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The map label for this gene is ucpA [C]

Identifier: 125625296

GI number: 125625296

Start: 2497834

End: 2498853

Strand: Direct

Name: ucpA [C]

Synonym: llmg_2543

Alternate gene names: 125625296

Gene position: 2497834-2498853 (Clockwise)

Preceding gene: 125625294

Following gene: 125625297

Centisome position: 98.75

GC content: 34.51

Gene sequence:

>1020_bases
ATGTCAAATCAAGAACCAATAGCAAACTACAAATTTAATTATAAAACAACAGCAAATAAAGTTATGAAAAATATTAATCT
TTCAGGAAAAACAATCATCATCACTGGTGGGTATTCTGGTATTGGTTTAGAGATGACCAAACAACTTTCACGTGCTGGAG
TAAAAATTATTATCCCCGCCCGAAGAATGGAGGTAGCCAAGAAAAATTTATCTAAAATAAAAAATATTGACATTCTTCCC
CTTGACCTCACCAATCCAGAAAGTATTCATCAATTTGCCGAAAGTTTTTTGCAAAATAATTCAAAACTAGATATTCTTAT
TAATTCCTCTGGATTAATGTACCTTCCTTTAAAAAGAGATTCCCGAGGAATAGAATATCACTTTGCCACAAACCATCTAG
GCCACTATCAATTAACAATGGAACTTTTACCCGCTTTAAAAAATGCAAAAAACTCAAGAGTTATAAATTTATCCAGTCGT
GCTCAACAAATGACACCATTACTAGAAGATTGGAATTTTGAAAAAATAGAAAACTATAATCCCCAAATAGGCTACCAACA
ATCTAAAACTGCCAACGTTTTATTTTCAATAAAACTAGATGAACTAGGAAAAAAATATGGAATTAGAAGTTTTGCAGTCC
ACCCTGGTATGATTCCAATGACAAATATCGGTCGTCAAAATTCACCTATTACCCCTTGGCTCCGCTACCTAGCCGACTAT
TTTAAATTAATTCATATCCCCGTATTTTTTAATACACTTAAATCCGGCTTTGACCGAAGTAAATATCGCTATTTAAAAAC
AATAGCCCAAGGTGCTGCAACACCTCTATGGACTGCCACAAGCCCCGATTTAGAAGGTAAAGGTGGTCTATATTGTGAAG
ACCTTAATATTTCCAGACTTATGACATCAGAAGAAGTTGATAATTTTGCTGGAGGTCTACGGCCCCACTCAATAAACCCA
GATGCTGCAAATAGACTTTGGCACATCTCAAAAACTATAACAGGTCTGGATTTTGAATAA

Upstream 100 bases:

>100_bases
TCACTTTTAAAGACAAATCGTCCAAAGTTAATTGTAAAAGTTCTTTTTTGTTGTTACACTTGTATCACATAAATATTATA
ACACAAAGGAAAATTTTATT

Downstream 100 bases:

>100_bases
ATTTTTACTAAAGAGCAAAAATGACCTGTCATAAATAGGTCATTTTATGTTTTGTATTATTAGATTAAGACTCATTCTAG
ATACCATTACAGTAATTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGVKIIIPARRMEVAKKNLSKIKNIDILP
LDLTNPESIHQFAESFLQNNSKLDILINSSGLMYLPLKRDSRGIEYHFATNHLGHYQLTMELLPALKNAKNSRVINLSSR
AQQMTPLLEDWNFEKIENYNPQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADY
FKLIHIPVFFNTLKSGFDRSKYRYLKTIAQGAATPLWTATSPDLEGKGGLYCEDLNISRLMTSEEVDNFAGGLRPHSINP
DAANRLWHISKTITGLDFE

Sequences:

>Translated_339_residues
MSNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGVKIIIPARRMEVAKKNLSKIKNIDILP
LDLTNPESIHQFAESFLQNNSKLDILINSSGLMYLPLKRDSRGIEYHFATNHLGHYQLTMELLPALKNAKNSRVINLSSR
AQQMTPLLEDWNFEKIENYNPQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADY
FKLIHIPVFFNTLKSGFDRSKYRYLKTIAQGAATPLWTATSPDLEGKGGLYCEDLNISRLMTSEEVDNFAGGLRPHSINP
DAANRLWHISKTITGLDFE
>Mature_338_residues
SNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGVKIIIPARRMEVAKKNLSKIKNIDILPL
DLTNPESIHQFAESFLQNNSKLDILINSSGLMYLPLKRDSRGIEYHFATNHLGHYQLTMELLPALKNAKNSRVINLSSRA
QQMTPLLEDWNFEKIENYNPQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADYF
KLIHIPVFFNTLKSGFDRSKYRYLKTIAQGAATPLWTATSPDLEGKGGLYCEDLNISRLMTSEEVDNFAGGLRPHSINPD
AANRLWHISKTITGLDFE

