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The map label for this gene is purQ

Identifier: 125623814

GI number: 125623814

Start: 937905

End: 938585

Strand: Direct

Name: purQ

Synonym: llmg_0975

Alternate gene names: 125623814

Gene position: 937905-938585 (Clockwise)

Preceding gene: 125623813

Following gene: 125623815

Centisome position: 37.08

GC content: 38.47

Gene sequence:

>681_bases
ATGAAATTTGCAGTCATTCAATTTCCAGGGTCAAATTGCGATTTTGATTTACTTTGGGCAATTCGTGATGTCATGGGGGC
AGAGGCAGAATTTGTCTGGCATGACGAGAAGTCACTTGCAGGATTTGATGGAGTATTGATTCCTGGTGGATTTTCTTATG
GCGATTATTTGCGCTGTGGTGCGATTGCTTCATTTGCTAACATTATGCCTGAAATCAAACGTTTGGCTAAAGAAGGGAAG
CCTGTTTTTGGCACTTGTAATGGATTTCAAATTTTGGTTGAATCTGGGCTTTTACCAGGTGTATTGATTCGCAATGAGGG
TTTGAAATTTGTTTCCAAATGGCAAGTCCTTAAAGTTGAAAATAATCAAAGTAATTTTACGACTGAATATGCTAAAGATG
CCTTGATTAATTTACCCATCGCCCACGGCGAAGGCCAATATGTTGCTGACGAAGCAACGCTTGCTGAACTTAAAGAAAAT
GGTCAAATCGTTTTCACTTATGCAGATGAAAATCCTAATGGTTCAGTTGAAAATATTGCTGGAATTATCAATAAAGAAGG
AAATGTACTTGGGATGATGCCTCATCCTGAGCGTGCTATGGAAGAATTGCTTGGTGGAGCTGACGGAAGAAAAATGTTTG
CCTCTTTGTTGAAAAATTTTCTAGTGACTGTAAAAAATTAA

Upstream 100 bases:

>100_bases
AAGAAAAAGCGACTGAAATTGCCAATGAATTGTTGGCGAATCCAAATATGGAAACTTACAAAGTTGAAATTTTGACTGAA
CAAAGTGAAGGAGTCAAAAA

Downstream 100 bases:

>100_bases
GAAAAATTTGCTGACAGCTTTGTCAGTAAGCTGAAAACTTGTAAAATTTGCTGACAGAACTGTCAGTGAGTTTGTAATTT
GAAATTAACTGAGTTCGCCC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCGAIASFANIMPEIKRLAKEGK
PVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQVLKVENNQSNFTTEYAKDALINLPIAHGEGQYVADEATLAELKEN
GQIVFTYADENPNGSVENIAGIINKEGNVLGMMPHPERAMEELLGGADGRKMFASLLKNFLVTVKN

Sequences:

>Translated_226_residues
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCGAIASFANIMPEIKRLAKEGK
PVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQVLKVENNQSNFTTEYAKDALINLPIAHGEGQYVADEATLAELKEN
GQIVFTYADENPNGSVENIAGIINKEGNVLGMMPHPERAMEELLGGADGRKMFASLLKNFLVTVKN
>Mature_226_residues
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCGAIASFANIMPEIKRLAKEGK
PVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQVLKVENNQSNFTTEYAKDALINLPIAHGEGQYVADEATLAELKEN
GQIVFTYADENPNGSVENIAGIINKEGNVLGMMPHPERAMEELLGGADGRKMFASLLKNFLVTVKN

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=226, Percent_Identity=28.3185840707965, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=231, Percent_Identity=26.4069264069264, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582111, Length=237, Percent_Identity=29.535864978903, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24582109, Length=237, Percent_Identity=29.535864978903, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17137292, Length=237, Percent_Identity=29.535864978903, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_LACLC (Q9ZB07)

Other databases:

- EMBL:   U64311
- PIR:   T51700
- ProteinModelPortal:   Q9ZB07
- SMR:   Q9ZB07
- BRENDA:   6.3.5.3
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF00117 GATase

EC number: =6.3.5.3

Molecular weight: Translated: 24738; Mature: 24738

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 86-86 ACT_SITE 195-195 ACT_SITE 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHH
AIASFANIMPEIKRLAKEGKPVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQVLKVE
HHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCEEEECCCCCEEEEEEEEEEE
NNQSNFTTEYAKDALINLPIAHGEGQYVADEATLAELKENGQIVFTYADENPNGSVENIA
CCCCCCHHHHHHHHEEECEEECCCCCEEECHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
GIINKEGNVLGMMPHPERAMEELLGGADGRKMFASLLKNFLVTVKN
HHCCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKFAVIQFPGSNCDFDLLWAIRDVMGAEAEFVWHDEKSLAGFDGVLIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCCCCCCHHHHH
AIASFANIMPEIKRLAKEGKPVFGTCNGFQILVESGLLPGVLIRNEGLKFVSKWQVLKVE
HHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCEEEECCCCCEEEEEEEEEEE
NNQSNFTTEYAKDALINLPIAHGEGQYVADEATLAELKENGQIVFTYADENPNGSVENIA
CCCCCCHHHHHHHHEEECEEECCCCCEEECHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
GIINKEGNVLGMMPHPERAMEELLGGADGRKMFASLLKNFLVTVKN
HHCCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10071207