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The map label for this gene is argC [H]

Identifier: 125624548

GI number: 125624548

Start: 1743705

End: 1744727

Strand: Reverse

Name: argC [H]

Synonym: llmg_1758

Alternate gene names: 125624548

Gene position: 1744727-1743705 (Counterclockwise)

Preceding gene: 125624549

Following gene: 125624547

Centisome position: 68.98

GC content: 34.12

Gene sequence:

>1023_bases
ATGAAAAAAGTAGCAATTGTCGGAATTAGAGGTTATAGCGGCTTAGAACTGTTCCGAATTTTCTATTATCATCCAGAAGT
AGAAGTAACAAAAATATATGCAACAAGTCATTATGGAGAAAAATTATCAGAACGCTTTCCGCAACTTGAAGGCTTGACTG
ACTTGACTATTAGTGAATTTAATGAAGAAGAAATTATGGCAGAATGTGATGCGGTTTTCTTTGCAACCTCAGCGGGTGTT
AGTCAAAAATTAGCTTTAACTTTTATTGATAATAATTTTCCTGTAATTGATTTATCAGGAGATTTTCGATTAGCTGATTT
AGAAATATACAATAAATGGTATAAAAATACAAATTTAAAAAATGAATATTTATTAAGTGCTCAATATAATCTGGCAGACA
TTGGTCAAGCAAAAGCAAACTATATCGCGAATCCAGGTTGCTATGCAACAGCCACACTACTTGCACTTTATCCGTTAGTT
AAAAATAAGATGATTGATTTAGACTCAATCATTGTGGATGCCAAGTCAGGACTTTCGGGATCCGGAAAAGGTCTGTCTGA
CTCGAGCCATTTTGTGAATGTTGTCGATAATATGTCCATGTATAAAATCAATAGTCATCAACATATTCCAGAAATTGCTC
AACAATTGAAGATTTGGAATTCAAATTTTCAAGCCTTGCAATTTTCAACTTCTTTAATTCCTGTGAGTCGAGGGATTTTT
GTTAGTAGCTATGCAAAAGTTGCAGCTGATTTTGATTTTGAAACGATAAAAAATGCTTATGAACAGGTCTATGCGACAAA
AAACTTTGTCAGAATTCGACGACAAATGCCCCAACTCTCAGATGTGATTGGGACCAATTTTTGCGATATTGGATTAGCTT
ATAATCCAGTGACAAATGTTTTGTCAGTTGTTTCGGTGATTGACAATCTTATGAAAGGTGCTGCCGGACAAGCAGTACAA
AATTTTAATCAGTTATTTGGCTACGATGAAAGTTTAGGCTTGAAATTTATGCCAAGTCTTTAG

Upstream 100 bases:

>100_bases
TCTCTTTTTTTGTTTAAAAAAGTATAATAATACATAAAATTCTTGACAAATAAAAAATAGAGTAGTATAGTGTATAAAAA
TACATAGAAAGTGTGTAAAT

Downstream 100 bases:

>100_bases
AAGAGGAAGAAATGAAAGAAATAAAAGGGACAATTGCAAGTCCAAAGGGATTTTTGGCAGATGCTGTTCATGCACAATTA
AAATATAAAAACTTAGATTT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSERFPQLEGLTDLTISEFNEEEIMAECDAVFFATSAGV
SQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLKNEYLLSAQYNLADIGQAKANYIANPGCYATATLLALYPLV
KNKMIDLDSIIVDAKSGLSGSGKGLSDSSHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPQLSDVIGTNFCDIGLAYNPVTNVLSVVSVIDNLMKGAAGQAVQ
NFNQLFGYDESLGLKFMPSL

Sequences:

>Translated_340_residues
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSERFPQLEGLTDLTISEFNEEEIMAECDAVFFATSAGV
SQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLKNEYLLSAQYNLADIGQAKANYIANPGCYATATLLALYPLV
KNKMIDLDSIIVDAKSGLSGSGKGLSDSSHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPQLSDVIGTNFCDIGLAYNPVTNVLSVVSVIDNLMKGAAGQAVQ
NFNQLFGYDESLGLKFMPSL
>Mature_340_residues
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSERFPQLEGLTDLTISEFNEEEIMAECDAVFFATSAGV
SQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLKNEYLLSAQYNLADIGQAKANYIANPGCYATATLLALYPLV
KNKMIDLDSIIVDAKSGLSGSGKGLSDSSHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPQLSDVIGTNFCDIGLAYNPVTNVLSVVSVIDNLMKGAAGQAVQ
NFNQLFGYDESLGLKFMPSL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=343, Percent_Identity=36.1516034985423, Blast_Score=181, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6320913, Length=353, Percent_Identity=27.1954674220963, Blast_Score=93, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 37955; Mature: 37955

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSERFPQLEGLTDLTISEF
CCCEEEEEECCCCCCEEEEEEEECCCEEEEEEEEECHHHHHHHHHCCHHCCCCCCHHHHC
NEEEIMAECDAVFFATSAGVSQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLK
CHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCEEEECCCEEEEHHHHHHHHHHCCCCC
NEYLLSAQYNLADIGQAKANYIANPGCYATATLLALYPLVKNKMIDLDSIIVDAKSGLSG
CEEEEEECCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCC
SGKGLSDSSHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
CCCCCCCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCEEECCCCCH
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPQLSDVIGTNFCDIGLAYNPVTNV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEECCCCCCHHHHH
LSVVSVIDNLMKGAAGQAVQNFNQLFGYDESLGLKFMPSL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCC
>Mature Secondary Structure
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSERFPQLEGLTDLTISEF
CCCEEEEEECCCCCCEEEEEEEECCCEEEEEEEEECHHHHHHHHHCCHHCCCCCCHHHHC
NEEEIMAECDAVFFATSAGVSQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLK
CHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCEEEECCCEEEEHHHHHHHHHHCCCCC
NEYLLSAQYNLADIGQAKANYIANPGCYATATLLALYPLVKNKMIDLDSIIVDAKSGLSG
CEEEEEECCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCC
SGKGLSDSSHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
CCCCCCCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCEEECCCCCH
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPQLSDVIGTNFCDIGLAYNPVTNV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEECCCCCCHHHHH
LSVVSVIDNLMKGAAGQAVQNFNQLFGYDESLGLKFMPSL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]