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The map label for this gene is aguA [H]

Identifier: 125623999

GI number: 125623999

Start: 1133781

End: 1135775

Strand: Direct

Name: aguA [H]

Synonym: llmg_1169

Alternate gene names: 125623999

Gene position: 1133781-1135775 (Clockwise)

Preceding gene: 125623998

Following gene: 125624000

Centisome position: 44.82

GC content: 39.25

Gene sequence:

>1995_bases
ATGGCGATAGATGAAATGTGGCTACAGTTTTCAATACTGAAAAAACGACTGACCAATGAGATTTTCTATGTGAATCTGGA
GTATGAGGATAAAATTACGATTCGCTTGCGCTCAGAAATCTGTGAATGGTTAGGTTGTCAGCTGACAGGAGAAAAGTCAG
AAGCAACAGTGGTCTTGTCAGTAAATAGTAAGCTAGATGATAACTTGGAAGCTTATGAGGTCAAAGAAAATGAGATTATT
GGCGCTTCGTCAGTTGGTTTGCTTTATGGATTTTATGCTTATTTGCGCTTAAAGCTGTCAGGAGCCAACTTATCTGAAAA
ATCAGCACCTGCTCAATCTTTGCGAATGATTAATCATTGGGATCAAGTGGATGGAACTATTGAGCGTGGCTATGCTGGTG
AGTCTATTTTCTTTGGTCGCTTTGGTTCAAATGACAATACAGACACAGGTTCTTTTGCTGTAAAAAATATTGGAACAGAC
ATCTTTCGTAATGATTTCACGCGCTTGAAAATGTATGCTCGCTTTCTTGCTTCAATTGGAATTAATGCGATTTCGCTTAA
TAATGTAAATGTTCGAGGGCTAGGAACAAGTTTGATTGTCTCACCTTACATTGAGAAAGTAGGGGAAATTTCTAAACTTT
TTGCTACTTTTGGTCTAAAGACTTTCTTAGCCATTAATTGGGCAGCACCAAAATTGATTGGTGAGCTAAAAACGTCTGAC
CCCTTGGATGAAAATGTATATACATGGTGGCAACAAACCATTGACCATATCTATGAAGTCATTCCTGATTTTGGTGGTTT
TGTCGTTAAGGCAGATTCTGAGGGTGAACCTGGTCCTTATCAATATGGTCGAAATCATGCTGACGGGGCCAATATGCTAG
CGAAAGCTTTTGAAAAATATAATGGACTTGTCATTTGGCGAACTTTTGTATATAATTCTCAGACTGATTGGCGGAAGCGT
AAAAATGACCGAGCTAAGGCAGCTTATGAAAACTTCATGCCTCTTGATGGTGATTTTTCTGACAATGTGATTTTACAGAT
TAAGTTTGGACCTATTGATTTTGGAGTGAGAGAACCCTTGATGCCCTTGTTTGGGGCACTTAAAAAGACTAATCAATTAA
TGGAATTTCAAATCACAGCCGAGTATTTAGGGCATCAACTTGACCTGAACTATGTTCTTCCTCAATGGTTGGAAATGATT
CATTTTGATAACTATGGTCAGCCAAAAGACACGATAAGGGCTAATTCTCCAGTCGCGACTCATTCAGGTTTTATTGCCAT
TGGCAATGTGGGAATGGACGAAAATTGGTGCGGGAATAAGCTATCCCAAGCTAATTTTTATGGTTTTGGCCGCATGTGTT
GGAACAATGATTTGACAGCGACTGAGATTTTGCAAGAATGGATTGCATTGACTTTTTCAGAAGTAAAAGCAGAGGTCCAA
AAAGAGATTTTTGAGCTCCTGATTGATTCTAATCAAACTTATGAACTCTACAACGCCCCGCTTGCTGTGGGCTCAATGAT
GGTTCCTCATTATCATTATGGGCCTTCAATCAATGGTTATGAGTATGATCGTTGGGGCGCTTATCATTTTTCCGACCGCA
ACGGTCTTGGTATTGACCGAACGACTGCGACTGGAACGGGCTTTGCTAGTCTTTACGCGCCAGAAGTAGCCAAGGTTTTT
GAAGATAAAAGCAAAACTCCGGATGAAATTCTACTCTTTTTCCATTATGTTGAATATGGTCATCTTTTGCATAATGGAAA
GACATTGATTCAAACTATTTATGACCAACATTTTGAAGGTTTTGAACGCGTTAAATCTTATATCAAAAGCTGGAAATCTT
TGAAGGGGCAAGTTGATGAAGCAACTTATGATAATGTTGCCGATCGTTTAGAGCGTCAACTGGAACATGCCAGAAATTGG
CGAGACCAAGTTAATACTTATTTTTATCGAATGTCTGGTATTCCAGATGATCAAGGTCGGGAGATTTATCGGTGA

Upstream 100 bases:

>100_bases
ACTTAATGATGAAGCTTATATTTATTATTCACGTGATAAGCGAGCGAAAACAGGTTTTGGTGGAAGTTGAACTTATTGGT
CAAATGGAAAGGGTTAAAAA

Downstream 100 bases:

