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The map label for this gene is nagA [H]

Identifier: 125623948

GI number: 125623948

Start: 1076647

End: 1077795

Strand: Direct

Name: nagA [H]

Synonym: llmg_1117

Alternate gene names: 125623948

Gene position: 1076647-1077795 (Clockwise)

Preceding gene: 125623947

Following gene: 125623949

Centisome position: 42.56

GC content: 42.56

Gene sequence:

>1149_bases
ATGACTTACTATATTAAAGCAGATCAATTTTTCTACGCTTATGAAACAAAAAAAGGTGGTTTCTTAGAAATTACTGATGG
AAAATTTGGAGAGTGGACAGAAGAAGCGCCAGCAGGAGCTGAAATCTTAGATTATTCAGGACAATCTATTGCCCCAGGAT
TAGTTGAAACACATATTCATGGTTTCGGTGGTGCAGATGCCCAAGATGCTGAAGTAGAAGGAACCATGGGGACAATGTCA
GAAGGATTATTGTCAGCAGGAGTTACTTCATTTTTGCCAAGTCCTTTAACAGATGACCATGAAGGCTTGAAAGCGGTCTG
TACAGTTGTAGGAGAACACTACCAAGAAGCACGCGGAGCTAAAGTACGTGGAATTTTCTTTGAAGGTCCTTTCTTTACAG
AAGAAAAGAAAGGGGCTCAAAACCCTAAATACATGCGTGATGCTAAAATGTGGGAGCTTGAAGATTGGCAAGAAGCTGCA
CATGGAATGCTTAAGAAAATTGGTCTTGCACCAGAACGCGAAGGTTCAGAAGACTTTATTCGTAAGGCGACTGAATCAGG
GGTTGTCATTGCCTTAGGCCATTCGAACGCGACATATAAGCAAGCAGTTGCCGGTGTTCAAGCTGGAGCATCTGTATGGG
TTCACACATTCAATGGGATGTCAGGAATGACTCACCAAGAACCAGGGATGGTTGGAGCAATTTTAAATACTCCAAATACT
TACGCTGAATTAATTTGTGATGGTCACCATGTTCGTCCAGAAGCCGCTGAAATTGTTGTGAAAATGAAAGGCGCTGACCA
TGTTGTTTTGATTACAGACTCAATGCGTGCCGCAGGACTTCCTGATGGTCCTTATATGCTTGGAGAATACGAAGTAGAAG
TGCGCGATGGCGCTGCTTGGCTTCCAACAGGCCGCCCAGCCGCTTCAATTTTAACACTTAAAACAGCCGTTAAAAATGTG
ATTGACTGGGGGATTGCTACGCCAGCAGAAGCAGTTATGATGGCTTCATTAACGCCAGCAAAATCAGTAAATATTGATGA
TGTTTGTGGACAAATCAAACCAGGACTTGCAGCCGATTTCATCGTATTAGACAATGAATATGATTTAGTTGCGACTTATC
TTGATGGTGAAAAACGTTACGAAGCTTAA

Upstream 100 bases:

>100_bases
AGCTGTCAGTAATTTTTTCATTCTGATAATTGGTATATACTGTTTATTGACAAAAAAGATAAAGGGTGCTAAAATTAAAG
AAAAAGAAGAGGAGATATTT

Downstream 100 bases:

>100_bases
TCTTGAAAATGAATTTCGAAAGGAATTCATTTTTTTATGAAAATAATTTCAATTTTCAAAATGAATAATTAGAAAAATAA
ACAAAAAAGTAAAAGATTCT

Product: NagA protein

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGAEILDYSGQSIAPGLVETHIHGFGGADAQDAEVEGTMGTMS
EGLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGAKVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAA
HGMLKKIGLAPEREGSEDFIRKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNT
YAELICDGHHVRPEAAEIVVKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAWLPTGRPAASILTLKTAVKNV
IDWGIATPAEAVMMASLTPAKSVNIDDVCGQIKPGLAADFIVLDNEYDLVATYLDGEKRYEA

Sequences:

>Translated_382_residues
MTYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGAEILDYSGQSIAPGLVETHIHGFGGADAQDAEVEGTMGTMS
EGLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGAKVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAA
HGMLKKIGLAPEREGSEDFIRKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNT
YAELICDGHHVRPEAAEIVVKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAWLPTGRPAASILTLKTAVKNV
IDWGIATPAEAVMMASLTPAKSVNIDDVCGQIKPGLAADFIVLDNEYDLVATYLDGEKRYEA
>Mature_381_residues
TYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGAEILDYSGQSIAPGLVETHIHGFGGADAQDAEVEGTMGTMSE
GLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGAKVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAAH
GMLKKIGLAPEREGSEDFIRKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNTY
AELICDGHHVRPEAAEIVVKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAWLPTGRPAASILTLKTAVKNVI
DWGIATPAEAVMMASLTPAKSVNIDDVCGQIKPGLAADFIVLDNEYDLVATYLDGEKRYEA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=394, Percent_Identity=29.9492385786802, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI224922791, Length=386, Percent_Identity=30.0518134715026, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1786892, Length=382, Percent_Identity=28.7958115183246, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17553768, Length=398, Percent_Identity=25.8793969849246, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI19920392, Length=344, Percent_Identity=30.5232558139535, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281361140, Length=358, Percent_Identity=29.608938547486, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41162; Mature: 41031

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGAEILDYSGQSIAPGLVETHIH
CEEEEEECEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCC
GFGGADAQDAEVEGTMGTMSEGLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGA
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
KVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAAHGMLKKIGLAPEREGSEDFI
EEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
RKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNT
HHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCH
YAELICDGHHVRPEAAEIVVKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAW
HHHHEECCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEEEEEECCEEE
LPTGRPAASILTLKTAVKNVIDWGIATPAEAVMMASLTPAKSVNIDDVCGQIKPGLAADF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHEEECCCCCCCCHHHHHHCCCCCCEEEE
IVLDNEYDLVATYLDGEKRYEA
EEECCCCEEEEEEECCCHHCCC
>Mature Secondary Structure 
TYYIKADQFFYAYETKKGGFLEITDGKFGEWTEEAPAGAEILDYSGQSIAPGLVETHIH
EEEEEECEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCC
GFGGADAQDAEVEGTMGTMSEGLLSAGVTSFLPSPLTDDHEGLKAVCTVVGEHYQEARGA
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
KVRGIFFEGPFFTEEKKGAQNPKYMRDAKMWELEDWQEAAHGMLKKIGLAPEREGSEDFI
EEEEEEECCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHH
RKATESGVVIALGHSNATYKQAVAGVQAGASVWVHTFNGMSGMTHQEPGMVGAILNTPNT
HHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCH
YAELICDGHHVRPEAAEIVVKMKGADHVVLITDSMRAAGLPDGPYMLGEYEVEVRDGAAW
HHHHEECCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEEEEEECCEEE
LPTGRPAASILTLKTAVKNVIDWGIATPAEAVMMASLTPAKSVNIDDVCGQIKPGLAADF
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHEEECCCCCCCCHHHHHHCCCCCCEEEE
IVLDNEYDLVATYLDGEKRYEA
EEECCCCEEEEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]