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The map label for this gene is btuB [H]

Identifier: 126172912

GI number: 126172912

Start: 752279

End: 754237

Strand: Direct

Name: btuB [H]

Synonym: Sbal_0663

Alternate gene names: 126172912

Gene position: 752279-754237 (Clockwise)

Preceding gene: 126172911

Following gene: 126172913

Centisome position: 14.67

GC content: 48.09

Gene sequence:

>1959_bases
ATGGGAACAAATCCAACCAAAATCGCGCTGCTGATCGGTAGCCTTTGCAGTTTTTCCGTTATCGCGCCCGCTATGGCGGC
AGACGATACCAGCACAGCGAAAGTCAACGAGCATCTTGTCGTGATCGGCCGCTCTGACAATACCCCGTTAAATATTGCCG
CGAATGTGAATGTGATTGACGCTGCGGCGATTGAAATGAGCGGTGCCACTAGTGTGACTGAGGTTTTACGCGGTCAAAGC
GGTATTCAAATTTCGGATAATAACATCGGTACTAGCTTTGCGATGCGTGGCTTTAGCGCCAGCACTGCTGTGAATAACAC
GCTGATTTTACTTGATGGTCGTCGCCTCAATAATATCGATATCGCTGCTCCTAGTCTTAATGCCATACCGCTTAACCAAG
TCGAGCGCATCGAAATTTTATCGGGTAGTGCGGGTGTGCTTTATGGTGACCAAGCGGTAGGCGGCGTGATCAATATTGTC
ACTAAATCCCCTGAAAATACCGGCGGTAGCGTGCAGTTATCCGGCGGCAGCTTTGATACCTATGAAGGTCGCGGTGATGT
GTCTGGCGCGATCAACAAGGATTGGCGTTACTTTTTCACTGGTAGCTATAACCAAGGTGACAACTACCGCAAGCATAATG
CCAATGAAACAGGGTCGATTTTAGGTCGCATTCAATATAAAACGGCCACAGACTCCTTCTTTGTTGAAACTAGCTACTAC
GACAACGATCGTGAAAATCCGGGCTCGCTGACTGAAAAGCAATTTAAAGATAACCCACGTTACTCTGGTAACGATAAGCA
ATATTCCCATGAAATGACTACGGCGGCGCGCACGGGTTACCAGCATCAGCTCAATCCAAACTGGGCGCTGGCGGCGGATT
TAGATTACAGCGATACCTTAGTGTCATCATTGAACTGGGGACAGAGCCGTAACACACGCTCACTGTTGATGTTTAGTCCT
AAAGCGTTAGCGAACTACAGTACGCGTCAAGGTGAGCTAAACCTAGTCACAGGTTTAGACATCAGCCGTGGTAAGGCTGA
TTTTGACACTATGGCGCGTAGTAATGTACAGCAAATGCAAAGCGCCTATCTACAAGCCACAGTGCCTTTAAGCCATACCT
TAAGCTACGTTGTGGGTGGTCGTTATGCGCGGGTGACCGACGAGTTAGTCGATGGTAATGTCTATCCTAATGGCATGGAT
TTAGACGAAAATGCCCACGCATTTGAACTGGGTTTAAATTACCGTCCAACTGCTGAGCACAGACTTTATGTTCGCGCTGA
TGATAACTTCCGTTTTGCGAAAGTGGATGAGCAAGCTTATACATCGCCTGGTGTACTTGGCTTAAAGCCGCAGACGGGTC
GCTCCTATGAAGCGGGTTGGGATTGGACTCTTGCTAGCCAAACTCTACGAGTGAGCCTATACCGTCTCGATTTAGAAGAT
GAAATTGTGTATGACTCAAGCGCCACTAAACCTATTGGTGGTAATTTCGATGGCGCAAATGTCAATGCTGACGCTTCACG
TCGTTATGGCGCAAGTGCCGATTGGGATTGGCAGGTGACTAAAGCAGTACAACTAGGGCTTGAGTATAACTATATCGATG
CCGAATTTACCGACGGTAACAATGATGGCAAGGAGCTGTCTTGGGTGGCAAAACACACGGGGCGCGGATATGTCAGTATG
GATTTTGCTGAGCATTTCCAAGTCTTTGCCGAAGCTATCTACACGGGTGATCACTTTGTAGAAGGTGATAACGGTAATGA
AGGCGATAAGCTGGCTAGTTACGTGCTCGGTAATTTAGCCTTGAACTACAACCGTGATGCTTGGCTTGCCAGCCTGCGTA
TCGATAACCTATTTGATAAAGACTATGTCAGCGCAGGCTATTACGGTGGCCTTTGGGGTGATAGTTATTACTCTGGTCGA
GGCCGCGATATTCGTTTAACCCTCGGCTACCGCTTCTAG

Upstream 100 bases:

>100_bases
GGCAGATCTCAAAATGCGATAGTCACTGTCAGTATCTTTTACTGAATGAACAGTATCGTGGCGCTAATGCCCCGTTTTCC
TTGCAGGAGTTAAAGGTAAA

Downstream 100 bases:

>100_bases
GTATTGATTCGCCAGCAATCGATAAAGCCAGACTTAGTCTGGCTTTATATTTTTTAGGCTTGGTTCAAGGAATAAATTTT
GAAATAGGTATAGTCTTGAA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MGTNPTKIALLIGSLCSFSVIAPAMAADDTSTAKVNEHLVVIGRSDNTPLNIAANVNVIDAAAIEMSGATSVTEVLRGQS
GIQISDNNIGTSFAMRGFSASTAVNNTLILLDGRRLNNIDIAAPSLNAIPLNQVERIEILSGSAGVLYGDQAVGGVINIV
TKSPENTGGSVQLSGGSFDTYEGRGDVSGAINKDWRYFFTGSYNQGDNYRKHNANETGSILGRIQYKTATDSFFVETSYY
DNDRENPGSLTEKQFKDNPRYSGNDKQYSHEMTTAARTGYQHQLNPNWALAADLDYSDTLVSSLNWGQSRNTRSLLMFSP
KALANYSTRQGELNLVTGLDISRGKADFDTMARSNVQQMQSAYLQATVPLSHTLSYVVGGRYARVTDELVDGNVYPNGMD
LDENAHAFELGLNYRPTAEHRLYVRADDNFRFAKVDEQAYTSPGVLGLKPQTGRSYEAGWDWTLASQTLRVSLYRLDLED
EIVYDSSATKPIGGNFDGANVNADASRRYGASADWDWQVTKAVQLGLEYNYIDAEFTDGNNDGKELSWVAKHTGRGYVSM
DFAEHFQVFAEAIYTGDHFVEGDNGNEGDKLASYVLGNLALNYNRDAWLASLRIDNLFDKDYVSAGYYGGLWGDSYYSGR
GRDIRLTLGYRF

Sequences:

>Translated_652_residues
MGTNPTKIALLIGSLCSFSVIAPAMAADDTSTAKVNEHLVVIGRSDNTPLNIAANVNVIDAAAIEMSGATSVTEVLRGQS
GIQISDNNIGTSFAMRGFSASTAVNNTLILLDGRRLNNIDIAAPSLNAIPLNQVERIEILSGSAGVLYGDQAVGGVINIV
TKSPENTGGSVQLSGGSFDTYEGRGDVSGAINKDWRYFFTGSYNQGDNYRKHNANETGSILGRIQYKTATDSFFVETSYY
DNDRENPGSLTEKQFKDNPRYSGNDKQYSHEMTTAARTGYQHQLNPNWALAADLDYSDTLVSSLNWGQSRNTRSLLMFSP
KALANYSTRQGELNLVTGLDISRGKADFDTMARSNVQQMQSAYLQATVPLSHTLSYVVGGRYARVTDELVDGNVYPNGMD
LDENAHAFELGLNYRPTAEHRLYVRADDNFRFAKVDEQAYTSPGVLGLKPQTGRSYEAGWDWTLASQTLRVSLYRLDLED
EIVYDSSATKPIGGNFDGANVNADASRRYGASADWDWQVTKAVQLGLEYNYIDAEFTDGNNDGKELSWVAKHTGRGYVSM
DFAEHFQVFAEAIYTGDHFVEGDNGNEGDKLASYVLGNLALNYNRDAWLASLRIDNLFDKDYVSAGYYGGLWGDSYYSGR
GRDIRLTLGYRF
>Mature_651_residues
GTNPTKIALLIGSLCSFSVIAPAMAADDTSTAKVNEHLVVIGRSDNTPLNIAANVNVIDAAAIEMSGATSVTEVLRGQSG
IQISDNNIGTSFAMRGFSASTAVNNTLILLDGRRLNNIDIAAPSLNAIPLNQVERIEILSGSAGVLYGDQAVGGVINIVT
KSPENTGGSVQLSGGSFDTYEGRGDVSGAINKDWRYFFTGSYNQGDNYRKHNANETGSILGRIQYKTATDSFFVETSYYD
NDRENPGSLTEKQFKDNPRYSGNDKQYSHEMTTAARTGYQHQLNPNWALAADLDYSDTLVSSLNWGQSRNTRSLLMFSPK
ALANYSTRQGELNLVTGLDISRGKADFDTMARSNVQQMQSAYLQATVPLSHTLSYVVGGRYARVTDELVDGNVYPNGMDL
DENAHAFELGLNYRPTAEHRLYVRADDNFRFAKVDEQAYTSPGVLGLKPQTGRSYEAGWDWTLASQTLRVSLYRLDLEDE
IVYDSSATKPIGGNFDGANVNADASRRYGASADWDWQVTKAVQLGLEYNYIDAEFTDGNNDGKELSWVAKHTGRGYVSMD
FAEHFQVFAEAIYTGDHFVEGDNGNEGDKLASYVLGNLALNYNRDAWLASLRIDNLFDKDYVSAGYYGGLWGDSYYSGRG
RDIRLTLGYRF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787723, Length=730, Percent_Identity=24.5205479452055, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788478, Length=157, Percent_Identity=34.3949044585987, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790405, Length=155, Percent_Identity=32.258064516129, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790743, Length=669, Percent_Identity=20.9267563527653, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 71534; Mature: 71403

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTNPTKIALLIGSLCSFSVIAPAMAADDTSTAKVNEHLVVIGRSDNTPLNIAANVNVID
CCCCHHEHHHHHHHHHHHHHHCCHHCCCCCCCEEECCEEEEEECCCCCCEEEEECCEEEE
AAAIEMSGATSVTEVLRGQSGIQISDNNIGTSFAMRGFSASTAVNNTLILLDGRRLNNID
EEEEEECCCHHHHHHHCCCCCCEEECCCCCCHHEECCCCCCCCCCCEEEEEECCEECCEE
IAAPSLNAIPLNQVERIEILSGSAGVLYGDQAVGGVINIVTKSPENTGGSVQLSGGSFDT
EECCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEEEECCCCCCCCEEEECCCCEEC
YEGRGDVSGAINKDWRYFFTGSYNQGDNYRKHNANETGSILGRIQYKTATDSFFVETSYY
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEC
DNDRENPGSLTEKQFKDNPRYSGNDKQYSHEMTTAARTGYQHQLNPNWALAADLDYSDTL
CCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCEEEEECCCCHHHH
VSSLNWGQSRNTRSLLMFSPKALANYSTRQGELNLVTGLDISRGKADFDTMARSNVQQMQ
HHHCCCCCCCCCCEEEEECCHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
SAYLQATVPLSHTLSYVVGGRYARVTDELVDGNVYPNGMDLDENAHAFELGLNYRPTAEH
HHHEEEECCHHHHHHHHHCCEEEEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
RLYVRADDNFRFAKVDEQAYTSPGVLGLKPQTGRSYEAGWDWTLASQTLRVSLYRLDLED
EEEEEECCCEEEEEECHHHCCCCCEEECCCCCCCCCCCCCCEEECCCEEEEEEEEECCCC
EIVYDSSATKPIGGNFDGANVNADASRRYGASADWDWQVTKAVQLGLEYNYIDAEFTDGN
EEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEEEEEEEECEEEEEEEEEECCCC
NDGKELSWVAKHTGRGYVSMDFAEHFQVFAEAIYTGDHFVEGDNGNEGDKLASYVLGNLA
CCCCEEEEEEHHCCCCEEEECHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHEE
LNYNRDAWLASLRIDNLFDKDYVSAGYYGGLWGDSYYSGRGRDIRLTLGYRF
EECCCCEEEEEEEECCCCCCHHHCCCCCCCCCCCCEECCCCCEEEEEEEECC
>Mature Secondary Structure 
GTNPTKIALLIGSLCSFSVIAPAMAADDTSTAKVNEHLVVIGRSDNTPLNIAANVNVID
CCCHHEHHHHHHHHHHHHHHCCHHCCCCCCCEEECCEEEEEECCCCCCEEEEECCEEEE
AAAIEMSGATSVTEVLRGQSGIQISDNNIGTSFAMRGFSASTAVNNTLILLDGRRLNNID
EEEEEECCCHHHHHHHCCCCCCEEECCCCCCHHEECCCCCCCCCCCEEEEEECCEECCEE
IAAPSLNAIPLNQVERIEILSGSAGVLYGDQAVGGVINIVTKSPENTGGSVQLSGGSFDT
EECCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCEEEEEECCCCCCCCEEEECCCCEEC
YEGRGDVSGAINKDWRYFFTGSYNQGDNYRKHNANETGSILGRIQYKTATDSFFVETSYY
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEC
DNDRENPGSLTEKQFKDNPRYSGNDKQYSHEMTTAARTGYQHQLNPNWALAADLDYSDTL
CCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCEEEEECCCCHHHH
VSSLNWGQSRNTRSLLMFSPKALANYSTRQGELNLVTGLDISRGKADFDTMARSNVQQMQ
HHHCCCCCCCCCCEEEEECCHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
SAYLQATVPLSHTLSYVVGGRYARVTDELVDGNVYPNGMDLDENAHAFELGLNYRPTAEH
HHHEEEECCHHHHHHHHHCCEEEEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
RLYVRADDNFRFAKVDEQAYTSPGVLGLKPQTGRSYEAGWDWTLASQTLRVSLYRLDLED
EEEEEECCCEEEEEECHHHCCCCCEEECCCCCCCCCCCCCCEEECCCEEEEEEEEECCCC
EIVYDSSATKPIGGNFDGANVNADASRRYGASADWDWQVTKAVQLGLEYNYIDAEFTDGN
EEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEEEEEEEEECEEEEEEEEEECCCC
NDGKELSWVAKHTGRGYVSMDFAEHFQVFAEAIYTGDHFVEGDNGNEGDKLASYVLGNLA
CCCCEEEEEEHHCCCCEEEECHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHEE
LNYNRDAWLASLRIDNLFDKDYVSAGYYGGLWGDSYYSGRGRDIRLTLGYRF
EECCCCEEEEEEEECCCCCCHHHCCCCCCCCCCCCEECCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA