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The map label for this gene is sunL [H]

Identifier: 125624853

GI number: 125624853

Start: 2061936

End: 2063210

Strand: Reverse

Name: sunL [H]

Synonym: llmg_2081

Alternate gene names: 125624853

Gene position: 2063210-2061936 (Counterclockwise)

Preceding gene: 125624854

Following gene: 125624852

Centisome position: 81.57

GC content: 35.61

Gene sequence:

>1275_bases
ATGACAAAAAATGCAAGACAAACCGCACTCGATGTACTAAATGATATTTTTGGTAATGATGCCTATGCAAATATTTCATT
GGATCGAAATTTGCGAGATTCTGAACTATCCACAGTGGATAAAGGCTTTGTAACAGCCCTTGTCTACGGTGTAGTTTCTA
AAAAAGCTTTATTAGAGTGGTACATTACCCCTTTATTAAAAAAAGAGCCTAAACCTTGGGCTAAAATGCTTTTATTACTC
ACAATTTATCAAGTCCTATTTATGGATAAGGTGCCTATTTCGGCAGCAGTTGATGAAGCTGTAAAAATTGCTAAACGACA
TGATGGACAAGCAACAGCTAATTTTATTAATGCTGTTTTAAGAAACTTTATGCGTTCTGAGCACAGAAATGAAGAACCTA
AAGATTGGGAAACTAAATATTCAATGCCAAAACTGTTATTGGATAAAATGGTTCGCCAATTCGGTGGGAAAAGAACAGGA
GAAATCCTCGAAAGTCTTGAAAAACCAAGTCATGTGAGCTTACGAAAAATTGATCCAACTGTAGAAATTGCTGGGACTCG
TCCGTCTTTACTGACAGAAACAGCATTAATTGCTGACAGCGGAAATTTTTCAATTACAGAAGAGTTTCAAACTGGAAGAA
TTACGATTCAAGATGAAACAAGTCAATTAGTTGCTCCTCAACTTGAATTAGAAGGAACAGAAGAAGTTCTTGATGCCTGT
GCTGCCCCAGGTGGGAAAAGCACACATATGGCTCAATATTTGACAACAGGTCATATCACGGCATTGGATTTATACGAGCA
TAAACTTGATTTAATTAATCAAAATGCACAACGTCAGCATGTTGCGGATAAAATTACCACTCAAAAAGCTGATGCGACAA
TGATTTATGAGAATTTTGGTCCAGAAAAATTTGATCGAATTCTAGTCGATGCTCCATGTTCAGGAATTGGATTAATTCGC
CGTAAACCAGATATCCGTTACCGGAAAGAAAGTTCGGATTTCATAGATTTACAAAAAATTCAATTAGAAATTCTAAACAG
CGCCTCGAAAAGCCTGAAAAAAAGTGGTATAATGGTGTACAGTACTTGTACAATTTTTGATGAAGAAAACTTTGACGTTG
TTCATGAGTTCCTTGAAAATCATCCAAATTTTGAACAAGTTGAAATTTCAAATGAAAAACCAGAAGTGATTAAAGAGGGC
TGTCTTTTCATTACCCCTGAAATGTATCATACGGATGGATTCTTCATCGCGAAATTTAAAAAAATAGGTGAATAA

Upstream 100 bases:

>100_bases
TCATAGGTATTCATTAGTACAATAATTTGCATATATCCCCTAAAACAAGGTTTAGCGGTATCTATTGACATTTATTGACA
CAGTATGTCATAATAGCTCT

Downstream 100 bases:

>100_bases
TTTACTGACGAATATTCTGTTTTGAGAATTTGAGAAAGAATCATTTTTTCTCGAAAATTTTTAAACTCTATCAGTAATTT
TTAGACCTAAAAATAAAACT

Product: ribosomal RNA small subunit methyltransferase B

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKGFVTALVYGVVSKKALLEWYITPLLKKEPKPWAKMLLLL
TIYQVLFMDKVPISAAVDEAVKIAKRHDGQATANFINAVLRNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTG
EILESLEKPSHVSLRKIDPTVEIAGTRPSLLTETALIADSGNFSITEEFQTGRITIQDETSQLVAPQLELEGTEEVLDAC
AAPGGKSTHMAQYLTTGHITALDLYEHKLDLINQNAQRQHVADKITTQKADATMIYENFGPEKFDRILVDAPCSGIGLIR
RKPDIRYRKESSDFIDLQKIQLEILNSASKSLKKSGIMVYSTCTIFDEENFDVVHEFLENHPNFEQVEISNEKPEVIKEG
CLFITPEMYHTDGFFIAKFKKIGE

Sequences:

>Translated_424_residues
MTKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKGFVTALVYGVVSKKALLEWYITPLLKKEPKPWAKMLLLL
TIYQVLFMDKVPISAAVDEAVKIAKRHDGQATANFINAVLRNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTG
EILESLEKPSHVSLRKIDPTVEIAGTRPSLLTETALIADSGNFSITEEFQTGRITIQDETSQLVAPQLELEGTEEVLDAC
AAPGGKSTHMAQYLTTGHITALDLYEHKLDLINQNAQRQHVADKITTQKADATMIYENFGPEKFDRILVDAPCSGIGLIR
RKPDIRYRKESSDFIDLQKIQLEILNSASKSLKKSGIMVYSTCTIFDEENFDVVHEFLENHPNFEQVEISNEKPEVIKEG
CLFITPEMYHTDGFFIAKFKKIGE
>Mature_423_residues
TKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKGFVTALVYGVVSKKALLEWYITPLLKKEPKPWAKMLLLLT
IYQVLFMDKVPISAAVDEAVKIAKRHDGQATANFINAVLRNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTGE
ILESLEKPSHVSLRKIDPTVEIAGTRPSLLTETALIADSGNFSITEEFQTGRITIQDETSQLVAPQLELEGTEEVLDACA
APGGKSTHMAQYLTTGHITALDLYEHKLDLINQNAQRQHVADKITTQKADATMIYENFGPEKFDRILVDAPCSGIGLIRR
KPDIRYRKESSDFIDLQKIQLEILNSASKSLKKSGIMVYSTCTIFDEENFDVVHEFLENHPNFEQVEISNEKPEVIKEGC
LFITPEMYHTDGFFIAKFKKIGE

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=351, Percent_Identity=30.7692307692308, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI76150623, Length=351, Percent_Identity=30.7692307692308, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI32698918, Length=196, Percent_Identity=35.2040816326531, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI11545785, Length=195, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI39995082, Length=208, Percent_Identity=28.8461538461538, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI301336155, Length=208, Percent_Identity=28.8461538461538, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI2367212, Length=404, Percent_Identity=29.4554455445545, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI87081985, Length=224, Percent_Identity=30.8035714285714, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=324, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71998419, Length=225, Percent_Identity=30.2222222222222, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115534021, Length=225, Percent_Identity=30.2222222222222, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25143471, Length=270, Percent_Identity=28.5185185185185, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324268, Length=235, Percent_Identity=32.3404255319149, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319447, Length=289, Percent_Identity=25.2595155709343, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324306, Length=291, Percent_Identity=24.3986254295533, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI22024126, Length=241, Percent_Identity=29.4605809128631, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24668781, Length=235, Percent_Identity=30.6382978723404, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356513, Length=235, Percent_Identity=30.6382978723404, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355201, Length=200, Percent_Identity=29, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356579, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920494, Length=194, Percent_Identity=28.3505154639175, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 47950; Mature: 47819

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKGFVTALVYGVVSKKALLEW
CCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YITPLLKKEPKPWAKMLLLLTIYQVLFMDKVPISAAVDEAVKIAKRHDGQATANFINAVL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTGEILESLEKPSHVSLRKIDPT
HHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCC
VEIAGTRPSLLTETALIADSGNFSITEEFQTGRITIQDETSQLVAPQLELEGTEEVLDAC
EEECCCCCHHHHHHEEEECCCCCEEEEECCCCEEEEECCCCHHHCCCCCCCCHHHHHHHH
AAPGGKSTHMAQYLTTGHITALDLYEHKLDLINQNAQRQHVADKITTQKADATMIYENFG
CCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCC
PEKFDRILVDAPCSGIGLIRRKPDIRYRKESSDFIDLQKIQLEILNSASKSLKKSGIMVY
HHHHHHEEEECCCCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE
STCTIFDEENFDVVHEFLENHPNFEQVEISNEKPEVIKEGCLFITPEMYHTDGFFIAKFK
EEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCEEECCCEEECCCEEEEHHH
KIGE
HHCC
>Mature Secondary Structure 
TKNARQTALDVLNDIFGNDAYANISLDRNLRDSELSTVDKGFVTALVYGVVSKKALLEW
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YITPLLKKEPKPWAKMLLLLTIYQVLFMDKVPISAAVDEAVKIAKRHDGQATANFINAVL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RNFMRSEHRNEEPKDWETKYSMPKLLLDKMVRQFGGKRTGEILESLEKPSHVSLRKIDPT
HHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCC
VEIAGTRPSLLTETALIADSGNFSITEEFQTGRITIQDETSQLVAPQLELEGTEEVLDAC
EEECCCCCHHHHHHEEEECCCCCEEEEECCCCEEEEECCCCHHHCCCCCCCCHHHHHHHH
AAPGGKSTHMAQYLTTGHITALDLYEHKLDLINQNAQRQHVADKITTQKADATMIYENFG
CCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCC
PEKFDRILVDAPCSGIGLIRRKPDIRYRKESSDFIDLQKIQLEILNSASKSLKKSGIMVY
HHHHHHEEEECCCCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE
STCTIFDEENFDVVHEFLENHPNFEQVEISNEKPEVIKEGCLFITPEMYHTDGFFIAKFK
EEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCEEECCCEEECCCEEEEHHH
KIGE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]