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The map label for this gene is apbE [H]

Identifier: 126173175

GI number: 126173175

Start: 1068589

End: 1069635

Strand: Direct

Name: apbE [H]

Synonym: Sbal_0930

Alternate gene names: 126173175

Gene position: 1068589-1069635 (Clockwise)

Preceding gene: 126173174

Following gene: 126173176

Centisome position: 20.84

GC content: 46.42

Gene sequence:

>1047_bases
ATGTTTCAGACCTTAAAGATCAATACCTCAGCACTAAAGCATTCATTTAACTGGCTAGTCCTCGTAGGGCTGGCCTTTTT
TGTTTCAGCCTGTTCTAAGCAGAACGAAGTCATTTCGTTAGCGGGCAGCACTATGGGAACGACTTACCATATTAAAGTCG
TACCGAATGAGCAGATGCCGACAGCGCAGTTACTTCAAGCGGAAATTGATTTAGCCCTTGAGCTGGTCAATGACCAGATG
TCGACGTATCGCCCTGATTCAGAGTTATCCCGTTTCAACCAGTTGCCATTGGAGCAAAGCGTTGAAGTCTCACCGGATAC
CATCAAAGTGGTGCAAGAGGGAGTACGTTTATATCAAGTGACGGATAAGGCACTTGATATTACCTTAGGTCCTTTAGTTA
ACCTGTGGGGATTTGGGCCAGATAAGCGTCCAACAAAGGTCCCGAGTCAGGCCGATATTGATGCGGCAAAAGCCAAAACC
GGTATTAGTGAACTTTCCATTGAAGGTAACCGTCTAACTAAGCACAACGCCCATTTATACGTAGACCTATCGTCGATTGC
CAAAGGGTTTGGGGTTGATAAAGTGGCTTCCATTCTTGATAAATACCACGCGACTGGGTATTTAGTTGAAATTGGTGGCG
AGCTCAGCATTAAAGGTGCTAAAGGCGATGGCAGCTCTTGGCGCGTTGCCATAGAGCAACCAACAGATGACGGTTCTGAA
GCCGTACAGCAGGTTATCTCACCAGGTACTATGGCGATGGCGACCTCGGGCGATTATCGTAATTATTATGAGGAAGACGG
CCAACGTTTTACCCATATAATTGATCCGCGTACCGGTTTGCCGATAAATCATAAGCTAGCATCCGTGACCGTATTGCATC
AAAATTGTATGACGGCCGATGGTTTTGCGACGGCTATGATGGTTTTGGGCACAGAAGCATCATTGGAGCTTGCCAAGAAG
GAACACTTGGCGATAATGCTTATCGAAAAGCAAGGCGACGGATTTAAGGTCTACTATAGCGACGCCTTCAAGCCTTTCCT
TATTTAG

Upstream 100 bases:

>100_bases
AATGTTCATTAGTCCTAGATAGAAAAGTTGCAGATGTTGAGGATAATCTCTCATCTGCAACTTTTGTATTTAAGGGCCCA
AATAAGAGTAGTAGGTCACT

Downstream 100 bases:

>100_bases
TTTTTGGAGTAAACCATGACCTCTTTTATCGCGGCATTTGTGATTTTGTTATTATTCTTTTTGCTCATGTCGATTGGTTA
TCTCATCAAGCGCAAAGCCG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MFQTLKINTSALKHSFNWLVLVGLAFFVSACSKQNEVISLAGSTMGTTYHIKVVPNEQMPTAQLLQAEIDLALELVNDQM
STYRPDSELSRFNQLPLEQSVEVSPDTIKVVQEGVRLYQVTDKALDITLGPLVNLWGFGPDKRPTKVPSQADIDAAKAKT
GISELSIEGNRLTKHNAHLYVDLSSIAKGFGVDKVASILDKYHATGYLVEIGGELSIKGAKGDGSSWRVAIEQPTDDGSE
AVQQVISPGTMAMATSGDYRNYYEEDGQRFTHIIDPRTGLPINHKLASVTVLHQNCMTADGFATAMMVLGTEASLELAKK
EHLAIMLIEKQGDGFKVYYSDAFKPFLI

