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The map label for this gene is argF [H]

Identifier: 125624544

GI number: 125624544

Start: 1739480

End: 1740481

Strand: Reverse

Name: argF [H]

Synonym: llmg_1754

Alternate gene names: 125624544

Gene position: 1740481-1739480 (Counterclockwise)

Preceding gene: 125624545

Following gene: 125624543

Centisome position: 68.81

GC content: 33.03

Gene sequence:

>1002_bases
ATGTTTCAAGGAAGAAGTTTTTTAAAAGAGATAGATTTTAGTAAAGATGAATTGTTATATCTGATTGATTTTGCAATTCA
TCTTAAAAAGTTAAAAAAAGAACATATTCAACATAAATATTTATTAGATAAAAATATTGCCCTTATTTTTGAAAAAACCT
CTACAAGAACAAGAGCAGCTTTTACAACAGCTGCTGTAGATTTGGGAGCACATCCTGAATTTTTAGGGCCAAATGATATT
CAGTTGGGCAAAAAAGAATCTATTTCAGATACAGCGAAAGTTTTGGGTTCAATGTTTGATGGCATTGAGTTTCGTGGGTT
TAAGCAAAGTGATGTGGAAATTCTCGCCAAAGATTCAGGTAGACCCGTTTGGAATGGATTGACTGATGATTGGCATCCGA
CACAGATGCTGGCAGATTTTATGACAATCAAGGAGCATTTTGGCCATTTGCAAGATTTAACCCTCGCTTATGTTGGTGAT
GGACGAAATAATGTGGCAAATTCTCTATTAGTGACTGGAGCAATTTTAGGCGTAAATATCACAATTATTTCGCCCGAGTC
CTTGCAACCCGCTTTAGAAATACAAAAACTGGCACGTAAATATGCCATGAAAAGTCGCAGTAAAATAAGTATCCGAACAG
ATTTAAATGGACTTGAAAATGCTGATATTGTTTATACTGATGTTTGGGTCAGTATGGGTGAGGAAGCTCAAACAGCCAAG
CGAATTAAATTATTGAAATCCTATCAAATTAATCAAAAAGTTGTTGAAAAAATTATTAATAAAAACTTTATTTTTATGCA
TTGTTTACCCAGCTTTCATGATTTAAACACGGAAGTGATGAAAGAAATTAAGGAAAATTATAACCTTAATGAATTAGAGG
TTACTGATGAAGTTTTTAATTCAAAGAATTCGGTCGTTTTTGAACAAGCTGAAAATCGAATGCATACCATAAAAGCAGTC
ATGGCGGCTACTTTAGGAAATTTGTTTATTCCTAAAATATAA

Upstream 100 bases:

>100_bases
CGGTCGTGTTCCTCACGCCTTGTTATTGGAATTATTTACTGACAAAGGGCAAGGGACAATGATAAATCATTGATAATTTA
AGTAAATAAGAGGAGAGAGA

Downstream 100 bases:

>100_bases
AAAAAGAGAAAAAACGTTAATTAAGGGGGAATAGCCCAGATTTAATGTTTTTTCTCTTTTTTTTATGGCGCAAAAGTCCC
GTTCCACAGGGAAAGGCATA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MFQGRSFLKEIDFSKDELLYLIDFAIHLKKLKKEHIQHKYLLDKNIALIFEKTSTRTRAAFTTAAVDLGAHPEFLGPNDI
QLGKKESISDTAKVLGSMFDGIEFRGFKQSDVEILAKDSGRPVWNGLTDDWHPTQMLADFMTIKEHFGHLQDLTLAYVGD
GRNNVANSLLVTGAILGVNITIISPESLQPALEIQKLARKYAMKSRSKISIRTDLNGLENADIVYTDVWVSMGEEAQTAK
RIKLLKSYQINQKVVEKIINKNFIFMHCLPSFHDLNTEVMKEIKENYNLNELEVTDEVFNSKNSVVFEQAENRMHTIKAV
MAATLGNLFIPKI

Sequences:

>Translated_333_residues
MFQGRSFLKEIDFSKDELLYLIDFAIHLKKLKKEHIQHKYLLDKNIALIFEKTSTRTRAAFTTAAVDLGAHPEFLGPNDI
QLGKKESISDTAKVLGSMFDGIEFRGFKQSDVEILAKDSGRPVWNGLTDDWHPTQMLADFMTIKEHFGHLQDLTLAYVGD
GRNNVANSLLVTGAILGVNITIISPESLQPALEIQKLARKYAMKSRSKISIRTDLNGLENADIVYTDVWVSMGEEAQTAK
RIKLLKSYQINQKVVEKIINKNFIFMHCLPSFHDLNTEVMKEIKENYNLNELEVTDEVFNSKNSVVFEQAENRMHTIKAV
MAATLGNLFIPKI
>Mature_333_residues
MFQGRSFLKEIDFSKDELLYLIDFAIHLKKLKKEHIQHKYLLDKNIALIFEKTSTRTRAAFTTAAVDLGAHPEFLGPNDI
QLGKKESISDTAKVLGSMFDGIEFRGFKQSDVEILAKDSGRPVWNGLTDDWHPTQMLADFMTIKEHFGHLQDLTLAYVGD
GRNNVANSLLVTGAILGVNITIISPESLQPALEIQKLARKYAMKSRSKISIRTDLNGLENADIVYTDVWVSMGEEAQTAK
RIKLLKSYQINQKVVEKIINKNFIFMHCLPSFHDLNTEVMKEIKENYNLNELEVTDEVFNSKNSVVFEQAENRMHTIKAV
MAATLGNLFIPKI

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=334, Percent_Identity=37.125748502994, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI18105007, Length=325, Percent_Identity=24.3076923076923, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1790703, Length=329, Percent_Identity=48.6322188449848, Blast_Score=317, Evalue=5e-88,
Organism=Escherichia coli, GI1786469, Length=327, Percent_Identity=48.6238532110092, Blast_Score=314, Evalue=5e-87,
Organism=Escherichia coli, GI48994908, Length=369, Percent_Identity=24.390243902439, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI2367364, Length=153, Percent_Identity=37.2549019607843, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=328, Percent_Identity=36.890243902439, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6322331, Length=281, Percent_Identity=25.9786476868327, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642586, Length=332, Percent_Identity=25.9036144578313, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37779; Mature: 37779

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQGRSFLKEIDFSKDELLYLIDFAIHLKKLKKEHIQHKYLLDKNIALIFEKTSTRTRAA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
FTTAAVDLGAHPEFLGPNDIQLGKKESISDTAKVLGSMFDGIEFRGFKQSDVEILAKDSG
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCC
RPVWNGLTDDWHPTQMLADFMTIKEHFGHLQDLTLAYVGDGRNNVANSLLVTGAILGVNI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCEEEEECCCCHHHHHHHHHHHHEEEEEE
TIISPESLQPALEIQKLARKYAMKSRSKISIRTDLNGLENADIVYTDVWVSMGEEAQTAK
EEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEHHHHCCCHHHHHH
RIKLLKSYQINQKVVEKIINKNFIFMHCLPSFHDLNTEVMKEIKENYNLNELEVTDEVFN
HHHHHHHHCCCHHHHHHHHCCCEEEEEECCCHHCCCHHHHHHHHHCCCCCEEEECHHHHC
SKNSVVFEQAENRMHTIKAVMAATLGNLFIPKI
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFQGRSFLKEIDFSKDELLYLIDFAIHLKKLKKEHIQHKYLLDKNIALIFEKTSTRTRAA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
FTTAAVDLGAHPEFLGPNDIQLGKKESISDTAKVLGSMFDGIEFRGFKQSDVEILAKDSG
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCC
RPVWNGLTDDWHPTQMLADFMTIKEHFGHLQDLTLAYVGDGRNNVANSLLVTGAILGVNI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCEEEEECCCCHHHHHHHHHHHHEEEEEE
TIISPESLQPALEIQKLARKYAMKSRSKISIRTDLNGLENADIVYTDVWVSMGEEAQTAK
EEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEHHHHCCCHHHHHH
RIKLLKSYQINQKVVEKIINKNFIFMHCLPSFHDLNTEVMKEIKENYNLNELEVTDEVFN
HHHHHHHHCCCHHHHHHHHCCCEEEEEECCCHHCCCHHHHHHHHHCCCCCEEEECHHHHC
SKNSVVFEQAENRMHTIKAVMAATLGNLFIPKI
CCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]