| Definition | Lactococcus lactis subsp. cremoris MG1363, complete genome. |
|---|---|
| Accession | NC_009004 |
| Length | 2,529,478 |
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The map label for this gene is yqhE [C]
Identifier: 125624078
GI number: 125624078
Start: 1224964
End: 1225821
Strand: Direct
Name: yqhE [C]
Synonym: llmg_1253
Alternate gene names: 125624078
Gene position: 1224964-1225821 (Clockwise)
Preceding gene: 125624076
Following gene: 125624079
Centisome position: 48.43
GC content: 32.98
Gene sequence:
>858_bases ATGAAAACATTTAAATTAAACAATGGGGTAGAAATTCCTGTATTGGGTTTTGGAGTCTTCCAAATTCCACAGGAACAAAC GAAACAAGCTGTATTAGATGCAATTGAGGTAGGTTATAGACACTTTGATACAGCTCAATCTTATTTTAATGAAGAAGAAG TTGGTGATGCTATTGCCGAAACCATTATTCCTCGAGAAAACTTATTTATCACCACTAAAGTATGGCTCAGTAACTATGGA TATGAGAATACGAAAACTTCTATTAAAATATCACTAGAAAAAATGAAACTTGATTATCTTGATTTAGTATTACTTCATCA ACCTTTTGGGGATGTATTTGGGAGCTATAAAGCACTTGTAGATTTGCAAAAAGAAGGTAAAATACGAGCTATTGGTGTAT CTAATTTTAATGAACTACGTTTAGCAGATATTATTTCTTTTCAAGATACTGTACCACAGATAAATCAAATTGAAATCAAT CCGTTTCATCAAAGAGAGGAGGATTTGCAAAACGCTTTATCACGTGGGAATGTACAATTAGAGGCATGGGCACCATTTGC AGAGGGGAAAAATGGTATTTTTGAAAATGAAATTTTATCAGTTATTGGCAAAAAATACGGCAAAAGTCCAGCACAAGTCA TTTTACGTTGGTTATATGAACGAGGGATTGTCAGTCTTGCTAAATCAGTAAAGAAAGATCGCATGAAACAAAATATTGAT ATCTTTAATTTCAGCTTAACATCAGAAGATAAGGAACAAATTGGTACTTTACAAACATCTGGTAGCCAGTTCTTTGATCA TGATGATCCCAAGACTGTAGACTTTTTCGAAAAACTTGTTAAAGAACGAGAAATTTGA
Upstream 100 bases:
>100_bases GAAATGATTTGGGAAGGAGCAGCTACTAATGAAAGAGAATTGCATCTATTAAAAGTCAAATTTGAAAAAAATAACAGAAT TTAAGAAAGTGAGATAAAAA
Downstream 100 bases:
>100_bases TATATAAATCAATATAAAAATATATTTTTTACACTCATCGAACTTATTGGAAGCATTGTCTCCAATATTATTGCAGTAGT TAGTCTTGTAGTTGTACTCA
Product: hypothetical protein
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 285; Mature: 285
Protein sequence:
>285_residues MKTFKLNNGVEIPVLGFGVFQIPQEQTKQAVLDAIEVGYRHFDTAQSYFNEEEVGDAIAETIIPRENLFITTKVWLSNYG YENTKTSIKISLEKMKLDYLDLVLLHQPFGDVFGSYKALVDLQKEGKIRAIGVSNFNELRLADIISFQDTVPQINQIEIN PFHQREEDLQNALSRGNVQLEAWAPFAEGKNGIFENEILSVIGKKYGKSPAQVILRWLYERGIVSLAKSVKKDRMKQNID IFNFSLTSEDKEQIGTLQTSGSQFFDHDDPKTVDFFEKLVKEREI
Sequences:
>Translated_285_residues MKTFKLNNGVEIPVLGFGVFQIPQEQTKQAVLDAIEVGYRHFDTAQSYFNEEEVGDAIAETIIPRENLFITTKVWLSNYG YENTKTSIKISLEKMKLDYLDLVLLHQPFGDVFGSYKALVDLQKEGKIRAIGVSNFNELRLADIISFQDTVPQINQIEIN PFHQREEDLQNALSRGNVQLEAWAPFAEGKNGIFENEILSVIGKKYGKSPAQVILRWLYERGIVSLAKSVKKDRMKQNID IFNFSLTSEDKEQIGTLQTSGSQFFDHDDPKTVDFFEKLVKEREI >Mature_285_residues MKTFKLNNGVEIPVLGFGVFQIPQEQTKQAVLDAIEVGYRHFDTAQSYFNEEEVGDAIAETIIPRENLFITTKVWLSNYG YENTKTSIKISLEKMKLDYLDLVLLHQPFGDVFGSYKALVDLQKEGKIRAIGVSNFNELRLADIISFQDTVPQINQIEIN PFHQREEDLQNALSRGNVQLEAWAPFAEGKNGIFENEILSVIGKKYGKSPAQVILRWLYERGIVSLAKSVKKDRMKQNID IFNFSLTSEDKEQIGTLQTSGSQFFDHDDPKTVDFFEKLVKEREI
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=286, Percent_Identity=31.1188811188811, Blast_Score=177, Evalue=1e-44, Organism=Homo sapiens, GI5174391, Length=286, Percent_Identity=31.1188811188811, Blast_Score=177, Evalue=1e-44, Organism=Homo sapiens, GI310109922, Length=276, Percent_Identity=35.5072463768116, Blast_Score=161, Evalue=8e-40, Organism=Homo sapiens, GI24497583, Length=306, Percent_Identity=31.3725490196078, Blast_Score=158, Evalue=5e-39, Organism=Homo sapiens, GI5453543, Length=296, Percent_Identity=32.4324324324324, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI310109920, Length=297, Percent_Identity=32.6599326599327, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI45446745, Length=297, Percent_Identity=32.6599326599327, Blast_Score=155, Evalue=3e-38, Organism=Homo sapiens, GI4503285, Length=297, Percent_Identity=32.6599326599327, Blast_Score=155, Evalue=3e-38, Organism=Homo sapiens, GI93277124, Length=295, Percent_Identity=30.5084745762712, Blast_Score=148, Evalue=5e-36, Organism=Homo sapiens, GI24497585, Length=292, Percent_Identity=31.1643835616438, Blast_Score=147, Evalue=1e-35, Organism=Homo sapiens, GI5174695, Length=292, Percent_Identity=30.1369863013699, Blast_Score=145, Evalue=4e-35, Organism=Homo sapiens, GI223468663, Length=290, Percent_Identity=30.6896551724138, Blast_Score=144, Evalue=8e-35, Organism=Homo sapiens, GI4502049, Length=280, Percent_Identity=34.2857142857143, Blast_Score=144, Evalue=1e-34, Organism=Homo sapiens, GI300116273, Length=280, Percent_Identity=28.5714285714286, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI300116271, Length=269, Percent_Identity=28.996282527881, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI291291012, Length=274, Percent_Identity=29.1970802919708, Blast_Score=122, Evalue=4e-28, Organism=Homo sapiens, GI310109926, Length=114, Percent_Identity=40.3508771929825, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI207028673, Length=114, Percent_Identity=40.3508771929825, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI310109924, Length=145, Percent_Identity=33.7931034482759, Blast_Score=78, Evalue=1e-14, Organism=Escherichia coli, GI87082198, Length=259, Percent_Identity=39.7683397683398, Blast_Score=199, Evalue=2e-52, Organism=Escherichia coli, GI1786400, Length=256, Percent_Identity=35.15625, Blast_Score=155, Evalue=2e-39, Organism=Escherichia coli, GI1788081, Length=268, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1787674, Length=257, Percent_Identity=24.5136186770428, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI87081735, Length=293, Percent_Identity=23.5494880546075, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17537079, Length=294, Percent_Identity=32.6530612244898, Blast_Score=160, Evalue=8e-40, Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=32.4909747292419, Blast_Score=158, Evalue=4e-39, Organism=Caenorhabditis elegans, GI17537077, Length=288, Percent_Identity=30.9027777777778, Blast_Score=157, Evalue=8e-39, Organism=Caenorhabditis elegans, GI17537075, Length=288, Percent_Identity=30.5555555555556, Blast_Score=153, Evalue=1e-37, Organism=Caenorhabditis elegans, GI17566692, Length=281, Percent_Identity=32.7402135231317, Blast_Score=150, Evalue=6e-37, Organism=Caenorhabditis elegans, GI17550248, Length=284, Percent_Identity=31.3380281690141, Blast_Score=143, Evalue=1e-34, Organism=Caenorhabditis elegans, GI17564128, Length=316, Percent_Identity=28.7974683544304, Blast_Score=142, Evalue=2e-34, Organism=Caenorhabditis elegans, GI17538386, Length=273, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17561298, Length=271, Percent_Identity=29.1512915129151, Blast_Score=134, Evalue=7e-32, Organism=Caenorhabditis elegans, GI17552492, Length=282, Percent_Identity=29.0780141843972, Blast_Score=133, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17561300, Length=255, Percent_Identity=31.3725490196078, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI17562292, Length=280, Percent_Identity=26.0714285714286, Blast_Score=110, Evalue=1e-24, Organism=Saccharomyces cerevisiae, GI6320576, Length=287, Percent_Identity=34.1463414634146, Blast_Score=165, Evalue=7e-42, Organism=Saccharomyces cerevisiae, GI6322556, Length=280, Percent_Identity=33.9285714285714, Blast_Score=164, Evalue=2e-41, Organism=Saccharomyces cerevisiae, GI6324694, Length=287, Percent_Identity=33.4494773519164, Blast_Score=162, Evalue=7e-41, Organism=Saccharomyces cerevisiae, GI6321896, Length=304, Percent_Identity=29.2763157894737, Blast_Score=140, Evalue=3e-34, Organism=Saccharomyces cerevisiae, GI6320079, Length=280, Percent_Identity=31.7857142857143, Blast_Score=125, Evalue=7e-30, Organism=Saccharomyces cerevisiae, GI6319625, Length=291, Percent_Identity=30.5841924398625, Blast_Score=120, Evalue=3e-28, Organism=Drosophila melanogaster, GI24663317, Length=280, Percent_Identity=36.0714285714286, Blast_Score=175, Evalue=3e-44, Organism=Drosophila melanogaster, GI45553081, Length=305, Percent_Identity=30.8196721311475, Blast_Score=159, Evalue=2e-39, Organism=Drosophila melanogaster, GI24657054, Length=283, Percent_Identity=36.0424028268551, Blast_Score=157, Evalue=9e-39, Organism=Drosophila melanogaster, GI20129731, Length=305, Percent_Identity=31.8032786885246, Blast_Score=155, Evalue=2e-38, Organism=Drosophila melanogaster, GI24644950, Length=300, Percent_Identity=33.3333333333333, Blast_Score=151, Evalue=4e-37, Organism=Drosophila melanogaster, GI24662789, Length=294, Percent_Identity=30.952380952381, Blast_Score=151, Evalue=6e-37, Organism=Drosophila melanogaster, GI21356425, Length=288, Percent_Identity=32.2916666666667, Blast_Score=145, Evalue=2e-35, Organism=Drosophila melanogaster, GI221378297, Length=320, Percent_Identity=31.875, Blast_Score=145, Evalue=3e-35, Organism=Drosophila melanogaster, GI24662781, Length=290, Percent_Identity=33.1034482758621, Blast_Score=137, Evalue=5e-33, Organism=Drosophila melanogaster, GI24662785, Length=287, Percent_Identity=33.4494773519164, Blast_Score=135, Evalue=3e-32, Organism=Drosophila melanogaster, GI281366140, Length=271, Percent_Identity=29.1512915129151, Blast_Score=124, Evalue=9e-29,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 32592; Mature: 32592
Theoretical pI: Translated: 4.89; Mature: 4.89
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTFKLNNGVEIPVLGFGVFQIPQEQTKQAVLDAIEVGYRHFDTAQSYFNEEEVGDAIAE CCEEECCCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH TIIPRENLFITTKVWLSNYGYENTKTSIKISLEKMKLDYLDLVLLHQPFGDVFGSYKALV HHCCCCCEEEEEEHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHH DLQKEGKIRAIGVSNFNELRLADIISFQDTVPQINQIEINPFHQREEDLQNALSRGNVQL HHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHCCEEE EAWAPFAEGKNGIFENEILSVIGKKYGKSPAQVILRWLYERGIVSLAKSVKKDRMKQNID EEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC IFNFSLTSEDKEQIGTLQTSGSQFFDHDDPKTVDFFEKLVKEREI EEEEEECCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC >Mature Secondary Structure MKTFKLNNGVEIPVLGFGVFQIPQEQTKQAVLDAIEVGYRHFDTAQSYFNEEEVGDAIAE CCEEECCCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH TIIPRENLFITTKVWLSNYGYENTKTSIKISLEKMKLDYLDLVLLHQPFGDVFGSYKALV HHCCCCCEEEEEEHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHH DLQKEGKIRAIGVSNFNELRLADIISFQDTVPQINQIEINPFHQREEDLQNALSRGNVQL HHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHCCEEE EAWAPFAEGKNGIFENEILSVIGKKYGKSPAQVILRWLYERGIVSLAKSVKKDRMKQNID EEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC IFNFSLTSEDKEQIGTLQTSGSQFFDHDDPKTVDFFEKLVKEREI EEEEEECCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA