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The map label for this gene is acmB [H]

Identifier: 125624936

GI number: 125624936

Start: 2125886

End: 2127502

Strand: Reverse

Name: acmB [H]

Synonym: llmg_2165

Alternate gene names: 125624936

Gene position: 2127502-2125886 (Counterclockwise)

Preceding gene: 125624937

Following gene: 125624935

Centisome position: 84.11

GC content: 35.56

Gene sequence:

>1617_bases
TTGGTAAATACGCAAGTGAAGCGAGTGAAAAAGCAAAAATTTATTGCAGGGACTGCTCTGCTTTTAGGTATGGCAACATT
TGGTATGGTTGGTAAGGCTGATGACCTTTCTTCTTCAAATACAAATGGTGGAGTAGATAACTCAAAAGTAGATAATGATA
ATCAGGAAAGTGTAAAAACATCTACTGAAGGTGTTTCATCAACGACTGAGAATGCTAATACTGTACCAGAAAGTAAAGTC
ACTTCAACAGTAGATTCTGAAAGTGCGCCTTCTAAGACGATTAGTGCAGGTACTCAATCAAATATTTCAGGGACTAGTGA
TGGTTCTGATTCATTACCAAAAACTGAGACATCTGATTCATCATCAAAACCAAGTACGTCTAATTCATCATCAAAACCAA
GTACGTCTAATTCATCATCAAAACCAAGTACGTCTAATTCATCATCAAATAATAATTCAGCTACTAAACCTTCTACAACG
ACACAAGCGCCTCCAGTAGCACCATCTACGACGGCACCATCAGCAACACCATCTACAACGGCACCTTCTAATTATTATCA
AAATAGCTCTTATAATCAAACGTCAACTGCAGCGCAAATTCCTAATTCTTCATCAGATTCAGCAGCCTCTGTATATAGTG
GGCCTGTATTGAAAAAAATCGAAGCTGCTAAACCAATTGAAAAAATTGATTCTTCTAGCACAGAAGCTTTTATTAAAAGT
ATCGCCGATCGAGTACGAATTTTAGCAGGTAAAAATAATTTATATGCTTCAATTATTTTGGCGCAGGCGATTTTGGAATC
TGGTTCTGGGCAAAGTAATATGACCCAACAATATTTTAATATTTTCAATATTACGGGGGCTTATTTAGGAAAATCAATTT
CATTTAAAACAGAAGAATTTTCTGGGAATAATCCTTATTATATTGAACAAAGTTTTAGAGTTTATAGCAACTATGACCAA
GCTTTAGATGATTATATTAACTTAATGATTAAGGGGACAACTTGGAATTCAGAAATTTATGCTGGTGCTTGGAAATCTCA
TGCGAAAACTTATCAAGAAGCAGCTCAAGCTTTACAAGGTATCTTTGCTACAGACCCTGAATATGCCCAAAAATTGATTG
AAATTATTGAAGAATATAACTTGAATTTTTATGATAATGTCGACAGTACGACTCAAGTTTTAGATAGTAATATTCCAGAA
AGTCCACTTGTCGCTTCAAAATTAGATTCATCAACTTATCCAGATTATAATGGGGTGGAATATCCTGGAGCAGATAGTTA
TGCTTTTGGTAACTGTACTCAATATGTTTATAATCGAATTATTCAGCTTGGTGGACAAATTGGGACTCATATGGGTAATG
GTGGAGAATGGGGTATCAATGCTCAAGCTCAAGGTTACTTTACGACAACTGTTCCTACTGAGGGTTATGCTGTCAGTTTC
CCACCAGGTGTAGCTGGTTCTAGTCCAGAATATGGACATGTAGCTTTTGTTGAGAAAGTTTATCCAGATAATTCTATTTT
AGTTTCTGAAATGAATGTAAAAGGAAATAATATTGTCAGTGAACGCCATATTTCTGCTGGTGTTGCCGCATTAGCAACTT
ATATCCAACCTAAATAA

Upstream 100 bases:

>100_bases
TGACTTGAATGATTAAAAGTGTTACAATTGTGTAAATGTAAACGTCTTGAAGAAATGATGTTGAAATTATACTATTGTAA
GCTATGGAGGATAAAATACA

Downstream 100 bases:

>100_bases
TTAGTAATGATAGAATAAAAAAACATCAAAAATTTAAAATTAGGAATACTTTATCTAATTATAAAAAAGAAGAGATTAAA
AATCAGCCCAAAGGCTGATT

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Autolysin; Lysozyme; Peptidoglycan hydrolase [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MVNTQVKRVKKQKFIAGTALLLGMATFGMVGKADDLSSSNTNGGVDNSKVDNDNQESVKTSTEGVSSTTENANTVPESKV
TSTVDSESAPSKTISAGTQSNISGTSDGSDSLPKTETSDSSSKPSTSNSSSKPSTSNSSSKPSTSNSSSNNNSATKPSTT
TQAPPVAPSTTAPSATPSTTAPSNYYQNSSYNQTSTAAQIPNSSSDSAASVYSGPVLKKIEAAKPIEKIDSSSTEAFIKS
IADRVRILAGKNNLYASIILAQAILESGSGQSNMTQQYFNIFNITGAYLGKSISFKTEEFSGNNPYYIEQSFRVYSNYDQ
ALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFATDPEYAQKLIEIIEEYNLNFYDNVDSTTQVLDSNIPE
SPLVASKLDSSTYPDYNGVEYPGADSYAFGNCTQYVYNRIIQLGGQIGTHMGNGGEWGINAQAQGYFTTTVPTEGYAVSF
PPGVAGSSPEYGHVAFVEKVYPDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK

Sequences:

>Translated_538_residues
MVNTQVKRVKKQKFIAGTALLLGMATFGMVGKADDLSSSNTNGGVDNSKVDNDNQESVKTSTEGVSSTTENANTVPESKV
TSTVDSESAPSKTISAGTQSNISGTSDGSDSLPKTETSDSSSKPSTSNSSSKPSTSNSSSKPSTSNSSSNNNSATKPSTT
TQAPPVAPSTTAPSATPSTTAPSNYYQNSSYNQTSTAAQIPNSSSDSAASVYSGPVLKKIEAAKPIEKIDSSSTEAFIKS
IADRVRILAGKNNLYASIILAQAILESGSGQSNMTQQYFNIFNITGAYLGKSISFKTEEFSGNNPYYIEQSFRVYSNYDQ
ALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFATDPEYAQKLIEIIEEYNLNFYDNVDSTTQVLDSNIPE
SPLVASKLDSSTYPDYNGVEYPGADSYAFGNCTQYVYNRIIQLGGQIGTHMGNGGEWGINAQAQGYFTTTVPTEGYAVSF
PPGVAGSSPEYGHVAFVEKVYPDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK
>Mature_538_residues
MVNTQVKRVKKQKFIAGTALLLGMATFGMVGKADDLSSSNTNGGVDNSKVDNDNQESVKTSTEGVSSTTENANTVPESKV
TSTVDSESAPSKTISAGTQSNISGTSDGSDSLPKTETSDSSSKPSTSNSSSKPSTSNSSSKPSTSNSSSNNNSATKPSTT
TQAPPVAPSTTAPSATPSTTAPSNYYQNSSYNQTSTAAQIPNSSSDSAASVYSGPVLKKIEAAKPIEKIDSSSTEAFIKS
IADRVRILAGKNNLYASIILAQAILESGSGQSNMTQQYFNIFNITGAYLGKSISFKTEEFSGNNPYYIEQSFRVYSNYDQ
ALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFATDPEYAQKLIEIIEEYNLNFYDNVDSTTQVLDSNIPE
SPLVASKLDSSTYPDYNGVEYPGADSYAFGNCTQYVYNRIIQLGGQIGTHMGNGGEWGINAQAQGYFTTTVPTEGYAVSF
PPGVAGSSPEYGHVAFVEKVYPDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK

Specific function: Hydrolyzes the cell wall of L.lactis and M.lysodeikticus. Required for cell separation during growth [H]

COG id: COG1705

COG function: function code NU; Muramidase (flagellum-specific)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=152, Percent_Identity=30.9210526315789, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013338
- InterPro:   IPR002901
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01832 Glucosaminidase; PF01476 LysM [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 57149; Mature: 57149

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNTQVKRVKKQKFIAGTALLLGMATFGMVGKADDLSSSNTNGGVDNSKVDNDNQESVKT
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
STEGVSSTTENANTVPESKVTSTVDSESAPSKTISAGTQSNISGTSDGSDSLPKTETSDS
HHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSKPSTSNSSSKPSTSNSSSKPSTSNSSSNNNSATKPSTTTQAPPVAPSTTAPSATPSTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APSNYYQNSSYNQTSTAAQIPNSSSDSAASVYSGPVLKKIEAAKPIEKIDSSSTEAFIKS
CCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHCCHHHHHHHHHCCHHHHCCCHHHHHHHH
IADRVRILAGKNNLYASIILAQAILESGSGQSNMTQQYFNIFNITGAYLGKSISFKTEEF
HHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCC
SGNNPYYIEQSFRVYSNYDQALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQG
CCCCCEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHH
IFATDPEYAQKLIEIIEEYNLNFYDNVDSTTQVLDSNIPESPLVASKLDSSTYPDYNGVE
HHCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCC
YPGADSYAFGNCTQYVYNRIIQLGGQIGTHMGNGGEWGINAQAQGYFTTTVPTEGYAVSF
CCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEC
PPGVAGSSPEYGHVAFVEKVYPDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK
CCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNTQVKRVKKQKFIAGTALLLGMATFGMVGKADDLSSSNTNGGVDNSKVDNDNQESVKT
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
STEGVSSTTENANTVPESKVTSTVDSESAPSKTISAGTQSNISGTSDGSDSLPKTETSDS
HHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSKPSTSNSSSKPSTSNSSSKPSTSNSSSNNNSATKPSTTTQAPPVAPSTTAPSATPSTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APSNYYQNSSYNQTSTAAQIPNSSSDSAASVYSGPVLKKIEAAKPIEKIDSSSTEAFIKS
CCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHCCHHHHHHHHHCCHHHHCCCHHHHHHHH
IADRVRILAGKNNLYASIILAQAILESGSGQSNMTQQYFNIFNITGAYLGKSISFKTEEF
HHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCC
SGNNPYYIEQSFRVYSNYDQALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQG
CCCCCEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHH
IFATDPEYAQKLIEIIEEYNLNFYDNVDSTTQVLDSNIPESPLVASKLDSSTYPDYNGVE
HHCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCC
YPGADSYAFGNCTQYVYNRIIQLGGQIGTHMGNGGEWGINAQAQGYFTTTVPTEGYAVSF
CCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEC
PPGVAGSSPEYGHVAFVEKVYPDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK
CCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11131071 [H]