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The map label for this gene is opdE [H]

Identifier: 126172881

GI number: 126172881

Start: 718191

End: 719423

Strand: Direct

Name: opdE [H]

Synonym: Sbal_0632

Alternate gene names: 126172881

Gene position: 718191-719423 (Clockwise)

Preceding gene: 126172879

Following gene: 126172882

Centisome position: 14.01

GC content: 50.36

Gene sequence:

>1233_bases
ATGACCACTCAGGTATGCGAAACGTCAGAACCACGCTGTGCGATTCAACAAGCAAGTCAACAACAAACGGCAAATTGGAG
TGGCGTGCTGGCGATGTCGTTATGCGTGTTTGCCTTGGTCGCCTCGGAATTTATGCCTGTTAGTTTACTGACACCGATTG
CCGCTGATTTGAATGTGAGTGAAGGATTGGTCGGGCAGGGCATTGCGATATCTGGTTTTTTTGCCGTGTTAACCAGTTTG
AGTATCGCATCAATTGCTAAAGTTACGGATCGTAAGTCACTCCTACTTGGGCTCACTTCGTTAATGTTGGTATCGGGCAT
TGTGATTGCTTATGCCCCTAACTACGCAGTTTATATGCTGGGCCGCTCTTTAATTGGCGTCGTGATTGGTGGATTTTGGT
CTTTGTCTGGCGCGTCGGCGATCCGTCTGGTGCCAACGGAAAAGATCCCTAAAGCCTTGGCGATATTCAATGGTGGCAAC
GCGCTCGCTATGGTAATTGCTGCGCCGCTGGGCAGTTACCTTGGCGCGCATATCGGTTGGCGAGGCGCCTTTTTCGGTTT
AGTGCCCGTTGCACTGATCGCGTTTGTGTGGATGTGGTTTAGTTTGCCCGCGATGAAACCCGAAAAACGCGTTGCTGGCT
CTGCGAATGTGTTTTCTCTATTAAACAAGCCGTTGGTTCGATTGGGAATGTTGGCGATTGTGTTGTTCTTTATGGGGCAG
TTTTCACTGTTTACCTATGTGCGTCCGTTTCTGGAAACCGCTATCCACGTAGAGAGCAATAACTTGTCGTTCATTCTGCT
GGTGATGGGCGTCGCGGGTTTTATGGGGACGCTGCTAGTCAGTGTGTTTTTGAAAAACAATCTCTACCGCACGTTAATCT
TTATTCCGTTGGTGATGGCGGTAATTGCTTTAGCGTTAATCCTGTTTAGCGATAGCAGTGTTGCCGTAACGACGCTGCTT
GCATTGTGGGGCGGCGTTGCCACTGCGGCGCCCGTTGCATGGTGGACTTGGCTTGCGCGAACTATGCCGGAAGACTCTGA
GGTCGGTGGCGGCTTAATGGTGGCGGTTATCCAATTGGCTATCGGGCTGGGCTCAACCTTAGGCGGTGTTCTATTTGATT
TTAATGGTTACCACAGCACATTTATGCTGAGTGCAACCTTGCTAGCGGCGGCTGCTTTACTCGCGTATTGGACCCAACGT
TCAACGCCAGAACCGCTGCTTCACGCTCAATAA

Upstream 100 bases:

>100_bases
GCTCTATAAGCATTCATTAGCTAGTAAGGTTCCAGTGCATTTGAAACAATAGCGACTACAAAGTCAATCAGATTTAAATT
TAACCATTGATAGGTATGTA

Downstream 100 bases:

>100_bases
TGAAGGAATTTTACTATGAAGATTAAAGCTTTTGGTGCAAATGCCAGCCATTTACCGCTGGAACCTATGACGATTACGCG
ACGCCTACCCGGCGAGGATG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTTQVCETSEPRCAIQQASQQQTANWSGVLAMSLCVFALVASEFMPVSLLTPIAADLNVSEGLVGQGIAISGFFAVLTSL
SIASIAKVTDRKSLLLGLTSLMLVSGIVIAYAPNYAVYMLGRSLIGVVIGGFWSLSGASAIRLVPTEKIPKALAIFNGGN
ALAMVIAAPLGSYLGAHIGWRGAFFGLVPVALIAFVWMWFSLPAMKPEKRVAGSANVFSLLNKPLVRLGMLAIVLFFMGQ
FSLFTYVRPFLETAIHVESNNLSFILLVMGVAGFMGTLLVSVFLKNNLYRTLIFIPLVMAVIALALILFSDSSVAVTTLL
ALWGGVATAAPVAWWTWLARTMPEDSEVGGGLMVAVIQLAIGLGSTLGGVLFDFNGYHSTFMLSATLLAAAALLAYWTQR
STPEPLLHAQ

Sequences:

>Translated_410_residues
MTTQVCETSEPRCAIQQASQQQTANWSGVLAMSLCVFALVASEFMPVSLLTPIAADLNVSEGLVGQGIAISGFFAVLTSL
SIASIAKVTDRKSLLLGLTSLMLVSGIVIAYAPNYAVYMLGRSLIGVVIGGFWSLSGASAIRLVPTEKIPKALAIFNGGN
ALAMVIAAPLGSYLGAHIGWRGAFFGLVPVALIAFVWMWFSLPAMKPEKRVAGSANVFSLLNKPLVRLGMLAIVLFFMGQ
FSLFTYVRPFLETAIHVESNNLSFILLVMGVAGFMGTLLVSVFLKNNLYRTLIFIPLVMAVIALALILFSDSSVAVTTLL
ALWGGVATAAPVAWWTWLARTMPEDSEVGGGLMVAVIQLAIGLGSTLGGVLFDFNGYHSTFMLSATLLAAAALLAYWTQR
STPEPLLHAQ
>Mature_409_residues
TTQVCETSEPRCAIQQASQQQTANWSGVLAMSLCVFALVASEFMPVSLLTPIAADLNVSEGLVGQGIAISGFFAVLTSLS
IASIAKVTDRKSLLLGLTSLMLVSGIVIAYAPNYAVYMLGRSLIGVVIGGFWSLSGASAIRLVPTEKIPKALAIFNGGNA
LAMVIAAPLGSYLGAHIGWRGAFFGLVPVALIAFVWMWFSLPAMKPEKRVAGSANVFSLLNKPLVRLGMLAIVLFFMGQF
SLFTYVRPFLETAIHVESNNLSFILLVMGVAGFMGTLLVSVFLKNNLYRTLIFIPLVMAVIALALILFSDSSVAVTTLLA
LWGGVATAAPVAWWTWLARTMPEDSEVGGGLMVAVIQLAIGLGSTLGGVLFDFNGYHSTFMLSATLLAAAALLAYWTQRS
TPEPLLHAQ

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=370, Percent_Identity=39.1891891891892, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1787947, Length=306, Percent_Identity=28.1045751633987, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787808, Length=236, Percent_Identity=27.9661016949153, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786595, Length=392, Percent_Identity=23.9795918367347, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43534; Mature: 43403

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TTQVCETSEPRCAIQQASQQQTANWSGVLAMSLCVFALVASEFMPVSLLTPIAADLNVS
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EGLVGQGIAISGFFAVLTSLSIASIAKVTDRKSLLLGLTSLMLVSGIVIAYAPNYAVYML
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHH
GRSLIGVVIGGFWSLSGASAIRLVPTEKIPKALAIFNGGNALAMVIAAPLGSYLGAHIGW
HHHHHHHHHHHHHHCCCCCEEEECCCHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCH
RGAFFGLVPVALIAFVWMWFSLPAMKPEKRVAGSANVFSLLNKPLVRLGMLAIVLFFMGQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FSLFTYVRPFLETAIHVESNNLSFILLVMGVAGFMGTLLVSVFLKNNLYRTLIFIPLVMA
HHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VIALALILFSDSSVAVTTLLALWGGVATAAPVAWWTWLARTMPEDSEVGGGLMVAVIQLA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IGLGSTLGGVLFDFNGYHSTFMLSATLLAAAALLAYWTQRSTPEPLLHAQ
HHCCHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]