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The map label for this gene is rliC [H]

Identifier: 125624624

GI number: 125624624

Start: 1815995

End: 1816984

Strand: Reverse

Name: rliC [H]

Synonym: llmg_1835

Alternate gene names: 125624624

Gene position: 1816984-1815995 (Counterclockwise)

Preceding gene: 125624625

Following gene: 125624616

Centisome position: 71.83

GC content: 34.04

Gene sequence:

>990_bases
ATGACAAAAATCACTTTAAAAGAAATTGCGACAATGGCTGATGTATCAGTGATGACGGTCTCTAATGTTATCCGTGGGAA
AGATTCACGCGTTTCGGCTGAGACAAAAGCTAAAATTCAAGCTTTAGTGAAAAAGTATAATTATGTTCCCAACCAAAATG
CAGCCAATTTACGTTCAGGAAAATCGAAATTAATCGGTGTCTTATTTTATAATAAATCTCAAAACATAGATTTTACCGAC
CCTTTTATTTCTTCAGTTTTAACTGGAATTGAGCGAAGAGCGAAGGAGGAGGGTTATTTTACAATGGTTCATACCGTCCA
AAATGCAAAGGGAATTGAGCAGCTTCAAAGAAACTGGGCTTTCGCTGGTTTTATTGTGGTCGGGGTATCAAATAAAGACT
TTTTGCAAATTGATCAAGCGATATTAACTCCAGTCAGTTATATAGATACCTATTTTGAAGATACAAAAAAATTAGATGAT
AAGTTAAGAAATTTTATTGGCACCAATGAGGAAAAAATTTCAGAAAGTATTGCTAATCATCTCACAGAAATGGGGCATGA
AGAAGTTCTATTTTATAGTTTTGACTTTAATCAAGAAGAACCAAGTGTTATTGAAAAACGTTATCATGCTTTTCATAAAT
TTTTTAAGGGCGAAATTTTGTTTGCAACGACAAAAAGCGCAGACTACCAGGAAATTTTGAAGAGTGTGTCAGTTTATTTG
ATGGAGCAGCCTTTTACGGCAATTTATGCTACTGCTGATATTTTGGCAGCAAAGTTAAATCAAATTTTTAAAGAGATTTC
GATAGTAGGAGTTGATGATGCAGAATTTGATGAATTTATCTCGCCTAAATTGACAACAGTAGCCATTAACCAAGTTGAAA
AGGGAAATGTGGCAATGGGAAGTTTGATTAATTCAATTGAGAAAGAAATTTCTGAAAATTACTCTTCGGAAAGCCTCCTA
ATCATTCGGGATAGCGTAAAAAAACTCTGA

Upstream 100 bases:

>100_bases
ACAGTGGAAAATAAAGAGGAAGCTTTGTATAATAGGATGACAGAGGTTCTGAAAACTTAAACATATAGGTGAATGCTTCC
TCTTGTTAGAAACGAAGACT

Downstream 100 bases:

>100_bases
CTATTTGTCAGAGTTTTTTTTGTGGGACCAAGGCGTTGACCACTGTGATTTGAGAAATGATAGTTTCATTTTCGTCAGTG
ATTTTGATTTCCCAAACGTG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTKITLKEIATMADVSVMTVSNVIRGKDSRVSAETKAKIQALVKKYNYVPNQNAANLRSGKSKLIGVLFYNKSQNIDFTD
PFISSVLTGIERRAKEEGYFTMVHTVQNAKGIEQLQRNWAFAGFIVVGVSNKDFLQIDQAILTPVSYIDTYFEDTKKLDD
KLRNFIGTNEEKISESIANHLTEMGHEEVLFYSFDFNQEEPSVIEKRYHAFHKFFKGEILFATTKSADYQEILKSVSVYL
MEQPFTAIYATADILAAKLNQIFKEISIVGVDDAEFDEFISPKLTTVAINQVEKGNVAMGSLINSIEKEISENYSSESLL
IIRDSVKKL

Sequences:

>Translated_329_residues
MTKITLKEIATMADVSVMTVSNVIRGKDSRVSAETKAKIQALVKKYNYVPNQNAANLRSGKSKLIGVLFYNKSQNIDFTD
PFISSVLTGIERRAKEEGYFTMVHTVQNAKGIEQLQRNWAFAGFIVVGVSNKDFLQIDQAILTPVSYIDTYFEDTKKLDD
KLRNFIGTNEEKISESIANHLTEMGHEEVLFYSFDFNQEEPSVIEKRYHAFHKFFKGEILFATTKSADYQEILKSVSVYL
MEQPFTAIYATADILAAKLNQIFKEISIVGVDDAEFDEFISPKLTTVAINQVEKGNVAMGSLINSIEKEISENYSSESLL
IIRDSVKKL
>Mature_328_residues
TKITLKEIATMADVSVMTVSNVIRGKDSRVSAETKAKIQALVKKYNYVPNQNAANLRSGKSKLIGVLFYNKSQNIDFTDP
FISSVLTGIERRAKEEGYFTMVHTVQNAKGIEQLQRNWAFAGFIVVGVSNKDFLQIDQAILTPVSYIDTYFEDTKKLDDK
LRNFIGTNEEKISESIANHLTEMGHEEVLFYSFDFNQEEPSVIEKRYHAFHKFFKGEILFATTKSADYQEILKSVSVYLM
EQPFTAIYATADILAAKLNQIFKEISIVGVDDAEFDEFISPKLTTVAINQVEKGNVAMGSLINSIEKEISENYSSESLLI
IRDSVKKL

Specific function: This Protein Negatively Controls The Transcription Initiation Of Genes Such As Deocabd, Udp, And Cdd Encoding Catabolizing Enzymes And Nupc, Nupg, And Tsx Encoding Transporting And Pore-Forming Proteins. Binds Cytidine And Adenosine As Effectors. [C]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=326, Percent_Identity=24.8466257668712, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786540, Length=311, Percent_Identity=25.4019292604502, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789202, Length=307, Percent_Identity=24.1042345276873, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787906, Length=199, Percent_Identity=27.6381909547739, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37159; Mature: 37028

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKITLKEIATMADVSVMTVSNVIRGKDSRVSAETKAKIQALVKKYNYVPNQNAANLRSG
CCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCC
KSKLIGVLFYNKSQNIDFTDPFISSVLTGIERRAKEEGYFTMVHTVQNAKGIEQLQRNWA
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCC
FAGFIVVGVSNKDFLQIDQAILTPVSYIDTYFEDTKKLDDKLRNFIGTNEEKISESIANH
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LTEMGHEEVLFYSFDFNQEEPSVIEKRYHAFHKFFKGEILFATTKSADYQEILKSVSVYL
HHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
MEQPFTAIYATADILAAKLNQIFKEISIVGVDDAEFDEFISPKLTTVAINQVEKGNVAMG
HHCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHCCCCEEEEEECCCCCCCHHHH
SLINSIEKEISENYSSESLLIIRDSVKKL
HHHHHHHHHHHHCCCCCEEEEEECCHHCC
>Mature Secondary Structure 
TKITLKEIATMADVSVMTVSNVIRGKDSRVSAETKAKIQALVKKYNYVPNQNAANLRSG
CEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCC
KSKLIGVLFYNKSQNIDFTDPFISSVLTGIERRAKEEGYFTMVHTVQNAKGIEQLQRNWA
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCC
FAGFIVVGVSNKDFLQIDQAILTPVSYIDTYFEDTKKLDDKLRNFIGTNEEKISESIANH
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LTEMGHEEVLFYSFDFNQEEPSVIEKRYHAFHKFFKGEILFATTKSADYQEILKSVSVYL
HHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
MEQPFTAIYATADILAAKLNQIFKEISIVGVDDAEFDEFISPKLTTVAINQVEKGNVAMG
HHCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHCCCCEEEEEECCCCCCCHHHH
SLINSIEKEISENYSSESLLIIRDSVKKL
HHHHHHHHHHHHCCCCCEEEEEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]