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The map label for this gene is pgsA [H]

Identifier: 125624991

GI number: 125624991

Start: 2186432

End: 2187004

Strand: Reverse

Name: pgsA [H]

Synonym: llmg_2224

Alternate gene names: 125624991

Gene position: 2187004-2186432 (Counterclockwise)

Preceding gene: 125624992

Following gene: 125624990

Centisome position: 86.46

GC content: 38.39

Gene sequence:

>573_bases
ATGAAACAGAAATTACCTAATCAATTAACGATGGCAAGGATTTTTATGATTCCAATCTTTGTGATTTTATTTTATTTACC
ACAGGGAGCTCATTTTAATGGTTTTGTTTCCCAAGATCACAGCTCAGTAATGTGGGTTGTTGCAGCAATTGTTTTTGCGA
TAGCTTCTTTTACTGACTGGCTTGATGGCTATCTTGCCCGCAAATGGCATGTGGTCAGTAACTTTGGTAAATTTGCGGAC
CCGTTAGCTGATAAAATGCTTAACATGGTTGCCTTTGTTGTCCTTGTTGGATTACATGTTGTTCCAATGTGGGCCGTTGC
CATTATCATTTGCCGTGAACTTGCTGTCACAGGCTTACGTCTATTGCTTGTCGAACAAGGTGGAGTCGTTATGGCGGCAG
CAATGCCTGGCAAAATCAAGACAGCTACACAAATGTTAAGCGTCATCTTCCTTTTCATTGGAAATCCTTTATATATTGGA
ACAATCCTTTTTTATGTCTGTGTTTTCTTTACCATTTATAGTGGTTATGACTACTTTGCTAAAAATATGCAAGTTTTTAG
AAACGCTGACTAA

Upstream 100 bases:

>100_bases
GACCGGCCAAAATTACTCTACAAATTAATCGAACAACAACAAATTCAGCTGCTCAGTAAAGAAAAACTGATGGCTTGTTT
TTGGCTGTAAAAGGAGAACT

Downstream 100 bases:

>100_bases
TTCTTTTAGAAAAAATATGAAAATCCAAGTAGAAATACTTGTATTTTTTATTTAGAGTGCCAGATATGGCACGAATAGAA
GAAGACGAAGGAACAGCTGT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKQKLPNQLTMARIFMIPIFVILFYLPQGAHFNGFVSQDHSSVMWVVAAIVFAIASFTDWLDGYLARKWHVVSNFGKFAD
PLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLRLLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIG
TILFYVCVFFTIYSGYDYFAKNMQVFRNAD

Sequences:

>Translated_190_residues
MKQKLPNQLTMARIFMIPIFVILFYLPQGAHFNGFVSQDHSSVMWVVAAIVFAIASFTDWLDGYLARKWHVVSNFGKFAD
PLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLRLLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIG
TILFYVCVFFTIYSGYDYFAKNMQVFRNAD
>Mature_190_residues
MKQKLPNQLTMARIFMIPIFVILFYLPQGAHFNGFVSQDHSSVMWVVAAIVFAIASFTDWLDGYLARKWHVVSNFGKFAD
PLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLRLLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIG
TILFYVCVFFTIYSGYDYFAKNMQVFRNAD

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=187, Percent_Identity=34.7593582887701, Blast_Score=104, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21331; Mature: 21331

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKLPNQLTMARIFMIPIFVILFYLPQGAHFNGFVSQDHSSVMWVVAAIVFAIASFTDW
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LDGYLARKWHVVSNFGKFADPLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIGTILFYVCVFFTIYSGYDYFA
HEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHH
KNMQVFRNAD
HHHHHHHCCC
>Mature Secondary Structure
MKQKLPNQLTMARIFMIPIFVILFYLPQGAHFNGFVSQDHSSVMWVVAAIVFAIASFTDW
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LDGYLARKWHVVSNFGKFADPLADKMLNMVAFVVLVGLHVVPMWAVAIIICRELAVTGLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVEQGGVVMAAAMPGKIKTATQMLSVIFLFIGNPLYIGTILFYVCVFFTIYSGYDYFA
HEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHH
KNMQVFRNAD
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA