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The map label for this gene is ptsP [H]

Identifier: 126173423

GI number: 126173423

Start: 1367685

End: 1369919

Strand: Direct

Name: ptsP [H]

Synonym: Sbal_1185

Alternate gene names: 126173423

Gene position: 1367685-1369919 (Clockwise)

Preceding gene: 126173422

Following gene: 126173424

Centisome position: 26.67

GC content: 48.99

Gene sequence:

>2235_bases
GTGTTAAATACGCTTAGGGATATTACTCAGGCTGTGGCATCTGCCCACAGTTTGGAAACCGCATTAGAAGTCTTAGTCTC
ATCGACTAAAGCGGCGATGGAAACCCAATGTTGCTCCATCTATATCCTAGAAGAGCAAGAACTGGTGTTATCTGCAACCG
ACGGTCTTGAAAAAAGCGCCGTTGGTCGGGTACGTATGCCGCTGACCGAAGGTTTAGTTGGACTCGCAGCCCAGCGGGAA
GAGGCTGTTAACTTAGCGGATGCACGGCTTCATCCTCGATTCAAACTTTTCCCTGAAGTCGCCGAAGAAGAATACCGCGC
CTTTTTAGCTGTACCTATCATCTACCAGAAAGCAGTGGTCGGGGTGATAGTGGTTCAGCAGGCGAGTGCGCGCCAATTCA
GTGAAGGCGAAGAAGCCTTCCTGATGACGCTCGCCGCCCAGTTAGCAATGGCGGTGCGCGGCTTAAAACAAAAAGCCCAA
GTCAGTTCCCATCATCAACAAATTCTATTTCAAGGTACGTCGGCATCAAACGGTATCGCCATTGCGTATGCCTTTGTGCT
CGGTGGAGAGATCCCCCTTGAGCAGCCCGATATGCACTCTGACGACATTGTCTATGAGTCGAGCCGCTTAACGACGGCTA
TGGTGCGTTGTAAAGAAGCGATTGGCGCTTTATCTCAGCGGTTTGATCGCGAGCAAGATGACGAAGTTGTCTCTATTTTC
AATGCATTACAGCTATTACTTGATGGTGCCAGTTTAGGCGGAGAGTATGCCCGCGAGGTGCAATTAGGTTGGGCTGCTGA
ATCGGCGGTAAGCCGAGTGTCCTTGCGTTATATTCAGCAATTTTTGGCCATGGAAGATCCTTATCTTAAGGAGCGGGCAA
GCGATATCCGCGACTTAGGTCAAAAAGTATTGCGCCAGTTGATTGAGCCAGAGCGTTTAGAGCTTGAACCCGATAAACCT
GTCATTTTAATTACCCGCGAAGCCGATGCGACTATGCTGGCTGAGTTCCCAAGGCAGAAACTTGCGGGGATTGTCACTGA
GCTTGGCGGCGTAAACTCCCATGCCGCTATTTTAGCCCGCGCCTTAGGTGTGCCGGCCATTACCGGTGTAGAACAACTAT
TATCCGCCAATATTGATCAAAAACTCTTAGTGGTGAACGCCAGCCGTGGCCAGCTATTGGTGTCGCCATCACCGGCGATT
GTTGGTGAGTATCGCAGCTTAATTTCGGCGCAAAAAGCGCTGCAACGCCAGTATGCTCAAGAATTAGCACTGCCTTCTGT
TACCTTAGATGGCTCACGTATTCGTTTGTATTTAAATGCGGGATTACTCAGCGGCGTGGCTTCTGAAATTGCCGAAGGTG
CCGACGGGATTGGGCTGTATCGCACCGAAATCCCTTTTATGCTGCAACAACGTTTCCCGAGTGAATCTGAGCAAGTGAAA
GTGTATCAACAGGTCTTGTCGGCGGCGTCTGGTCGACCTGTGGTGATGCGCACTTTGGATGTTGGCGGCGATAAACCTCT
GCCGTATTTCCCAATTAAAGAAGATAATCCTTTCCTTGGTTGGCGCGGGATCCGTTTGTCGCTGGATCATCCAGAATTAT
TTTTGGTGCAGTTACGGGCCATGTTGCAGGCAGGAGGTGACGGTAAACAGCTGAGTATTTTACTGCCCATGGTCAGTAAC
TTAGATGAAATCGATCAATCCTTAGAATATCTGCAGCAAGCCTATGTCGAACTTAAAAACGATGTAAACAGCAACATAGT
GATGCCACGCATCGGCATTATGCTCGAAGTGCCGGCTATGTTGTATCAATTGGATGATGTGGCAAAACGGGTGGATTTTG
TCTCCGTTGGCAGTAATGACTTAACCCAGTATTTGCTTGCGGTTGACCGTAATAATCCGCGGGTGAGCTCGTTATTTGAC
AGTTATCATCCGGGAATACTGCGGGCTTTGCATCAGGCTCACTTAGATTGTCGATATCATAAGCTCGATATCAGTATTTG
TGGCGAGTTAGCGGGCGAGCCTATGGGCGCCATTTTGTTGGTGGCCATGGGATACGATCAATTGAGTATGAATCAGGGTA
GTTTAGCGCGGATCAATTATCTCTTGCGCCGTGTCGCACGGGCCGATTTGGATCAATTGCTCGCTAAAGCCTTGAGCTTA
TCAAATGGCTTCCAAGTGCGCGAACTGGTTAAAGAATATTTGAACCAGCAAGGTCTCTCAGCAATTCTTAATTAA

Upstream 100 bases:

>100_bases
AGTTTGCGGTAACGGCATTGTCATTCCAGACCCTAGAAATACCTAGGAAACGGGGAAGACAAAAAACAACGGGCTGATTT
TCAAAAGAGGATTGAAAACA

Downstream 100 bases:

>100_bases
CTAATGTCGTCTTTTGCTTTAAGCTAAGGCCCTCAATTTATCACGCTGTAGGTACTCGTGTGGATAGTTTGTTGTCGGTG
TTTTTTATTTGCTTAGCTTT

Product: phosphoenolpyruvate-protein phosphotransferase PtsP

Products: NA

Alternate protein names: Enzyme I-Ntr; Phosphotransferase system, enzyme I [H]

Number of amino acids: Translated: 744; Mature: 744

Protein sequence:

>744_residues
MLNTLRDITQAVASAHSLETALEVLVSSTKAAMETQCCSIYILEEQELVLSATDGLEKSAVGRVRMPLTEGLVGLAAQRE
EAVNLADARLHPRFKLFPEVAEEEYRAFLAVPIIYQKAVVGVIVVQQASARQFSEGEEAFLMTLAAQLAMAVRGLKQKAQ
VSSHHQQILFQGTSASNGIAIAYAFVLGGEIPLEQPDMHSDDIVYESSRLTTAMVRCKEAIGALSQRFDREQDDEVVSIF
NALQLLLDGASLGGEYAREVQLGWAAESAVSRVSLRYIQQFLAMEDPYLKERASDIRDLGQKVLRQLIEPERLELEPDKP
VILITREADATMLAEFPRQKLAGIVTELGGVNSHAAILARALGVPAITGVEQLLSANIDQKLLVVNASRGQLLVSPSPAI
VGEYRSLISAQKALQRQYAQELALPSVTLDGSRIRLYLNAGLLSGVASEIAEGADGIGLYRTEIPFMLQQRFPSESEQVK
VYQQVLSAASGRPVVMRTLDVGGDKPLPYFPIKEDNPFLGWRGIRLSLDHPELFLVQLRAMLQAGGDGKQLSILLPMVSN
LDEIDQSLEYLQQAYVELKNDVNSNIVMPRIGIMLEVPAMLYQLDDVAKRVDFVSVGSNDLTQYLLAVDRNNPRVSSLFD
SYHPGILRALHQAHLDCRYHKLDISICGELAGEPMGAILLVAMGYDQLSMNQGSLARINYLLRRVARADLDQLLAKALSL
SNGFQVRELVKEYLNQQGLSAILN

Sequences:

