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The map label for this gene is hlyB [H]

Identifier: 126172939

GI number: 126172939

Start: 784491

End: 786353

Strand: Direct

Name: hlyB [H]

Synonym: Sbal_0691

Alternate gene names: 126172939

Gene position: 784491-786353 (Clockwise)

Preceding gene: 126172935

Following gene: 126172943

Centisome position: 15.3

GC content: 47.13

Gene sequence:

>1863_bases
ATGTTTATCCGCTCAAAGTTGTTACTCAGCGCAGCTGTGTCTATTTCGGCATTAGTTGCCATGTTTGGATTACAACTCCA
TTCAAATTCGGTTAAGTCGGAGCTCTCCCATGCCGCTCAAAATGTGCTTGAGTTAGAGCGCGACGTCTTAATTCTGCGTA
AAAACGAAAAGGATTTCTTCGCTCGCAAGGATTTAAAATATGCCGAGCTACATAAGCAAAGCCACATGAAAATCGACAGC
ATTGTCCCGGAGTTAGAGAAAGTCTTTAAAGAATATGGTGTGTCCAAGGCATCGCTTGAAAGTTTCGACAGTCATTTAAA
TCAGTATCAAGCTGCTTTCTCTGAAGTGGTGCAGCTACAGCAGGAGATTGGCTTAACACCCAAAACGGGGTTGTACGGCA
CACTGCGTTCGGCGGTGCACAATGTTGAAACGCTGCTTAAGCAATACAATCAGCTCGAACTCGAAGTGGCTATGCTGCAA
CTGAGACGTAATGAAAAAGATTTTATGCTGCGCCGTGAGCTAAGTTATGTTGAAACCTTCGATGCCAATATTGGCAAGTT
TAATGACAAACTGCGTTCATCGAGCTTAGATGCTGATACCCAAAATAAAATTGCAGAGCTTATTACTCAGTATCAGAAAG
ATTTTAAAAGCTTAACCAATAAAGAGCAGCAACTCGGTTTGACCGAGAAAGATGGCACTATGGCGCGTCTTGTCGCGGCC
AACCTACAAATTGAAAGCAGCGCGAATGACTTACATAACCTAGCGCTTAAGGCGATTGATGATGCTGAGAGCAGCAGCGT
TAATGTAGGTATTGCTGTGTTTATCTTTATCACGTTGCTGCTATCTTTCATCACCTATCTAATTATCCGCAGTATCATCG
CGCCGGTTGAGCGTATCACGCAGATCATTGCTCGCATCGAAGTGAGTAAAGATCTGACTTTGAGATGCGATGCGTCCACG
CAAGATGAACTTGGCGAAATTGCACAGCACTTCAATAGTATGGTTAGCAGCTTCCAGCAACTGATTGAGCAAGTGATTGA
GTCGGTCGCGACAATTAACACCTCCTGTAAGCGCGTATCCGAAAATGCCATGCTTGCCTCTGAAGGCGTAGGTCAACAGC
TCAATGAGACTGACATGGTTGCAACGGCGATCACTGAAATGGGCGCAACCATTGACGAAATTGCTAAAACAACTGAGTTA
GCGGCATCAAAAGCGGGCCAGACCCACGATAATGCGCAAAGTGGCCAATTAGAAGTCGAGCAAACGATTCATAAAATCCA
GTCACTTGCTGAGCAGCTCAATAGCTCTGCTGCGGTCGTTAATGAGCTGGAACGTGACAGCGAGACAATCGGTAGCGTGT
TAGATGTGATCCGCGGTATTGCTGAGCAGACCAACCTCTTGGCCTTGAATGCGGCGATTGAAGCGGCGCGCGCGGGTGAG
CAGGGCCGTGGTTTTGCCGTGGTTGCCGATGAGGTGCGTAACTTAGCGATGCGGACTCAATCGTCAACCCAAGAGATTGC
GAACATTATTCAGACCTTACAGACGCGTACTCGCTCGATTGTGCAATTGATGGAATCGAGCCAAAAACAAGGCGTTGAGA
GTGCGGAGCAGGCTGCTAGTGCTGGTGCGTTACTCAAGCTTATTAATACCGATGTGCGTAACATCATGGACATGAGTACT
CAAATTGCCGCGGCGATTGAAGAGCAAAGCATGGTGGCGGCAGAAGTGAACAAGAACGTGGTGGTGATCCGCGATATCGC
CGAAGAATCCTCCCATGCGGCAGATGCCAATGCGTCGGCATCGGATGAGCTGAAAGCGCAGGCTGAATTCTTATTCCGTG
CGGTCAGTAATTTTAAAATCTAA

Upstream 100 bases:

>100_bases
GTATTGGATATGAACTTTTCATGTATTGCTACACTTGCGCTGTTAAAGGCCTAATTTACAGCTATCTTTTTAAGATAGAT
TATTTATTCGGGGACTTTCT

Downstream 100 bases:

>100_bases
TATTTAAAAGCCAACTCTAATCTAATGAGCAGAAGCTAGCTTAGAAAATACACTAACAAAAACGCACTCCGAGGAGTGCG
TTTTTATGTCTGAGTGATTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MFIRSKLLLSAAVSISALVAMFGLQLHSNSVKSELSHAAQNVLELERDVLILRKNEKDFFARKDLKYAELHKQSHMKIDS
IVPELEKVFKEYGVSKASLESFDSHLNQYQAAFSEVVQLQQEIGLTPKTGLYGTLRSAVHNVETLLKQYNQLELEVAMLQ
LRRNEKDFMLRRELSYVETFDANIGKFNDKLRSSSLDADTQNKIAELITQYQKDFKSLTNKEQQLGLTEKDGTMARLVAA
NLQIESSANDLHNLALKAIDDAESSSVNVGIAVFIFITLLLSFITYLIIRSIIAPVERITQIIARIEVSKDLTLRCDAST
QDELGEIAQHFNSMVSSFQQLIEQVIESVATINTSCKRVSENAMLASEGVGQQLNETDMVATAITEMGATIDEIAKTTEL
AASKAGQTHDNAQSGQLEVEQTIHKIQSLAEQLNSSAAVVNELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRNLAMRTQSSTQEIANIIQTLQTRTRSIVQLMESSQKQGVESAEQAASAGALLKLINTDVRNIMDMST
QIAAAIEEQSMVAAEVNKNVVVIRDIAEESSHAADANASASDELKAQAEFLFRAVSNFKI

Sequences:

>Translated_620_residues
MFIRSKLLLSAAVSISALVAMFGLQLHSNSVKSELSHAAQNVLELERDVLILRKNEKDFFARKDLKYAELHKQSHMKIDS
IVPELEKVFKEYGVSKASLESFDSHLNQYQAAFSEVVQLQQEIGLTPKTGLYGTLRSAVHNVETLLKQYNQLELEVAMLQ
LRRNEKDFMLRRELSYVETFDANIGKFNDKLRSSSLDADTQNKIAELITQYQKDFKSLTNKEQQLGLTEKDGTMARLVAA
NLQIESSANDLHNLALKAIDDAESSSVNVGIAVFIFITLLLSFITYLIIRSIIAPVERITQIIARIEVSKDLTLRCDAST
QDELGEIAQHFNSMVSSFQQLIEQVIESVATINTSCKRVSENAMLASEGVGQQLNETDMVATAITEMGATIDEIAKTTEL
AASKAGQTHDNAQSGQLEVEQTIHKIQSLAEQLNSSAAVVNELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRNLAMRTQSSTQEIANIIQTLQTRTRSIVQLMESSQKQGVESAEQAASAGALLKLINTDVRNIMDMST
QIAAAIEEQSMVAAEVNKNVVVIRDIAEESSHAADANASASDELKAQAEFLFRAVSNFKI
>Mature_620_residues
MFIRSKLLLSAAVSISALVAMFGLQLHSNSVKSELSHAAQNVLELERDVLILRKNEKDFFARKDLKYAELHKQSHMKIDS
IVPELEKVFKEYGVSKASLESFDSHLNQYQAAFSEVVQLQQEIGLTPKTGLYGTLRSAVHNVETLLKQYNQLELEVAMLQ
LRRNEKDFMLRRELSYVETFDANIGKFNDKLRSSSLDADTQNKIAELITQYQKDFKSLTNKEQQLGLTEKDGTMARLVAA
NLQIESSANDLHNLALKAIDDAESSSVNVGIAVFIFITLLLSFITYLIIRSIIAPVERITQIIARIEVSKDLTLRCDAST
QDELGEIAQHFNSMVSSFQQLIEQVIESVATINTSCKRVSENAMLASEGVGQQLNETDMVATAITEMGATIDEIAKTTEL
AASKAGQTHDNAQSGQLEVEQTIHKIQSLAEQLNSSAAVVNELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRNLAMRTQSSTQEIANIIQTLQTRTRSIVQLMESSQKQGVESAEQAASAGALLKLINTDVRNIMDMST
QIAAAIEEQSMVAAEVNKNVVVIRDIAEESSHAADANASASDELKAQAEFLFRAVSNFKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=353, Percent_Identity=29.4617563739377, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI2367378, Length=323, Percent_Identity=28.4829721362229, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788195, Length=287, Percent_Identity=32.0557491289199, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788194, Length=235, Percent_Identity=32.7659574468085, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789453, Length=373, Percent_Identity=24.1286863270777, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68199; Mature: 68199

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIRSKLLLSAAVSISALVAMFGLQLHSNSVKSELSHAAQNVLELERDVLILRKNEKDFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHH
ARKDLKYAELHKQSHMKIDSIVPELEKVFKEYGVSKASLESFDSHLNQYQAAFSEVVQLQ
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEIGLTPKTGLYGTLRSAVHNVETLLKQYNQLELEVAMLQLRRNEKDFMLRRELSYVETF
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DANIGKFNDKLRSSSLDADTQNKIAELITQYQKDFKSLTNKEQQLGLTEKDGTMARLVAA
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHH
NLQIESSANDLHNLALKAIDDAESSSVNVGIAVFIFITLLLSFITYLIIRSIIAPVERIT
HCEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIIARIEVSKDLTLRCDASTQDELGEIAQHFNSMVSSFQQLIEQVIESVATINTSCKRVS
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAMLASEGVGQQLNETDMVATAITEMGATIDEIAKTTELAASKAGQTHDNAQSGQLEVE
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
QTIHKIQSLAEQLNSSAAVVNELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
QGRGFAVVADEVRNLAMRTQSSTQEIANIIQTLQTRTRSIVQLMESSQKQGVESAEQAAS
CCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AGALLKLINTDVRNIMDMSTQIAAAIEEQSMVAAEVNKNVVVIRDIAEESSHAADANASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCCC
SDELKAQAEFLFRAVSNFKI
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFIRSKLLLSAAVSISALVAMFGLQLHSNSVKSELSHAAQNVLELERDVLILRKNEKDFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHH
ARKDLKYAELHKQSHMKIDSIVPELEKVFKEYGVSKASLESFDSHLNQYQAAFSEVVQLQ
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEIGLTPKTGLYGTLRSAVHNVETLLKQYNQLELEVAMLQLRRNEKDFMLRRELSYVETF
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DANIGKFNDKLRSSSLDADTQNKIAELITQYQKDFKSLTNKEQQLGLTEKDGTMARLVAA
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHH
NLQIESSANDLHNLALKAIDDAESSSVNVGIAVFIFITLLLSFITYLIIRSIIAPVERIT
HCEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QIIARIEVSKDLTLRCDASTQDELGEIAQHFNSMVSSFQQLIEQVIESVATINTSCKRVS
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAMLASEGVGQQLNETDMVATAITEMGATIDEIAKTTELAASKAGQTHDNAQSGQLEVE
HHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
QTIHKIQSLAEQLNSSAAVVNELERDSETIGSVLDVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
QGRGFAVVADEVRNLAMRTQSSTQEIANIIQTLQTRTRSIVQLMESSQKQGVESAEQAAS
CCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AGALLKLINTDVRNIMDMSTQIAAAIEEQSMVAAEVNKNVVVIRDIAEESSHAADANASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCCC
SDELKAQAEFLFRAVSNFKI
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]