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The map label for this gene is matR

Identifier: 125624188

GI number: 125624188

Start: 1345518

End: 1347317

Strand: Reverse

Name: matR

Synonym: llmg_1371

Alternate gene names: 125624188

Gene position: 1347317-1345518 (Counterclockwise)

Preceding gene: 125624190

Following gene: 125624187

Centisome position: 53.26

GC content: 34.89

Gene sequence:

>1800_bases
ATGAAACCAACAATGGCAATTTTAGAAAGAATCAGTAAAAATTCACAAGAAAATATAGACGAAGTTTTTACAAGACTTTA
TCGTTATCTTTTACGTCCAGATATTTATTACGTGGCGTATCAAAATTTATATTCCAATAAAGGAGCTTCCACAAAAGGAA
TATTAGATGATACAGCGGATGGCTTTAGTGAAGAAAAAATAAAAAAGATTATTCAATCTTTAAAAGACGGAACTTACTAT
CCTCAACCTGTACGAAGAATGTATATTGCAAAAAAGAATTCTAAAAAGATGAGACCTTTAGGAATTCCAACTTTCACAGA
TAAATTGATCCAAGAAGCTGTGAGAATAATTCTTGAATCTATCTATGAACCGGTATTCGAAGATGTGTCTCACGGTTTTA
GACCTCAACGAAGCTGTCACACAGCTTTGAAAACAATCAAAAGAGAGTTTGGCGGCGCAAGATGGTTTGTGGAGGGAGAT
ATAAAAGGCTGCTTCGATAATATAGACCACGTTACACTCATTGGACTCATCAATCTTAAAATCAAAGATATGAAAATGAG
CCAATTGATTTATAAATTTCTAAAAGCAGGTTATCTGGAAAACTGGCAGTATCACAAAACTTACAGCGGAACACCTCAAG
GTGGAATTCTATCTCCTCTTTTGGCCAACATCTATCTTCATGAATTGGATAAGTTTGTTTTACAACTCAAAATGAAGTTT
GACCGAGAAAGTCCAGAAAGAATAACACCTGAATATCGGGAACTTCACAATGAGATAAAAAGAATTTCTCACCGTCTCAA
GAAGTTGGAGGGTGAAGAAAAAGCTAAAGTTCTTTTAGAATATCAAGAAAAACGTAAAAGATTACCCACACTCCCCTGTA
CCTCACAGACAAATAAAGTATTGAAATACGTCCGGTATGCGGACGACTTCATTATCTCTGTTAAAGGAAGCAAAGAGGAC
TGTCAATGGATAAAAGAACAATTAAAACTTTTTATTCATAACAAGCTAAAAATGGAATTGAGTGAAGAAAAAACACTCAT
CACACATAGCAGTCAACCCGCTCGTTTTCTGGGATATGATATACGAGTAAGGAGAAGTGGAACGATAAAACGATCTGGTA
AAGTCAAAAAGAGAACACTCAATGGGAGTGTAGAACTCCTTATTCCTCTTCAAGACAAAATTCGTCAATTTATTTTTGAC
AAGAAAATAGCTATCCAAAAGAAAGATAGCTCATGGTTTCCAGTTCACAGGAAATATCTTATTCGTTCAACAGACTTAGA
AATCATCACAATTTATAATTCTGAATTAAGAGGGATTTGTAATTACTACGGTCTAGCAAGTAATTTTAACCAGCTCAATT
ATTTTGCTTATCTTATGGAATACAGCTGTCTAAAAACGATAGCCTCCAAACATAAGGGAACACTTTCAAAAACCATTTCC
ATGTTTAAAGATGGAAGTGGTTCGTGGGGCATCCCGTATGAGATAAAGCAAGGTAAGCAGCGCCGTTATTTTGCAAATTT
TAGTGAATGTAAATCCCCTTATCAATTTACGGATGAGATAAGTCAAGCTCCTGTATTGTATGGCTATGCCCGGAATACTC
TTGAAAACAGGTTAAAAGCTAAATGTTGTGAATTATGTGGAACATCTGATGAAAATACTTCCTATGAAATTCACCATGTC
AATAAGGTCAAAAATCTTAAAGGCAAAGAAAAATGGGAAATGGCAATGATAGCGAAACAACGTAAAACTCTTGTTGTATG
CTTTCATTGTCATCGTCACGTGATTCATAAACACAAGTGA

Upstream 100 bases:

>100_bases
TACTCGTAGTAGTCTGAGAAGGGTAACGCCCTTTACATGGCAAAGGGGTACAGTTATTGTGTACTAAAATTAAAAATTGA
TTAGGGAGGAAAACCTCAAA

Downstream 100 bases:

>100_bases
ATTTTTACGAACGAACAATAACAGAGCCGTATACTCCGAGAGGGGTACGTACGGTTCCCGAAGAGGGTGGTGCAAACCAG
TCACAGTAATGTGAACAAGG

Product: maturase

Products: NA

Alternate protein names: Reverse-transcriptase; RNA maturase; DNA endonuclease

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTADGFSEEKIKKIIQSLKDGTYY
PQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILESIYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGD
IKGCFDNIDHVTLIGLINLKIKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF
DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLLEYQEKRKRLPTLPCTSQTNKVLKYVRYADDFIISVKGSKED
CQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPARFLGYDIRVRRSGTIKRSGKVKKRTLNGSVELLIPLQDKIRQFIFD
KKIAIQKKDSSWFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASKHKGTLSKTIS
MFKDGSGSWGIPYEIKQGKQRRYFANFSECKSPYQFTDEISQAPVLYGYARNTLENRLKAKCCELCGTSDENTSYEIHHV
NKVKNLKGKEKWEMAMIAKQRKTLVVCFHCHRHVIHKHK

Sequences:

>Translated_599_residues
MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTADGFSEEKIKKIIQSLKDGTYY
PQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILESIYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGD
IKGCFDNIDHVTLIGLINLKIKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF
DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLLEYQEKRKRLPTLPCTSQTNKVLKYVRYADDFIISVKGSKED
CQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPARFLGYDIRVRRSGTIKRSGKVKKRTLNGSVELLIPLQDKIRQFIFD
KKIAIQKKDSSWFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASKHKGTLSKTIS
MFKDGSGSWGIPYEIKQGKQRRYFANFSECKSPYQFTDEISQAPVLYGYARNTLENRLKAKCCELCGTSDENTSYEIHHV
NKVKNLKGKEKWEMAMIAKQRKTLVVCFHCHRHVIHKHK
>Mature_599_residues
MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTADGFSEEKIKKIIQSLKDGTYY
PQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILESIYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGD
IKGCFDNIDHVTLIGLINLKIKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF
DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLLEYQEKRKRLPTLPCTSQTNKVLKYVRYADDFIISVKGSKED
CQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPARFLGYDIRVRRSGTIKRSGKVKKRTLNGSVELLIPLQDKIRQFIFD
KKIAIQKKDSSWFPVHRKYLIRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASKHKGTLSKTIS
MFKDGSGSWGIPYEIKQGKQRRYFANFSECKSPYQFTDEISQAPVLYGYARNTLENRLKAKCCELCGTSDENTSYEIHHV
NKVKNLKGKEKWEMAMIAKQRKTLVVCFHCHRHVIHKHK

Specific function: Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities:reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site- specific cle

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain

Homologues:

Organism=Saccharomyces cerevisiae, GI6226520, Length=594, Percent_Identity=32.1548821548822, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6226521, Length=603, Percent_Identity=30.6799336650083, Blast_Score=236, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LTRA_LACLC (P0A3U0)

Other databases:

- EMBL:   U50902
- EMBL:   AF243383
- REBASE:   3057
- ProtClustDB:   CLSK862318
- BRENDA:   2.7.7.49
- InterPro:   IPR003615
- InterPro:   IPR002866
- InterPro:   IPR000477
- SMART:   SM00507

Pfam domain/function: PF01348 Intron_maturas2; PF00078 RVT_1

EC number: =2.7.7.49

Molecular weight: Translated: 70163; Mature: 70163

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTAD
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCCCCCCCCC
GFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILES
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLK
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCEEEEEEEEEE
IKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF
EEHHHHHHHHHHHHHCCHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLLEYQEKRKRLPTLPCTSQTNKV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPARFLGYD
HHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCHHHCCE
IRVRRSGTIKRSGKVKKRTLNGSVELLIPLQDKIRQFIFDKKIAIQKKDSSWFPVHRKYL
EEEECCCCCCCCCCCCEEECCCCEEEEEECHHHHHHHHHCCHHEEEECCCCCCCHHHHHH
IRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASKHKGTLSKTIS
EEECCEEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
MFKDGSGSWGIPYEIKQGKQRRYFANFSECKSPYQFTDEISQAPVLYGYARNTLENRLKA
HHHCCCCCCCCCHHHCCCCCHHHCCCHHHCCCCCHHHHHHHCCCEEEHHHHHHHHHHHHH
KCCELCGTSDENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCFHCHRHVIHKHK
HHHHHCCCCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCC
>Mature Secondary Structure
MKPTMAILERISKNSQENIDEVFTRLYRYLLRPDIYYVAYQNLYSNKGASTKGILDDTAD
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCCCCCCCCCC
GFSEEKIKKIIQSLKDGTYYPQPVRRMYIAKKNSKKMRPLGIPTFTDKLIQEAVRIILES
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IYEPVFEDVSHGFRPQRSCHTALKTIKREFGGARWFVEGDIKGCFDNIDHVTLIGLINLK
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCEEEEEEEEEE
IKDMKMSQLIYKFLKAGYLENWQYHKTYSGTPQGGILSPLLANIYLHELDKFVLQLKMKF
EEHHHHHHHHHHHHHCCHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
DRESPERITPEYRELHNEIKRISHRLKKLEGEEKAKVLLEYQEKRKRLPTLPCTSQTNKV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LKYVRYADDFIISVKGSKEDCQWIKEQLKLFIHNKLKMELSEEKTLITHSSQPARFLGYD
HHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCHHHCCE
IRVRRSGTIKRSGKVKKRTLNGSVELLIPLQDKIRQFIFDKKIAIQKKDSSWFPVHRKYL
EEEECCCCCCCCCCCCEEECCCCEEEEEECHHHHHHHHHCCHHEEEECCCCCCCHHHHHH
IRSTDLEIITIYNSELRGICNYYGLASNFNQLNYFAYLMEYSCLKTIASKHKGTLSKTIS
EEECCEEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
MFKDGSGSWGIPYEIKQGKQRRYFANFSECKSPYQFTDEISQAPVLYGYARNTLENRLKA
HHHCCCCCCCCCHHHCCCCCHHHCCCHHHCCCCCHHHHHHHCCCEEEHHHHHHHHHHHHH
KCCELCGTSDENTSYEIHHVNKVKNLKGKEKWEMAMIAKQRKTLVVCFHCHRHVIHKHK
HHHHHCCCCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655550; 11157264; 10488339; 9353259; 10413481; 11731786