>Translated_744_residues
MLNTLRDITQAVASAHSLETALEVLVSSTKAAMETQCCSIYILEEQELVLSATDGLEKSAVGRVRMPLTEGLVGLAAQRE
EAVNLADARLHPRFKLFPEVAEEEYRAFLAVPIIYQKAVVGVIVVQQASARQFSEGEEAFLMTLAAQLAMAVRGLKQKAQ
VSSHHQQILFQGTSASNGIAIAYAFVLGGEIPLEQPDMHSDDIVYESSRLTTAMVRCKEAIGALSQRFDREQDDEVVSIF
NALQLLLDGASLGGEYAREVQLGWAAESAVSRVSLRYIQQFLAMEDPYLKERASDIRDLGQKVLRQLIEPERLELEPDKP
VILITREADATMLAEFPRQKLAGIVTELGGVNSHAAILARALGVPAITGVEQLLSANIDQKLLVVNASRGQLLVSPSPAI
VGEYRSLISAQKALQRQYAQELALPSVTLDGSRIRLYLNAGLLSGVASEIAEGADGIGLYRTEIPFMLQQRFPSESEQVK
VYQQVLSAASGRPVVMRTLDVGGDKPLPYFPIKEDNPFLGWRGIRLSLDHPELFLVQLRAMLQAGGDGKQLSILLPMVSN
LDEIDQSLEYLQQAYVELKNDVNSNIVMPRIGIMLEVPAMLYQLDDVAKRVDFVSVGSNDLTQYLLAVDRNNPRVSSLFD
SYHPGILRALHQAHLDCRYHKLDISICGELAGEPMGAILLVAMGYDQLSMNQGSLARINYLLRRVARADLDQLLAKALSL
SNGFQVRELVKEYLNQQGLSAILN
>Mature_744_residues
MLNTLRDITQAVASAHSLETALEVLVSSTKAAMETQCCSIYILEEQELVLSATDGLEKSAVGRVRMPLTEGLVGLAAQRE
EAVNLADARLHPRFKLFPEVAEEEYRAFLAVPIIYQKAVVGVIVVQQASARQFSEGEEAFLMTLAAQLAMAVRGLKQKAQ
VSSHHQQILFQGTSASNGIAIAYAFVLGGEIPLEQPDMHSDDIVYESSRLTTAMVRCKEAIGALSQRFDREQDDEVVSIF
NALQLLLDGASLGGEYAREVQLGWAAESAVSRVSLRYIQQFLAMEDPYLKERASDIRDLGQKVLRQLIEPERLELEPDKP
VILITREADATMLAEFPRQKLAGIVTELGGVNSHAAILARALGVPAITGVEQLLSANIDQKLLVVNASRGQLLVSPSPAI
VGEYRSLISAQKALQRQYAQELALPSVTLDGSRIRLYLNAGLLSGVASEIAEGADGIGLYRTEIPFMLQQRFPSESEQVK
VYQQVLSAASGRPVVMRTLDVGGDKPLPYFPIKEDNPFLGWRGIRLSLDHPELFLVQLRAMLQAGGDGKQLSILLPMVSN
LDEIDQSLEYLQQAYVELKNDVNSNIVMPRIGIMLEVPAMLYQLDDVAKRVDFVSVGSNDLTQYLLAVDRNNPRVSSLFD
SYHPGILRALHQAHLDCRYHKLDISICGELAGEPMGAILLVAMGYDQLSMNQGSLARINYLLRRVARADLDQLLAKALSL
SNGFQVRELVKEYLNQQGLSAILN

Specific function: Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP)

COG id: COG3605

COG function: function code T; Signal transduction protein containing GAF and PtsI domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GAF domain [H]

Homologues:

Organism=Escherichia coli, GI1789193, Length=747, Percent_Identity=43.908969210174, Blast_Score=593, Evalue=1e-170,
Organism=Escherichia coli, GI1788756, Length=600, Percent_Identity=32.1666666666667, Blast_Score=297, Evalue=2e-81,
Organism=Escherichia coli, GI1788726, Length=541, Percent_Identity=34.3807763401109, Blast_Score=272, Evalue=6e-74,
Organism=Escherichia coli, GI48994992, Length=512, Percent_Identity=32.8125, Blast_Score=271, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003018
- InterPro:   IPR008279
- InterPro:   IPR006318
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR008731
- InterPro:   IPR015813 [H]

Pfam domain/function: PF01590 GAF; PF05524 PEP-utilisers_N; PF00391 PEP-utilizers; PF02896 PEP-utilizers_C [H]

EC number: =2.7.3.9 [H]

