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The map label for this gene is argD [H]

Identifier: 125624546

GI number: 125624546

Start: 1741357

End: 1742490

Strand: Reverse

Name: argD [H]

Synonym: llmg_1756

Alternate gene names: 125624546

Gene position: 1742490-1741357 (Counterclockwise)

Preceding gene: 125624547

Following gene: 125624545

Centisome position: 68.89

GC content: 35.89

Gene sequence:

>1134_bases
ATGACAAATTTATTTGAAAATTATGGTCGCCTACCATTTAGCTTAATCAAAGGAGAAAATCAATATTTATTTGATGACAG
GGGAAATAAGTATTTAGATTTCACAAGTGGGATTGGGGTCATGAATTTAGGATATAGTTTTGAAAAGGAAAAAGTGGCGG
TGAAAGCTCAATTAGACAGCTTGTCTCATCTTTCAAATCTTTATCAAAATCCTTTGCAAGAAGATGTGGCTGAAAAGTTA
AGTCAAAATCATTCTTATAAAGCTTTTTTTTGTAATTCTGGGACTGAAGCTAATGAAGCAGCTTTAAAATTAACTCATCT
CATCAAAAAAGATCAGAAAATTTTGGCGTTTACAGATGGCTTTCATGGTCGTACTTTTGGCGCTATGAGTGCTACCATGC
AAGAAAAAATCCAAGCAGGATTTTCGCCTTTATTACCAAATTTTGTGGCTAGTCCTTTTAATGATGTGGTAGCACTTGAG
CAAATCCTTGAAAAAGAAAAAATTGGCGCGATTATTTTTGAAATTATTCAGGGTGAGGGTGGCGTTTTACCAATTTCTCC
AGATTTTGTTGAAGCTCTAAAAACTTGTCAGCAAAAAGGAATTTTACTGATTATTGATGAAGTTCAAACTGGAATTGGTC
GAACTGGAAAATTATTTGCTTTTGAACATTTTGATTTTGAGCCGGATATTTTTACTTTGGCAAAAGCATTGGCGAATGGG
ATTCCTACAGGTGCGATGCTCGCTAGGAATAAATATGCCAGTTATTTTTCAGCAGGAAAGCATGGCTCAACATTTGGTGG
GAATCCTTTAGCCATGGCTTCGGCTAATGAAGTTTTAAAAGAAATTGACAGTGAGTTTTTAGAAAAAGTGACTGTCAAAG
GCATTTTTTTCTTAAAATTACTGACAGAAAATCTGTCAGTAAAAGCGACGGTTAAGTCCATCAGAGGTTTGGGATTGATG
ATTGGAATTCAATTAACTGACGATAAAAAAGTTCCAGAAGTTCTTGCTTTACTGCGTGGAAATGGTCTCTTAGCCTTGTC
AGCTGGTCATGATGTCATTCGCTTACTCCCACCGCTTGTCATGACGAAAGAAGAACTGCAAAAAGGAGCAGAGCTATTGG
AGAAAATTTTATGA

Upstream 100 bases:

>100_bases
CTTGAATGCTGGAAGTGGCTTGGGTCAGGCTTGGGGCTGTGATTTGACTTATAAATATGTCGAAATTAATGCTTTATATA
CAAGTTAAGAAGGAGAAAAA

Downstream 100 bases:

>100_bases
GAGATTCACAAAACACAGCTCAGACTTTGACCGAAAGTCTCAAATATTTTCTGAAATATCGTGACCAAACGGTTGTCATT
AAATATGGTGGGAATGCGAT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTNLFENYGRLPFSLIKGENQYLFDDRGNKYLDFTSGIGVMNLGYSFEKEKVAVKAQLDSLSHLSNLYQNPLQEDVAEKL
SQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDGFHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALE
QILEKEKIGAIIFEIIQGEGGVLPISPDFVEALKTCQQKGILLIIDEVQTGIGRTGKLFAFEHFDFEPDIFTLAKALANG
IPTGAMLARNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSEFLEKVTVKGIFFLKLLTENLSVKATVKSIRGLGLM
IGIQLTDDKKVPEVLALLRGNGLLALSAGHDVIRLLPPLVMTKEELQKGAELLEKIL

Sequences:

>Translated_377_residues
MTNLFENYGRLPFSLIKGENQYLFDDRGNKYLDFTSGIGVMNLGYSFEKEKVAVKAQLDSLSHLSNLYQNPLQEDVAEKL
SQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDGFHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALE
QILEKEKIGAIIFEIIQGEGGVLPISPDFVEALKTCQQKGILLIIDEVQTGIGRTGKLFAFEHFDFEPDIFTLAKALANG
IPTGAMLARNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSEFLEKVTVKGIFFLKLLTENLSVKATVKSIRGLGLM
IGIQLTDDKKVPEVLALLRGNGLLALSAGHDVIRLLPPLVMTKEELQKGAELLEKIL
>Mature_376_residues
TNLFENYGRLPFSLIKGENQYLFDDRGNKYLDFTSGIGVMNLGYSFEKEKVAVKAQLDSLSHLSNLYQNPLQEDVAEKLS
QNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDGFHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALEQ
ILEKEKIGAIIFEIIQGEGGVLPISPDFVEALKTCQQKGILLIIDEVQTGIGRTGKLFAFEHFDFEPDIFTLAKALANGI
PTGAMLARNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSEFLEKVTVKGIFFLKLLTENLSVKATVKSIRGLGLMI
GIQLTDDKKVPEVLALLRGNGLLALSAGHDVIRLLPPLVMTKEELQKGAELLEKIL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=386, Percent_Identity=35.4922279792746, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=36.4548494983278, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=29.1764705882353, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=410, Percent_Identity=28.2926829268293, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=28.6407766990291, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=25.9803921568627, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI226442709, Length=351, Percent_Identity=29.0598290598291, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=25.8454106280193, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=25.8454106280193, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=25.8454106280193, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788044, Length=373, Percent_Identity=38.0697050938338, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1789759, Length=375, Percent_Identity=37.8666666666667, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=33.5012594458438, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI145693181, Length=380, Percent_Identity=34.4736842105263, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787560, Length=393, Percent_Identity=33.0788804071247, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1786991, Length=389, Percent_Identity=30.0771208226221, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1786349, Length=351, Percent_Identity=27.3504273504274, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=388, Percent_Identity=33.5051546391753, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI25144274, Length=380, Percent_Identity=30.2631578947368, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32564660, Length=420, Percent_Identity=30.4761904761905, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71992977, Length=422, Percent_Identity=28.1990521327014, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=429, Percent_Identity=26.5734265734266, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=197, Percent_Identity=27.4111675126904, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=39.2764857881137, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=34.7394540942928, Blast_Score=202, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6324386, Length=353, Percent_Identity=28.8951841359773, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=420, Percent_Identity=25.952380952381, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=34.5360824742268, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=29.4392523364486, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28574759, Length=415, Percent_Identity=29.1566265060241, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21356575, Length=402, Percent_Identity=28.8557213930348, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281366494, Length=276, Percent_Identity=31.1594202898551, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667139, Length=276, Percent_Identity=31.1594202898551, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667143, Length=276, Percent_Identity=31.1594202898551, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41355; Mature: 41224

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLFENYGRLPFSLIKGENQYLFDDRGNKYLDFTSGIGVMNLGYSFEKEKVAVKAQLDS
CCCCHHHHCCCCEEEECCCCCEEEECCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHH
LSHLSNLYQNPLQEDVAEKLSQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDG
HHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
FHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALEQILEKEKIGAIIFEIIQGEG
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVLPISPDFVEALKTCQQKGILLIIDEVQTGIGRTGKLFAFEHFDFEPDIFTLAKALANG
CEECCCHHHHHHHHHHHHCCEEEEEECHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCC
IPTGAMLARNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSEFLEKVTVKGIFFLKL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTENLSVKATVKSIRGLGLMIGIQLTDDKKVPEVLALLRGNGLLALSAGHDVIRLLPPLV
HHCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCHHHHHHCHHH
MTKEELQKGAELLEKIL
CCHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TNLFENYGRLPFSLIKGENQYLFDDRGNKYLDFTSGIGVMNLGYSFEKEKVAVKAQLDS
CCCHHHHCCCCEEEECCCCCEEEECCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHH
LSHLSNLYQNPLQEDVAEKLSQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDG
HHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
FHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALEQILEKEKIGAIIFEIIQGEG
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVLPISPDFVEALKTCQQKGILLIIDEVQTGIGRTGKLFAFEHFDFEPDIFTLAKALANG
CEECCCHHHHHHHHHHHHCCEEEEEECHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCC
IPTGAMLARNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSEFLEKVTVKGIFFLKL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTENLSVKATVKSIRGLGLMIGIQLTDDKKVPEVLALLRGNGLLALSAGHDVIRLLPPLV
HHCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCHHHHHHCHHH
MTKEELQKGAELLEKIL
CCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]