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The map label for this gene is ldhX [H]

Identifier: 125624240

GI number: 125624240

Start: 1396766

End: 1397737

Strand: Reverse

Name: ldhX [H]

Synonym: llmg_1429

Alternate gene names: 125624240

Gene position: 1397737-1396766 (Counterclockwise)

Preceding gene: 125624241

Following gene: 125624239

Centisome position: 55.26

GC content: 38.07

Gene sequence:

>972_bases
ATGAAAATTAATAATAAAAAAGTTGTAATTGTGGGAGCTGGAGCAGTAGGGAGTACTTATGCTCATAATTTGGTCGTTGA
TGATTTAGCAGATGAAATCGCCATTATCAATACTAATAAAAGTAAGGCTTCAGCCAATAGTTTGGACTTACTTCATGCTC
TGCCTTATTTAAACTCAGCTCCTAAAAATATTTATGCAGCAGACTACGCTGATGTTGCTGACGCCGATATCGTTGTTTTA
TCCGCTAATGCTCCGTCAGCTACCTTTGGTAAAAATCCAGACCGTCTTCAATTACTAGAAAATAATGTTGAGATGATTCG
TGATATCACGCGAAAAACAATGGACGCTGGCTTTGACGGTATTTTCTTAGTAGCTTCAAACCCCGTAGACGTACTTGCTC
AAGTAGTTGCTGAAGTTTCTGGCTTACCTAAACACCGGATTATTGGAACAGGAACCTTGCTTGAAACAAGTCGAATGCGA
CAAATTGTAGCTGAGAAACTTCAAATTAACCCTAAAAGTATTCATGGTTATGTTTTAGCTGAACATGGGAAATCTAGTTT
TGCCGCTTGGTCCAATGTTACTGTTGGGGCAATTCCATTAACAACTTGGCTTGAAAAATATCCAAATCCAGATTTTCCGA
CATTTGATGAAATTGATCAAGAAATTCGTGAAGTTGGTTTAGATATTTTCATGCAAAAAGGAAATACTTCATACGGAATC
GCAGCTTCATTAGCACGTTTAACAAGAGCAATTTTCCGAAATGAGAGCGTCATTTTACCTGTTTCGGCTCATTTGACAGG
TCAGTATGGACAAGCTGAACTATATACAGGTAGTCCAGCAATAATCGACCGGACAGGTGTTCGAGCCGTTTTAGAATTGG
AATTAACAGCAGAAGAGCAAGGTAAATTTGAACATTCTGCAGCACTCTTAAAAGAGAACTTTGAATCCATCAAGGAAAAA
TGCACATTATAA

Upstream 100 bases:

>100_bases
GAGATTTTAAAGCGTAAGAAACTAGGAAAAGAGATTTGGAAAGGGAGCCAAAAACGTTGTGAGTCAATAGTTAACTCACT
TGTTTTTTTGTGAAAAATAG

Downstream 100 bases:

>100_bases
AATAAGGGATAGATAATTATCCCTTTTTTTATTTAATTCAACGAAATAATATTTCTTAAATAAAAAAATAAAATTAATGC
TTGAAATAATAATTCATTTA

Product: L-lactate dehydrogenase

Products: NA

Alternate protein names: L-LDH 3 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKINNKKVVIVGAGAVGSTYAHNLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNSAPKNIYAADYADVADADIVVL
SANAPSATFGKNPDRLQLLENNVEMIRDITRKTMDAGFDGIFLVASNPVDVLAQVVAEVSGLPKHRIIGTGTLLETSRMR
QIVAEKLQINPKSIHGYVLAEHGKSSFAAWSNVTVGAIPLTTWLEKYPNPDFPTFDEIDQEIREVGLDIFMQKGNTSYGI
AASLARLTRAIFRNESVILPVSAHLTGQYGQAELYTGSPAIIDRTGVRAVLELELTAEEQGKFEHSAALLKENFESIKEK
CTL

Sequences:

>Translated_323_residues
MKINNKKVVIVGAGAVGSTYAHNLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNSAPKNIYAADYADVADADIVVL
SANAPSATFGKNPDRLQLLENNVEMIRDITRKTMDAGFDGIFLVASNPVDVLAQVVAEVSGLPKHRIIGTGTLLETSRMR
QIVAEKLQINPKSIHGYVLAEHGKSSFAAWSNVTVGAIPLTTWLEKYPNPDFPTFDEIDQEIREVGLDIFMQKGNTSYGI
AASLARLTRAIFRNESVILPVSAHLTGQYGQAELYTGSPAIIDRTGVRAVLELELTAEEQGKFEHSAALLKENFESIKEK
CTL
>Mature_323_residues
MKINNKKVVIVGAGAVGSTYAHNLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNSAPKNIYAADYADVADADIVVL
SANAPSATFGKNPDRLQLLENNVEMIRDITRKTMDAGFDGIFLVASNPVDVLAQVVAEVSGLPKHRIIGTGTLLETSRMR
QIVAEKLQINPKSIHGYVLAEHGKSSFAAWSNVTVGAIPLTTWLEKYPNPDFPTFDEIDQEIREVGLDIFMQKGNTSYGI
AASLARLTRAIFRNESVILPVSAHLTGQYGQAELYTGSPAIIDRTGVRAVLELELTAEEQGKFEHSAALLKENFESIKEK
CTL

Specific function: Unknown

COG id: COG0039

COG function: function code C; Malate/lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH/MDH superfamily. LDH family [H]

Homologues:

Organism=Homo sapiens, GI291575128, Length=322, Percent_Identity=33.8509316770186, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI4557032, Length=322, Percent_Identity=33.8509316770186, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI5031857, Length=311, Percent_Identity=32.475884244373, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI260099723, Length=311, Percent_Identity=32.475884244373, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI15082234, Length=317, Percent_Identity=32.1766561514196, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI9257228, Length=306, Percent_Identity=34.640522875817, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI4504973, Length=306, Percent_Identity=34.640522875817, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI47059044, Length=327, Percent_Identity=32.1100917431193, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI221136809, Length=327, Percent_Identity=32.1100917431193, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI260099727, Length=219, Percent_Identity=34.703196347032, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI260099725, Length=219, Percent_Identity=34.2465753424658, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI207028494, Length=220, Percent_Identity=32.7272727272727, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI103472011, Length=296, Percent_Identity=22.2972972972973, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI103472015, Length=186, Percent_Identity=23.6559139784946, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17535107, Length=297, Percent_Identity=31.6498316498317, Blast_Score=154, Evalue=5e-38,
Organism=Drosophila melanogaster, GI17136226, Length=313, Percent_Identity=30.0319488817891, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI45550422, Length=309, Percent_Identity=32.0388349514563, Blast_Score=168, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001557
- InterPro:   IPR011304
- InterPro:   IPR022383
- InterPro:   IPR001236
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02866 Ldh_1_C; PF00056 Ldh_1_N [H]

EC number: =1.1.1.27 [H]

Molecular weight: Translated: 35047; Mature: 35047

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINNKKVVIVGAGAVGSTYAHNLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNSA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCC
PKNIYAADYADVADADIVVLSANAPSATFGKNPDRLQLLENNVEMIRDITRKTMDAGFDG
CCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
IFLVASNPVDVLAQVVAEVSGLPKHRIIGTGTLLETSRMRQIVAEKLQINPKSIHGYVLA
EEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
EHGKSSFAAWSNVTVGAIPLTTWLEKYPNPDFPTFDEIDQEIREVGLDIFMQKGNTSYGI
ECCCCCHHECCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHEEEECCCCCHHH
AASLARLTRAIFRNESVILPVSAHLTGQYGQAELYTGSPAIIDRTGVRAVLELELTAEEQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCEEECCCCEEEEEEEEECHHC
GKFEHSAALLKENFESIKEKCTL
CCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKINNKKVVIVGAGAVGSTYAHNLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNSA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCC
PKNIYAADYADVADADIVVLSANAPSATFGKNPDRLQLLENNVEMIRDITRKTMDAGFDG
CCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
IFLVASNPVDVLAQVVAEVSGLPKHRIIGTGTLLETSRMRQIVAEKLQINPKSIHGYVLA
EEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
EHGKSSFAAWSNVTVGAIPLTTWLEKYPNPDFPTFDEIDQEIREVGLDIFMQKGNTSYGI
ECCCCCHHECCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHEEEECCCCCHHH
AASLARLTRAIFRNESVILPVSAHLTGQYGQAELYTGSPAIIDRTGVRAVLELELTAEEQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCEEECCCCEEEEEEEEECHHC
GKFEHSAALLKENFESIKEKCTL
CCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]