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The map label for this gene is erg3 [H]

Identifier: 126172965

GI number: 126172965

Start: 810353

End: 811219

Strand: Direct

Name: erg3 [H]

Synonym: Sbal_0717

Alternate gene names: 126172965

Gene position: 810353-811219 (Clockwise)

Preceding gene: 126172964

Following gene: 126172966

Centisome position: 15.8

GC content: 46.94

Gene sequence:

>867_bases
ATGGATATCGCCTCGCTGATCCAGCACCCCGAAGTGTTACTGCTCGTGCTCGCGCCGTTGTTTTTCGTGTGTATTTTACT
GGAATGGTATTTTGGCGATAAAAGACAAAAGCTACCGTTAACTGCACGTTATCGCGGCCAAGAAGTACTGTGTAATTTCA
GCCTTGCGGCCATGCATCAAGGCGCCGATCTACTCACTGGCTTGTTGATCGCTAAGCTGTATCTGGCGATGTTTGGTTGG
AAATTATTCGATATTGAAATGGGCCCATTAAGCTTTATTGCTTTGATGATCGCGCAGGACTTTTGTTATTACTGGTTCCA
CAGGGCGAGCCATAGAGTGCGCTGGATGTGGGCGGCTCACGTGGTGCACCATAGCTCTGAGAATATGAATTTTAGCACGG
CGTTTCGCCAGAGTTTAATGTATCCGTTTGCGGGCATGTGGGTGTTTTGGTTGCCGCTGGTGGTCATAGGTTTCGACCCA
AACTGGGTGGTGTTTGTGGTATTACTCAATCTAGGATTGCAATTTTTTGTGCATACCCAAGCGATTAAATCACTCGGACC
GCTGGAATGGGTCTTTAATACACCGTCTCATCACAGGGTGCACCACGGTCGTAATCCCCAATATATAGATAAAAACTATG
CGGGCGTGCTGATTATTTGGGACAAGCTGTTTGGCACTTTTGAGCCCGAAGTGGAGACAGTGATTTACGGTATCACTAAG
CCTGTGAATAGTTTTAATCCTCTTAAAGTGACGTTTAGCGAATGGCGAGACATGTTTGCTGAGGTCACCGCGACAGGCTT
GAGTGTTAAACAACGACTACGTATCTTGTTTGCTCCGCCTTCCAGCAGCTTAAAAAGCGAGGAATAA

Upstream 100 bases:

>100_bases
TGTGTTGTTGCGTTTAATGCGGTTTATAAAATTCGCTCAGAATCGATATAAAAAACACTAAAAATAATCATAAAACAACA
AGAGAACAGGACGACCTTAT

Downstream 100 bases:

>100_bases
CAATCCACTGCATTTTCCAAGTTAAATAGCGCAAATGGCTAATAGAGTCTTGAATTTAGCCTTGCTAGCCTATATTCCGT
TTTTTGCCACTGTTTTGGTG

Product: sterol desaturase family protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MDIASLIQHPEVLLLVLAPLFFVCILLEWYFGDKRQKLPLTARYRGQEVLCNFSLAAMHQGADLLTGLLIAKLYLAMFGW
KLFDIEMGPLSFIALMIAQDFCYYWFHRASHRVRWMWAAHVVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVVIGFDP
NWVVFVVLLNLGLQFFVHTQAIKSLGPLEWVFNTPSHHRVHHGRNPQYIDKNYAGVLIIWDKLFGTFEPEVETVIYGITK
PVNSFNPLKVTFSEWRDMFAEVTATGLSVKQRLRILFAPPSSSLKSEE

Sequences:

>Translated_288_residues
MDIASLIQHPEVLLLVLAPLFFVCILLEWYFGDKRQKLPLTARYRGQEVLCNFSLAAMHQGADLLTGLLIAKLYLAMFGW
KLFDIEMGPLSFIALMIAQDFCYYWFHRASHRVRWMWAAHVVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVVIGFDP
NWVVFVVLLNLGLQFFVHTQAIKSLGPLEWVFNTPSHHRVHHGRNPQYIDKNYAGVLIIWDKLFGTFEPEVETVIYGITK
PVNSFNPLKVTFSEWRDMFAEVTATGLSVKQRLRILFAPPSSSLKSEE
>Mature_288_residues
MDIASLIQHPEVLLLVLAPLFFVCILLEWYFGDKRQKLPLTARYRGQEVLCNFSLAAMHQGADLLTGLLIAKLYLAMFGW
KLFDIEMGPLSFIALMIAQDFCYYWFHRASHRVRWMWAAHVVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVVIGFDP
NWVVFVVLLNLGLQFFVHTQAIKSLGPLEWVFNTPSHHRVHHGRNPQYIDKNYAGVLIIWDKLFGTFEPEVETVIYGITK
PVNSFNPLKVTFSEWRDMFAEVTATGLSVKQRLRILFAPPSSSLKSEE

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=176, Percent_Identity=53.9772727272727, Blast_Score=187, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI25144659, Length=184, Percent_Identity=42.9347826086957, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 33345; Mature: 33345

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIASLIQHPEVLLLVLAPLFFVCILLEWYFGDKRQKLPLTARYRGQEVLCNFSLAAMHQ
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEECHHHHHHHC
GADLLTGLLIAKLYLAMFGWKLFDIEMGPLSFIALMIAQDFCYYWFHRASHRVRWMWAAH
CHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
VVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVVIGFDPNWVVFVVLLNLGLQFFVHTQ
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AIKSLGPLEWVFNTPSHHRVHHGRNPQYIDKNYAGVLIIWDKLFGTFEPEVETVIYGITK
HHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCHHHEEEECCC
PVNSFNPLKVTFSEWRDMFAEVTATGLSVKQRLRILFAPPSSSLKSEE
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDIASLIQHPEVLLLVLAPLFFVCILLEWYFGDKRQKLPLTARYRGQEVLCNFSLAAMHQ
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEECHHHHHHHC
GADLLTGLLIAKLYLAMFGWKLFDIEMGPLSFIALMIAQDFCYYWFHRASHRVRWMWAAH
CHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHH
VVHHSSENMNFSTAFRQSLMYPFAGMWVFWLPLVVIGFDPNWVVFVVLLNLGLQFFVHTQ
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
AIKSLGPLEWVFNTPSHHRVHHGRNPQYIDKNYAGVLIIWDKLFGTFEPEVETVIYGITK
HHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCHHHEEEECCC
PVNSFNPLKVTFSEWRDMFAEVTATGLSVKQRLRILFAPPSSSLKSEE
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]