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The map label for this gene is atpD [H]

Identifier: 125624725

GI number: 125624725

Start: 1927518

End: 1928978

Strand: Reverse

Name: atpD [H]

Synonym: llmg_1946

Alternate gene names: 125624725

Gene position: 1928978-1927518 (Counterclockwise)

Preceding gene: 125624726

Following gene: 125624724

Centisome position: 76.26

GC content: 41.96

Gene sequence:

>1461_bases
ATGAATAGAAATTCTGTTGTTAGACAGAAAATAAAAACAGGAGGAAAAACATTGAGTTCTGGTAAAATTACTCAGGTTAT
CGGTCCCGTCGTTGACGTGGAATTTGGTTCTGATGCCAAACTGCCTGAGATTAACAATGCCTTGATTGTCTACAAAGATG
TCAATGGTTTAAAAACAAAAATTACTCTTGAAGTTGCTTTGGAACTTGGTGATGGTGCAGTTCGTACGATCGCTATGGAA
TCTACTGATGGATTGACTCGTGGACTTGAAGTCCTTGATACAGGTAAAGCGGTCAGCGTTCCTGTTGGTGAATCTACTCT
TGGTCGTGTTTTTAATGTCCTTGGTGACGTTATTGATGGTGGAGAAGATTTCCCTGCTGATGCAGAACGTAATCCTATCC
ACAAGAAAGCTCCAACTTTTGACGAATTGTCAACTGCAAATGAAGTTCTTGTAACAGGGATTAAAGTTGTCGATTTACTT
GCCCCTTATCTTAAAGGTGGGAAAGTCGGACTCTTCGGTGGTGCCGGTGTTGGTAAAACCGTCCTTATCCAAGAATTGAT
TCACAATATTGCCCAAGAACACGGTGGTATTTCTGTATTTACAGGTGTTGGGGAACGTACTCGTGAAGGGAATGACCTTT
ACTGGGAAATGAAAGAATCAGGCGTTATTGAAAAAACAGCCATGGTCTTTGGTCAAATGAATGAACCACCTGGAGCACGT
ATGCGTGTTGCCCTTACTGGTTTAACAATTGCGGAATATTTCCGTGATGTTCAAGGACAAGACGTATTGCTTTTCATCGA
TAACATCTTCCGTTTCACTCAAGCTGGTTCAGAAGTTTCTGCCCTTTTGGGACGTATGCCTTCTGCCGTTGGTTACCAAC
CAACTCTTGCAACTGAAATGGGTCAATTACAAGAACGTATCACTTCTACTAAGAAGGGTTCTGTTACATCTATCCAAGCG
ATTTATGTCCCTGCCGATGACTATACTGACCCAGCGCCAGCTACAGCCTTCGCTCACTTGGACGCAACAACTAACTTGGA
ACGTCGTTTGACACAAATGGGTATCTATCCAGCCGTTGACCCACTTGCTTCATCATCACGTGCGCTTACACCTGAAATTG
TTGGTGAAGAACACTATGAAGTTGCAATGGAAGTTCAACGTGTCCTTCAACGCTACAAAGAATTGCAAGATATCATTGCC
ATTCTTGGTATGGATGAATTGTCAGATGATGAAAAAATTCTCGTTGGACGTGCACGTCGTATCCAATTCTTCCTTTCACA
AAACTTCCACGTTGCTGAACAGTTTACTGGTCAACCTGGTTCATATGTACCAATTGACAAAACAGTTCATGACTTCAAGG
AAATTTTGGAAGGTAAATATGACGAAGTCCCTGAAGATGCTTTCCGTGGAGTAGGTCCAATTGAAGACGTACTTGCAAAA
GCAAAATCAATGGGTTATTAA

Upstream 100 bases:

>100_bases
CAATGTTACGATTTATCAACTTGAGGAATAAATGTTCTGTCAGTAAAGGCTTTGAATTTTAAATACGTTTGTCAGTAAAT
TTTTACTGATTAGCTTAAAA

Downstream 100 bases:

>100_bases
TTCGATTTCTTATGAAATGACAAAGTGAAAATACATTATTGAATCGCAAAATTTACTGACAATAATTCTGTCAGTAAAAG
TTGCTTCAACTTTTTTAAAG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNRNSVVRQKIKTGGKTLSSGKITQVIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTIAME
STDGLTRGLEVLDTGKAVSVPVGESTLGRVFNVLGDVIDGGEDFPADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLL
APYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGAR
MRVALTGLTIAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQA
IYVPADDYTDPAPATAFAHLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIA
ILGMDELSDDEKILVGRARRIQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLAK
AKSMGY

Sequences:

>Translated_486_residues
MNRNSVVRQKIKTGGKTLSSGKITQVIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTIAME
STDGLTRGLEVLDTGKAVSVPVGESTLGRVFNVLGDVIDGGEDFPADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLL
APYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGAR
MRVALTGLTIAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQA
IYVPADDYTDPAPATAFAHLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIA
ILGMDELSDDEKILVGRARRIQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLAK
AKSMGY
>Mature_486_residues
MNRNSVVRQKIKTGGKTLSSGKITQVIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTKITLEVALELGDGAVRTIAME
STDGLTRGLEVLDTGKAVSVPVGESTLGRVFNVLGDVIDGGEDFPADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLL
APYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGAR
MRVALTGLTIAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQA
IYVPADDYTDPAPATAFAHLDATTNLERRLTQMGIYPAVDPLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIA
ILGMDELSDDEKILVGRARRIQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLAK
AKSMGY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=474, Percent_Identity=66.2447257383966, Blast_Score=617, Evalue=1e-177,
Organism=Homo sapiens, GI19913424, Length=349, Percent_Identity=27.2206303724928, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI19913428, Length=342, Percent_Identity=25.7309941520468, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI19913426, Length=361, Percent_Identity=25.207756232687, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI50345984, Length=345, Percent_Identity=26.9565217391304, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4757810, Length=345, Percent_Identity=26.9565217391304, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI1790170, Length=467, Percent_Identity=63.169164882227, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1788251, Length=316, Percent_Identity=31.0126582278481, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1790172, Length=319, Percent_Identity=28.5266457680251, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=473, Percent_Identity=63.6363636363636, Blast_Score=588, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17565854, Length=358, Percent_Identity=29.3296089385475, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17570191, Length=400, Percent_Identity=24.75, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=431, Percent_Identity=24.3619489559165, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988080, Length=349, Percent_Identity=26.9340974212034, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=349, Percent_Identity=26.9340974212034, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=412, Percent_Identity=25, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6322581, Length=465, Percent_Identity=68.3870967741936, Blast_Score=613, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319603, Length=421, Percent_Identity=25.6532066508314, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319370, Length=379, Percent_Identity=28.2321899736148, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320016, Length=280, Percent_Identity=26.0714285714286, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24638766, Length=473, Percent_Identity=65.7505285412262, Blast_Score=607, Evalue=1e-174,
Organism=Drosophila melanogaster, GI28574560, Length=486, Percent_Identity=63.3744855967078, Blast_Score=589, Evalue=1e-168,
Organism=Drosophila melanogaster, GI20129479, Length=347, Percent_Identity=27.0893371757925, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24583988, Length=353, Percent_Identity=28.0453257790368, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583986, Length=353, Percent_Identity=28.0453257790368, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583984, Length=353, Percent_Identity=28.0453257790368, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583992, Length=349, Percent_Identity=26.9340974212034, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281361666, Length=410, Percent_Identity=25.3658536585366, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24646341, Length=410, Percent_Identity=25.3658536585366, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136796, Length=410, Percent_Identity=25.3658536585366, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24658560, Length=363, Percent_Identity=26.9972451790634, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24638768, Length=96, Percent_Identity=53.125, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 52749; Mature: 52749

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRNSVVRQKIKTGGKTLSSGKITQVIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTK
CCCHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEE
ITLEVALELGDGAVRTIAMESTDGLTRGLEVLDTGKAVSVPVGESTLGRVFNVLGDVIDG
EEEEEEEECCCCCEEEEEECCCCCHHHCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCC
GEDFPADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLLAPYLKGGKVGLFGGAGVGKT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHH
VLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGAR
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCE
MRVALTGLTIAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEM
EEEEEEHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHH
GQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDATTNLERRLTQMGIYPAVD
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCC
PLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIAILGMDELSDDEKILVGRARR
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHH
IQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLAK
EEEECCCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHH
AKSMGY
HHHCCC
>Mature Secondary Structure
MNRNSVVRQKIKTGGKTLSSGKITQVIGPVVDVEFGSDAKLPEINNALIVYKDVNGLKTK
CCCHHHHHHHHHHCCCCCCCCCHHHHHCCEEEEECCCCCCCCCCCCCEEEEECCCCCEEE
ITLEVALELGDGAVRTIAMESTDGLTRGLEVLDTGKAVSVPVGESTLGRVFNVLGDVIDG
EEEEEEEECCCCCEEEEEECCCCCHHHCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCC
GEDFPADAERNPIHKKAPTFDELSTANEVLVTGIKVVDLLAPYLKGGKVGLFGGAGVGKT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHH
VLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGAR
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCE
MRVALTGLTIAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEM
EEEEEEHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHH
GQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDATTNLERRLTQMGIYPAVD
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCC
PLASSSRALTPEIVGEEHYEVAMEVQRVLQRYKELQDIIAILGMDELSDDEKILVGRARR
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHH
IQFFLSQNFHVAEQFTGQPGSYVPIDKTVHDFKEILEGKYDEVPEDAFRGVGPIEDVLAK
EEEECCCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHH
AKSMGY
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]