Click here to switch to the map view.

The map label for this gene is ycdW [C]

Identifier: 125625007

GI number: 125625007

Start: 2204357

End: 2205334

Strand: Reverse

Name: ycdW [C]

Synonym: llmg_2242

Alternate gene names: 125625007

Gene position: 2205334-2204357 (Counterclockwise)

Preceding gene: 125625008

Following gene: 125625006

Centisome position: 87.19

GC content: 35.07

Gene sequence:

>978_bases
ATGATAAAAGCAATTGCCTTAGAAAATGTTTGGTTAAATTTTTCAGATGAAACAAAAGCAGCTTTCAAGAAAAATAAAGC
TTATCAGTTTCAATTTAAAAAAGAAGAAGAGCTGACAGAATCAGATTTTCTGGAAACAGAAGTCTTAGTTGGTCTGCCAA
AGCCTGATTTATTAGCAAAATATAAAAATTTAAAATGGCTCCAACTTTTATCAGCTGGAACCAATGGATACACGCAGGGA
GCTGATTTTCCTGAAGATGTAACTTTGACAAATGCAACAGGAACTTATGGACTTACGATTTCTGAGCATTTACTGACAAT
GGCTTTTATTCTCCTAAGAAAATTTGACCTTTATGAAAAACAACAAGAAAAAGAAATCTGGGAAAATATTGGTCAGATTC
AATCTATTTATGGCTCAACAGTGTTGGTTCATGGTTTAGGTGATATTGGAAGTCATTTTGCACAGAAAATTCAAGCTTTG
GGAGGTCATGTCATTGCAGTCAAACGAACTGTTTATGGTGATGAAGAATTTGCTGACGAAGTTTATGCTGAGTCTGACCT
AGACAAAGTTTTACCAAGAGCTGATATTATTGCTTCAAGTGTTCCTGGGACTCATGAAACTTATAAATTATTTAATCAAG
AAAAATTTGATTTAATGAAAGAAAATGCTATTTTCCTAAACGTTGGTCGAGGAACAAATGTTGATTTAGAAGCCTTATGT
GATGCACTTGAGTCAAAAAAAATTGCTGGGGCAGGAATTGACGTGACCGACCCAGAACCATTGCCTAAAGGTCACCGGGC
TTGGCATACAGAAAGACTATTAATCACTCCTCATGCTTCTGGCGGTTATACTCTTCCTGAAACATGGCGTCGCTTTATGA
AAATATTGGAAAAAAATCTCGATGCCTATGCAAATGGGAAGGATTTAACAAATATTGTTGATATGAAAACAGGATATAAA
CGAAATGCTCACAAATAA

Upstream 100 bases:

>100_bases
GGCAAAGTGCTATAATCAAAGAAAGAAGATAAAGAAAACAAGGCTTGACTTTATTTTCTTTAAGTAGTCTTTAAAATTCA
TTTTATACAAAGGAGTCCCG

Downstream 100 bases:

>100_bases
TATTTCAAAATCAAAATTAAGTGGAAAAAATATTGGTATTTATTTTGGAACTTTTGCTCCTCTACATACGGGGCATCAGC
AACAAATCTATAAATGTGCA

Product: hypothetical protein

Products: NADPH; glyoxylate; glycerate [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MIKAIALENVWLNFSDETKAAFKKNKAYQFQFKKEEELTESDFLETEVLVGLPKPDLLAKYKNLKWLQLLSAGTNGYTQG
ADFPEDVTLTNATGTYGLTISEHLLTMAFILLRKFDLYEKQQEKEIWENIGQIQSIYGSTVLVHGLGDIGSHFAQKIQAL
GGHVIAVKRTVYGDEEFADEVYAESDLDKVLPRADIIASSVPGTHETYKLFNQEKFDLMKENAIFLNVGRGTNVDLEALC
DALESKKIAGAGIDVTDPEPLPKGHRAWHTERLLITPHASGGYTLPETWRRFMKILEKNLDAYANGKDLTNIVDMKTGYK
RNAHK

Sequences:

>Translated_325_residues
MIKAIALENVWLNFSDETKAAFKKNKAYQFQFKKEEELTESDFLETEVLVGLPKPDLLAKYKNLKWLQLLSAGTNGYTQG
ADFPEDVTLTNATGTYGLTISEHLLTMAFILLRKFDLYEKQQEKEIWENIGQIQSIYGSTVLVHGLGDIGSHFAQKIQAL
GGHVIAVKRTVYGDEEFADEVYAESDLDKVLPRADIIASSVPGTHETYKLFNQEKFDLMKENAIFLNVGRGTNVDLEALC
DALESKKIAGAGIDVTDPEPLPKGHRAWHTERLLITPHASGGYTLPETWRRFMKILEKNLDAYANGKDLTNIVDMKTGYK
RNAHK
>Mature_325_residues
MIKAIALENVWLNFSDETKAAFKKNKAYQFQFKKEEELTESDFLETEVLVGLPKPDLLAKYKNLKWLQLLSAGTNGYTQG
ADFPEDVTLTNATGTYGLTISEHLLTMAFILLRKFDLYEKQQEKEIWENIGQIQSIYGSTVLVHGLGDIGSHFAQKIQAL
GGHVIAVKRTVYGDEEFADEVYAESDLDKVLPRADIIASSVPGTHETYKLFNQEKFDLMKENAIFLNVGRGTNVDLEALC
DALESKKIAGAGIDVTDPEPLPKGHRAWHTERLLITPHASGGYTLPETWRRFMKILEKNLDAYANGKDLTNIVDMKTGYK
RNAHK

Specific function: Unknown

COG id: COG0111

COG function: function code HE; Phosphoglycerate dehydrogenase and related dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI6912396, Length=145, Percent_Identity=36.551724137931, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87081824, Length=226, Percent_Identity=26.9911504424779, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082289, Length=245, Percent_Identity=28.1632653061224, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789279, Length=294, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787645, Length=201, Percent_Identity=24.8756218905473, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17532191, Length=176, Percent_Identity=31.8181818181818, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320925, Length=303, Percent_Identity=26.4026402640264, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322116, Length=297, Percent_Identity=26.2626262626263, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324964, Length=276, Percent_Identity=24.6376811594203, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324055, Length=125, Percent_Identity=33.6, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28574286, Length=239, Percent_Identity=28.8702928870293, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571528, Length=182, Percent_Identity=32.967032967033, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI45551003, Length=228, Percent_Identity=28.5087719298246, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24585514, Length=228, Percent_Identity=28.5087719298246, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28574282, Length=228, Percent_Identity=28.5087719298246, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45552429, Length=228, Percent_Identity=28.5087719298246, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28574284, Length=228, Percent_Identity=28.5087719298246, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24585516, Length=253, Percent_Identity=29.2490118577075, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921140, Length=228, Percent_Identity=29.3859649122807, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006140
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02826 2-Hacid_dh_C [H]

EC number: NA

Molecular weight: Translated: 36546; Mature: 36546

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAIALENVWLNFSDETKAAFKKNKAYQFQFKKEEELTESDFLETEVLVGLPKPDLLAK
CCEEEEEEEEEECCCCHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHHEEECCCHHHHHH
YKNLKWLQLLSAGTNGYTQGADFPEDVTLTNATGTYGLTISEHLLTMAFILLRKFDLYEK
HCCCHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHH
QQEKEIWENIGQIQSIYGSTVLVHGLGDIGSHFAQKIQALGGHVIAVKRTVYGDEEFADE
HHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHH
VYAESDLDKVLPRADIIASSVPGTHETYKLFNQEKFDLMKENAIFLNVGRGTNVDLEALC
HHHHCCHHHHCCHHHHHHCCCCCCHHHHHHHCHHHHHHHHCCEEEEECCCCCCCCHHHHH
DALESKKIAGAGIDVTDPEPLPKGHRAWHTERLLITPHASGGYTLPETWRRFMKILEKNL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
DAYANGKDLTNIVDMKTGYKRNAHK
HHHCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIKAIALENVWLNFSDETKAAFKKNKAYQFQFKKEEELTESDFLETEVLVGLPKPDLLAK
CCEEEEEEEEEECCCCHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHHEEECCCHHHHHH
YKNLKWLQLLSAGTNGYTQGADFPEDVTLTNATGTYGLTISEHLLTMAFILLRKFDLYEK
HCCCHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHH
QQEKEIWENIGQIQSIYGSTVLVHGLGDIGSHFAQKIQALGGHVIAVKRTVYGDEEFADE
HHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHH
VYAESDLDKVLPRADIIASSVPGTHETYKLFNQEKFDLMKENAIFLNVGRGTNVDLEALC
HHHHCCHHHHCCHHHHHHCCCCCCHHHHHHHCHHHHHHHHCCEEEEECCCCCCCCHHHHH
DALESKKIAGAGIDVTDPEPLPKGHRAWHTERLLITPHASGGYTLPETWRRFMKILEKNL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
DAYANGKDLTNIVDMKTGYKRNAHK
HHHCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glycolate; NADP; hydroxypyruvate; NADPH [C]

Specific reaction: glycolate + NADP = NADPH + glyoxylate hydroxypyruvate + NADPH = glycerate + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]