGIVPKLGNLTTTAPSLFRTGG
HHHCCCCEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHCCC
SRLSELSLFAEGAIEVALEFDARGIVRKQNQGEGCFSCGWVFEPRQEFDFDKLMAFIQRY
HHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCCCEEECCEECCHHHCCHHHHHHHHHHH
TQSSDVGQVLLRLKAVMITSEGIAGFNWIDHEFTVVELDDTLDSRLEMITVNDVDWDEIE
HCCCHHHHHHHHHHHHHEECCCCCCCEEECCEEEEEEECCCCCCCEEEEEECCCCHHHHH
QQLLACLCSLCSSNG
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MIIKAIPTNIITGFLGVGKTSLIKQLLATKPADETWAVLVNEFGEVGIDAGLLNSSDNGI
CEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCE
QIREVAGGCMCCAAGVPTQVAINQLIAKAKPDRLLIEPTGLGHPNEIIKVLSAPHYQNVI
EEEECCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHH
SLRSTLCLVDARKIHDPRYREHANFIQQLQVADVIIATKSDLYDAENTKLLYELQTYLSH
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHH
IERTDIPVVSHTNQQPLPSALLNYLNQPRRVSLNISSNGGIVPKLGNLTTTAPSLFRTGG
HHHCCCCEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHCCC
SRLSELSLFAEGAIEVALEFDARGIVRKQNQGEGCFSCGWVFEPRQEFDFDKLMAFIQRY
HHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCCCEEECCEECCHHHCCHHHHHHHHHHH
TQSSDVGQVLLRLKAVMITSEGIAGFNWIDHEFTVVELDDTLDSRLEMITVNDVDWDEIE
HCCCHHHHHHHHHHHHHEECCCCCCCEEECCEEEEEEECCCCCCCEEEEEECCCCHHHHH
QQLLACLCSLCSSNG
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]