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The map label for this gene is aer [H]

Identifier: 126172792

GI number: 126172792

Start: 612868

End: 614442

Strand: Direct

Name: aer [H]

Synonym: Sbal_0543

Alternate gene names: 126172792

Gene position: 612868-614442 (Clockwise)

Preceding gene: 126172790

Following gene: 126172794

Centisome position: 11.95

GC content: 48.13

Gene sequence:

>1575_bases
ATGAGAACTAATCTACCAGTTACACAGCGAGAATATGATTATCCAGCGGATTGGATTTTATTGTCGACCACGGATACTCA
AAGTCATATTACCTACGCTAACCAATCCTTTTGTACCGTTGCCGGTTTTGAACTCGATGCCATGTTAGGCAAGCCTCACA
ACATGGTGCGTCATCCAGATATGCCTCCCCATGCGTTTGAAGATATGTGGCGCTGCATCAAAAAAGGCGAGCCTTGGAAA
GGGATAGTGAAAAATCGCTGCGCCAATGGCGATCACTATTGGGTTGATGCCTATGTCTCACCCATTTCAGTTAATGGCAA
AGTCGTCGAGTTTCAATCTGTACGCACTAAACCCACCCGCGAGCAGGTTAAGCGTGCAGAAACGGCTTATGCAGAGTTGA
ACAAAAAGGGCAGTGTCAGCGCGTTAAAACGTACAGTGAGCATGCCCGCCAAATTGCTATTACTAGCCCTACTTGCCATG
CTGCCGATGCTTTACCTTGCTCTGCAAATTGGCTTAATGGGCTTTATTGCCCTAGCGATAAGCATCTTAGTGTTGCTGGT
GGGCGGTAATCTGGTGCTGAGTCGTTATTACGCGATAGTGGCTAAGGCAAAGCATATCTACGATAACCCCTTGATGGCGC
ATATTTACAGTGGAAGCAGTGATGATCTTGGCGCGATTGATTTGGCGCTCCAAATGCAGACCTCTGAGCTTAAGTCGATT
CTGGGGCGTGCATCGGATTCCTGTTATAACGTGTCTGAACAGGCCAAAATATCTGCCGCAAAGGGCAAACAAATTCAGAG
TACCAGTCAGGCTCAATTGTCTGAAATAGAGCAAGTTGCTACGGCGATGCAGGAGATGACCGCCACATTAGGTGATATGT
CTTCCAATTGTGCCGATGCCGCCAGTGCCACGCAAATGGCATCCGCTGAAACCATCAATGGTGATAAAACGGTGTCGAGC
ACCATTAGCTCGATTCAAGCTATGGCGGAGCAACTGCAACAAACGTCAAAGGTCATTACTGAGTTAGAAGCCTACAGTAA
AGATATCGGCACAGTGCTAGATGTGATTCAGAGTATTGCGGGTCAGACTAATTTACTGGCATTAAATGCCGCGATTGAAG
CGGCGCGTGCAGGTGAGCAAGGCCGTGGCTTTGCCGTTGTTGCTGACGAGGTAAGGGCATTAGCGCAACGTACTCACGAT
GCCACCAAGGAAATCCAAAGTATGATTAACCTGTTGCAGCAGGGGACCAATAAAGCTGTGGTCAGCATGCAGCAAGGCGT
GGTTGCCGCGTCCCAATGTATTTCAACGGCGGATTTAGCAGGCACGGCATTACGTACGATTCGTGAAGCCATTTCGACCA
TTACCGATATGACGCACCATATTGCCAGCGCGGTTGAAGAACAATCGAGTGTGGCAAATGAAATGAATCGCAGCGTGGTG
AATGTGTCGCAATTTACCCATTCTAGCCATCAACTTGGCAGTGAAATGGTCGGCTTGAACGATGAAGTGACTCGCGAGAT
GGATTCACACTCAGTCTTGGTTGATCAATTCTTAAAGCGCAGCTTTAGGGTGTAA

Upstream 100 bases:

>100_bases
AGAAGTAGGTTCAGGAATATAGAGTCAGGGTGATGATGCCTCACGGATGGATAACTCATGGATGAATAACGAAGAATTAA
TCAAAGATCCATAAGGTTTC

Downstream 100 bases:

>100_bases
TCACCTAAAACTTAAGATAACAAAGGCAATAATCTGACTATTGCCTTTTGTTTTTCTGCTCCCTGACTTAATTTCAATTC
TCTAACTAAATTTCTGCTCT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPDMPPHAFEDMWRCIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTREQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAM
LPMLYLALQIGLMGFIALAISILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADAASATQMASAETINGDKTVSS
TISSIQAMAEQLQQTSKVITELEAYSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIQSMINLLQQGTNKAVVSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV

Sequences:

>Translated_524_residues
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPDMPPHAFEDMWRCIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTREQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAM
LPMLYLALQIGLMGFIALAISILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADAASATQMASAETINGDKTVSS
TISSIQAMAEQLQQTSKVITELEAYSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIQSMINLLQQGTNKAVVSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV
>Mature_524_residues
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPDMPPHAFEDMWRCIKKGEPWK
GIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTREQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAM
LPMLYLALQIGLMGFIALAISILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADAASATQMASAETINGDKTVSS
TISSIQAMAEQLQQTSKVITELEAYSKDIGTVLDVIQSIAGQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHD
ATKEIQSMINLLQQGTNKAVVSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=515, Percent_Identity=31.8446601941748, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=29.320987654321, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI2367378, Length=385, Percent_Identity=26.7532467532467, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788195, Length=234, Percent_Identity=35.4700854700855, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788194, Length=261, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56895; Mature: 56895

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCCCC
MPPHAFEDMWRCIKKGEPWKGIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTR
CCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECEEECCCEEEEECCCCCCCHH
EQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAMLPMLYLALQIGLMGFIALAI
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADA
HHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ASATQMASAETINGDKTVSSTISSIQAMAEQLQQTSKVITELEAYSKDIGTVLDVIQSIA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHDATKEIQSMINLLQQGTNKAV
CCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV
HHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTNLPVTQREYDYPADWILLSTTDTQSHITYANQSFCTVAGFELDAMLGKPHNMVRHPD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCCCC
MPPHAFEDMWRCIKKGEPWKGIVKNRCANGDHYWVDAYVSPISVNGKVVEFQSVRTKPTR
CCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECEEECCCEEEEECCCCCCCHH
EQVKRAETAYAELNKKGSVSALKRTVSMPAKLLLLALLAMLPMLYLALQIGLMGFIALAI
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILVLLVGGNLVLSRYYAIVAKAKHIYDNPLMAHIYSGSSDDLGAIDLALQMQTSELKSI
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LGRASDSCYNVSEQAKISAAKGKQIQSTSQAQLSEIEQVATAMQEMTATLGDMSSNCADA
HHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ASATQMASAETINGDKTVSSTISSIQAMAEQLQQTSKVITELEAYSKDIGTVLDVIQSIA
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRTHDATKEIQSMINLLQQGTNKAV
CCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VSMQQGVVAASQCISTADLAGTALRTIREAISTITDMTHHIASAVEEQSSVANEMNRSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVSQFTHSSHQLGSEMVGLNDEVTREMDSHSVLVDQFLKRSFRV
HHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]