Sequences:

>Translated_348_residues
MFQTLKINTSALKHSFNWLVLVGLAFFVSACSKQNEVISLAGSTMGTTYHIKVVPNEQMPTAQLLQAEIDLALELVNDQM
STYRPDSELSRFNQLPLEQSVEVSPDTIKVVQEGVRLYQVTDKALDITLGPLVNLWGFGPDKRPTKVPSQADIDAAKAKT
GISELSIEGNRLTKHNAHLYVDLSSIAKGFGVDKVASILDKYHATGYLVEIGGELSIKGAKGDGSSWRVAIEQPTDDGSE
AVQQVISPGTMAMATSGDYRNYYEEDGQRFTHIIDPRTGLPINHKLASVTVLHQNCMTADGFATAMMVLGTEASLELAKK
EHLAIMLIEKQGDGFKVYYSDAFKPFLI
>Mature_348_residues
MFQTLKINTSALKHSFNWLVLVGLAFFVSACSKQNEVISLAGSTMGTTYHIKVVPNEQMPTAQLLQAEIDLALELVNDQM
STYRPDSELSRFNQLPLEQSVEVSPDTIKVVQEGVRLYQVTDKALDITLGPLVNLWGFGPDKRPTKVPSQADIDAAKAKT
GISELSIEGNRLTKHNAHLYVDLSSIAKGFGVDKVASILDKYHATGYLVEIGGELSIKGAKGDGSSWRVAIEQPTDDGSE
AVQQVISPGTMAMATSGDYRNYYEEDGQRFTHIIDPRTGLPINHKLASVTVLHQNCMTADGFATAMMVLGTEASLELAKK
EHLAIMLIEKQGDGFKVYYSDAFKPFLI

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=346, Percent_Identity=41.0404624277457, Blast_Score=266, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 38071; Mature: 38071

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTLKINTSALKHSFNWLVLVGLAFFVSACSKQNEVISLAGSTMGTTYHIKVVPNEQMP
CCEEEEECHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEECCCCCC
TAQLLQAEIDLALELVNDQMSTYRPDSELSRFNQLPLEQSVEVSPDTIKVVQEGVRLYQV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHEEEE
TDKALDITLGPLVNLWGFGPDKRPTKVPSQADIDAAKAKTGISELSIEGNRLTKHNAHLY
ECCHHEEEHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHEEECCCEEEECCCEEE
VDLSSIAKGFGVDKVASILDKYHATGYLVEIGGELSIKGAKGDGSSWRVAIEQPTDDGSE
EEHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCEEEEEECCCCCHHH
AVQQVISPGTMAMATSGDYRNYYEEDGQRFTHIIDPRTGLPINHKLASVTVLHQNCMTAD
HHHHHHCCCCEEEEECCCHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEEHHCCCCCC
GFATAMMVLGTEASLELAKKEHLAIMLIEKQGDGFKVYYSDAFKPFLI
HHHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MFQTLKINTSALKHSFNWLVLVGLAFFVSACSKQNEVISLAGSTMGTTYHIKVVPNEQMP
CCEEEEECHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEEEECCCCCC
TAQLLQAEIDLALELVNDQMSTYRPDSELSRFNQLPLEQSVEVSPDTIKVVQEGVRLYQV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHEEEE
TDKALDITLGPLVNLWGFGPDKRPTKVPSQADIDAAKAKTGISELSIEGNRLTKHNAHLY
ECCHHEEEHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCHHHEEECCCEEEECCCEEE
VDLSSIAKGFGVDKVASILDKYHATGYLVEIGGELSIKGAKGDGSSWRVAIEQPTDDGSE
EEHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCEEEEEECCCCCHHH
AVQQVISPGTMAMATSGDYRNYYEEDGQRFTHIIDPRTGLPINHKLASVTVLHQNCMTAD
HHHHHHCCCCEEEEECCCHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEEHHCCCCCC
GFATAMMVLGTEASLELAKKEHLAIMLIEKQGDGFKVYYSDAFKPFLI
HHHHHHHHHCCCHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]