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The map label for this gene is gpsA

Identifier: 125623945

GI number: 125623945

Start: 1073311

End: 1074339

Strand: Reverse

Name: gpsA

Synonym: llmg_1114

Alternate gene names: 125623945

Gene position: 1074339-1073311 (Counterclockwise)

Preceding gene: 125623952

Following gene: 125623944

Centisome position: 42.47

GC content: 39.46

Gene sequence:

>1029_bases
ATGAATCCACAAAAAATTGCAGTTTTAGGTCCAGGCTCATGGGGAACTGCTCTTTCACAAGTTCTTAATGATAATGGTCA
TGAAGTTCGTATCTGGGGAAACAACCTAGAACAAATGGCCGAGATAAATGAAAAACATACGAATACACGCTACTTTAAAG
ATGTTGTCTTAGATGAAAAAATAAAGGCATATAGTCGTTTAGATTTAGCTTTGGAAAATGTTGATGCCATCCTATTTGTT
GTGCCAACGAAAGTTACACGATTGGTTGCAAAACAAGTTGCCCAAGTTCTTAAACATAAAGTTCATATCCTACATGCTTC
AAAAGGGCTTGAACAAGGGACACATGACCGAATTTCGACAATTCTTGAAGAAGAAATTCCAGCTCAACTTCGCGGTGAAA
TCGTTGTCGTTTCTGGTCCTTCTCATGCTGAGGAAACGATTGTTCGTGACATCACTTTGATTTCTGCAGCTTCTAATGAT
CATGACGAAGCAAAATATGCTCAATCTATTTTTAGTAATGACTATTTCCGTCTTTATACTAATACTGATGTGATTGGAGT
TGAGACAGCTGGTGCTCTTAAAAACATTATCGCGGTTGGAGCAGGGGCATTACACGGTCTTGGTTTTGGTGACAATGCTA
AAGCAGCAATTATTACTCGTGGTCTTGCCGAGATTACTCGATTAGGCGTTGCCATGGGAGCTGAACCTTTAACTTACAGT
GGTCTTTCCGGAGTCGGCGACCTTATTGTAACAGGGACGTCCATTCATTCACGAAATTGGCGGGCAGGCGATGCTCTTGG
TCGCGGTGAAAAAATAGCAGATATCGAAAAGAATATGGGAATGGTTATTGAAGGAGTTTCAACGACTAAAGCAGCTTATG
AGCTTGCTCAACGCCTTGAAATTGACATGCCTATCACTGAAACAATTTACAAAGTTCTTTATGAAAATCTTGATGCAAAA
TCTGGAATTCTTGATATCATGCGCCGCGAAACTCGTGCTGAAAATGAATTCATTAATATTAATAAATAA

Upstream 100 bases:

>100_bases
TATCATAATATTTAAACCCTAAATCATACTTAGGGCTGATTTTTATTCTTGCTTATGTTAAAATGTAAAGGAAACCAAAA
CAAAAGAAAGGATCATTTCT

Downstream 100 bases:

>100_bases
AATAATAAATAAAAAAATTCGATTTTACTAATTAAATAAAGGAGTTAATTATCATGAAACAAACTACTATACCTAACAAA
GCCAGAAAAGTTCGTAAAGC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNLEQMAEINEKHTNTRYFKDVVLDEKIKAYSRLDLALENVDAILFV
VPTKVTRLVAKQVAQVLKHKVHILHASKGLEQGTHDRISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASND
HDEAKYAQSIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKIADIEKNMGMVIEGVSTTKAAYELAQRLEIDMPITETIYKVLYENLDAK
SGILDIMRRETRAENEFININK

Sequences:

>Translated_342_residues
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNLEQMAEINEKHTNTRYFKDVVLDEKIKAYSRLDLALENVDAILFV
VPTKVTRLVAKQVAQVLKHKVHILHASKGLEQGTHDRISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASND
HDEAKYAQSIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKIADIEKNMGMVIEGVSTTKAAYELAQRLEIDMPITETIYKVLYENLDAK
SGILDIMRRETRAENEFININK
>Mature_342_residues
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNLEQMAEINEKHTNTRYFKDVVLDEKIKAYSRLDLALENVDAILFV
VPTKVTRLVAKQVAQVLKHKVHILHASKGLEQGTHDRISTILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASND
HDEAKYAQSIFSNDYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKIADIEKNMGMVIEGVSTTKAAYELAQRLEIDMPITETIYKVLYENLDAK
SGILDIMRRETRAENEFININK

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=337, Percent_Identity=28.7833827893175, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI24307999, Length=338, Percent_Identity=28.9940828402367, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=40.1812688821752, Blast_Score=243, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI32564403, Length=357, Percent_Identity=26.3305322128852, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193210136, Length=357, Percent_Identity=26.3305322128852, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI32564399, Length=349, Percent_Identity=26.0744985673352, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17507425, Length=335, Percent_Identity=26.865671641791, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193210134, Length=348, Percent_Identity=24.7126436781609, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320181, Length=347, Percent_Identity=28.8184438040346, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324513, Length=345, Percent_Identity=27.2463768115942, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17136200, Length=347, Percent_Identity=29.971181556196, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136204, Length=347, Percent_Identity=30.2593659942363, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136202, Length=347, Percent_Identity=29.971181556196, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI22026922, Length=336, Percent_Identity=24.1071428571429, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45551945, Length=235, Percent_Identity=25.1063829787234, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281362270, Length=235, Percent_Identity=25.1063829787234, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648969, Length=187, Percent_Identity=25.668449197861, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_LACLM (A2RK98)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001032428.1
- ProteinModelPortal:   A2RK98
- SMR:   A2RK98
- STRING:   A2RK98
- GeneID:   4797670
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_1114
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 37350; Mature: 37350

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 194-194 BINDING 108-108 BINDING 108-108 BINDING 143-143 BINDING 258-258 BINDING 284-284

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNLEQMAEINEKHTNTRYFKDVVLDEK
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHH
IKAYSRLDLALENVDAILFVVPTKVTRLVAKQVAQVLKHKVHILHASKGLEQGTHDRIST
HHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASNDHDEAKYAQSIFSNDYFRLYT
HHHHHCCHHHCCCEEEEECCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEC
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKIADIEKNMGMVIEGVSTTKAAYELAQRLE
CCCCCCCEEEECCEEECCCCCCCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHC
IDMPITETIYKVLYENLDAKSGILDIMRRETRAENEFININK
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MNPQKIAVLGPGSWGTALSQVLNDNGHEVRIWGNNLEQMAEINEKHTNTRYFKDVVLDEK
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHH
IKAYSRLDLALENVDAILFVVPTKVTRLVAKQVAQVLKHKVHILHASKGLEQGTHDRIST
HHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
ILEEEIPAQLRGEIVVVSGPSHAEETIVRDITLISAASNDHDEAKYAQSIFSNDYFRLYT
HHHHHCCHHHCCCEEEEECCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIITRGLAEITRLGVAMGAEPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEC
GLSGVGDLIVTGTSIHSRNWRAGDALGRGEKIADIEKNMGMVIEGVSTTKAAYELAQRLE
CCCCCCCEEEECCEEECCCCCCCCCCCCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHHC
IDMPITETIYKVLYENLDAKSGILDIMRRETRAENEFININK
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA