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The map label for this gene is aspB [H]

Identifier: 125624794

GI number: 125624794

Start: 2004314

End: 2005495

Strand: Reverse

Name: aspB [H]

Synonym: llmg_2019

Alternate gene names: 125624794

Gene position: 2005495-2004314 (Counterclockwise)

Preceding gene: 125624795

Following gene: 125624793

Centisome position: 79.28

GC content: 37.65

Gene sequence:

>1182_bases
ATGAAAAAATGTTCTGATTTTGTATTAAAAATGGATGAGTCTGTGACCCTTGCGGCGGCCAATCGTGCCAAAGCATTAAA
AGCACAAGGACGAGATATTATCGACTTGACCCTTGGTCAACCAGACTTTCCAACTCCTAAAAAAATTGGTCAAGCGGCCA
TCGAAGCGATAAATAATGGACAAGCTAGTTTTTATACACAAGCTGGTGGACTTCCAGAACTTAAAAAAGCCGTTCAACAT
TATTGGACACGTTTTTATGCTTATGAAATTCAAACAAACGAAATATTAATTACGGCTGGGGCAAAGTTTGCCCTCTACGC
TTACTTTATGGCAACTGTTGATCCTTTAGATGAGGTAATCATACCAGCACCTTATTGGGTTTCTTATGTCGACCAAGTAA
AAATGGCTGGTGGAAATCCAGTAATTGTAGAAGCTAAGCAAGAAAATAACTTTAAAGTTACGGTTGAGCAATTAGAAAAA
GCAAGAACAAGCAAAACTAAGATTTTATTACTAAATTCGCCTTCAAATCCAACAGGAATGATTTATTCTAAAGAAGAATT
AACAGCCATTGGAGAATGGGCAGTTGCTCATGATTTATTGATTTTGGCCGATGATATCTATCATCGTTTGGTTTATAATG
GAGCAGAATTTACAGCAATTTCAAGCCTGTCTGATGAAATCAGAAACAGAACAACAGTGATTAATGGTGTTTCTAAAACA
TTTGCAATGACTGGTTGGCGAATTGGTTTAGCCGTAGGTGATCCAGAAATTATTGCTGCAATGACTAAAATTGCCAGTCA
AACCACTTCAAATCCGACCGCTGTTGCTCAATATGCTGCCATAGAGGCATTTGAAGAAAATGATAAAAGTTTTGAGAAAA
TGCATGCTGCATTTGAAGAACGCTTAAATAAAATTTATCTTCAACTTTCAGAAGTTCCTGGTTTTGAACTTGTGAAACCA
AATGGTGCTTTCTATTTGTTCCCGAAAGTGACCAAGGCTATGGCGATGAAAGGCTATACAGATGTGACTGATTTTACGAC
AGCCATTCTTGAAGAAGCTGGGGTAGCTTTAGTTACAGGAGCAGGTTTTGGTTCTCCAGAAAATGTTCGTTTGAGTTATG
CAACAAGTCTTGAAACTCTGGAAGCTGCAGTAACAAGATTAAAGGATTGGATGAATGATTGA

Upstream 100 bases:

>100_bases
AATCAGTTGTTTTAGCGCTTTACAAAGGGAAACCAGCCTGGGAAGTAAATAATAGCAATGGATTTAAAGTTTATGACTTT
GAGTCAGGAAAAGAGTTGAT

Downstream 100 bases:

>100_bases
TAAAAAAGAAGCAAAATCAGCTTATAAACTCTCTAAAAAAATAGGGGCAGTTGTTGCTTATAAAAATTTAGAAACAAATG
AACGCTATATTGATATAGCA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKKCSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKKIGQAAIEAINNGQASFYTQAGGLPELKKAVQH
YWTRFYAYEIQTNEILITAGAKFALYAYFMATVDPLDEVIIPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEK
ARTSKTKILLLNSPSNPTGMIYSKEELTAIGEWAVAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRNRTTVINGVSKT
FAMTGWRIGLAVGDPEIIAAMTKIASQTTSNPTAVAQYAAIEAFEENDKSFEKMHAAFEERLNKIYLQLSEVPGFELVKP
NGAFYLFPKVTKAMAMKGYTDVTDFTTAILEEAGVALVTGAGFGSPENVRLSYATSLETLEAAVTRLKDWMND

Sequences:

>Translated_393_residues
MKKCSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKKIGQAAIEAINNGQASFYTQAGGLPELKKAVQH
YWTRFYAYEIQTNEILITAGAKFALYAYFMATVDPLDEVIIPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEK
ARTSKTKILLLNSPSNPTGMIYSKEELTAIGEWAVAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRNRTTVINGVSKT
FAMTGWRIGLAVGDPEIIAAMTKIASQTTSNPTAVAQYAAIEAFEENDKSFEKMHAAFEERLNKIYLQLSEVPGFELVKP
NGAFYLFPKVTKAMAMKGYTDVTDFTTAILEEAGVALVTGAGFGSPENVRLSYATSLETLEAAVTRLKDWMND
>Mature_393_residues
MKKCSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKKIGQAAIEAINNGQASFYTQAGGLPELKKAVQH
YWTRFYAYEIQTNEILITAGAKFALYAYFMATVDPLDEVIIPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEK
ARTSKTKILLLNSPSNPTGMIYSKEELTAIGEWAVAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRNRTTVINGVSKT
FAMTGWRIGLAVGDPEIIAAMTKIASQTTSNPTAVAQYAAIEAFEENDKSFEKMHAAFEERLNKIYLQLSEVPGFELVKP
NGAFYLFPKVTKAMAMKGYTDVTDFTTAILEEAGVALVTGAGFGSPENVRLSYATSLETLEAAVTRLKDWMND

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=27.3417721518987, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=27.3417721518987, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI56713254, Length=394, Percent_Identity=26.1421319796954, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI56713256, Length=394, Percent_Identity=26.1421319796954, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=25.8278145695364, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4507369, Length=392, Percent_Identity=23.7244897959184, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI149944424, Length=219, Percent_Identity=27.3972602739726, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1788722, Length=367, Percent_Identity=26.4305177111717, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788627, Length=390, Percent_Identity=26.9230769230769, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=25.2717391304348, Blast_Score=131, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=397, Percent_Identity=28.2115869017632, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71994472, Length=410, Percent_Identity=28.2926829268293, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71994476, Length=410, Percent_Identity=28.2926829268293, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=24.5989304812834, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71981209, Length=370, Percent_Identity=22.7027027027027, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=27.2493573264781, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320317, Length=369, Percent_Identity=24.1192411924119, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323118, Length=342, Percent_Identity=23.3918128654971, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573069, Length=391, Percent_Identity=27.6214833759591, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24646114, Length=391, Percent_Identity=27.6214833759591, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI28573067, Length=391, Percent_Identity=27.6214833759591, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI28573065, Length=391, Percent_Identity=27.6214833759591, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=24.9336870026525, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641770, Length=377, Percent_Identity=23.6074270557029, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641760, Length=377, Percent_Identity=23.6074270557029, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641768, Length=377, Percent_Identity=23.6074270557029, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641766, Length=377, Percent_Identity=23.6074270557029, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641764, Length=377, Percent_Identity=23.6074270557029, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45551451, Length=377, Percent_Identity=23.6074270557029, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43221; Mature: 43221

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKCSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKKIGQAAIEAINNG
CCCHHHHHEECCCCEEEEECCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
QASFYTQAGGLPELKKAVQHYWTRFYAYEIQTNEILITAGAKFALYAYFMATVDPLDEVI
CCEEEECCCCCHHHHHHHHHHHHHEEEEEEECCEEEEECCCHHHHHHHHHHHHCCHHHHE
IPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEKARTSKTKILLLNSPSNPTGM
ECCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEHHHHHHHCCCCEEEEEEECCCCCCCE
IYSKEELTAIGEWAVAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRNRTTVINGVSKT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCHHH
FAMTGWRIGLAVGDPEIIAAMTKIASQTTSNPTAVAQYAAIEAFEENDKSFEKMHAAFEE
HEECCEEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RLNKIYLQLSEVPGFELVKPNGAFYLFPKVTKAMAMKGYTDVTDFTTAILEEAGVALVTG
HHHHHEEEHCCCCCEEEECCCCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEE
AGFGSPENVRLSYATSLETLEAAVTRLKDWMND
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKCSDFVLKMDESVTLAAANRAKALKAQGRDIIDLTLGQPDFPTPKKIGQAAIEAINNG
CCCHHHHHEECCCCEEEEECCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCC
QASFYTQAGGLPELKKAVQHYWTRFYAYEIQTNEILITAGAKFALYAYFMATVDPLDEVI
CCEEEECCCCCHHHHHHHHHHHHHEEEEEEECCEEEEECCCHHHHHHHHHHHHCCHHHHE
IPAPYWVSYVDQVKMAGGNPVIVEAKQENNFKVTVEQLEKARTSKTKILLLNSPSNPTGM
ECCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEHHHHHHHCCCCEEEEEEECCCCCCCE
IYSKEELTAIGEWAVAHDLLILADDIYHRLVYNGAEFTAISSLSDEIRNRTTVINGVSKT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCHHH
FAMTGWRIGLAVGDPEIIAAMTKIASQTTSNPTAVAQYAAIEAFEENDKSFEKMHAAFEE
HEECCEEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RLNKIYLQLSEVPGFELVKPNGAFYLFPKVTKAMAMKGYTDVTDFTTAILEEAGVALVTG
HHHHHEEEHCCCCCEEEECCCCCEEECHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEE
AGFGSPENVRLSYATSLETLEAAVTRLKDWMND
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]