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The map label for this gene is aer [H]

Identifier: 126173476

GI number: 126173476

Start: 1424196

End: 1425764

Strand: Direct

Name: aer [H]

Synonym: Sbal_1238

Alternate gene names: 126173476

Gene position: 1424196-1425764 (Clockwise)

Preceding gene: 126173470

Following gene: 126173477

Centisome position: 27.78

GC content: 49.46

Gene sequence:

>1569_bases
ATGCATAAAAATTCTAAGAATGGTGAAACACACCTGTCAGATAATGCGATTCTACTATCCACAACGGATTTGAAGGGAAA
CATTAAATATGTGAATCAGACTTTTTCGCAGATCAGCGAGTTTAGCGCCGCTGAGTTGCAAGGGAATCCCCATAACATAG
TGCGTCATCAAGATATGCCAGCGGCTGCGTTTAAGATCCTTTGGGAGCGAATTAAGCAGGGTAAACCTTGGATGGGGATC
GTTAAAAATCGCACTAAAAATGGCGGTTATTACTGGGTAAATGCCTATGTCGCCCCTGTGTATGAAGACGGTAAAATTCA
CGAATATCAATCTGTTCGCCGCCAAGCCACTCCAGAGCAGATCAAAGCCGCCGAGAGTATTTACAGCGATATTAATCAGG
GTAAGCAACCTAAGGTATTGCGCAAAGACAGGTTAGGTTTCAGTGGCAAGATACTGCTGGCCATGCTGATGTCGATTATG
ACTACGACAATAATTGCCAGTTATTCTCCCATTGTTGCTGCGATTGCGGGGATGACGGTAGCGTGCCTAGCATGGTATTA
CCTGATGCAGCCGCTGCAAAAGCTCGTTTCTATGGCGACCAACATTATTGACGATCCTGTGGCGACGGGCGTGTACACCG
GCCGCCAGGATGAGATTGGAAAATTGGATCTCGCCCTGCGCTTTTTGATCACCGAAATCGGTGGCGTTGTCGGCCGTATG
GCGGATTCGGCCAGTGAAATACAATCTCAGAGTGTGAGCCTTAAACAAACCATTACCAACACTTGGGAACATGCCGATAG
TCAGAGCGAACAAACAACGCAGGCCGCGACGGCGATGGAGCAGATGAGCGCCAGTTTTGCCGAAGTGACGGGCAACATTC
ATCGTACTGCCTCTGAAATGGTGTCGAGCCATGAGGCGGCGCAACGCGGGCATTCACGTTTAGAAACAGTGATAGAGGCG
ATACATCAGTTGAGTGTGCAAGTGAGCCACTTTTCCGATGTGGTTCAAACGATTGAAGAAGATAGCCGTGCGATTCATCA
AGTGCTTGAAGTGATACGTGCCATCGCTGACCAAACCAACTTGTTAGCTTTAAATGCGGCAATCGAAGCGGCGCGGGCAG
GGGATAGTGGTCGCGGTTTTGCAGTGGTGGCCGATGAGGTCAGACAATTATCGAGTCGTACTAGCCAATCCACCTCGCAA
ATCGAGTTAATCGTTAGCCGCTTTAGGGAAAGTACCCAAAGGGCGACTTCGACTATGGTGGCGGGACAAGAGCAGGTTAA
ACGTTCGGTAGGCTTAGCGCAGGAAGCCAGTGTCGCTTTTGGCGAGCTGCTTTCATCCATAACAAGGATTAACTCCTTAA
GTGATGATAATGCCGCGGCGATGACCCAGCAGACTTCTGTGGCCGCTGAAATTAGCCGTGCCATCCATGTGATCAGCGAT
TTGGCTCAACAGAGTTTAGAGCAGACGCTCGATGCGGCGGCGCGGGGCGATCAAGTGTCGCGTTTATCGACCAAGACTCA
TCATCTGTCCCAACAGTTTTGGCAGCAGAGTGTGCAACGTAAATATTAA

Upstream 100 bases:

>100_bases
AATTTTTGTGCTGCCAATGTGAGCTTTATCAATTTTGATGTACTGAGGTTTTGGCAGAATGCTCGTTATCTTTTTTACCG
AGACCTAGCCTGATAACCCT

Downstream 100 bases:

>100_bases
GCGTTTTTACCTTATGTCGTATTGGATTTTGTGATTGATTTATTATTAATGCCTGTTTATAAATCAATCACTTAATTGCA
TTTTTCTGGCGGTTTTATTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMPAAAFKILWERIKQGKPWMGI
VKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQIKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIM
TTTIIASYSPIVAAIAGMTVACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFRESTQRATSTMVAGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Sequences:

>Translated_522_residues
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMPAAAFKILWERIKQGKPWMGI
VKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQIKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIM
TTTIIASYSPIVAAIAGMTVACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFRESTQRATSTMVAGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
>Mature_522_residues
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMPAAAFKILWERIKQGKPWMGI
VKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQIKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIM
TTTIIASYSPIVAAIAGMTVACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEMVSSHEAAQRGHSRLETVIEA
IHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTNLLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQ
IELIVSRFRESTQRATSTMVAGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=502, Percent_Identity=31.0756972111554, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI2367378, Length=332, Percent_Identity=27.1084337349398, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=344, Percent_Identity=29.3604651162791, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787690, Length=410, Percent_Identity=28.5365853658537, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=25.5737704918033, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57350; Mature: 57350

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMP
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
AAAFKILWERIKQGKPWMGIVKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQ
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHCCHHH
IKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIMTTTIIASYSPIVAAIAGMTV
HHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSHEAAQRGHSRLETVIEAIHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQIELIVSRFRESTQRATSTMV
EEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKNSKNGETHLSDNAILLSTTDLKGNIKYVNQTFSQISEFSAAELQGNPHNIVRHQDMP
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCC
AAAFKILWERIKQGKPWMGIVKNRTKNGGYYWVNAYVAPVYEDGKIHEYQSVRRQATPEQ
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHCCHHH
IKAAESIYSDINQGKQPKVLRKDRLGFSGKILLAMLMSIMTTTIIASYSPIVAAIAGMTV
HHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ACLAWYYLMQPLQKLVSMATNIIDDPVATGVYTGRQDEIGKLDLALRFLITEIGGVVGRM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ADSASEIQSQSVSLKQTITNTWEHADSQSEQTTQAATAMEQMSASFAEVTGNIHRTASEM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSHEAAQRGHSRLETVIEAIHQLSVQVSHFSDVVQTIEEDSRAIHQVLEVIRAIADQTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLALNAAIEAARAGDSGRGFAVVADEVRQLSSRTSQSTSQIELIVSRFRESTQRATSTMV
EEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQEQVKRSVGLAQEASVAFGELLSSITRINSLSDDNAAAMTQQTSVAAEISRAIHVISD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LAQQSLEQTLDAAARGDQVSRLSTKTHHLSQQFWQQSVQRKY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]