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The map label for this gene is fabH [H]

Identifier: 125624577

GI number: 125624577

Start: 1766945

End: 1767922

Strand: Reverse

Name: fabH [H]

Synonym: llmg_1787

Alternate gene names: 125624577

Gene position: 1767922-1766945 (Counterclockwise)

Preceding gene: 125624578

Following gene: 125624576

Centisome position: 69.89

GC content: 39.47

Gene sequence:

>978_bases
ATGACTTTTGCGAAAATCACGCAAGCGGCACATTATGTGCCAGAAAACGTAGTATCTAATGATGACTTATCAAAAATTAT
GGATACTAATGATGAATGGATTTACAGTCGAACAGGAATTAAAAATCGTCATATTTCAACTGGGGAAAATACTTCAGATT
TAGCAACAAAAGTTGCTAAACAGTTGATTGAAAATTCTGGGGTAGACCCAGAATTGATAGATTTTATTATTGTTGCTACT
GTGACCCCTGATTCAATGATGCCCTCAACAGCCGCACGCGTTCAAGCGCAAGTAGGTGCAACTAATGCATTTGCTTACGA
CCTGACCGCGGCATGCTCAGGATTTGTTTTTGCACTATCAACCGCAGAAAAATTAATTTCCTCAGGTGCTTATCAACGTG
GGATTGTCATTGGAGCAGAAGTATTCTCAAAAGTAATTGACTGGTCAGACCGGTCAACAGCCGTTCTTTTTGGAGATGGC
GCTGCTGGTGTACTCTTGGACAATAGTGGAAGTCAACCTCTTATTATTGCTGAAAAAATGCAGACAGATGGCAAGCGAGG
TGGAAGTTTACTTTCTAGCTACGCTGATATTCAAACGCCTTTTGCCTCTGTTTCATACGAGGGTTCAAACTTGAGTATGG
AAGGGCGAGCAATTTTTGATTTTGCTGTACGCGATGTTCCAAAGAACATTCAAGCAACATTAGAAAAATCTGACCTTGCT
GCTGAAGAAATAGATTATTATCTCCTTCATCAAGCAAATTCAAGAATTCTTGATAAAATGGCTAAAAAGTTAGGCGTGAC
AAGGGATAAGTTCCTCCAAAATATGCAAGAATATGGCAATACATCGGCAGCAAGTATCCCTATATTGTTGTCAGAATCTG
TAAAAAATGGTATATTTAGTTTGGACGGTCAAACAAAAGTCGTCTTGACAGGATTTGGTGGTGGCCTCACTTGGGGCACA
GCAATTATTAATTTATAA

Upstream 100 bases:

>100_bases
TGATTACTGACAATCTATTTGATAGTGTTTATGGAACAACTGAAAACAAGCTAGCTGGTGAACTTGCAGCTCTGCATAAT
TCTTTGGAGAATATGAAATA

Downstream 100 bases:

>100_bases
GAGTCAAAAAGTTTAGCCTACTTTTGGTAAGTTGTCTACTTTAAATTTAAAAAAATGACGAAAAAGTTGAAGCTGACTTA
ACTCTTAAGTAGATTTTAAA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTFAKITQAAHYVPENVVSNDDLSKIMDTNDEWIYSRTGIKNRHISTGENTSDLATKVAKQLIENSGVDPELIDFIIVAT
VTPDSMMPSTAARVQAQVGATNAFAYDLTAACSGFVFALSTAEKLISSGAYQRGIVIGAEVFSKVIDWSDRSTAVLFGDG
AAGVLLDNSGSQPLIIAEKMQTDGKRGGSLLSSYADIQTPFASVSYEGSNLSMEGRAIFDFAVRDVPKNIQATLEKSDLA
AEEIDYYLLHQANSRILDKMAKKLGVTRDKFLQNMQEYGNTSAASIPILLSESVKNGIFSLDGQTKVVLTGFGGGLTWGT
AIINL

Sequences:

>Translated_325_residues
MTFAKITQAAHYVPENVVSNDDLSKIMDTNDEWIYSRTGIKNRHISTGENTSDLATKVAKQLIENSGVDPELIDFIIVAT
VTPDSMMPSTAARVQAQVGATNAFAYDLTAACSGFVFALSTAEKLISSGAYQRGIVIGAEVFSKVIDWSDRSTAVLFGDG
AAGVLLDNSGSQPLIIAEKMQTDGKRGGSLLSSYADIQTPFASVSYEGSNLSMEGRAIFDFAVRDVPKNIQATLEKSDLA
AEEIDYYLLHQANSRILDKMAKKLGVTRDKFLQNMQEYGNTSAASIPILLSESVKNGIFSLDGQTKVVLTGFGGGLTWGT
AIINL
>Mature_324_residues
TFAKITQAAHYVPENVVSNDDLSKIMDTNDEWIYSRTGIKNRHISTGENTSDLATKVAKQLIENSGVDPELIDFIIVATV
TPDSMMPSTAARVQAQVGATNAFAYDLTAACSGFVFALSTAEKLISSGAYQRGIVIGAEVFSKVIDWSDRSTAVLFGDGA
AGVLLDNSGSQPLIIAEKMQTDGKRGGSLLSSYADIQTPFASVSYEGSNLSMEGRAIFDFAVRDVPKNIQATLEKSDLAA
EEIDYYLLHQANSRILDKMAKKLGVTRDKFLQNMQEYGNTSAASIPILLSESVKNGIFSLDGQTKVVLTGFGGGLTWGTA
IINL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=324, Percent_Identity=38.2716049382716, Blast_Score=235, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34877; Mature: 34746

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAKITQAAHYVPENVVSNDDLSKIMDTNDEWIYSRTGIKNRHISTGENTSDLATKVAK
CCHHHHHHHHHHCCHHHCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHH
QLIENSGVDPELIDFIIVATVTPDSMMPSTAARVQAQVGATNAFAYDLTAACSGFVFALS
HHHHCCCCCHHHEEEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
TAEKLISSGAYQRGIVIGAEVFSKVIDWSDRSTAVLFGDGAAGVLLDNSGSQPLIIAEKM
HHHHHHHCCCHHCCEEEHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCEEEEHHH
QTDGKRGGSLLSSYADIQTPFASVSYEGSNLSMEGRAIFDFAVRDVPKNIQATLEKSDLA
HCCCCCCHHHHHHHHHHCCCHHHEEECCCCCCCCCCEEEHHHHHHCCHHHHHHHHHHHCH
AEEIDYYLLHQANSRILDKMAKKLGVTRDKFLQNMQEYGNTSAASIPILLSESVKNGIFS
HHHHHHHEEHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCEEE
LDGQTKVVLTGFGGGLTWGTAIINL
ECCCEEEEEEECCCCHHHHHHEECC
>Mature Secondary Structure 
TFAKITQAAHYVPENVVSNDDLSKIMDTNDEWIYSRTGIKNRHISTGENTSDLATKVAK
CHHHHHHHHHHCCHHHCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHH
QLIENSGVDPELIDFIIVATVTPDSMMPSTAARVQAQVGATNAFAYDLTAACSGFVFALS
HHHHCCCCCHHHEEEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
TAEKLISSGAYQRGIVIGAEVFSKVIDWSDRSTAVLFGDGAAGVLLDNSGSQPLIIAEKM
HHHHHHHCCCHHCCEEEHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCEEEEHHH
QTDGKRGGSLLSSYADIQTPFASVSYEGSNLSMEGRAIFDFAVRDVPKNIQATLEKSDLA
HCCCCCCHHHHHHHHHHCCCHHHEEECCCCCCCCCCEEEHHHHHHCCHHHHHHHHHHHCH
AEEIDYYLLHQANSRILDKMAKKLGVTRDKFLQNMQEYGNTSAASIPILLSESVKNGIFS
HHHHHHHEEHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCEEE
LDGQTKVVLTGFGGGLTWGTAIINL
ECCCEEEEEEECCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]