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The map label for this gene is sbcD [H]

Identifier: 125623963

GI number: 125623963

Start: 1096630

End: 1097802

Strand: Direct

Name: sbcD [H]

Synonym: llmg_1132

Alternate gene names: 125623963

Gene position: 1096630-1097802 (Clockwise)

Preceding gene: 125623962

Following gene: 125623964

Centisome position: 43.35

GC content: 33.16

Gene sequence:

>1173_bases
ATGAAGTTTTTACATACGTCAGATTGGCACATTGGGAGAACGATAAATGGTTTTTCATTATTAGAAGAGCAAAAATATGC
CTTTAAACAAATTCTTTCTCTGGCAAAAGAATATGAAGTTGATGGAATAATTATTGCTGGAGATTTGTATGACCGAGCGG
TTCCAAGTGCAGATTCTGTTATTACTTTTAATCAAATGTTAAGAGAAATGAACATCATCGAAAAATTTCCAATTTATGCA
ATTTCAGGAAATCATGATGGGGCCAAGAGATTAAATTATGCCAAAGAATGGTTGGATTTTAATCAATTACATTTACGGAC
TTCTTTAGAGGAAGCTTTTATTCCAATTGAAACTGAGCAAGTTCAATTATTTTTATTACCTTTTTTTGATCCGATGGATG
CAAGGATATACTTTTCAAGTCAGGGTCAGGACGAGGAAAAAGCAAAAGAGATCAAAACTATTGATGAAGCAATGACCTTA
GTTATTTCTGAAATGCAAACACATTTTGATAAAAACAAAAAGCAAATTTTAGTGACACATTTTGCGGTAAGTCCTCATAA
AGAAGAGATTAACTTAACAAGTGAAACTACCTCAAAAGTGGGTGGTTTAGCAACTTTAAATGTTATTCAATTCGAAGCGT
TTGATTATGTGGCCTTAGGACACATCCACACTAGATTTGCTTCACCCAGTGAGAAGGTACAGTATTCTGGAAGTCCAGTA
AAATTTAACACAAAAGAAGCAAAAACTCAAAAGGGAGTTTTTATTGTAGAAACACAGCAAGATTCCGTCAGCTCTGAGTT
TATTCCTTTACAAATCCAAACGGATTTAGTTGTTATTGAAGAAGAGTGGGACACCTTAATCAGTCGAGAGTTTTACGAAA
ATCAGCCAATTCATCAAGCTTGGTTCGCTATCACCATAAAAAACTTTGATAGAGCAAAACTTGCAGGACGAAATTTACGT
GCCCAACTTCAAAAAGTATATGGAACCATAGTGGAATTGGATTATAAATTTAAAAATATTTCGTCAGTAAAAAGTAAAAC
TCAAAATATTGAAAGCTTGGATAATATTGGGATACTTTCAAATTTTTATGAAGTTACAACTGGTGAGACTTTAAGTGGCT
TGCAGCAAGAAATTATTGAGAACACGTTCAAACAAATAGAAGGAGAAAAATAA

Upstream 100 bases:

>100_bases
TTGTTTTCTTTAGGGATGAGGATAACAATCTGGTAGCAAACAAACTAAAGTTTTTTTGATAATGTTATAATAATAATTAA
ATTCACTTGGGGAGATAAAT

Downstream 100 bases:

>100_bases
TAATGAAACCTATATATTTAGAAATGAATTATTTTGGTCCTCATGAGAAATCTATCGTTGATTTCCGTCTATTAGATGAA
TCGCCTATTTTTCTAATTAG

Product: nuclease SbcCD subunit D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKFLHTSDWHIGRTINGFSLLEEQKYAFKQILSLAKEYEVDGIIIAGDLYDRAVPSADSVITFNQMLREMNIIEKFPIYA
ISGNHDGAKRLNYAKEWLDFNQLHLRTSLEEAFIPIETEQVQLFLLPFFDPMDARIYFSSQGQDEEKAKEIKTIDEAMTL
VISEMQTHFDKNKKQILVTHFAVSPHKEEINLTSETTSKVGGLATLNVIQFEAFDYVALGHIHTRFASPSEKVQYSGSPV
KFNTKEAKTQKGVFIVETQQDSVSSEFIPLQIQTDLVVIEEEWDTLISREFYENQPIHQAWFAITIKNFDRAKLAGRNLR
AQLQKVYGTIVELDYKFKNISSVKSKTQNIESLDNIGILSNFYEVTTGETLSGLQQEIIENTFKQIEGEK

Sequences:

>Translated_390_residues
MKFLHTSDWHIGRTINGFSLLEEQKYAFKQILSLAKEYEVDGIIIAGDLYDRAVPSADSVITFNQMLREMNIIEKFPIYA
ISGNHDGAKRLNYAKEWLDFNQLHLRTSLEEAFIPIETEQVQLFLLPFFDPMDARIYFSSQGQDEEKAKEIKTIDEAMTL
VISEMQTHFDKNKKQILVTHFAVSPHKEEINLTSETTSKVGGLATLNVIQFEAFDYVALGHIHTRFASPSEKVQYSGSPV
KFNTKEAKTQKGVFIVETQQDSVSSEFIPLQIQTDLVVIEEEWDTLISREFYENQPIHQAWFAITIKNFDRAKLAGRNLR
AQLQKVYGTIVELDYKFKNISSVKSKTQNIESLDNIGILSNFYEVTTGETLSGLQQEIIENTFKQIEGEK
>Mature_390_residues
MKFLHTSDWHIGRTINGFSLLEEQKYAFKQILSLAKEYEVDGIIIAGDLYDRAVPSADSVITFNQMLREMNIIEKFPIYA
ISGNHDGAKRLNYAKEWLDFNQLHLRTSLEEAFIPIETEQVQLFLLPFFDPMDARIYFSSQGQDEEKAKEIKTIDEAMTL
VISEMQTHFDKNKKQILVTHFAVSPHKEEINLTSETTSKVGGLATLNVIQFEAFDYVALGHIHTRFASPSEKVQYSGSPV
KFNTKEAKTQKGVFIVETQQDSVSSEFIPLQIQTDLVVIEEEWDTLISREFYENQPIHQAWFAITIKNFDRAKLAGRNLR
AQLQKVYGTIVELDYKFKNISSVKSKTQNIESLDNIGILSNFYEVTTGETLSGLQQEIIENTFKQIEGEK

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 44718; Mature: 44718

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLHTSDWHIGRTINGFSLLEEQKYAFKQILSLAKEYEVDGIIIAGDLYDRAVPSADSV
CCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCCCE
ITFNQMLREMNIIEKFPIYAISGNHDGAKRLNYAKEWLDFNQLHLRTSLEEAFIPIETEQ
EHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEECCC
VQLFLLPFFDPMDARIYFSSQGQDEEKAKEIKTIDEAMTLVISEMQTHFDKNKKQILVTH
EEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
FAVSPHKEEINLTSETTSKVGGLATLNVIQFEAFDYVALGHIHTRFASPSEKVQYSGSPV
EECCCCCCCEEECHHHHHHHCCEEEEEEEEEECCCEEEEHHHHHHCCCCCHHEEECCCCE
KFNTKEAKTQKGVFIVETQQDSVSSEFIPLQIQTDLVVIEEEWDTLISREFYENQPIHQA
EECCHHHHHHCCEEEEEECCCCCCCCEEEEEEECCEEEEECHHHHHHHHHHHCCCCCCCE
WFAITIKNFDRAKLAGRNLRAQLQKVYGTIVELDYKFKNISSVKSKTQNIESLDNIGILS
EEEEEECCCCHHHHCCCHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCHHHH
NFYEVTTGETLSGLQQEIIENTFKQIEGEK
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKFLHTSDWHIGRTINGFSLLEEQKYAFKQILSLAKEYEVDGIIIAGDLYDRAVPSADSV
CCCEECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCCCE
ITFNQMLREMNIIEKFPIYAISGNHDGAKRLNYAKEWLDFNQLHLRTSLEEAFIPIETEQ
EHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEECCC
VQLFLLPFFDPMDARIYFSSQGQDEEKAKEIKTIDEAMTLVISEMQTHFDKNKKQILVTH
EEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
FAVSPHKEEINLTSETTSKVGGLATLNVIQFEAFDYVALGHIHTRFASPSEKVQYSGSPV
EECCCCCCCEEECHHHHHHHCCEEEEEEEEEECCCEEEEHHHHHHCCCCCHHEEECCCCE
KFNTKEAKTQKGVFIVETQQDSVSSEFIPLQIQTDLVVIEEEWDTLISREFYENQPIHQA
EECCHHHHHHCCEEEEEECCCCCCCCEEEEEEECCEEEEECHHHHHHHHHHHCCCCCCCE
WFAITIKNFDRAKLAGRNLRAQLQKVYGTIVELDYKFKNISSVKSKTQNIESLDNIGILS
EEEEEECCCCHHHHCCCHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCHHHH
NFYEVTTGETLSGLQQEIIENTFKQIEGEK
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA