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The map label for this gene is alr [H]

Identifier: 125624499

GI number: 125624499

Start: 1678978

End: 1680081

Strand: Reverse

Name: alr [H]

Synonym: llmg_1704

Alternate gene names: 125624499

Gene position: 1680081-1678978 (Counterclockwise)

Preceding gene: 125624500

Following gene: 125624498

Centisome position: 66.42

GC content: 36.87

Gene sequence:

>1104_bases
ATGAAAACTTCACCACATCGTAATACTTCAGCTATTGTTGATTTAAAAGCGATTAGAAATAATATTGAAAAATTTAAAAA
GCATATTAACCCTAATGCAGAGATTTGGCCAGCAGTGAAAGCAGATGCTTATGGTCATGGCTCGATTGAGGTTTCTAAAG
CGGTGAGCGATTTGGTAGGTGGTTTTTGTGTATCAAACCTAGATGAGGCAATTGAATTACGAAATCATCTGGTGACTAAA
CCGATTTTAGTTTTATCCGGAATTGTTCCAGAAGATGTTGATATTGCAGCTGCCCTTAATATTAGTCTTACTGCCCCGAG
TTTAGAATGGTTGAAATTGGTTGTTCAAGAAGAAGCAGAACTTTCAGATTTAAAAATTCATATTGGTGTAGATTCTGGTA
TGGGTCGGATTGGTATTCGTGATGTTGAAGAAGCTAATCAGATGATTGAACTTGCTGATAAATATGCGATTAATTTTGAA
GGAATTTTCACTCATTTTGCGACTGCGGATATGGCTGATGAAACAAAATTTAAAAATCAACAGGCAAGATTTAACAAAAT
TATGGCCGGATTATCACGTCAACCAAAATTTATACACTCAACTAATACGGCCGCTGCTTTATGGCATAAGGAACAAGTTC
AAGCTATTGAACGTTTAGGGATTTCAATGTATGGCTTGAATCCAAGTGGTAAAACTTTGGAACTTCCTTTTGAAATTGAA
CCCGCTCTCTCTTTAGTTTCTGAATTGACTCATATAAAAAAAATAGCTGCAGGTGAAACGGTTGGTTATGGTGCAACTTA
TGAGACGAGTGAAGAAACTTGGATTGGAACTGTTCCAATTGGTTACGCTGACGGGTGGACCCGTCAAATGCAAGGTTTCA
AAGTGCTTGTTGATGGAAAGTTTTGTGAGATTGTTGGTCGAGTTTGTATGGATCAAATGATGATAAAACTTGATAAGTCT
TACCCTTTGGGAACGAAGGTCACTTTGATTGGTCGAGATAAGGCTAATGAAATCACGACAACAGACGTTGCTGATTGGCG
TGGAACGATTAATTATGAAGTGCTTTGCTTACTTTCTGATAGAATCAAAAGAATCTATAAATAA

Upstream 100 bases:

>100_bases
TCTATTTCGCATAGTAATTTAGAAGCAGTTGCTTTTGTTGTTTTAGAAAAAAATTAAGAAGCAATAAAAATTTTGCTTAA
ACTAGAGAAAGGTTTAAAAG

Downstream 100 bases:

>100_bases
AATTAAAAAAACTGTATTTTTACAGTTTTTTTGTTTTCTGTTAAAAGCAGATGATAACCTCATTTTTATCTCATAAAAGC
CTTTACAAATTATCTTTTTA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKTSPHRNTSAIVDLKAIRNNIEKFKKHINPNAEIWPAVKADAYGHGSIEVSKAVSDLVGGFCVSNLDEAIELRNHLVTK
PILVLSGIVPEDVDIAAALNISLTAPSLEWLKLVVQEEAELSDLKIHIGVDSGMGRIGIRDVEEANQMIELADKYAINFE
GIFTHFATADMADETKFKNQQARFNKIMAGLSRQPKFIHSTNTAAALWHKEQVQAIERLGISMYGLNPSGKTLELPFEIE
PALSLVSELTHIKKIAAGETVGYGATYETSEETWIGTVPIGYADGWTRQMQGFKVLVDGKFCEIVGRVCMDQMMIKLDKS
YPLGTKVTLIGRDKANEITTTDVADWRGTINYEVLCLLSDRIKRIYK

Sequences:

>Translated_367_residues
MKTSPHRNTSAIVDLKAIRNNIEKFKKHINPNAEIWPAVKADAYGHGSIEVSKAVSDLVGGFCVSNLDEAIELRNHLVTK
PILVLSGIVPEDVDIAAALNISLTAPSLEWLKLVVQEEAELSDLKIHIGVDSGMGRIGIRDVEEANQMIELADKYAINFE
GIFTHFATADMADETKFKNQQARFNKIMAGLSRQPKFIHSTNTAAALWHKEQVQAIERLGISMYGLNPSGKTLELPFEIE
PALSLVSELTHIKKIAAGETVGYGATYETSEETWIGTVPIGYADGWTRQMQGFKVLVDGKFCEIVGRVCMDQMMIKLDKS
YPLGTKVTLIGRDKANEITTTDVADWRGTINYEVLCLLSDRIKRIYK
>Mature_367_residues
MKTSPHRNTSAIVDLKAIRNNIEKFKKHINPNAEIWPAVKADAYGHGSIEVSKAVSDLVGGFCVSNLDEAIELRNHLVTK
PILVLSGIVPEDVDIAAALNISLTAPSLEWLKLVVQEEAELSDLKIHIGVDSGMGRIGIRDVEEANQMIELADKYAINFE
GIFTHFATADMADETKFKNQQARFNKIMAGLSRQPKFIHSTNTAAALWHKEQVQAIERLGISMYGLNPSGKTLELPFEIE
PALSLVSELTHIKKIAAGETVGYGATYETSEETWIGTVPIGYADGWTRQMQGFKVLVDGKFCEIVGRVCMDQMMIKLDKS
YPLGTKVTLIGRDKANEITTTDVADWRGTINYEVLCLLSDRIKRIYK

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=361, Percent_Identity=33.2409972299169, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1790487, Length=371, Percent_Identity=30.188679245283, Blast_Score=145, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40677; Mature: 40677

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSPHRNTSAIVDLKAIRNNIEKFKKHINPNAEIWPAVKADAYGHGSIEVSKAVSDLVG
CCCCCCCCCHHEEEHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEHHHHHHHHHH
GFCVSNLDEAIELRNHLVTKPILVLSGIVPEDVDIAAALNISLTAPSLEWLKLVVQEEAE
HHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHCCC
LSDLKIHIGVDSGMGRIGIRDVEEANQMIELADKYAINFEGIFTHFATADMADETKFKNQ
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCHHHHHCHH
QARFNKIMAGLSRQPKFIHSTNTAAALWHKEQVQAIERLGISMYGLNPSGKTLELPFEIE
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECEECC
PALSLVSELTHIKKIAAGETVGYGATYETSEETWIGTVPIGYADGWTRQMQGFKVLVDGK
HHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEEECCCCCCCHHHHCCCCEEEECCH
FCEIVGRVCMDQMMIKLDKSYPLGTKVTLIGRDKANEITTTDVADWRGTINYEVLCLLSD
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCEEEEEEEHH
RIKRIYK
HHHHHCC
>Mature Secondary Structure
MKTSPHRNTSAIVDLKAIRNNIEKFKKHINPNAEIWPAVKADAYGHGSIEVSKAVSDLVG
CCCCCCCCCHHEEEHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEHHHHHHHHHH
GFCVSNLDEAIELRNHLVTKPILVLSGIVPEDVDIAAALNISLTAPSLEWLKLVVQEEAE
HHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHCCC
LSDLKIHIGVDSGMGRIGIRDVEEANQMIELADKYAINFEGIFTHFATADMADETKFKNQ
CCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCHHHHHCHH
QARFNKIMAGLSRQPKFIHSTNTAAALWHKEQVQAIERLGISMYGLNPSGKTLELPFEIE
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECEECC
PALSLVSELTHIKKIAAGETVGYGATYETSEETWIGTVPIGYADGWTRQMQGFKVLVDGK
HHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCEEEEECCCCCCCHHHHCCCCEEEECCH
FCEIVGRVCMDQMMIKLDKSYPLGTKVTLIGRDKANEITTTDVADWRGTINYEVLCLLSD
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEECCCCCCCCCCCEEEEEEEHH
RIKRIYK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]