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706523, Length=342, Percent_Identity=29.2397660818713, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI10190746, Length=330, Percent_Identity=30, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI186928839, Length=323, Percent_Identity=31.8885448916409, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI166795268, Length=319, Percent_Identity=30.0940438871473, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI225579078, Length=339, Percent_Identity=30.3834808259587, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI193804850, Length=274, Percent_Identity=32.8467153284672, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI146231950, Length=324, Percent_Identity=29.0123456790123, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI19923931, Length=268, Percent_Identity=31.3432835820896, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7706318, Length=143, Percent_Identity=32.8671328671329, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=24.5059288537549, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786701, Length=133, Percent_Identity=34.5864661654135, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17532791, Length=296, Percent_Identity=29.7297297297297, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI193207620, Length=339, Percent_Identity=29.4985250737463, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17532805, Length=297, Percent_Identity=31.986531986532, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71992402, Length=302, Percent_Identity=27.4834437086093, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17505416, Length=289, Percent_Identity=29.4117647058824, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17535059, Length=298, Percent_Identity=26.8456375838926, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17558006, Length=325, Percent_Identity=25.2307692307692, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32565532, Length=229, Percent_Identity=33.6244541484716, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324820, Length=228, Percent_Identity=26.7543859649123, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=136, Percent_Identity=34.5588235294118, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573296, Length=320, Percent_Identity=32.8125, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI22024069, Length=327, Percent_Identity=30.5810397553517, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45554248, Length=277, Percent_Identity=33.9350180505415, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24640117, Length=277, Percent_Identity=33.9350180505415, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24586328, Length=319, Percent_Identity=28.5266457680251, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20129347, Length=320, Percent_Identity=28.75, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI161076371, Length=282, Percent_Identity=30.8510638297872, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24656154, Length=278, Percent_Identity=29.136690647482, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI19922628, Length=278, Percent_Identity=29.136690647482, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI19921754, Length=292, Percent_Identity=30.1369863013699, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24647946, Length=309, Percent_Identity=29.126213592233, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI45553409, Length=293, Percent_Identity=29.6928327645051, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24647948, Length=293, Percent_Identity=29.6928327645051, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24647931, Length=299, Percent_Identity=23.4113712374582, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38344; Mature: 38213

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGVKIIIPA
CCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEECH
RRMEVAKKNLSKIKNIDILPLDLTNPESIHQFAESFLQNNSKLDILINSSGLMYLPLKRD
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCC
SRGIEYHFATNHLGHYQLTMELLPALKNAKNSRVINLSSRAQQMTPLLEDWNFEKIENYN
CCCEEEEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCHHHCCCC
PQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADY
CCCCCCCCCCCEEEEEEEHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
FKLIHIPVFFNTLKSGFDRSKYRYLKTIAQGAATPLWTATSPDLEGKGGLYCEDLNISRL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECCCHHHH
MTSEEVDNFAGGLRPHSINPDAANRLWHISKTITGLDFE
HHHHHHHHHHCCCCCCCCCCCHHHHEEEEHHHCCCCCCC
>Mature Secondary Structure 
SNQEPIANYKFNYKTTANKVMKNINLSGKTIIITGGYSGIGLEMTKQLSRAGVKIIIPA
CCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEECH
RRMEVAKKNLSKIKNIDILPLDLTNPESIHQFAESFLQNNSKLDILINSSGLMYLPLKRD
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCC
SRGIEYHFATNHLGHYQLTMELLPALKNAKNSRVINLSSRAQQMTPLLEDWNFEKIENYN
CCCEEEEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCHHHCCCC
PQIGYQQSKTANVLFSIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRYLADY
CCCCCCCCCCCEEEEEEEHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHH
FKLIHIPVFFNTLKSGFDRSKYRYLKTIAQGAATPLWTATSPDLEGKGGLYCEDLNISRL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECCCHHHH
MTSEEVDNFAGGLRPHSINPDAANRLWHISKTITGLDFE
HHHHHHHHHHCCCCCCCCCCCHHHHEEEEHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]