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The map label for this gene is lutA [H]

Identifier: 125624697

GI number: 125624697

Start: 1895665

End: 1896435

Strand: Direct

Name: lutA [H]

Synonym: llmg_1915

Alternate gene names: 125624697

Gene position: 1895665-1896435 (Clockwise)

Preceding gene: 125624696

Following gene: 125624698

Centisome position: 74.94

GC content: 36.84

Gene sequence:

>771_bases
ATGAAAGTTTCAATATTCTCCACTTGTGTGATGGACCTAATGTTTCCACAAGTTGGAATTGCAATGGTTGAAGTCCTTGA
ACGTTTAGGGATTGAAACAGATTTACCAGAAGGACAAATTTGCTGTGGACAGCCCACTTATAATTCTGGCTTAGTCAAAG
AATCTATGCCAACAATCAAAAATCAGATTGATGCCTTTGAATCTTCTGATTATGTTGTTGGTATTGCTGGTTCTTGCTCA
GGGATGTTTACAGAATACCCTCATATGTTTGATGAAGGTGACCCTTATAAGCAAAAAGCCATTGATTTGGCCAATAAATC
TTATGAATTTACCCAATTTCTTTACCGTGTCTTAGGTCTTGAGGACCTTGGCGCAACTTTTAAGGGTGAAAAGGCCACTT
ATCATCGTTCTTGCCACATGACAAGAATCTTAGGCGAACGAGAAGCGCCATTTATCTTATTAGATAAAGTGAAAGGTCTT
GAAGTTCTACCTCTTCCTCATTTAGAAAATTGTTGTGGTTTTGGTGGAACTTTCTCAGTTAAATCTCCTGAAATTTCGGA
AATGATGGTCACTGAAAAAACAAATGATATCTTATCAACAGGTGCTGAAATTTTAATCTCTGCCGACCTTGGTTGTTTGA
TGAATATTGCTGGAAAACTAAATCGTGAAGGCAAAAAAATAAGAGTGATGCATATCGCCGAAATTTTAAACACAAATGTT
GATTTGGAACGAATCGATACTGTGAAAAATCCAGAATTCATAAGAGCATAG

Upstream 100 bases:

>100_bases
TTTTTTGAAAATCTAAATGAATCGGCTTATAATGAAAGAGCATACATCTCTAGAAGATGTCCAATATTTAACAAAGATTT
CAAAATACTAAGGAGCACTT

Downstream 100 bases:

>100_bases
GGGGAGAAAATGGGACTTTCAACAAGTACAAAAACTTTCGCTGAACGTTTAGAAGAAAGTAAAAAAGACCAATTTGCCAA
GGCTGCGGTGGCTAAAGCAC

Product: putative Fe-S oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKVSIFSTCVMDLMFPQVGIAMVEVLERLGIETDLPEGQICCGQPTYNSGLVKESMPTIKNQIDAFESSDYVVGIAGSCS
GMFTEYPHMFDEGDPYKQKAIDLANKSYEFTQFLYRVLGLEDLGATFKGEKATYHRSCHMTRILGEREAPFILLDKVKGL
EVLPLPHLENCCGFGGTFSVKSPEISEMMVTEKTNDILSTGAEILISADLGCLMNIAGKLNREGKKIRVMHIAEILNTNV
DLERIDTVKNPEFIRA

Sequences:

>Translated_256_residues
MKVSIFSTCVMDLMFPQVGIAMVEVLERLGIETDLPEGQICCGQPTYNSGLVKESMPTIKNQIDAFESSDYVVGIAGSCS
GMFTEYPHMFDEGDPYKQKAIDLANKSYEFTQFLYRVLGLEDLGATFKGEKATYHRSCHMTRILGEREAPFILLDKVKGL
EVLPLPHLENCCGFGGTFSVKSPEISEMMVTEKTNDILSTGAEILISADLGCLMNIAGKLNREGKKIRVMHIAEILNTNV
DLERIDTVKNPEFIRA
>Mature_256_residues
MKVSIFSTCVMDLMFPQVGIAMVEVLERLGIETDLPEGQICCGQPTYNSGLVKESMPTIKNQIDAFESSDYVVGIAGSCS
GMFTEYPHMFDEGDPYKQKAIDLANKSYEFTQFLYRVLGLEDLGATFKGEKATYHRSCHMTRILGEREAPFILLDKVKGL
EVLPLPHLENCCGFGGTFSVKSPEISEMMVTEKTNDILSTGAEILISADLGCLMNIAGKLNREGKKIRVMHIAEILNTNV
DLERIDTVKNPEFIRA

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=237, Percent_Identity=43.4599156118143, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI48994913, Length=251, Percent_Identity=24.3027888446215, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788576, Length=230, Percent_Identity=26.5217391304348, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 28422; Mature: 28422

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSIFSTCVMDLMFPQVGIAMVEVLERLGIETDLPEGQICCGQPTYNSGLVKESMPTIK
CEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHH
NQIDAFESSDYVVGIAGSCSGMFTEYPHMFDEGDPYKQKAIDLANKSYEFTQFLYRVLGL
HHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCH
EDLGATFKGEKATYHRSCHMTRILGEREAPFILLDKVKGLEVLPLPHLENCCGFGGTFSV
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCHHHHHCCCCEECC
KSPEISEMMVTEKTNDILSTGAEILISADLGCLMNIAGKLNREGKKIRVMHIAEILNTNV
CCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCC
DLERIDTVKNPEFIRA
CHHHHHCCCCCHHHCC
>Mature Secondary Structure
MKVSIFSTCVMDLMFPQVGIAMVEVLERLGIETDLPEGQICCGQPTYNSGLVKESMPTIK
CEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHH
NQIDAFESSDYVVGIAGSCSGMFTEYPHMFDEGDPYKQKAIDLANKSYEFTQFLYRVLGL
HHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCH
EDLGATFKGEKATYHRSCHMTRILGEREAPFILLDKVKGLEVLPLPHLENCCGFGGTFSV
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCHHHHHCCCCEECC
KSPEISEMMVTEKTNDILSTGAEILISADLGCLMNIAGKLNREGKKIRVMHIAEILNTNV
CCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCC
DLERIDTVKNPEFIRA
CHHHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]