>100_bases
TTTTAGAAAAATAGCTAATATGATGATATTAGCTATTTTTGCTTAAGTGATTTATTTTAGAAGTATTATTAAAATGTTTA
TCTGATATAATAGATTTAGA

Product: AguA protein

Products: NA

Alternate protein names: Alpha-glucosiduronase [H]

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MAIDEMWLQFSILKKRLTNEIFYVNLEYEDKITIRLRSEICEWLGCQLTGEKSEATVVLSVNSKLDDNLEAYEVKENEII
GASSVGLLYGFYAYLRLKLSGANLSEKSAPAQSLRMINHWDQVDGTIERGYAGESIFFGRFGSNDNTDTGSFAVKNIGTD
IFRNDFTRLKMYARFLASIGINAISLNNVNVRGLGTSLIVSPYIEKVGEISKLFATFGLKTFLAINWAAPKLIGELKTSD
PLDENVYTWWQQTIDHIYEVIPDFGGFVVKADSEGEPGPYQYGRNHADGANMLAKAFEKYNGLVIWRTFVYNSQTDWRKR
KNDRAKAAYENFMPLDGDFSDNVILQIKFGPIDFGVREPLMPLFGALKKTNQLMEFQITAEYLGHQLDLNYVLPQWLEMI
HFDNYGQPKDTIRANSPVATHSGFIAIGNVGMDENWCGNKLSQANFYGFGRMCWNNDLTATEILQEWIALTFSEVKAEVQ
KEIFELLIDSNQTYELYNAPLAVGSMMVPHYHYGPSINGYEYDRWGAYHFSDRNGLGIDRTTATGTGFASLYAPEVAKVF
EDKSKTPDEILLFFHYVEYGHLLHNGKTLIQTIYDQHFEGFERVKSYIKSWKSLKGQVDEATYDNVADRLERQLEHARNW
RDQVNTYFYRMSGIPDDQGREIYR

Sequences:

>Translated_664_residues
MAIDEMWLQFSILKKRLTNEIFYVNLEYEDKITIRLRSEICEWLGCQLTGEKSEATVVLSVNSKLDDNLEAYEVKENEII
GASSVGLLYGFYAYLRLKLSGANLSEKSAPAQSLRMINHWDQVDGTIERGYAGESIFFGRFGSNDNTDTGSFAVKNIGTD
IFRNDFTRLKMYARFLASIGINAISLNNVNVRGLGTSLIVSPYIEKVGEISKLFATFGLKTFLAINWAAPKLIGELKTSD
PLDENVYTWWQQTIDHIYEVIPDFGGFVVKADSEGEPGPYQYGRNHADGANMLAKAFEKYNGLVIWRTFVYNSQTDWRKR
KNDRAKAAYENFMPLDGDFSDNVILQIKFGPIDFGVREPLMPLFGALKKTNQLMEFQITAEYLGHQLDLNYVLPQWLEMI
HFDNYGQPKDTIRANSPVATHSGFIAIGNVGMDENWCGNKLSQANFYGFGRMCWNNDLTATEILQEWIALTFSEVKAEVQ
KEIFELLIDSNQTYELYNAPLAVGSMMVPHYHYGPSINGYEYDRWGAYHFSDRNGLGIDRTTATGTGFASLYAPEVAKVF
EDKSKTPDEILLFFHYVEYGHLLHNGKTLIQTIYDQHFEGFERVKSYIKSWKSLKGQVDEATYDNVADRLERQLEHARNW
RDQVNTYFYRMSGIPDDQGREIYR
>Mature_663_residues
AIDEMWLQFSILKKRLTNEIFYVNLEYEDKITIRLRSEICEWLGCQLTGEKSEATVVLSVNSKLDDNLEAYEVKENEIIG
ASSVGLLYGFYAYLRLKLSGANLSEKSAPAQSLRMINHWDQVDGTIERGYAGESIFFGRFGSNDNTDTGSFAVKNIGTDI
FRNDFTRLKMYARFLASIGINAISLNNVNVRGLGTSLIVSPYIEKVGEISKLFATFGLKTFLAINWAAPKLIGELKTSDP
LDENVYTWWQQTIDHIYEVIPDFGGFVVKADSEGEPGPYQYGRNHADGANMLAKAFEKYNGLVIWRTFVYNSQTDWRKRK
NDRAKAAYENFMPLDGDFSDNVILQIKFGPIDFGVREPLMPLFGALKKTNQLMEFQITAEYLGHQLDLNYVLPQWLEMIH
FDNYGQPKDTIRANSPVATHSGFIAIGNVGMDENWCGNKLSQANFYGFGRMCWNNDLTATEILQEWIALTFSEVKAEVQK
EIFELLIDSNQTYELYNAPLAVGSMMVPHYHYGPSINGYEYDRWGAYHFSDRNGLGIDRTTATGTGFASLYAPEVAKVFE
DKSKTPDEILLFFHYVEYGHLLHNGKTLIQTIYDQHFEGFERVKSYIKSWKSLKGQVDEATYDNVADRLERQLEHARNWR
DQVNTYFYRMSGIPDDQGREIYR

Specific function: Releases 4-O-methylglucuronic acid from substituted xylo-oligosaccharides [H]

COG id: COG3661

COG function: function code G; Alpha-glucuronidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 67 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011395
- InterPro:   IPR005154
- InterPro:   IPR011099
- InterPro:   IPR011100
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF07477 Glyco_hydro_67C; PF07488 Glyco_hydro_67M; PF03648 Glyco_hydro_67N [H]

EC number: =3.2.1.139 [H]

Molecular weight: Translated: 75975; Mature: 75844

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDEMWLQFSILKKRLTNEIFYVNLEYEDKITIRLRSEICEWLGCQLTGEKSEATVVLS
CCHHHHHHHHHHHHHHHCCCEEEEEEEECCEEEEEEHHHHHHHHCCEEECCCCCEEEEEE
VNSKLDDNLEAYEVKENEIIGASSVGLLYGFYAYLRLKLSGANLSEKSAPAQSLRMINHW
ECCCCCCCCCEEEECCCCEECCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHH
DQVDGTIERGYAGESIFFGRFGSNDNTDTGSFAVKNIGTDIFRNDFTRLKMYARFLASIG
HHHCCHHHCCCCCCEEEEEECCCCCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHCC
INAISLNNVNVRGLGTSLIVSPYIEKVGEISKLFATFGLKTFLAINWAAPKLIGELKTSD
CCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHEEECCCHHHHHHCCCCC
PLDENVYTWWQQTIDHIYEVIPDFGGFVVKADSEGEPGPYQYGRNHADGANMLAKAFEKY
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHCCCCCCCHHHHHHHHHHHH
NGLVIWRTFVYNSQTDWRKRKNDRAKAAYENFMPLDGDFSDNVILQIKFGPIDFGVREPL
CCEEEEEEEEECCCCHHHHHHCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHH
MPLFGALKKTNQLMEFQITAEYLGHQLDLNYVLPQWLEMIHFDNYGQPKDTIRANSPVAT
HHHHHHHHHHCHHHEEEEEHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEE
HSGFIAIGNVGMDENWCGNKLSQANFYGFGRMCWNNDLTATEILQEWIALTFSEVKAEVQ
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
KEIFELLIDSNQTYELYNAPLAVGSMMVPHYHYGPSINGYEYDRWGAYHFSDRNGLGIDR
HHHHHHHHCCCCCEEEECCCHHHHHEECCCEECCCCCCCCCCCCCCCEEECCCCCCCCCC
TTATGTGFASLYAPEVAKVFEDKSKTPDEILLFFHYVEYGHLLHNGKTLIQTIYDQHFEG
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FERVKSYIKSWKSLKGQVDEATYDNVADRLERQLEHARNWRDQVNTYFYRMSGIPDDQGR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
EIYR
CCCC
>Mature Secondary Structure 
AIDEMWLQFSILKKRLTNEIFYVNLEYEDKITIRLRSEICEWLGCQLTGEKSEATVVLS
CHHHHHHHHHHHHHHHCCCEEEEEEEECCEEEEEEHHHHHHHHCCEEECCCCCEEEEEE
VNSKLDDNLEAYEVKENEIIGASSVGLLYGFYAYLRLKLSGANLSEKSAPAQSLRMINHW
ECCCCCCCCCEEEECCCCEECCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHH
DQVDGTIERGYAGESIFFGRFGSNDNTDTGSFAVKNIGTDIFRNDFTRLKMYARFLASIG
HHHCCHHHCCCCCCEEEEEECCCCCCCCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHCC
INAISLNNVNVRGLGTSLIVSPYIEKVGEISKLFATFGLKTFLAINWAAPKLIGELKTSD
CCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHEEECCCHHHHHHCCCCC
PLDENVYTWWQQTIDHIYEVIPDFGGFVVKADSEGEPGPYQYGRNHADGANMLAKAFEKY
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHCCCCCCCHHHHHHHHHHHH
NGLVIWRTFVYNSQTDWRKRKNDRAKAAYENFMPLDGDFSDNVILQIKFGPIDFGVREPL
CCEEEEEEEEECCCCHHHHHHCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHH
MPLFGALKKTNQLMEFQITAEYLGHQLDLNYVLPQWLEMIHFDNYGQPKDTIRANSPVAT
HHHHHHHHHHCHHHEEEEEHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEE
HSGFIAIGNVGMDENWCGNKLSQANFYGFGRMCWNNDLTATEILQEWIALTFSEVKAEVQ
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
KEIFELLIDSNQTYELYNAPLAVGSMMVPHYHYGPSINGYEYDRWGAYHFSDRNGLGIDR
HHHHHHHHCCCCCEEEECCCHHHHHEECCCEECCCCCCCCCCCCCCCEEECCCCCCCCCC
TTATGTGFASLYAPEVAKVFEDKSKTPDEILLFFHYVEYGHLLHNGKTLIQTIYDQHFEG
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FERVKSYIKSWKSLKGQVDEATYDNVADRLERQLEHARNWRDQVNTYFYRMSGIPDDQGR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCC
EIYR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9044261; 10360571 [H]