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The map label for this gene is arcD2 [H]

Identifier: 125625069

GI number: 125625069

Start: 2255443

End: 2256936

Strand: Reverse

Name: arcD2 [H]

Synonym: llmg_2307

Alternate gene names: 125625069

Gene position: 2256936-2255443 (Counterclockwise)

Preceding gene: 125625070

Following gene: 125625068

Centisome position: 89.23

GC content: 38.15

Gene sequence:

>1494_bases
ATGGAAAACAAGAAAACAAAAGGGATTAGCCTTTTTGCACTACTAGCGATTATCATCTCAGGAGCCATTGGTGGTGGAGT
GTTCAACCTTGCCAATGACTTGGCAAGAGGCTCAACTCCTGGGGGAGTCGTGATTTCATGGCTTTTTATTGGTTTTGGAA
TATTAATGTTAGTTTTGAGTTTTAATCGGCTCATTACAATAAAACCTGATCTTTCTGGTGTATCAGATTATGCTCGAGCA
GGTTTTGGGGACTTTGTAGGTTTTTTATCGGGCTGGGGTTACTGGATTTCAGCATGGACAGGAACAATTGGTTTTGCTGT
TTTAATGATGACTTCTGCTGATTATTTCTTTCCTAGTAAATTTGCAAATTCAAACGGTTCACTAACTATTCTGTCAGTAA
TTATTGTGTCAATTATTTCATGGATATTGATGCTTCTAGTTGATCGAGGAGTAGAAACGGCTGCGGCTGTAAATGCAATT
GTGATGATTGCCAAACTGATTCCATTGGTTGTTTTCTCAATTACAGGAATTATCTTATTTAAGGCCAATGTCTTTACTCA
ACATTTTTGGCAAACCTTTACAACGAATTTTGCTGCTGATGGTTCAGTCAAAGATTTTGTTTGGCACGCAATGACTGTAA
GTGGACTTTTAAGTCAAATTAAGGGCTCATTGATGGTAATGGTTTGGGTCTTTGTGGGGATTGAGGGTGCTACGATGATG
GGAAATCGCGCGAAAAAGAAATCAGATACAGCAAAAGCAACAGTTATTGGTTTAGCAGTTTTGCTTGTTATTTATGTACT
TTTGTCACTCCTTCCTTATGGTTATATGGATCAAGCAAGTTTAGCAAATGTCAAAGCCCCTGGTCTTGTTTACATTCTTA
ATGAAATGGTCGGTGGCTGGGGTGGTAGCCTTATGGCAGTCGGTCTAATGATTTCATTATTAGGAGCATGGCTTTCATGG
ACAATGCTACCGGTTGAAGCTACACAACAGTTGGCAGAGCAAAAGCTATTGCCAAGTTGGTTTGGTAAACTCAATAAATA
TCATGCCCCAAGTAATTCATTGTTGATTACTCAGTTGATGATTCAAATCTTTATTATCATTACATATTTTGTTGCAAATG
CTTATAATGTTTTTATTTATATGGCAACAGCTGTAATAATGATTTGCTATGCTTTAGTTGGTGCCTATCTTTTCAAAATT
GGTCTTAAAGAAGCATCAGTAAAAAATATACTGATTGGTTTCTTCACTTTTGCTTTTCAGGCTCTGGCACTCTACCTCTC
AGGCTGGCAATATGTTTGGCTGGCTATGATTCTATATACAATTGGATTTCTTTTGTTCATTGGAGCAAAAAAAGAGAGTC
ATCAATCAATATCAGTCAAAGAATGGTTGGGGATGCTTGTTGTGACAGTACTTGGGGTATTAGCGATTGTGGTCTTGATT
TGTGGGGCCAAAGCGGGAACAGCCTTTGACCTTCGAGGATTACTAGGATTTTAG

Upstream 100 bases:

>100_bases
TAAAACAGTCTCTATATTCAAGAGACTGTTTTATATTTACAGTCAGATTATACGAATTTAATTATAGCGAATTTATAATT
AAATAATAGAAAGTGAGTAA

Downstream 100 bases:

