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The map label for this gene is atpB [H]

Identifier: 125624730

GI number: 125624730

Start: 1932725

End: 1933438

Strand: Reverse

Name: atpB [H]

Synonym: llmg_1951

Alternate gene names: 125624730

Gene position: 1933438-1932725 (Counterclockwise)

Preceding gene: 125624731

Following gene: 125624729

Centisome position: 76.44

GC content: 40.62

Gene sequence:

>714_bases
ATGGAATCAACATGGACCTTTAATATTGGGCCAATTCCATTTGATGGAACAATCACAGTAATGACTTTTGTGACTGTCCT
CATTGTTTTCGGTCTGGTATTCTGGGCGAGCCGCAATATGCAGCTCAAGCCCAAAGGTAAACAAAATGTTCTTGAGTGGG
TTGTTGATTTTGTCAATGGAGTTTCCAAAGATAACGTCGGCCCTCATGAAGCACCACGCTTTGGCCTCATGAACTTTACC
CTCTTTTCTTTCCTTCTTATTGCCAACTGCATTGGGCTAGTAACTAAAATTAGTACGCCAGGTGATGTTTCTCTTTGGAA
ATCACCAACTGCAAATCCAACAGTCGATTTGACACTTGCACTTCTTGTTGTTGTAATGTCAAATACACTGGGTGTACAAA
AATTCGGTTTTAAAGGTTACCTCAAGGTTGCCTTCTGGAAAGATCCGAAAGGTCTTCTTCCAATGAACATTTTGGAAGAA
TTTACAAATGCACTTTCACTTGGTTTACGGCTTTATGGGAATATCTTCGCGGGTGAAATCATGCTTGGTCTTATTGCCGG
TATGATTCAATCAACCATGTGGATGCTTCCAGTTGCGTGGATTCTAGAAGTTGCATGGATTGGCTTTTCACTTTTCATTT
CAGCCCTCCAAGCTTATGTCTTTGTCCTTTTGACAAACTTGTACATTAGCCACAAAATCATAGCAGAACATTAA

Upstream 100 bases:

>100_bases
TTCGTCGAAGGTACATTCTTCATCGCCCTTGCTATGGCATTCCTTTTCCGTTAAAATTTTTCTCAACAAAAAATTTTAAA
AACAGAAAGGAAGAACAGGT

Downstream 100 bases:

>100_bases
GAAAGGAGTAGAAATTGTCAACATTATTATTAGAAGCTGCTCCGAATACCGTTCTCGGTAACATCATCGTTGTATCTGGT
GCATTTATTATCTTATTGGT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MESTWTFNIGPIPFDGTITVMTFVTVLIVFGLVFWASRNMQLKPKGKQNVLEWVVDFVNGVSKDNVGPHEAPRFGLMNFT
LFSFLLIANCIGLVTKISTPGDVSLWKSPTANPTVDLTLALLVVVMSNTLGVQKFGFKGYLKVAFWKDPKGLLPMNILEE
FTNALSLGLRLYGNIFAGEIMLGLIAGMIQSTMWMLPVAWILEVAWIGFSLFISALQAYVFVLLTNLYISHKIIAEH

Sequences:

>Translated_237_residues
MESTWTFNIGPIPFDGTITVMTFVTVLIVFGLVFWASRNMQLKPKGKQNVLEWVVDFVNGVSKDNVGPHEAPRFGLMNFT
LFSFLLIANCIGLVTKISTPGDVSLWKSPTANPTVDLTLALLVVVMSNTLGVQKFGFKGYLKVAFWKDPKGLLPMNILEE
FTNALSLGLRLYGNIFAGEIMLGLIAGMIQSTMWMLPVAWILEVAWIGFSLFISALQAYVFVLLTNLYISHKIIAEH
>Mature_237_residues
MESTWTFNIGPIPFDGTITVMTFVTVLIVFGLVFWASRNMQLKPKGKQNVLEWVVDFVNGVSKDNVGPHEAPRFGLMNFT
LFSFLLIANCIGLVTKISTPGDVSLWKSPTANPTVDLTLALLVVVMSNTLGVQKFGFKGYLKVAFWKDPKGLLPMNILEE
FTNALSLGLRLYGNIFAGEIMLGLIAGMIQSTMWMLPVAWILEVAWIGFSLFISALQAYVFVLLTNLYISHKIIAEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=202, Percent_Identity=30.6930693069307, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 26326; Mature: 26326

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESTWTFNIGPIPFDGTITVMTFVTVLIVFGLVFWASRNMQLKPKGKQNVLEWVVDFVNG
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
VSKDNVGPHEAPRFGLMNFTLFSFLLIANCIGLVTKISTPGDVSLWKSPTANPTVDLTLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHH
LLVVVMSNTLGVQKFGFKGYLKVAFWKDPKGLLPMNILEEFTNALSLGLRLYGNIFAGEI
HHHHHHHCCCCCHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGLIAGMIQSTMWMLPVAWILEVAWIGFSLFISALQAYVFVLLTNLYISHKIIAEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESTWTFNIGPIPFDGTITVMTFVTVLIVFGLVFWASRNMQLKPKGKQNVLEWVVDFVNG
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
VSKDNVGPHEAPRFGLMNFTLFSFLLIANCIGLVTKISTPGDVSLWKSPTANPTVDLTLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHH
LLVVVMSNTLGVQKFGFKGYLKVAFWKDPKGLLPMNILEEFTNALSLGLRLYGNIFAGEI
HHHHHHHCCCCCHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGLIAGMIQSTMWMLPVAWILEVAWIGFSLFISALQAYVFVLLTNLYISHKIIAEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]