Molecular weight: Translated: 81771; Mature: 81771

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTLRDITQAVASAHSLETALEVLVSSTKAAMETQCCSIYILEEQELVLSATDGLEKSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCCCHHC
VGRVRMPLTEGLVGLAAQREEAVNLADARLHPRFKLFPEVAEEEYRAFLAVPIIYQKAVV
CCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHH
GVIVVQQASARQFSEGEEAFLMTLAAQLAMAVRGLKQKAQVSSHHQQILFQGTSASNGIA
HHHEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCE
IAYAFVLGGEIPLEQPDMHSDDIVYESSRLTTAMVRCKEAIGALSQRFDREQDDEVVSIF
EEEHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
NALQLLLDGASLGGEYAREVQLGWAAESAVSRVSLRYIQQFLAMEDPYLKERASDIRDLG
HHHHHHHCCHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QKVLRQLIEPERLELEPDKPVILITREADATMLAEFPRQKLAGIVTELGGVNSHAAILAR
HHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALGVPAITGVEQLLSANIDQKLLVVNASRGQLLVSPSPAIVGEYRSLISAQKALQRQYAQ
HHCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ELALPSVTLDGSRIRLYLNAGLLSGVASEIAEGADGIGLYRTEIPFMLQQRFPSESEQVK
HHCCCCEEECCCEEEEEEECHHHHHHHHHHHCCCCCCEEEHHHCHHHHHHHCCCCHHHHH
VYQQVLSAASGRPVVMRTLDVGGDKPLPYFPIKEDNPFLGWRGIRLSLDHPELFLVQLRA
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
MLQAGGDGKQLSILLPMVSNLDEIDQSLEYLQQAYVELKNDVNSNIVMPRIGIMLEVPAM
HHHCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHH
LYQLDDVAKRVDFVSVGSNDLTQYLLAVDRNNPRVSSLFDSYHPGILRALHQAHLDCRYH
HHHHHHHHHHHCEEECCCHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEE
KLDISICGELAGEPMGAILLVAMGYDQLSMNQGSLARINYLLRRVARADLDQLLAKALSL
EEHHHHHHHHCCCCCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SNGFQVRELVKEYLNQQGLSAILN
CCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNTLRDITQAVASAHSLETALEVLVSSTKAAMETQCCSIYILEEQELVLSATDGLEKSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEECCCCCHHC
VGRVRMPLTEGLVGLAAQREEAVNLADARLHPRFKLFPEVAEEEYRAFLAVPIIYQKAVV
CCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHH
GVIVVQQASARQFSEGEEAFLMTLAAQLAMAVRGLKQKAQVSSHHQQILFQGTSASNGIA
HHHEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCE
IAYAFVLGGEIPLEQPDMHSDDIVYESSRLTTAMVRCKEAIGALSQRFDREQDDEVVSIF
EEEHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
NALQLLLDGASLGGEYAREVQLGWAAESAVSRVSLRYIQQFLAMEDPYLKERASDIRDLG
HHHHHHHCCHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
QKVLRQLIEPERLELEPDKPVILITREADATMLAEFPRQKLAGIVTELGGVNSHAAILAR
HHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALGVPAITGVEQLLSANIDQKLLVVNASRGQLLVSPSPAIVGEYRSLISAQKALQRQYAQ
HHCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ELALPSVTLDGSRIRLYLNAGLLSGVASEIAEGADGIGLYRTEIPFMLQQRFPSESEQVK
HHCCCCEEECCCEEEEEEECHHHHHHHHHHHCCCCCCEEEHHHCHHHHHHHCCCCHHHHH
VYQQVLSAASGRPVVMRTLDVGGDKPLPYFPIKEDNPFLGWRGIRLSLDHPELFLVQLRA
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHH
MLQAGGDGKQLSILLPMVSNLDEIDQSLEYLQQAYVELKNDVNSNIVMPRIGIMLEVPAM
HHHCCCCCCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHH
LYQLDDVAKRVDFVSVGSNDLTQYLLAVDRNNPRVSSLFDSYHPGILRALHQAHLDCRYH
HHHHHHHHHHHCEEECCCHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEE
KLDISICGELAGEPMGAILLVAMGYDQLSMNQGSLARINYLLRRVARADLDQLLAKALSL
EEHHHHHHHHCCCCCCCEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SNGFQVRELVKEYLNQQGLSAILN
CCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 7896715; 8973315 [H]