>100_bases
GCATAATTTAATAATGAATCATCTTATAAAGATAATTTTACTGATGTTTTTCTAGGTGAATGGAGGAAATAATTGATGAG
AACTTTTGCAGAAGTGGAAA

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MENKKTKGISLFALLAIIISGAIGGGVFNLANDLARGSTPGGVVISWLFIGFGILMLVLSFNRLITIKPDLSGVSDYARA
GFGDFVGFLSGWGYWISAWTGTIGFAVLMMTSADYFFPSKFANSNGSLTILSVIIVSIISWILMLLVDRGVETAAAVNAI
VMIAKLIPLVVFSITGIILFKANVFTQHFWQTFTTNFAADGSVKDFVWHAMTVSGLLSQIKGSLMVMVWVFVGIEGATMM
GNRAKKKSDTAKATVIGLAVLLVIYVLLSLLPYGYMDQASLANVKAPGLVYILNEMVGGWGGSLMAVGLMISLLGAWLSW
TMLPVEATQQLAEQKLLPSWFGKLNKYHAPSNSLLITQLMIQIFIIITYFVANAYNVFIYMATAVIMICYALVGAYLFKI
GLKEASVKNILIGFFTFAFQALALYLSGWQYVWLAMILYTIGFLLFIGAKKESHQSISVKEWLGMLVVTVLGVLAIVVLI
CGAKAGTAFDLRGLLGF

Sequences:

>Translated_497_residues
MENKKTKGISLFALLAIIISGAIGGGVFNLANDLARGSTPGGVVISWLFIGFGILMLVLSFNRLITIKPDLSGVSDYARA
GFGDFVGFLSGWGYWISAWTGTIGFAVLMMTSADYFFPSKFANSNGSLTILSVIIVSIISWILMLLVDRGVETAAAVNAI
VMIAKLIPLVVFSITGIILFKANVFTQHFWQTFTTNFAADGSVKDFVWHAMTVSGLLSQIKGSLMVMVWVFVGIEGATMM
GNRAKKKSDTAKATVIGLAVLLVIYVLLSLLPYGYMDQASLANVKAPGLVYILNEMVGGWGGSLMAVGLMISLLGAWLSW
TMLPVEATQQLAEQKLLPSWFGKLNKYHAPSNSLLITQLMIQIFIIITYFVANAYNVFIYMATAVIMICYALVGAYLFKI
GLKEASVKNILIGFFTFAFQALALYLSGWQYVWLAMILYTIGFLLFIGAKKESHQSISVKEWLGMLVVTVLGVLAIVVLI
CGAKAGTAFDLRGLLGF
>Mature_497_residues
MENKKTKGISLFALLAIIISGAIGGGVFNLANDLARGSTPGGVVISWLFIGFGILMLVLSFNRLITIKPDLSGVSDYARA
GFGDFVGFLSGWGYWISAWTGTIGFAVLMMTSADYFFPSKFANSNGSLTILSVIIVSIISWILMLLVDRGVETAAAVNAI
VMIAKLIPLVVFSITGIILFKANVFTQHFWQTFTTNFAADGSVKDFVWHAMTVSGLLSQIKGSLMVMVWVFVGIEGATMM
GNRAKKKSDTAKATVIGLAVLLVIYVLLSLLPYGYMDQASLANVKAPGLVYILNEMVGGWGGSLMAVGLMISLLGAWLSW
TMLPVEATQQLAEQKLLPSWFGKLNKYHAPSNSLLITQLMIQIFIIITYFVANAYNVFIYMATAVIMICYALVGAYLFKI
GLKEASVKNILIGFFTFAFQALALYLSGWQYVWLAMILYTIGFLLFIGAKKESHQSISVKEWLGMLVVTVLGVLAIVVLI
CGAKAGTAFDLRGLLGF

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=471, Percent_Identity=32.6963906581741, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI2367353, Length=352, Percent_Identity=29.8295454545455, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790575, Length=367, Percent_Identity=25.3405994550409, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786908, Length=457, Percent_Identity=21.0065645514223, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53898; Mature: 53898

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCHHHHHHHCCC
>Mature Secondary Structure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HCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9696763 [H]