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The map label for this gene is cysS [H]

Identifier: 125624812

GI number: 125624812

Start: 2022571

End: 2023917

Strand: Reverse

Name: cysS [H]

Synonym: llmg_2040

Alternate gene names: 125624812

Gene position: 2023917-2022571 (Counterclockwise)

Preceding gene: 125624813

Following gene: 125624811

Centisome position: 80.01

GC content: 36.3

Gene sequence:

>1347_bases
ATGAAAATATATAACACTTATAGTCGACAGTTAGAAGATTTTCAACCGATTGAACCTGGAAAAGTTAAAATGTATGTCTG
CGGACCGACCGTTTATAATTACATCCATGTGGGAAATGCTCGCTCAGTTGTTGCTTTTGATTTAGTCAGAAAATATTTGG
AATTTCGGGGATTTGAAGTTGAATATATCTCTAATTTCACAGATGTTGATGATAAAATTATTAAGGCAGCTGCCAGTGAA
AATATCAGTACAAAAGAACTTTCAGAACGCTATATTGCGGCATTCTATGAAGACACTGATTTATTGAATGTCAAAAGAGC
CAGCCAAAATCCAAAAGCAACGGAATTTATCGAAGCGATGATTGATTTTATTCAAGAACTTTTGGATAAGGACTACGCTT
ATATTTCTGAGGGTGATGTGTATTTCCGTGTAGCTAAATCAAAAGATTACGCTAAATTGGCAAATAAAAACCTTGCAGAT
TTACTTGCAGGTGCATCTGGACGTACGGATGAGGAAACTAATTTAAAAGAATCACCAGCCGATTTCGCCCTTTGGAAATC
TGTAAAAGCTGATGAAGTTTCGTGGCAAGCCCCTTGGGGAGCAGGACGTCCGGGTTGGCATATTGAATGTTCTGTCATGT
CAACTTCATTATTGGGTGAAACGATTGATATTCATGGAGGGGGAGCAGATTTAGAATTTCCTCACCATACTAATGAAATT
GCACAATCTGAAGCAAAAACAGGTCAAAAATTTGTTAATTATTGGATGCACAATGGTTTTGTCAATGTTGATGGTGAAAA
AATGTCCAAATCATTAGGAAATTTCACAACTGTCCATGAATTACTTCAAGTTGTTGACCCACAAATTTTACGTTTCTTTT
TGACAACAACTCATTACAGAAGACCGCTTAATTTTACTGATGATGCACTGACAGAAGCAGAAAATAATATTAAAAAAATA
GAAAATGCTTATCGACATTTGGATGACCAAGCTGAGTCCAATCTATCGGCTTTGACAACTTTTAGAAATGATTTTGTGGC
TGCTATGGATGAAGATTTCAACATTGCTAATGGAATGACTGTTTTTTATGACTTTGTTTCGTGGGTCAATAAAGGAAATG
GGGGAGCTGAGGTCAAAGCATTCTTTGATCAGGTTTTAGAAATATTAGGCATAAAATTTGAAATTGAACAAAGTTTAGAT
AGTGAAATCGAAGCGATGATTGAAGAGAGACAATTGGCACGAGAAGTCCGTGATTTTGCGAAATCAGATGAAATTCGTGA
TGCTTTGAAGGCTCAAGGAATTGTTCTTGAAGATACAAAAGATGGGGTACGGTGGCATCGTGAATAA

Upstream 100 bases:

>100_bases
TCTTGGTTATTCTGCTTATACAGGAATACCATTGCTCTATCTACCAATACGTTCTCTTGTAACCTCAATTGTTTATGATG
AAGATTAAGAAGGAAATAGA

Downstream 100 bases:

>100_bases
GCAACAAGCAGAACTTTTAAATGGAATTGCCCTTGCCTATGTGGGGGATGCAATATTTGAAGTTTTTGTCCGCGATTACT
TGTTAGAAAAGGGGCTGACA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKIYNTYSRQLEDFQPIEPGKVKMYVCGPTVYNYIHVGNARSVVAFDLVRKYLEFRGFEVEYISNFTDVDDKIIKAAASE
NISTKELSERYIAAFYEDTDLLNVKRASQNPKATEFIEAMIDFIQELLDKDYAYISEGDVYFRVAKSKDYAKLANKNLAD
LLAGASGRTDEETNLKESPADFALWKSVKADEVSWQAPWGAGRPGWHIECSVMSTSLLGETIDIHGGGADLEFPHHTNEI
AQSEAKTGQKFVNYWMHNGFVNVDGEKMSKSLGNFTTVHELLQVVDPQILRFFLTTTHYRRPLNFTDDALTEAENNIKKI
ENAYRHLDDQAESNLSALTTFRNDFVAAMDEDFNIANGMTVFYDFVSWVNKGNGGAEVKAFFDQVLEILGIKFEIEQSLD
SEIEAMIEERQLAREVRDFAKSDEIRDALKAQGIVLEDTKDGVRWHRE

Sequences:

>Translated_448_residues
MKIYNTYSRQLEDFQPIEPGKVKMYVCGPTVYNYIHVGNARSVVAFDLVRKYLEFRGFEVEYISNFTDVDDKIIKAAASE
NISTKELSERYIAAFYEDTDLLNVKRASQNPKATEFIEAMIDFIQELLDKDYAYISEGDVYFRVAKSKDYAKLANKNLAD
LLAGASGRTDEETNLKESPADFALWKSVKADEVSWQAPWGAGRPGWHIECSVMSTSLLGETIDIHGGGADLEFPHHTNEI
AQSEAKTGQKFVNYWMHNGFVNVDGEKMSKSLGNFTTVHELLQVVDPQILRFFLTTTHYRRPLNFTDDALTEAENNIKKI
ENAYRHLDDQAESNLSALTTFRNDFVAAMDEDFNIANGMTVFYDFVSWVNKGNGGAEVKAFFDQVLEILGIKFEIEQSLD
SEIEAMIEERQLAREVRDFAKSDEIRDALKAQGIVLEDTKDGVRWHRE
>Mature_448_residues
MKIYNTYSRQLEDFQPIEPGKVKMYVCGPTVYNYIHVGNARSVVAFDLVRKYLEFRGFEVEYISNFTDVDDKIIKAAASE
NISTKELSERYIAAFYEDTDLLNVKRASQNPKATEFIEAMIDFIQELLDKDYAYISEGDVYFRVAKSKDYAKLANKNLAD
LLAGASGRTDEETNLKESPADFALWKSVKADEVSWQAPWGAGRPGWHIECSVMSTSLLGETIDIHGGGADLEFPHHTNEI
AQSEAKTGQKFVNYWMHNGFVNVDGEKMSKSLGNFTTVHELLQVVDPQILRFFLTTTHYRRPLNFTDDALTEAENNIKKI
ENAYRHLDDQAESNLSALTTFRNDFVAAMDEDFNIANGMTVFYDFVSWVNKGNGGAEVKAFFDQVLEILGIKFEIEQSLD
SEIEAMIEERQLAREVRDFAKSDEIRDALKAQGIVLEDTKDGVRWHRE

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=504, Percent_Identity=30.7539682539683, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI21269877, Length=259, Percent_Identity=37.4517374517375, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI10835051, Length=259, Percent_Identity=37.4517374517375, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI62240992, Length=259, Percent_Identity=37.4517374517375, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI303304987, Length=259, Percent_Identity=37.4517374517375, Blast_Score=187, Evalue=2e-47,
Organism=Escherichia coli, GI1786737, Length=465, Percent_Identity=42.5806451612903, Blast_Score=364, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17509797, Length=257, Percent_Identity=37.3540856031128, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17509795, Length=257, Percent_Identity=37.3540856031128, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324082, Length=262, Percent_Identity=41.2213740458015, Blast_Score=202, Evalue=7e-53,
Organism=Drosophila melanogaster, GI19922218, Length=506, Percent_Identity=33.399209486166, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI19922364, Length=259, Percent_Identity=35.9073359073359, Blast_Score=170, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 50996; Mature: 50996

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYNTYSRQLEDFQPIEPGKVKMYVCGPTVYNYIHVGNARSVVAFDLVRKYLEFRGFEV
CCCCCHHHHHHHHCCCCCCCCEEEEEECCHHHHEEEECCCCHHHHHHHHHHHHHHCCCEE
EYISNFTDVDDKIIKAAASENISTKELSERYIAAFYEDTDLLNVKRASQNPKATEFIEAM
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHH
IDFIQELLDKDYAYISEGDVYFRVAKSKDYAKLANKNLADLLAGASGRTDEETNLKESPA
HHHHHHHHHCCCEEEECCCEEEEEECCCCHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCC
DFALWKSVKADEVSWQAPWGAGRPGWHIECSVMSTSLLGETIDIHGGGADLEFPHHTNEI
HHHHHHCCCCCCCCEECCCCCCCCCCEEEEEEHHHHHCCCEEEECCCCCCCCCCCCHHHH
AQSEAKTGQKFVNYWMHNGFVNVDGEKMSKSLGNFTTVHELLQVVDPQILRFFLTTTHYR
HHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHC
RPLNFTDDALTEAENNIKKIENAYRHLDDQAESNLSALTTFRNDFVAAMDEDFNIANGMT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHH
VFYDFVSWVNKGNGGAEVKAFFDQVLEILGIKFEIEQSLDSEIEAMIEERQLAREVRDFA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
KSDEIRDALKAQGIVLEDTKDGVRWHRE
HHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKIYNTYSRQLEDFQPIEPGKVKMYVCGPTVYNYIHVGNARSVVAFDLVRKYLEFRGFEV
CCCCCHHHHHHHHCCCCCCCCEEEEEECCHHHHEEEECCCCHHHHHHHHHHHHHHCCCEE
EYISNFTDVDDKIIKAAASENISTKELSERYIAAFYEDTDLLNVKRASQNPKATEFIEAM
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHH
IDFIQELLDKDYAYISEGDVYFRVAKSKDYAKLANKNLADLLAGASGRTDEETNLKESPA
HHHHHHHHHCCCEEEECCCEEEEEECCCCHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCC
DFALWKSVKADEVSWQAPWGAGRPGWHIECSVMSTSLLGETIDIHGGGADLEFPHHTNEI
HHHHHHCCCCCCCCEECCCCCCCCCCEEEEEEHHHHHCCCEEEECCCCCCCCCCCCHHHH
AQSEAKTGQKFVNYWMHNGFVNVDGEKMSKSLGNFTTVHELLQVVDPQILRFFLTTTHYR
HHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHC
RPLNFTDDALTEAENNIKKIENAYRHLDDQAESNLSALTTFRNDFVAAMDEDFNIANGMT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHH
VFYDFVSWVNKGNGGAEVKAFFDQVLEILGIKFEIEQSLDSEIEAMIEERQLAREVRDFA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
KSDEIRDALKAQGIVLEDTKDGVRWHRE
HHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]