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The map label for this gene is dtpT [H]

Identifier: 125624653

GI number: 125624653

Start: 1846343

End: 1847836

Strand: Reverse

Name: dtpT [H]

Synonym: llmg_1865

Alternate gene names: 125624653

Gene position: 1847836-1846343 (Counterclockwise)

Preceding gene: 125624654

Following gene: 125624652

Centisome position: 73.05

GC content: 38.35

Gene sequence:

>1494_bases
ATGCAAAACTTAAACAAAACAGAAAAAACATTTTTCGGTCAACCTCGCGGCCTATTGACGCTTTTTCAGACTGAGTTCTG
GGAGCGTTTTTCTTACTATGGGATGCGTGCCATTCTGGTTTATTACCTCTATGCATTGACAACTGCAGATAACGCAGGTT
TAGGACTTCCTAAAGCTCAGGCAATGGCGATTGTAAGTATTTATGGTGCACTTGTCTATCTTTCAACAATTGTTGGGGGA
TGGGTTGCTGACCGGTTGTTGGGCGCTTCGCGCACAATCTTCTTGGGTGGTATTTTAATCACTTTAGGACACGTCGCTTT
AGCAACACCATTTGGTTTATCTTCACTCTTCGTGGCATTATTCTTGATTATCTTAGGAACAGGGATGCTTAAACCCAATA
TTTCTAACATGGTTGGGCATCTATATTCAAAAGATGACTCACGTCGTGATACTGGATTTAATATCTTTGTAGTCGGAATT
AATATGGGTTCTCTGATTGCTCCATTGATTGTTGGGACAGTTGGACAAGGCGTGAACTACCACTTAGGTTTCTCACTTGC
CGCAATCGGAATGATTTTTGCATTATTTGCTTATTGGTATGGACGTCTTCGTCATTTCCCAGAAATTGGACGTGAACCAT
CTAATCCAATGGATGCAAAAGCAAAACGTAATTTTATTATTACATTAACGATTGTTCTTATCGTTGCTTTAATCGGATTT
TTCTTAATTTATCAAGCAAGTCCTGCGAATTTCATCAATAATTTCATTAACGTTTTATCAATTATCGGTATTGTTGTTCC
AATTATTTATTTCGTAATGATGTTTACCTCTAAAAAGGTAGAATCAGACGAACGTCGTAAATTAACGGCTTATATTCCTT
TGTTCCTTTCTGCTATTGTCTTTTGGGCAATTGAAGAACAAAGTTCTACGATTATTGCGGTTTGGGGAGAATCACGTTCT
AACTTAAATCCTACTTGGTTTGGATTTACTTTCCATATTGACCCATCTTGGTACCAATTGTTGAACCCACTCTTCATCGT
TCTCTTGTCACCTATCTTTGTACGAATTTGGAACAAATTAGGAGATCGTCAACCATCAACCATCGTTAAATTTGGTCTTG
GACTGATGTTGACCGGAGCTTCTTATTTGATTATGACACTTCCTGGACTCTTGAATGGGACTTCTGGACGTGCGAGTGCT
CTTTGGCTAGTATTGATGTTTGCTGTTCAAATGGCAGGTGAATTACTTGTTTCACCAGTTGGTTTATCAGTTTCAACAAA
ATTAGCGCCAGTAGCATTCCAATCTCAAATGATGGCAATGTGGTTCTTGGCAGACTCAACTTCACAAGCGATTAATGCCC
AAATTACACCTATCTTTAAAGCAGCAACAGAAGTTCACTTCTTTGCAATTACAGGGATTATCGGTATTATCGTTGGAATC
ATCCTCCTTATTATCAAAAAACCTATTTTGAAATTAATGGGAGATGTTCGTTAA

Upstream 100 bases:

>100_bases
TGTTATTGTCCCTCTTTTTCCCGCGTTTTTCAAAGAATCTGTATAGGCAAAATTGTTTGACAACTTGACAAGTTGTATAG
AAAACTTTATAATATAATCT

Downstream 100 bases:

>100_bases
TTAGTAAAGGAATGAAAAAACCTATCTTGAGAGATAGGTTTTTTTGTATCTTTAAAATGACATTGTTGCTCCTGAGGTTA
CTCTTGTTAAATAATTTTTA

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQAMAIVSIYGALVYLSTIVGG
WVADRLLGASRTIFLGGILITLGHVALATPFGLSSLFVALFLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGI
NMGSLIAPLIVGTVGQGVNYHLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDAKAKRNFIITLTIVLIVALIGF
FLIYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIVFWAIEEQSSTIIAVWGESRS
NLNPTWFGFTFHIDPSWYQLLNPLFIVLLSPIFVRIWNKLGDRQPSTIVKFGLGLMLTGASYLIMTLPGLLNGTSGRASA
LWLVLMFAVQMAGELLVSPVGLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPIFKAATEVHFFAITGIIGIIVGI
ILLIIKKPILKLMGDVR

Sequences:

>Translated_497_residues
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQAMAIVSIYGALVYLSTIVGG
WVADRLLGASRTIFLGGILITLGHVALATPFGLSSLFVALFLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGI
NMGSLIAPLIVGTVGQGVNYHLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDAKAKRNFIITLTIVLIVALIGF
FLIYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIVFWAIEEQSSTIIAVWGESRS
NLNPTWFGFTFHIDPSWYQLLNPLFIVLLSPIFVRIWNKLGDRQPSTIVKFGLGLMLTGASYLIMTLPGLLNGTSGRASA
LWLVLMFAVQMAGELLVSPVGLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPIFKAATEVHFFAITGIIGIIVGI
ILLIIKKPILKLMGDVR
>Mature_497_residues
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQAMAIVSIYGALVYLSTIVGG
WVADRLLGASRTIFLGGILITLGHVALATPFGLSSLFVALFLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGI
NMGSLIAPLIVGTVGQGVNYHLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDAKAKRNFIITLTIVLIVALIGF
FLIYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIVFWAIEEQSSTIIAVWGESRS
NLNPTWFGFTFHIDPSWYQLLNPLFIVLLSPIFVRIWNKLGDRQPSTIVKFGLGLMLTGASYLIMTLPGLLNGTSGRASA
LWLVLMFAVQMAGELLVSPVGLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPIFKAATEVHFFAITGIIGIIVGI
ILLIIKKPILKLMGDVR

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=219, Percent_Identity=32.8767123287671, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI226371746, Length=368, Percent_Identity=28.804347826087, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI226371748, Length=357, Percent_Identity=26.890756302521, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787922, Length=447, Percent_Identity=27.2930648769575, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789911, Length=499, Percent_Identity=30.060120240481, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1790572, Length=477, Percent_Identity=28.3018867924528, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1786927, Length=508, Percent_Identity=30.1181102362205, Blast_Score=176, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17569141, Length=372, Percent_Identity=27.1505376344086, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71987453, Length=186, Percent_Identity=32.7956989247312, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639583, Length=373, Percent_Identity=27.6139410187668, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24639585, Length=373, Percent_Identity=27.6139410187668, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24639581, Length=373, Percent_Identity=27.6139410187668, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28571098, Length=411, Percent_Identity=24.5742092457421, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571102, Length=411, Percent_Identity=24.5742092457421, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571100, Length=411, Percent_Identity=24.5742092457421, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54792; Mature: 54792

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQ
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
AMAIVSIYGALVYLSTIVGGWVADRLLGASRTIFLGGILITLGHVALATPFGLSSLFVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGINMGSLIAPLIVGTVGQGVNY
HHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCE
HLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDAKAKRNFIITLTIVLIVALIGF
EHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHH
FLIYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FWAIEEQSSTIIAVWGESRSNLNPTWFGFTFHIDPSWYQLLNPLFIVLLSPIFVRIWNKL
HHHEECCCCEEEEEECCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
GDRQPSTIVKFGLGLMLTGASYLIMTLPGLLNGTSGRASALWLVLMFAVQMAGELLVSPV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPIFKAATEVHFFAITGIIGIIVGI
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILLIIKKPILKLMGDVR
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQ
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
AMAIVSIYGALVYLSTIVGGWVADRLLGASRTIFLGGILITLGHVALATPFGLSSLFVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGINMGSLIAPLIVGTVGQGVNY
HHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCE
HLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDAKAKRNFIITLTIVLIVALIGF
EHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHH
FLIYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
FWAIEEQSSTIIAVWGESRSNLNPTWFGFTFHIDPSWYQLLNPLFIVLLSPIFVRIWNKL
HHHEECCCCEEEEEECCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
GDRQPSTIVKFGLGLMLTGASYLIMTLPGLLNGTSGRASALWLVLMFAVQMAGELLVSPV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPIFKAATEVHFFAITGIIGIIVGI
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILLIIKKPILKLMGDVR
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]