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The map label for this gene is copB [H]

Identifier: 125624491

GI number: 125624491

Start: 1668937

End: 1670979

Strand: Direct

Name: copB [H]

Synonym: llmg_1694

Alternate gene names: 125624491

Gene position: 1668937-1670979 (Clockwise)

Preceding gene: 125624469

Following gene: 125624496

Centisome position: 65.98

GC content: 37.49

Gene sequence:

>2043_bases
ATGAAAAATGAAACTCATTCAGACGCTCATGAAAAAATGATGAACGAGCCTCATCATGATCACGAAATGATGCAGATGGA
AACTGATGGCCACGACATGGACATGATGAATCATGGTGGACACATGATGCACATGGGCGATATGAGTAAAAAGCTCAAAG
TTTCTATCGTTCTAATGATTCCGCTTCTACTCATTTCACCAATTGCTGGATTTACAATCCTTAAATTCCCTGGTAGTGAA
ATTCTCCAACTCATTCTCGGAACAATCATCTTCTTCTATTCTGGAACTCCTTTTTTCAGCGGGGCTAAAGGCGAACTAAA
AAGTCATAAGCCAGCCATGATGATGCTGATTACAATGGGAATTACCGTTGCCTATGCTTACTCAGTCTATGCCACAATCA
TGAGTCTTAATGGACAGATGGGAATGAACTTCTGGTTTGAACTTGCAACCTTAATTGTCATTATGCTGATTGGTCACCTC
ATTGAAATGAAAGCAATCATGGGTGCCGGTGATGCATTAAAAGACTTAGCAAGTCTTGTTCCTAAAAAAGCTCACTTAAA
AAATGGTGAAGATGTGGAACTTTCCGAATTAAAAGTTGGTGATTTACTTTTAGTAAAAGAAAATGAGAAAATACCTGCTG
ACGGAATAATTTTAGGTGAAGCCCTTATTGATGAATCTATGATTACTGGCGAAAGTCGGGCGATTAGCAAAAAAATGAAT
GCTTCTGTTTATGGTGGTTCACTGAACCAAAATCAACCTTTTGAAATGAAAGTCACAACACTTGGAAAGGATTCATTCCT
TAATCAGGTTGCCGAACTAGTCAAAAAAGCTCAATCCCAAAAATCTAATCTTGAAAATATGGCAGATAAGGTGGCTGGAT
ACCTCTTCTACGCTGCACTTATTGTCGGTATCTTTTCATTAATTTTTTGGACAATTAGTTCTAACTTTAGTTTTGCCTTA
CTTCTTGCGGTTTCTGTTTTTGTGATTGCATGTCCACATGCTTTAGGCCTTGCGGTTCCACTTGTCGTTTCACGCTTAAC
CAGTATTTCGGCTAAAAATGGCTTGCTTATTCAAAATAGAACTTCTTTAGAAAAAATCAATACGATTAAATATGCATTGA
TGGATAAAACAGGCACATTAACTGATGGTAAATTTGTCGTCCGTAATGTTATTGATTTTACTGATGATACGGACATTCTA
CAAATCATGGCAGCTCTTGAAGGAAGTTCTACTCATCCGATTGCTCAATCAATCGTTAATGCAGCTCAACCTCTGAAAAG
TCTAAAAGTTGAAGCAATTGAAAATATCCCTGGGGTTGGGATTAAAGGTCAAGTCAATCAACACTTTTATCAAATCGTTA
ATTATAAATATCTTCGCGAACATCAACTTTCTTATGATGAATCAAAAATTGCCCAATACTTAGAACTTGGGTTAACTGTA
TCCTTCTTAATCAATGACCAACAAAAGGTTTTAGGGTTCATCGCTTTAGGAGATACTCCAAAAGCTGATGCCAAAGATTT
TATAAACGGCCTGTTAGCTCAAGGAATCACACCCGTCATGTTAACAGGAGATAACAAGGAAACTGCTCAAAAAATTGCTA
CCGCACTAAATATTCCTGAATTTAGAGCGGAATTAAAGCCTGAAGATAAAGCAGAGATTGTGAAAGAATATCAGAAGAAA
GCAGGTGTTCTCTTCATTGGTGATGGTATCAATGATTCACCAGCACTTGCAACAGCTACGATTGGTTTTGCAATTGGCGC
AGGTACTTCCGTTGCCATTAACACTGCTGATGTTGTTCTAGTTAACTCCAATCCAAGTGACGTCTTAGATATGATAAATA
TCTCAAAAAGAATGCTTAAGAAAATGAAGCAAAACCTCTGGTTTGGGGCAGGTTATAATATTATTGCTATCCCTGTCGCA
GCAGGTATCCTTTATCCATTTACGGGGATTTATATTGACCCTCTTATTGCAGCAGTTCTTATGTCAATCTCAACTGTGAT
TGTTTCAATCAATGCGATGGGATTGAGGTATGATAAAAAATAG

Upstream 100 bases:

>100_bases
TCAGCTTTCTCAAAAAGATAATTCCTTGACATTTTAGGTTTACAATCGTAAACTTAATATAGAAAGACTAATCTCATACT
AAATCATTTGGGAGGAAAAT

Downstream 100 bases:

>100_bases
AAGAGCATATGCTCTTCTATTTTTTTATTTTTCAAGCCATAATTAAAATAAAATTTGATAGAAGCCTTTTATTATTTAAA
TATACTTAAACATTAAATAT

Product: copper-potassium transporting ATPase B

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MKNETHSDAHEKMMNEPHHDHEMMQMETDGHDMDMMNHGGHMMHMGDMSKKLKVSIVLMIPLLLISPIAGFTILKFPGSE
ILQLILGTIIFFYSGTPFFSGAKGELKSHKPAMMMLITMGITVAYAYSVYATIMSLNGQMGMNFWFELATLIVIMLIGHL
IEMKAIMGAGDALKDLASLVPKKAHLKNGEDVELSELKVGDLLLVKENEKIPADGIILGEALIDESMITGESRAISKKMN
ASVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQSQKSNLENMADKVAGYLFYAALIVGIFSLIFWTISSNFSFAL
LLAVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGKFVVRNVIDFTDDTDIL
QIMAALEGSSTHPIAQSIVNAAQPLKSLKVEAIENIPGVGIKGQVNQHFYQIVNYKYLREHQLSYDESKIAQYLELGLTV
SFLINDQQKVLGFIALGDTPKADAKDFINGLLAQGITPVMLTGDNKETAQKIATALNIPEFRAELKPEDKAEIVKEYQKK
AGVLFIGDGINDSPALATATIGFAIGAGTSVAINTADVVLVNSNPSDVLDMINISKRMLKKMKQNLWFGAGYNIIAIPVA
AGILYPFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDKK

Sequences:

>Translated_680_residues
MKNETHSDAHEKMMNEPHHDHEMMQMETDGHDMDMMNHGGHMMHMGDMSKKLKVSIVLMIPLLLISPIAGFTILKFPGSE
ILQLILGTIIFFYSGTPFFSGAKGELKSHKPAMMMLITMGITVAYAYSVYATIMSLNGQMGMNFWFELATLIVIMLIGHL
IEMKAIMGAGDALKDLASLVPKKAHLKNGEDVELSELKVGDLLLVKENEKIPADGIILGEALIDESMITGESRAISKKMN
ASVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQSQKSNLENMADKVAGYLFYAALIVGIFSLIFWTISSNFSFAL
LLAVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGKFVVRNVIDFTDDTDIL
QIMAALEGSSTHPIAQSIVNAAQPLKSLKVEAIENIPGVGIKGQVNQHFYQIVNYKYLREHQLSYDESKIAQYLELGLTV
SFLINDQQKVLGFIALGDTPKADAKDFINGLLAQGITPVMLTGDNKETAQKIATALNIPEFRAELKPEDKAEIVKEYQKK
AGVLFIGDGINDSPALATATIGFAIGAGTSVAINTADVVLVNSNPSDVLDMINISKRMLKKMKQNLWFGAGYNIIAIPVA
AGILYPFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDKK
>Mature_680_residues
MKNETHSDAHEKMMNEPHHDHEMMQMETDGHDMDMMNHGGHMMHMGDMSKKLKVSIVLMIPLLLISPIAGFTILKFPGSE
ILQLILGTIIFFYSGTPFFSGAKGELKSHKPAMMMLITMGITVAYAYSVYATIMSLNGQMGMNFWFELATLIVIMLIGHL
IEMKAIMGAGDALKDLASLVPKKAHLKNGEDVELSELKVGDLLLVKENEKIPADGIILGEALIDESMITGESRAISKKMN
ASVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQSQKSNLENMADKVAGYLFYAALIVGIFSLIFWTISSNFSFAL
LLAVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNRTSLEKINTIKYALMDKTGTLTDGKFVVRNVIDFTDDTDIL
QIMAALEGSSTHPIAQSIVNAAQPLKSLKVEAIENIPGVGIKGQVNQHFYQIVNYKYLREHQLSYDESKIAQYLELGLTV
SFLINDQQKVLGFIALGDTPKADAKDFINGLLAQGITPVMLTGDNKETAQKIATALNIPEFRAELKPEDKAEIVKEYQKK
AGVLFIGDGINDSPALATATIGFAIGAGTSVAINTADVVLVNSNPSDVLDMINISKRMLKKMKQNLWFGAGYNIIAIPVA
AGILYPFTGIYIDPLIAAVLMSISTVIVSINAMGLRYDKK

Specific function: Involved in copper transport [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily [H]

Homologues:

Organism=Homo sapiens, GI115529486, Length=728, Percent_Identity=29.9450549450549, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI55743071, Length=744, Percent_Identity=29.5698924731183, Blast_Score=275, Evalue=9e-74,
Organism=Homo sapiens, GI55743073, Length=515, Percent_Identity=32.2330097087379, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI48762691, Length=591, Percent_Identity=23.6886632825719, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI48762687, Length=591, Percent_Identity=23.6886632825719, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI48762689, Length=591, Percent_Identity=24.0270727580372, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI48762685, Length=591, Percent_Identity=24.0270727580372, Blast_Score=88, Evalue=3e-17,
Organism=Escherichia coli, GI1786691, Length=645, Percent_Identity=32.7131782945736, Blast_Score=304, Evalue=1e-83,
Organism=Escherichia coli, GI1789879, Length=565, Percent_Identity=30.9734513274336, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1786914, Length=462, Percent_Identity=28.1385281385281, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI2367363, Length=628, Percent_Identity=21.9745222929936, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17556548, Length=670, Percent_Identity=28.8059701492537, Blast_Score=239, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI71997262, Length=625, Percent_Identity=22.88, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71997275, Length=625, Percent_Identity=22.88, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71997269, Length=561, Percent_Identity=23.3511586452763, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17554158, Length=166, Percent_Identity=27.710843373494, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71988506, Length=166, Percent_Identity=27.710843373494, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193210130, Length=166, Percent_Identity=27.710843373494, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320475, Length=685, Percent_Identity=31.970802919708, Blast_Score=278, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6319772, Length=679, Percent_Identity=28.1296023564065, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6325221, Length=564, Percent_Identity=21.2765957446809, Blast_Score=104, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6321430, Length=563, Percent_Identity=23.0905861456483, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321432, Length=236, Percent_Identity=25.8474576271186, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221329854, Length=477, Percent_Identity=29.979035639413, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24762455, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762453, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762447, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762457, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762449, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762445, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24762451, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17136664, Length=201, Percent_Identity=29.3532338308458, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668696, Length=242, Percent_Identity=26.8595041322314, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281366617, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI161085803, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24668708, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24668704, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 74149; Mature: 74149

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00154 ATPASE_E1_E2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNETHSDAHEKMMNEPHHDHEMMQMETDGHDMDMMNHGGHMMHMGDMSKKLKVSIVLMI
CCCCCCCHHHHHHHCCCCCCCHHHEECCCCCCCHHHHCCCCEEEECCCCCHHHHHHHHHH
PLLLISPIAGFTILKFPGSEILQLILGTIIFFYSGTPFFSGAKGELKSHKPAMMMLITMG
HHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
ITVAYAYSVYATIMSLNGQMGMNFWFELATLIVIMLIGHLIEMKAIMGAGDALKDLASLV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
PKKAHLKNGEDVELSELKVGDLLLVKENEKIPADGIILGEALIDESMITGESRAISKKMN
CCHHHCCCCCCCCHHHCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHC
ASVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQSQKSNLENMADKVAGYLFYAAL
CEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGIFSLIFWTISSNFSFALLLAVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
TSLEKINTIKYALMDKTGTLTDGKFVVRNVIDFTDDTDILQIMAALEGSSTHPIAQSIVN
CHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHH
AAQPLKSLKVEAIENIPGVGIKGQVNQHFYQIVNYKYLREHQLSYDESKIAQYLELGLTV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
SFLINDQQKVLGFIALGDTPKADAKDFINGLLAQGITPVMLTGDNKETAQKIATALNIPE
EEEECCCHHHEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCHH
FRAELKPEDKAEIVKEYQKKAGVLFIGDGINDSPALATATIGFAIGAGTSVAINTADVVL
HHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECEEEEE
VNSNPSDVLDMINISKRMLKKMKQNLWFGAGYNIIAIPVAAGILYPFTGIYIDPLIAAVL
ECCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
MSISTVIVSINAMGLRYDKK
HHHHHHHHHHHHHCEEECCC
>Mature Secondary Structure
MKNETHSDAHEKMMNEPHHDHEMMQMETDGHDMDMMNHGGHMMHMGDMSKKLKVSIVLMI
CCCCCCCHHHHHHHCCCCCCCHHHEECCCCCCCHHHHCCCCEEEECCCCCHHHHHHHHHH
PLLLISPIAGFTILKFPGSEILQLILGTIIFFYSGTPFFSGAKGELKSHKPAMMMLITMG
HHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
ITVAYAYSVYATIMSLNGQMGMNFWFELATLIVIMLIGHLIEMKAIMGAGDALKDLASLV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
PKKAHLKNGEDVELSELKVGDLLLVKENEKIPADGIILGEALIDESMITGESRAISKKMN
CCHHHCCCCCCCCHHHCCCCCEEEEECCCCCCCCCEEEHHHHHHHHHHCCCHHHHHHHHC
ASVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQSQKSNLENMADKVAGYLFYAAL
CEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGIFSLIFWTISSNFSFALLLAVSVFVIACPHALGLAVPLVVSRLTSISAKNGLLIQNR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
TSLEKINTIKYALMDKTGTLTDGKFVVRNVIDFTDDTDILQIMAALEGSSTHPIAQSIVN
CHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHH
AAQPLKSLKVEAIENIPGVGIKGQVNQHFYQIVNYKYLREHQLSYDESKIAQYLELGLTV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
SFLINDQQKVLGFIALGDTPKADAKDFINGLLAQGITPVMLTGDNKETAQKIATALNIPE
EEEECCCHHHEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCHH
FRAELKPEDKAEIVKEYQKKAGVLFIGDGINDSPALATATIGFAIGAGTSVAINTADVVL
HHHCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECEEEEE
VNSNPSDVLDMINISKRMLKKMKQNLWFGAGYNIIAIPVAAGILYPFTGIYIDPLIAAVL
ECCCHHHHHHHHHHHHHHHHHHHHHCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
MSISTVIVSINAMGLRYDKK
HHHHHHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA