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The map label for this gene is dtpB [H]

Identifier: 126173358

GI number: 126173358

Start: 1285074

End: 1286645

Strand: Reverse

Name: dtpB [H]

Synonym: Sbal_1117

Alternate gene names: 126173358

Gene position: 1286645-1285074 (Counterclockwise)

Preceding gene: 126173359

Following gene: 126173357

Centisome position: 25.09

GC content: 48.28

Gene sequence:

>1572_bases
ATGTTGGAAGCAAGCGATATGACTATTGGGACTGCTCCGGTAAGTAAAACACATTCATTTATGACAGTGTCTCTTATCGA
ATTATGGGAACGCTTTGGTTATTACGGTATGCAAGCGCTGATTGTGTACTTTATGGTGCAGCGCCTTGGCTTTGATGACT
CACGTGCAAACTTAGTATGGAGTGCCTGTGCGGCGCTCATTTATGTATCACCGGCGATTGGTGGTTGGGTTGGGGATAAA
ATCCTCGGCACTAAACGCACTATGCTGCTCGGCGCGGGGATTTTGTCTCTGGGTTATGCGCTGATGGCCGTACCCACTGA
AAATACGTGGTTTATGTTTTCAGCGCTCGGCGTGATTGTGGTCGGTAACGGCCTGTTCAAACCCAATGCCGGTAACTTAG
TTCGTAAAATTTACGAAGGTGACGATTCTAAAATCGACAGTGCGTTTACTATCTATTATATGGCGGTCAACGTCGGCTCA
ACCTTCTCTATGTTGCTGACGCCTTGGATTAAAGATTACGTCAACGCCCAGTATGGTAACGAATTCGGCTGGCATGCCGC
TTTTGCCGTGTGTTGTGTCGGCATATTGGTGGGGTTAGGCAACTATGCACTTATGCGTAAGAGTTTAGTCCATTACGGTT
CTGAGCCAGATACTCGCCCAGTGAATAAGAAAAGCCTCGCAATTGTGTTAGCTCTATCCGCATTGTCGGTTGTCGCTTCG
GCCATTATTCTGGAATATGAAGCGGTTGCCCGTGTCTTTGTTTACGCCGCTGGCGTAGCCGTATTGGCCATTTTCTTCCA
CTTGATCCGCACCAGCGAAACCAGTGAACGAGCGGGACTGATTGCGGCGCTGATCCTCACAGTGCAAACCGTGTTCTTCT
TTATCTTCTATCAACAAATGTCGACGTCATTGGCGCTGTTTGCCTTGCGTAAAGTGGACTGGGATTTCCAAATCTTTGGT
ACCCATTTGTGGACTTGGTCACCGGCCCAGTTCCAAGCATTGAATCCATTATGGATTATGGTGTTAAGTCCAATCTTGGC
TTGGAGTTATTCGTGGGCAGGTCGTAATGATAAAGACTTCTCTATCGCGGCGAAATTTGCCCTCGGTTTTGCCGTCGTGG
CTATAGGCTTCTTTATCTATGGCTTTGCCGGACAATTTGCCGTCAACGGCAAAACCTCTTCATGGATCATGATCTGGGGC
TATGCCTCTTACTCTTTAGGCGAATTGCTGGTGAGTGGTCTTGGTCTTGCCATGATTGCTCGCTACGTACCTGCACGCAT
GGGCGGCTTTATGATGGGCGCCTATTTCGTCGCCTCAGGTATTTCACAGTATCTGGGCGGTGTGGTCGCTAACTTCGCCA
GTGTGCCAAAAGATTTAGTCGATCCACTGCAAACCTTGCCCGTATACACCAGTCTATTTAATAAGTTAGGTATCGCGGCT
GTGGTTTGTACCTTTATCGCCCTTGCGGTATTACCGCTAATGCGTCGCCTGACTGAGACTCACCATTCACATAATAATAC
TGAGAATGAAAGTGCTGCGGCATCGCTAAGGGATGTGAAAGCCGAGCAGTAA

Upstream 100 bases:

>100_bases
TTCATCAATTCATTTGTAACAAAGTCTGTTTTACCAGTCTCTGCCATTGGTTTGCTTGGGTTATCGCCTTATACTTTTGA
GCTCAAATATTAAAACAACA

Downstream 100 bases:

>100_bases
TGCGCGACTGACAATAGCGATTTATCTATTGCATAACATCAACTGCCGATAGCCCTGCTATCGGCAGTTTTTTTATCACT
TCACTTAGTGATACCAATCA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MLEASDMTIGTAPVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSPAIGGWVGDK
ILGTKRTMLLGAGILSLGYALMAVPTENTWFMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGS
TFSMLLTPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGLGNYALMRKSLVHYGSEPDTRPVNKKSLAIVLALSALSVVAS
AIILEYEAVARVFVYAAGVAVLAIFFHLIRTSETSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRKVDWDFQIFG
THLWTWSPAQFQALNPLWIMVLSPILAWSYSWAGRNDKDFSIAAKFALGFAVVAIGFFIYGFAGQFAVNGKTSSWIMIWG
YASYSLGELLVSGLGLAMIARYVPARMGGFMMGAYFVASGISQYLGGVVANFASVPKDLVDPLQTLPVYTSLFNKLGIAA
VVCTFIALAVLPLMRRLTETHHSHNNTENESAAASLRDVKAEQ

Sequences:

>Translated_523_residues
MLEASDMTIGTAPVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSPAIGGWVGDK
ILGTKRTMLLGAGILSLGYALMAVPTENTWFMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGS
TFSMLLTPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGLGNYALMRKSLVHYGSEPDTRPVNKKSLAIVLALSALSVVAS
AIILEYEAVARVFVYAAGVAVLAIFFHLIRTSETSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRKVDWDFQIFG
THLWTWSPAQFQALNPLWIMVLSPILAWSYSWAGRNDKDFSIAAKFALGFAVVAIGFFIYGFAGQFAVNGKTSSWIMIWG
YASYSLGELLVSGLGLAMIARYVPARMGGFMMGAYFVASGISQYLGGVVANFASVPKDLVDPLQTLPVYTSLFNKLGIAA
VVCTFIALAVLPLMRRLTETHHSHNNTENESAAASLRDVKAEQ
>Mature_523_residues
MLEASDMTIGTAPVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSACAALIYVSPAIGGWVGDK
ILGTKRTMLLGAGILSLGYALMAVPTENTWFMFSALGVIVVGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGS
TFSMLLTPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGLGNYALMRKSLVHYGSEPDTRPVNKKSLAIVLALSALSVVAS
AIILEYEAVARVFVYAAGVAVLAIFFHLIRTSETSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRKVDWDFQIFG
THLWTWSPAQFQALNPLWIMVLSPILAWSYSWAGRNDKDFSIAAKFALGFAVVAIGFFIYGFAGQFAVNGKTSSWIMIWG
YASYSLGELLVSGLGLAMIARYVPARMGGFMMGAYFVASGISQYLGGVVANFASVPKDLVDPLQTLPVYTSLFNKLGIAA
VVCTFIALAVLPLMRRLTETHHSHNNTENESAAASLRDVKAEQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=405, Percent_Identity=21.9753086419753, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI226371746, Length=373, Percent_Identity=22.5201072386059, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1789911, Length=493, Percent_Identity=38.7423935091278, Blast_Score=344, Evalue=6e-96,
Organism=Escherichia coli, GI1787922, Length=488, Percent_Identity=37.9098360655738, Blast_Score=340, Evalue=2e-94,
Organism=Escherichia coli, GI1790572, Length=508, Percent_Identity=28.740157480315, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1786927, Length=492, Percent_Identity=28.0487804878049, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71987453, Length=372, Percent_Identity=25.5376344086022, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17569141, Length=390, Percent_Identity=21.5384615384615, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639581, Length=207, Percent_Identity=28.5024154589372, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639585, Length=202, Percent_Identity=27.2277227722772, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639583, Length=195, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571098, Length=336, Percent_Identity=25, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571102, Length=336, Percent_Identity=25, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571100, Length=336, Percent_Identity=25, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 57189; Mature: 57189

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEASDMTIGTAPVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVW
CCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHH
SACAALIYVSPAIGGWVGDKILGTKRTMLLGAGILSLGYALMAVPTENTWFMFSALGVIV
HHHHHHHHHCCHHCCHHCCHHHCCHHHHHHHHHHHHHCHHHEEECCCCCCHHHHHHCHHE
VGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLLTPWIKDYVNAQYGN
ECCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCC
EFGWHAAFAVCCVGILVGLGNYALMRKSLVHYGSEPDTRPVNKKSLAIVLALSALSVVAS
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AIILEYEAVARVFVYAAGVAVLAIFFHLIRTSETSERAGLIAALILTVQTVFFFIFYQQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
STSLALFALRKVDWDFQIFGTHLWTWSPAQFQALNPLWIMVLSPILAWSYSWAGRNDKDF
HHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCH
SIAAKFALGFAVVAIGFFIYGFAGQFAVNGKTSSWIMIWGYASYSLGELLVSGLGLAMIA
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHH
RYVPARMGGFMMGAYFVASGISQYLGGVVANFASVPKDLVDPLQTLPVYTSLFNKLGIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VVCTFIALAVLPLMRRLTETHHSHNNTENESAAASLRDVKAEQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLEASDMTIGTAPVSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVW
CCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHH
SACAALIYVSPAIGGWVGDKILGTKRTMLLGAGILSLGYALMAVPTENTWFMFSALGVIV
HHHHHHHHHCCHHCCHHCCHHHCCHHHHHHHHHHHHHCHHHEEECCCCCCHHHHHHCHHE
VGNGLFKPNAGNLVRKIYEGDDSKIDSAFTIYYMAVNVGSTFSMLLTPWIKDYVNAQYGN
ECCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCC
EFGWHAAFAVCCVGILVGLGNYALMRKSLVHYGSEPDTRPVNKKSLAIVLALSALSVVAS
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AIILEYEAVARVFVYAAGVAVLAIFFHLIRTSETSERAGLIAALILTVQTVFFFIFYQQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
STSLALFALRKVDWDFQIFGTHLWTWSPAQFQALNPLWIMVLSPILAWSYSWAGRNDKDF
HHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCH
SIAAKFALGFAVVAIGFFIYGFAGQFAVNGKTSSWIMIWGYASYSLGELLVSGLGLAMIA
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHH
RYVPARMGGFMMGAYFVASGISQYLGGVVANFASVPKDLVDPLQTLPVYTSLFNKLGIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VVCTFIALAVLPLMRRLTETHHSHNNTENESAAASLRDVKAEQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA