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The map label for this gene is ceo [H]

Identifier: 125624063

GI number: 125624063

Start: 1207355

End: 1208293

Strand: Direct

Name: ceo [H]

Synonym: llmg_1237

Alternate gene names: 125624063

Gene position: 1207355-1208293 (Clockwise)

Preceding gene: 125624062

Following gene: 125624064

Centisome position: 47.73

GC content: 33.55

Gene sequence:

>939_bases
ATGATCTTAGGAATACTAAAATCTAATTTCCCAGGAGAGCGACGTGTCCCTCTCTTACCGGAAGATATCAATGATTTTGA
AAATGAATTGATATTAGAGGAAGGTTTTGGAGAAATGTTAGATATTGAAGATAATGCTTATAAGGAAGTCGGATGTCTTA
TTGCCTCTAGAGCAGAAGTCTTTGCAAAATCCGATGCGATATTTTCGTTGAAATTACTTCAGCCTGTTGATTATCCATCA
ATCAAAGTTGGTCAACTTATAATTGGATGGACTCATCCTCATGGTTCAGGTAAAAACTTTATGAACGACCAAGCTTTTCC
TAAAGATTTGGTCGTTGTTGATTTAGATAATAATTTTCCAGGAATTTTTTATAAAAATGAAGTCATTAGTGCAAATATTC
CCAAGGGGTTATTTTATAGAAATAGCTTTTATGCAGGACTTGCAGGAGTAATTCATGCCTTTACTTCGTATGGATTTTTA
CCAGATAATGAAACGAAAATTGCGATTCTTGGTTCTGGGAATGTTTCTCAGGGAGCGTTTAATAGTGCCTCAAAATTTTC
ATCTAATATTCGGATGTTTTATCGTAACACCATGCCAGTCTTTAAAAAGAATTTCAGGGATTATGATATCATTATTAATG
GCATTGAAGTTGGAACTGAGAACGACCCGATCCTATCACTCTTGGAACAGAGTCAGTTAAAAAAAGGAACATTAATTATT
GACGTGGCTGCTGATGCAGGAAATGCTATTCAAGGGAGCCATTTCACGGATATAGAGTATCCAATTTATAAAGAAAAAGG
ACTTTATTATTATGTTGTCCCAAATGTTCCTTCTATTTTTCATCGAAATATCAGTCAGTTATTAAGTAAGGTACTGAGTG
AACATATTTTTCGAAAAGATGTTGTTATTTTTAATGAAATAAAAGAAAGAAGAAAATGA

Upstream 100 bases:

>100_bases
CAGTTTGCAAAAACCTTGGGAAAAGGAACTAAAAATTCCTATAAAAGAGCTTATTAATGATTTAGAATTAGAAATAAGTT
ACAAAGAAGAGGTAAGTTAC

Downstream 100 bases:

>100_bases
AAGTTTTGCGATATTTCAATTGGAAAAATACTTCAGGATGTTTTTTAATACATTTGCGAGAGGATTCCAATTTTATATAG
AATCAAATATTCTGATGGAC

Product: N5-carboxyethyl-ornithine synthase

Products: NA

Alternate protein names: CEOS; N(5)-(L-1-carboxyethyl)-L-ornithine:NADP(+) oxidoreductase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MILGILKSNFPGERRVPLLPEDINDFENELILEEGFGEMLDIEDNAYKEVGCLIASRAEVFAKSDAIFSLKLLQPVDYPS
IKVGQLIIGWTHPHGSGKNFMNDQAFPKDLVVVDLDNNFPGIFYKNEVISANIPKGLFYRNSFYAGLAGVIHAFTSYGFL
PDNETKIAILGSGNVSQGAFNSASKFSSNIRMFYRNTMPVFKKNFRDYDIIINGIEVGTENDPILSLLEQSQLKKGTLII
DVAADAGNAIQGSHFTDIEYPIYKEKGLYYYVVPNVPSIFHRNISQLLSKVLSEHIFRKDVVIFNEIKERRK

Sequences:

>Translated_312_residues
MILGILKSNFPGERRVPLLPEDINDFENELILEEGFGEMLDIEDNAYKEVGCLIASRAEVFAKSDAIFSLKLLQPVDYPS
IKVGQLIIGWTHPHGSGKNFMNDQAFPKDLVVVDLDNNFPGIFYKNEVISANIPKGLFYRNSFYAGLAGVIHAFTSYGFL
PDNETKIAILGSGNVSQGAFNSASKFSSNIRMFYRNTMPVFKKNFRDYDIIINGIEVGTENDPILSLLEQSQLKKGTLII
DVAADAGNAIQGSHFTDIEYPIYKEKGLYYYVVPNVPSIFHRNISQLLSKVLSEHIFRKDVVIFNEIKERRK
>Mature_312_residues
MILGILKSNFPGERRVPLLPEDINDFENELILEEGFGEMLDIEDNAYKEVGCLIASRAEVFAKSDAIFSLKLLQPVDYPS
IKVGQLIIGWTHPHGSGKNFMNDQAFPKDLVVVDLDNNFPGIFYKNEVISANIPKGLFYRNSFYAGLAGVIHAFTSYGFL
PDNETKIAILGSGNVSQGAFNSASKFSSNIRMFYRNTMPVFKKNFRDYDIIINGIEVGTENDPILSLLEQSQLKKGTLII
DVAADAGNAIQGSHFTDIEYPIYKEKGLYYYVVPNVPSIFHRNISQLLSKVLSEHIFRKDVVIFNEIKERRK

Specific function: Catalyzes the NADPH-dependent reductive condensation between pyruvic acid and the side chain amino group of L-ornithine to form N(5)-(L-1-carboxyethyl)-L-ornithine. To a lesser extent, can also use L-lysine as substrate (yielding N(6)-(L-1- carboxyethyl)-

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family. CEOS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR007886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.5.1.24 [H]

Molecular weight: Translated: 35119; Mature: 35119

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGILKSNFPGERRVPLLPEDINDFENELILEEGFGEMLDIEDNAYKEVGCLIASRAEV
CEEEEECCCCCCCCCCCCCCHHHHHHHHHEEHCCCCCCEEECCCCHHHHHHHHHHHHHHH
FAKSDAIFSLKLLQPVDYPSIKVGQLIIGWTHPHGSGKNFMNDQAFPKDLVVVDLDNNFP
HCCCCCEEEEEEECCCCCCCEEECEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCC
GIFYKNEVISANIPKGLFYRNSFYAGLAGVIHAFTSYGFLPDNETKIAILGSGNVSQGAF
CEEEECCEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
NSASKFSSNIRMFYRNTMPVFKKNFRDYDIIINGIEVGTENDPILSLLEQSQLKKGTLII
CCHHHHHCCEEEEEECCCHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCCEEE
DVAADAGNAIQGSHFTDIEYPIYKEKGLYYYVVPNVPSIFHRNISQLLSKVLSEHIFRKD
EEECCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVIFNEIKERRK
HHHHHHHHHHCC
>Mature Secondary Structure
MILGILKSNFPGERRVPLLPEDINDFENELILEEGFGEMLDIEDNAYKEVGCLIASRAEV
CEEEEECCCCCCCCCCCCCCHHHHHHHHHEEHCCCCCCEEECCCCHHHHHHHHHHHHHHH
FAKSDAIFSLKLLQPVDYPSIKVGQLIIGWTHPHGSGKNFMNDQAFPKDLVVVDLDNNFP
HCCCCCEEEEEEECCCCCCCEEECEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCC
GIFYKNEVISANIPKGLFYRNSFYAGLAGVIHAFTSYGFLPDNETKIAILGSGNVSQGAF
CEEEECCEEECCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
NSASKFSSNIRMFYRNTMPVFKKNFRDYDIIINGIEVGTENDPILSLLEQSQLKKGTLII
CCHHHHHCCEEEEEECCCHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCCCEEE
DVAADAGNAIQGSHFTDIEYPIYKEKGLYYYVVPNVPSIFHRNISQLLSKVLSEHIFRKD
EEECCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVIFNEIKERRK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7744873; 2498334; 10548058; 10525296 [H]