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The map label for this gene is engA [H]

Identifier: 125624594

GI number: 125624594

Start: 1786335

End: 1787645

Strand: Reverse

Name: engA [H]

Synonym: llmg_1805

Alternate gene names: 125624594

Gene position: 1787645-1786335 (Counterclockwise)

Preceding gene: 125624595

Following gene: 125624593

Centisome position: 70.67

GC content: 39.51

Gene sequence:

>1311_bases
ATGAGCTTACCTACAGTCGCCATCGTTGGGCGTCCAAATGTTGGAAAATCAACGATATTCAACCGTATTGCAGGAGAACG
CATCTCAATTGTCGAAGACATTCCAGGTGTAACTCGTGACCGTATCTATGCCACAGGAGAATGGTTAACCCGTAAATTCA
ACATCATCGACACCGGTGGGATTGAACTTTCAGATGAACCTTTCATGACTGAAATTCGGGCACAGGCCGAAATCGCCATG
ACCGAAGCAGATGTTATTATCGCTGTCGTTGATGGAGAAACAGGAATTACTGATGCCGATGAAGCAGTTGCTAATATTCT
TTATCGTACAGATAAACCTGTCATTCTTATCGTCAATAAAGTCGACAACCCGGAACGTCGAATGGAAATTTTTGACTTCT
ATTCACTTGGACTCGGCGATCCATATCCTGTATCAGCTGTTCACGGGATTGGGACAGGGGATGTACTTGATGCTATTGTT
CAAAATCTTCCTAATGAAATCGAAGAAGAAAATGAAGATGTCATCAAGTTCAGCTTGATTGGTCGTCCAAACGTTGGTAA
ATCATCTCTTATCAATGCCATTCTTGGTGAAGACCGAGTGATTGCAAGCCCAATCGCGGGAACAACTCGTGATGCCATTG
ATACACACTTCGTTGATTCTGAAGACCAAGAATTTGTCATGATTGATACCGCTGGAATGCGTAAATCAGGAAAAATTTAC
GAAAACACTGAAAAATATTCAGTTATGCGTGCCATGCGTGCCATTGACCGTTCAGATATCGTTTTGATGGTCATTAATGC
TGAAGAAGGAATTCGCGAATATGATATGCGTATCGCTGGATTTGCTCATGAAGCAGGTAAAGGGATTCTGATTGTTGTCA
ATAAATGGGATACTCTTGAAAAAGACAATGATACAATGAAAAAATTTGAATTAGAAATTCGTACAAAGTTCAAATTCCTT
GATTATGCACCAATCGTTTACGTGTCTGCTAAAACTGGCCAACGATTGAATAAACTTCCAGATATGATTAAAGAAATTCA
CCATGCTCAAAACCTACGTATTTCAAGTTCTGTTTTGAATGATGTGATTATGGATGCCGTTGCGATTAATCCAACTCCGA
CAGATAAAGGAAAACGTTTGAAGATTTTCTATGCAACACAAGTTGCCATTAAACCACCAACTTTTGTTGTTTTTGTCAAC
GAAGAAGAACTGATGCACTTCTCATATCTTCGTTTCTTGGAAAATCAAATTCGTAAAGCCTTTGTTTTTGAAGGAACTCC
GATTCATTTGATTGCTCGTAAACGTAAATAA

Upstream 100 bases:

>100_bases
GAACTGAACTATAAAATTATATAGCCTTTAGATTACAACATCTTTAGCTTAACTATCATAATTTTTCAAACAATAAGTAA
ACAAAGAAAGAAATAAAAAT

Downstream 100 bases:

>100_bases
TTAAAAACACTGATTATTCAGTGCTTTTTTTATGCAAAAGAATTGCAAAAATCCTGAATTTGAAATATACTATTAAAAAA
TTAGTTTAAGCGAAAGAAGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGGIELSDEPFMTEIRAQAEIAM
TEADVIIAVVDGETGITDADEAVANILYRTDKPVILIVNKVDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIV
QNLPNEIEEENEDVIKFSLIGRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIY
ENTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLEKDNDTMKKFELEIRTKFKFL
DYAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLNDVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVN
EEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK

Sequences:

>Translated_436_residues
MSLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGGIELSDEPFMTEIRAQAEIAM
TEADVIIAVVDGETGITDADEAVANILYRTDKPVILIVNKVDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIV
QNLPNEIEEENEDVIKFSLIGRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIY
ENTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLEKDNDTMKKFELEIRTKFKFL
DYAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLNDVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVN
EEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK
>Mature_435_residues
SLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGGIELSDEPFMTEIRAQAEIAMT
EADVIIAVVDGETGITDADEAVANILYRTDKPVILIVNKVDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIVQ
NLPNEIEEENEDVIKFSLIGRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIYE
NTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLEKDNDTMKKFELEIRTKFKFLD
YAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLNDVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVNE
EELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=457, Percent_Identity=37.855579868709, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1788919, Length=176, Percent_Identity=32.3863636363636, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=37.6344086021505, Blast_Score=65, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=173, Percent_Identity=34.1040462427746, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48910; Mature: 48779

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGG
CCCCEEEEEECCCCCHHHHHHHHCCCEEEHHHHCCCCCHHCEEECCHHHEEEEEEEECCC
IELSDEPFMTEIRAQAEIAMTEADVIIAVVDGETGITDADEAVANILYRTDKPVILIVNK
CEECCCCHHHHHHHHHEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIVQNLPNEIEEENEDVIKFSLI
CCCHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHHCCHHHHCCCCCEEEEEEE
GRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIY
CCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCEE
ENTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLE
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHEEEHHHCCCEEEEEEECCCCCC
KDNDTMKKFELEIRTKFKFLDYAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLN
CCCCCHHHEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEHHHHHH
DVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVNEEELMHFSYLRFLENQIRKA
HHHHHHEECCCCCCCCCCEEEEEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHE
FVFEGTPIHLIARKRK
EEECCCCEEEEEECCC
>Mature Secondary Structure 
SLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGG
CCCEEEEEECCCCCHHHHHHHHCCCEEEHHHHCCCCCHHCEEECCHHHEEEEEEEECCC
IELSDEPFMTEIRAQAEIAMTEADVIIAVVDGETGITDADEAVANILYRTDKPVILIVNK
CEECCCCHHHHHHHHHEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIVQNLPNEIEEENEDVIKFSLI
CCCHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHHCCHHHHCCCCCEEEEEEE
GRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIY
CCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCEE
ENTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLE
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHEEEHHHCCCEEEEEEECCCCCC
KDNDTMKKFELEIRTKFKFLDYAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLN
CCCCCHHHEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEHHHHHH
DVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVNEEELMHFSYLRFLENQIRKA
HHHHHHEECCCCCCCCCCEEEEEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHE
FVFEGTPIHLIARKRK
EEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]