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The map label for this gene is gpo [H]

Identifier: 125623919

GI number: 125623919

Start: 1046138

End: 1046611

Strand: Direct

Name: gpo [H]

Synonym: llmg_1088

Alternate gene names: 125623919

Gene position: 1046138-1046611 (Clockwise)

Preceding gene: 125623917

Following gene: 125623920

Centisome position: 41.36

GC content: 33.33

Gene sequence:

>474_bases
ATGAATTTTTATGATTTTAGTGCCGTTAAAATGAACGGTGAAACTGTTTCAATGTCTGACTACAAAGGAAAAGTCGTAAT
CGTAGTCAATACAGCCAGTAAATGTGGTTTTACTCCACAATTTGAGGGACTTGAAAAATTGTATGAAACATATAAAGACC
AAGGATTAGAGATTCTAGGATTTCCTTGTAATCAGTTTGCTAATCAAGATGCTGGTGAAAATACGGAAATTAATGAATTC
TGTCAGTTGAATTATGGGGTTACATTCACCATGTTTCAAAAAATTAAAGTAAATGGAAAAGAAGCTCATCCACTTTATCA
ATTTTTGAAAAAGGAAGCCAAAGGGGCGCTTAGTGGAACTATTAAATGGAATTTCACAAAGTTTTTAATTGACCGAGATG
GACAAGTCATTGAACGATTTGCTCCCAAAACGGAGCCTGAAGAAATGGAAGAAGAAATCAAAAAATTACTTTAA

Upstream 100 bases:

>100_bases
CAATCAATTTTTATGCTGAGCCATCTGTCAGTAAAAATAAATCTATAAATTATTTCTGATGGAATAACTTATATAGCAAA
ATTTACCAGGAGGTAAACAA

Downstream 100 bases:

>100_bases
AAGTCATAAATGGTCTGAGACTTGTAAAAGGTCAATTATTTTGCTAAACTAATAAACAATAAAACTTTTAATCTAGTCCA
GAGAGGCTAGCAAGGTTGTG

Product: gluthatione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNFYDFSAVKMNGETVSMSDYKGKVVIVVNTASKCGFTPQFEGLEKLYETYKDQGLEILGFPCNQFANQDAGENTEINEF
CQLNYGVTFTMFQKIKVNGKEAHPLYQFLKKEAKGALSGTIKWNFTKFLIDRDGQVIERFAPKTEPEEMEEEIKKLL

Sequences:

>Translated_157_residues
MNFYDFSAVKMNGETVSMSDYKGKVVIVVNTASKCGFTPQFEGLEKLYETYKDQGLEILGFPCNQFANQDAGENTEINEF
CQLNYGVTFTMFQKIKVNGKEAHPLYQFLKKEAKGALSGTIKWNFTKFLIDRDGQVIERFAPKTEPEEMEEEIKKLL
>Mature_157_residues
MNFYDFSAVKMNGETVSMSDYKGKVVIVVNTASKCGFTPQFEGLEKLYETYKDQGLEILGFPCNQFANQDAGENTEINEF
CQLNYGVTFTMFQKIKVNGKEAHPLYQFLKKEAKGALSGTIKWNFTKFLIDRDGQVIERFAPKTEPEEMEEEIKKLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=45.8064516129032, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=45.8064516129032, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI15618997, Length=157, Percent_Identity=39.4904458598726, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI192455698, Length=157, Percent_Identity=37.5796178343949, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=46.9230769230769, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=33.5260115606936, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=32.0441988950276, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=33.879781420765, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI6006001, Length=171, Percent_Identity=35.672514619883, Blast_Score=90, Evalue=7e-19,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=30.5084745762712, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788003, Length=158, Percent_Identity=43.0379746835443, Blast_Score=145, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17506887, Length=155, Percent_Identity=50.3225806451613, Blast_Score=163, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17535473, Length=146, Percent_Identity=48.6301369863014, Blast_Score=148, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71993584, Length=155, Percent_Identity=41.2903225806452, Blast_Score=139, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI193210707, Length=159, Percent_Identity=45.2830188679245, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=36.8098159509202, Blast_Score=109, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=33.7423312883436, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17507603, Length=105, Percent_Identity=37.1428571428571, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71999642, Length=74, Percent_Identity=39.1891891891892, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=45.8333333333333, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=34.0425531914894, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=51.5923566878981, Blast_Score=175, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322228, Length=156, Percent_Identity=51.9230769230769, Blast_Score=173, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322826, Length=157, Percent_Identity=49.0445859872611, Blast_Score=159, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24656772, Length=159, Percent_Identity=45.2830188679245, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=45.2830188679245, Blast_Score=136, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=45.2830188679245, Blast_Score=135, Evalue=8e-33,
Organism=Drosophila melanogaster, GI85726443, Length=147, Percent_Identity=39.4557823129252, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17970; Mature: 17970

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFYDFSAVKMNGETVSMSDYKGKVVIVVNTASKCGFTPQFEGLEKLYETYKDQGLEILG
CCCCCCEEEEECCCEEEECCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEEE
FPCNQFANQDAGENTEINEFCQLNYGVTFTMFQKIKVNGKEAHPLYQFLKKEAKGALSGT
CCCHHHCCCCCCCCCCHHHHEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCEECE
IKWNFTKFLIDRDGQVIERFAPKTEPEEMEEEIKKLL
EEECEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MNFYDFSAVKMNGETVSMSDYKGKVVIVVNTASKCGFTPQFEGLEKLYETYKDQGLEILG
CCCCCCEEEEECCCEEEECCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEEE
FPCNQFANQDAGENTEINEFCQLNYGVTFTMFQKIKVNGKEAHPLYQFLKKEAKGALSGT
CCCHHHCCCCCCCCCCHHHHEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCEECE
IKWNFTKFLIDRDGQVIERFAPKTEPEEMEEEIKKLL
EEECEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]