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The map label for this gene is murB [H]

Identifier: 125624149

GI number: 125624149

Start: 1305539

End: 1306438

Strand: Reverse

Name: murB [H]

Synonym: llmg_1329

Alternate gene names: 125624149

Gene position: 1306438-1305539 (Counterclockwise)

Preceding gene: 125624150

Following gene: 125624148

Centisome position: 51.65

GC content: 38.33

Gene sequence:

>900_bases
ATGATAAAAGAAACTGATCTTGAAAATATCCCAGATTTACTGATTAAATTTAATGAACCCCTATCAAATTATACTTACAC
AAAAGTAGGAGGACCAGCTGATATTCTGGCTTTTCCGGCTACAATAGAAGCATTGACAGAACTGTCAGCAAAAGCGAAAG
CAACTGATACACCGGTTACAGTTCTTGGAAATGCCTCAAATTTGATTGTTCGTGATGGTGGAATTCGTGGACTCGTTATT
TTACTTGAAAAACTTGATTCAGTAAAAGTGGCTGGTTATACCATTGAAGCGCAAGCAGGAGCGAAATTAAAAGAAGTCAC
TCAAGTGGCCCAAGCCAATTCACTGACAGGTTTTGAATTTGCTTGTGGGATTCCTGGCTCAATTGGTGGAGCGGTATTCA
TGAATGCTGGAGCTTATGGTGGTGAAATTTCCCAAGTTTTGGTAAGCTGTAAAGTGATGGATGCTGAGGGTAATGTTTCG
GTTTTAAGTGCAAGTGAAATGCAATTTGGTTATCGTCATTCCGTGATTCGTGATAAAAACTTAATTGTTCTGTCAGCAAA
ATTTGAACTCCAAGCAGGAGATCCAACACAAATTCAAAATGAAATGGATCGTCTTAATTTCTTACGTGAAAGTAAGCAAC
CTTTAGAATATCCAAGCTGTGGCTCAGTTTTTAAACGTCCAGTTGGTCACTTTGCAGGACAATTAATTCAAGAAGCTAAA
CTTCAAGGTCAGCGTATTGGCGGTGTCGAAGTCAGTAAAAAACATGCCGGTTTTATGGTTAATGTTGCTGATGGAAATGC
GACGGATTATGAAAAACTGATTGCTCTGGTCATTGAAAAAGTTAAAGAAAATTCAGGTGTGACATTAGAGCCTGAGGTCA
GAATTATTGGTGAAAAATAA

Upstream 100 bases:

>100_bases
CATCTTTGATAAAGCTAAAAATCTTGTGAATAAAAAGAAAGTTAAAGCCGAAATTTAAGACAAAATTGTCATCTTTAATA
GAAAATGATAAAATAAGGTT

Downstream 100 bases:

>100_bases
GACAGAATTTCCTGTCTTTTTCAAATTTCAACTTGATAAATCATCGAATTTAAGCTATAATTAATGATGTTCTGTGCATA
TACAGAAGATTTGACCGCTC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MIKETDLENIPDLLIKFNEPLSNYTYTKVGGPADILAFPATIEALTELSAKAKATDTPVTVLGNASNLIVRDGGIRGLVI
LLEKLDSVKVAGYTIEAQAGAKLKEVTQVAQANSLTGFEFACGIPGSIGGAVFMNAGAYGGEISQVLVSCKVMDAEGNVS
VLSASEMQFGYRHSVIRDKNLIVLSAKFELQAGDPTQIQNEMDRLNFLRESKQPLEYPSCGSVFKRPVGHFAGQLIQEAK
LQGQRIGGVEVSKKHAGFMVNVADGNATDYEKLIALVIEKVKENSGVTLEPEVRIIGEK

Sequences:

>Translated_299_residues
MIKETDLENIPDLLIKFNEPLSNYTYTKVGGPADILAFPATIEALTELSAKAKATDTPVTVLGNASNLIVRDGGIRGLVI
LLEKLDSVKVAGYTIEAQAGAKLKEVTQVAQANSLTGFEFACGIPGSIGGAVFMNAGAYGGEISQVLVSCKVMDAEGNVS
VLSASEMQFGYRHSVIRDKNLIVLSAKFELQAGDPTQIQNEMDRLNFLRESKQPLEYPSCGSVFKRPVGHFAGQLIQEAK
LQGQRIGGVEVSKKHAGFMVNVADGNATDYEKLIALVIEKVKENSGVTLEPEVRIIGEK
>Mature_299_residues
MIKETDLENIPDLLIKFNEPLSNYTYTKVGGPADILAFPATIEALTELSAKAKATDTPVTVLGNASNLIVRDGGIRGLVI
LLEKLDSVKVAGYTIEAQAGAKLKEVTQVAQANSLTGFEFACGIPGSIGGAVFMNAGAYGGEISQVLVSCKVMDAEGNVS
VLSASEMQFGYRHSVIRDKNLIVLSAKFELQAGDPTQIQNEMDRLNFLRESKQPLEYPSCGSVFKRPVGHFAGQLIQEAK
LQGQRIGGVEVSKKHAGFMVNVADGNATDYEKLIALVIEKVKENSGVTLEPEVRIIGEK

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=300, Percent_Identity=28.3333333333333, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32045; Mature: 32045

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKETDLENIPDLLIKFNEPLSNYTYTKVGGPADILAFPATIEALTELSAKAKATDTPVT
CCCCCCCHHHHHHHEEECCCCCCCEEEECCCCHHEEECHHHHHHHHHHHHHCCCCCCCEE
VLGNASNLIVRDGGIRGLVILLEKLDSVKVAGYTIEAQAGAKLKEVTQVAQANSLTGFEF
EEECCCEEEEECCCCCCHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCEE
ACGIPGSIGGAVFMNAGAYGGEISQVLVSCKVMDAEGNVSVLSASEMQFGYRHSVIRDKN
ECCCCCCCCCEEEEECCCCCHHHHHHHHEEEEECCCCCEEEEEHHHHCCCHHHHHCCCCC
LIVLSAKFELQAGDPTQIQNEMDRLNFLRESKQPLEYPSCGSVFKRPVGHFAGQLIQEAK
EEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQGQRIGGVEVSKKHAGFMVNVADGNATDYEKLIALVIEKVKENSGVTLEPEVRIIGEK
HCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCCEEEECCC
>Mature Secondary Structure
MIKETDLENIPDLLIKFNEPLSNYTYTKVGGPADILAFPATIEALTELSAKAKATDTPVT
CCCCCCCHHHHHHHEEECCCCCCCEEEECCCCHHEEECHHHHHHHHHHHHHCCCCCCCEE
VLGNASNLIVRDGGIRGLVILLEKLDSVKVAGYTIEAQAGAKLKEVTQVAQANSLTGFEF
EEECCCEEEEECCCCCCHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCEE
ACGIPGSIGGAVFMNAGAYGGEISQVLVSCKVMDAEGNVSVLSASEMQFGYRHSVIRDKN
ECCCCCCCCCEEEEECCCCCHHHHHHHHEEEEECCCCCEEEEEHHHHCCCHHHHHCCCCC
LIVLSAKFELQAGDPTQIQNEMDRLNFLRESKQPLEYPSCGSVFKRPVGHFAGQLIQEAK
EEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQGQRIGGVEVSKKHAGFMVNVADGNATDYEKLIALVIEKVKENSGVTLEPEVRIIGEK
HCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]