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The map label for this gene is yljE [H]

Identifier: 125624135

GI number: 125624135

Start: 1286555

End: 1287925

Strand: Reverse

Name: yljE [H]

Synonym: llmg_1315

Alternate gene names: 125624135

Gene position: 1287925-1286555 (Counterclockwise)

Preceding gene: 125624136

Following gene: 125624134

Centisome position: 50.92

GC content: 34.28

Gene sequence:

>1371_bases
ATGGACATGACAAATTTCAAGAAAAACGATATATTTGAAGCAGAAGTCCTTGATTTGACACATGAAGGGCAAGGAGTGGT
TAAAGTTGATTCTTACCCATTTTTTGTAGACAATGCCTTACCTGGTGAACGGATAAAAATGCGCGTTCTTAAAGTTGGAA
AATCATTTGGTTTTGGGCGTGTGGATGAATTTATAAGCCAAAGTGAGCATCGCACGACTCAGTTAAATCTTGATTATTTA
AGAACTGGGATTGCTGACTTTGGTCATCTGACTTATAATGAACAAGTAAAATTTAAACAAAAGCAAGTCGTTGATATTTT
AAGAAAAACGGCTGGGAAGGAAGATTTCCCTGTTTCTCCAGTTATTGAATCTATTAAAACGATAAAATATCGAAATAAGG
CACAGATTCCTGTTCAAATGGTTAATGGGATTTTAACTACTGGATTTTATAGAAAAAATTCTCACTCATTAATTCCAGTC
GAAGATTTTTATATTCAACATCCTGAAATTGATGCAGTTGTCCTTTTTTTGCGTGATGAGTTTCGGAAAATTAATTTACA
AGCTTACGATGAAAAAACGCGCAAAGGTTGGCTACGAAATATTGTGGTTAGAAGAGGTTTTCATACAAGTGAAATGATGG
TTAGCCTTGTTGTAACCAGTAAAAAACTTCCAGAAAATGTTGATTTGGTAATTGACAAATTAGTGGAGCATTTTACTAAT
ATTAAATCTGTTCAACTCAATATTAATAATGGAACTGGCTCATTTATTTTAGGTAAAGAGTTCGTTTTATTGTATGGAAA
AGATTTTATTACAGATTTGATGTTGGACAAAACTTATCAAATTTCTGCACCAGCTTTTTATCAAGTCAACACTCCACAAG
CTGAAAAACTTTATGAAACAGCCTTTGAATTCGCAGAATTAAAACCAGGAGATATTGTTATCGATGCTTATTCTGGTATT
GGAACAATCGGAATCAGCATGGCCGATCGAGTCGCTGAGGTTTATGGGATGGAAGTTGTTCCGGCTGCTGTTGAAAATGC
AAAACGTAATGCTCAATTAAATGAACTTGAGAACACACATTATGAAGTAGGAACAGCAGAAAAAATTATGCCCAAGTGGC
TTGATGAAGGAATAAAACCTGATGTTATTTTTGTTGACCCACCAAGAAAAGGGCTCGATGAAACTTTTATTAAATCAGCA
ACAGCAACTAATCCTCGGAGAATCGTTTATATTTCATGTAATCCTGCAACCTTTGCTCGAGATGTTGTACGTTTTGAAAA
CGAAGGCTATATTTTAGATAAAGTTCAACCAGTTGATTTATTCCCACAAACGCATCATATTGAACTTGTTGCTCGTTTTA
ATAAAAAATAA

Upstream 100 bases:

>100_bases
CGATTATCAGAGCAGTTATGGATAAGACAGTTGAGTAACTTCTTTATTATTCAGCTTTTAGTGATGTTTGTTGAACCTTA
TTGAAATACTATGTTATAAT

Downstream 100 bases:

>100_bases
AAGAGGATAGTATTTTAGAAAATCCTAACCATAGAAAGAAAATCATGATTCGCATAACACAAATCAAAATTTCAATTGAC
GAACCTGTCAGTAAAGTTAA

Product: putative RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MDMTNFKKNDIFEAEVLDLTHEGQGVVKVDSYPFFVDNALPGERIKMRVLKVGKSFGFGRVDEFISQSEHRTTQLNLDYL
RTGIADFGHLTYNEQVKFKQKQVVDILRKTAGKEDFPVSPVIESIKTIKYRNKAQIPVQMVNGILTTGFYRKNSHSLIPV
EDFYIQHPEIDAVVLFLRDEFRKINLQAYDEKTRKGWLRNIVVRRGFHTSEMMVSLVVTSKKLPENVDLVIDKLVEHFTN
IKSVQLNINNGTGSFILGKEFVLLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEKLYETAFEFAELKPGDIVIDAYSGI
GTIGISMADRVAEVYGMEVVPAAVENAKRNAQLNELENTHYEVGTAEKIMPKWLDEGIKPDVIFVDPPRKGLDETFIKSA
TATNPRRIVYISCNPATFARDVVRFENEGYILDKVQPVDLFPQTHHIELVARFNKK

Sequences:

>Translated_456_residues
MDMTNFKKNDIFEAEVLDLTHEGQGVVKVDSYPFFVDNALPGERIKMRVLKVGKSFGFGRVDEFISQSEHRTTQLNLDYL
RTGIADFGHLTYNEQVKFKQKQVVDILRKTAGKEDFPVSPVIESIKTIKYRNKAQIPVQMVNGILTTGFYRKNSHSLIPV
EDFYIQHPEIDAVVLFLRDEFRKINLQAYDEKTRKGWLRNIVVRRGFHTSEMMVSLVVTSKKLPENVDLVIDKLVEHFTN
IKSVQLNINNGTGSFILGKEFVLLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEKLYETAFEFAELKPGDIVIDAYSGI
GTIGISMADRVAEVYGMEVVPAAVENAKRNAQLNELENTHYEVGTAEKIMPKWLDEGIKPDVIFVDPPRKGLDETFIKSA
TATNPRRIVYISCNPATFARDVVRFENEGYILDKVQPVDLFPQTHHIELVARFNKK
>Mature_456_residues
MDMTNFKKNDIFEAEVLDLTHEGQGVVKVDSYPFFVDNALPGERIKMRVLKVGKSFGFGRVDEFISQSEHRTTQLNLDYL
RTGIADFGHLTYNEQVKFKQKQVVDILRKTAGKEDFPVSPVIESIKTIKYRNKAQIPVQMVNGILTTGFYRKNSHSLIPV
EDFYIQHPEIDAVVLFLRDEFRKINLQAYDEKTRKGWLRNIVVRRGFHTSEMMVSLVVTSKKLPENVDLVIDKLVEHFTN
IKSVQLNINNGTGSFILGKEFVLLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEKLYETAFEFAELKPGDIVIDAYSGI
GTIGISMADRVAEVYGMEVVPAAVENAKRNAQLNELENTHYEVGTAEKIMPKWLDEGIKPDVIFVDPPRKGLDETFIKSA
TATNPRRIVYISCNPATFARDVVRFENEGYILDKVQPVDLFPQTHHIELVARFNKK

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=417, Percent_Identity=30.2158273381295, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI51173878, Length=417, Percent_Identity=30.2158273381295, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI269784680, Length=420, Percent_Identity=27.3809523809524, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI269784676, Length=420, Percent_Identity=27.3809523809524, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI20149688, Length=420, Percent_Identity=27.3809523809524, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI269784678, Length=211, Percent_Identity=34.5971563981043, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1789148, Length=172, Percent_Identity=36.046511627907, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787083, Length=353, Percent_Identity=23.7960339943343, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790403, Length=177, Percent_Identity=27.683615819209, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997438, Length=169, Percent_Identity=30.1775147928994, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322909, Length=152, Percent_Identity=32.2368421052632, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666579, Length=473, Percent_Identity=26.6384778012685, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 52031; Mature: 52031

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMTNFKKNDIFEAEVLDLTHEGQGVVKVDSYPFFVDNALPGERIKMRVLKVGKSFGFGR
CCCCCCCCCCCCEEHEEEEEECCCCEEEECCCCEEECCCCCCHHHHHHHHHHCCCCCCCH
VDEFISQSEHRTTQLNLDYLRTGIADFGHLTYNEQVKFKQKQVVDILRKTAGKEDFPVSP
HHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
VIESIKTIKYRNKAQIPVQMVNGILTTGFYRKNSHSLIPVEDFYIQHPEIDAVVLFLRDE
HHHHHHHHHCCCCCCCHHHHHHHHHHCCEEECCCCCCCCHHHHEEECCCCCEEEEEEECC
FRKINLQAYDEKTRKGWLRNIVVRRGFHTSEMMVSLVVTSKKLPENVDLVIDKLVEHFTN
CCEECEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
IKSVQLNINNGTGSFILGKEFVLLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEKLYET
CEEEEEEEECCCCCEEECCCEEEEECHHHHHHHHHCCCEEECCCEEEEECCCHHHHHHHH
AFEFAELKPGDIVIDAYSGIGTIGISMADRVAEVYGMEVVPAAVENAKRNAQLNELENTH
HHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCC
YEVGTAEKIMPKWLDEGIKPDVIFVDPPRKGLDETFIKSATATNPRRIVYISCNPATFAR
EECCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCHHHHH
DVVRFENEGYILDKVQPVDLFPQTHHIELVARFNKK
HHHHCCCCCEEEECCCCCCCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MDMTNFKKNDIFEAEVLDLTHEGQGVVKVDSYPFFVDNALPGERIKMRVLKVGKSFGFGR
CCCCCCCCCCCCEEHEEEEEECCCCEEEECCCCEEECCCCCCHHHHHHHHHHCCCCCCCH
VDEFISQSEHRTTQLNLDYLRTGIADFGHLTYNEQVKFKQKQVVDILRKTAGKEDFPVSP
HHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
VIESIKTIKYRNKAQIPVQMVNGILTTGFYRKNSHSLIPVEDFYIQHPEIDAVVLFLRDE
HHHHHHHHHCCCCCCCHHHHHHHHHHCCEEECCCCCCCCHHHHEEECCCCCEEEEEEECC
FRKINLQAYDEKTRKGWLRNIVVRRGFHTSEMMVSLVVTSKKLPENVDLVIDKLVEHFTN
CCEECEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
IKSVQLNINNGTGSFILGKEFVLLYGKDFITDLMLDKTYQISAPAFYQVNTPQAEKLYET
CEEEEEEEECCCCCEEECCCEEEEECHHHHHHHHHCCCEEECCCEEEEECCCHHHHHHHH
AFEFAELKPGDIVIDAYSGIGTIGISMADRVAEVYGMEVVPAAVENAKRNAQLNELENTH
HHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCC
YEVGTAEKIMPKWLDEGIKPDVIFVDPPRKGLDETFIKSATATNPRRIVYISCNPATFAR
EECCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCHHHHH
DVVRFENEGYILDKVQPVDLFPQTHHIELVARFNKK
HHHHCCCCCEEEECCCCCCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]