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The map label for this gene is clpX [H]

Identifier: 125624160

GI number: 125624160

Start: 1315452

End: 1316687

Strand: Reverse

Name: clpX [H]

Synonym: llmg_1340

Alternate gene names: 125624160

Gene position: 1316687-1315452 (Counterclockwise)

Preceding gene: 125624161

Following gene: 125624159

Centisome position: 52.05

GC content: 34.87

Gene sequence:

>1236_bases
ATGTCAAATACACAAAATCCAAATATTCAATGCTCTTTCTGCGGAAAGAGTCAAGATGATGTAAAAAAGATGATTGCCGG
TTCAGATGTTTATATCTGTAACGAATGTATCGAACTTTCAACTCGTATCTTGGAAGAAGAATTAAAAGAAGAACAAGATT
CAGAGATGCTTGAAGTTAAGACGCCAAAAGAAATGTTTGACCATTTGAATGAATACGTTATTGGTCAAGAAAAGGCCAAA
CGTGCGCTTGCAGTTGCGGTTTATAATCATTATAAAAGAATTAATTTTACAGCAAGTAAAATTGCTGAAGATATTGAGCT
TCAAAAATCAAATATCTTACTCATTGGCCCAACAGGTTCAGGAAAGACTTTCCTTGCACAGACTTTAGCAAAATCACTCA
ATGTTCCTTTTGCCATTGCTGATGCGACAAGTTTGACTGAAGCAGGTTATGTGGGAGAAGATGTTGAAAATATTCTCTTA
AAACTTTTGCAAGCCAGTGACTTTAATATCGAACGTGCCGAACGTGGAATTATTTACATTGATGAAATCGATAAGATTGC
TAAAAAATCTGAAAATGTTTCAATCACTCGTGATGTTTCGGGTGAAGGAGTTCAACAAGCCCTTCTAAAAATTATTGAAG
GAACAGTTGCCAGTGTTCCACCACAAGGTGGACGTAAACACCCTAATCAAGAAATGATTCAAATAGACACCAAAAATATT
TTGTTTATTGTTGGTGGAGCTTTTGATGGAATTGAAGAAATTGTCAAACAACGTTTGGGTGAAAAAATCATTGGTTTTGG
TGCCAATAATAAAAAATTGAGCGATGAAGATTCTTATATGCAAGAAATTATCGCTGAGGATATTCAAAAGTTTGGGTTGA
TTCCTGAATTTATTGGACGTCTTCCGATTGTAGCTGCCTTAGAACGCTTAACTGAAGAAGACTTAATTCAAATTTTGACA
GAGCCTAAAAATGCTTTGATTAAACAATATAAACAACTTTTGTTATTTGATAATGTTGAACTTGAATTTAAAGATGGAGC
TCTTATGGCAATTGCGAAAAAAGCAATTGAGCGTAAAACAGGTGCGCGTGGGCTTCGTTCAATTATTGAAGAAGTGATGA
TGGATATTATGTTTGAAGTTCCAAGTCATGAAGAAATTACAAAAGTTATCATTACTGAAGCAGTTGTTGACGGAAAAGCT
GAGCCAGAAATGATTCGAGAGGCCGATAAAAAATGA

Upstream 100 bases:

>100_bases
TTCTGGAACTTTGTTTTAAAAGTATTTAGAAAAAGTATGTTATATAAGTAAGCTAACGACTATCAGTTTTATAGGTTAGC
ACAATCAGGAAAAAATAACT

Downstream 100 bases:

>100_bases
CCATTAATACAAATAATCTGACAATAACAATTTCAGCAGCATCAAAAAAACAATATCCTGAAAACGATTGGCCAGAAATT
GCCTTAGCAGGTCGTTCAAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSNTQNPNIQCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELKEEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFTASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLSDEDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFKDGALMAIAKKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIITEAVVDGKA
EPEMIREADKK

Sequences:

>Translated_411_residues
MSNTQNPNIQCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELKEEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFTASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLSDEDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFKDGALMAIAKKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIITEAVVDGKA
EPEMIREADKK
>Mature_410_residues
SNTQNPNIQCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELKEEQDSEMLEVKTPKEMFDHLNEYVIGQEKAKR
ALAVAVYNHYKRINFTASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
LLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNIL
FIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLSDEDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILTE
PKNALIKQYKQLLLFDNVELEFKDGALMAIAKKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIITEAVVDGKAE
PEMIREADKK

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=332, Percent_Identity=48.7951807228916, Blast_Score=322, Evalue=6e-88,
Organism=Escherichia coli, GI1786642, Length=402, Percent_Identity=61.1940298507463, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1790366, Length=211, Percent_Identity=35.0710900473934, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71982905, Length=320, Percent_Identity=44.375, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI71982908, Length=319, Percent_Identity=44.5141065830721, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI71988663, Length=389, Percent_Identity=40.1028277634961, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=252, Percent_Identity=42.0634920634921, Blast_Score=185, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6319704, Length=438, Percent_Identity=38.8127853881278, Blast_Score=267, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24648291, Length=325, Percent_Identity=46.7692307692308, Blast_Score=311, Evalue=4e-85,
Organism=Drosophila melanogaster, GI24648289, Length=325, Percent_Identity=46.7692307692308, Blast_Score=311, Evalue=4e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45849; Mature: 45718

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTQNPNIQCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELKEEQDSEMLEVK
CCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
TPKEMFDHLNEYVIGQEKAKRALAVAVYNHYKRINFTASKIAEDIELQKSNILLIGPTGS
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCC
GKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLLQASDFNIERAERGIIYI
CHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEEE
DEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCEEEEECCCE
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLSDEDSYMQEIIAEDIQKFGLIPEFIGR
EEEECCCHHHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCC
LPIVAALERLTEEDLIQILTEPKNALIKQYKQLLLFDNVELEFKDGALMAIAKKAIERKT
CHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHH
GARGLRSIIEEVMMDIMFEVPSHEEITKVIITEAVVDGKAEPEMIREADKK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SNTQNPNIQCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELKEEQDSEMLEVK
CCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
TPKEMFDHLNEYVIGQEKAKRALAVAVYNHYKRINFTASKIAEDIELQKSNILLIGPTGS
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCC
GKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLLQASDFNIERAERGIIYI
CHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEEE
DEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCEEEEECCCE
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLSDEDSYMQEIIAEDIQKFGLIPEFIGR
EEEECCCHHHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCC
LPIVAALERLTEEDLIQILTEPKNALIKQYKQLLLFDNVELEFKDGALMAIAKKAIERKT
CHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHH
GARGLRSIIEEVMMDIMFEVPSHEEITKVIITEAVVDGKAEPEMIREADKK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]