Click here to switch to the map view.

The map label for this gene is dapB [H]

Identifier: 125623781

GI number: 125623781

Start: 908026

End: 908808

Strand: Direct

Name: dapB [H]

Synonym: llmg_0940

Alternate gene names: 125623781

Gene position: 908026-908808 (Clockwise)

Preceding gene: 125623780

Following gene: 125623782

Centisome position: 35.9

GC content: 41.51

Gene sequence:

>783_bases
ATGATTTTGAATAAAATTAAAGTGGTTGTGGCAGGATTTCGTGGAAAAATGGGTTCGACGGCTGTGCAAATGATTCTCAA
CGCTCCTAATTTTGAACTTGTCGCTTTATTAGGGAGAAAAGAAGAAGTTTCTGAGGCCTTTGATGTTCCTGTATTCAATC
GAAAAGAGGAGCTAGAGAATATTGAAGCAGACGTTTGGTTGGATTTGACAGCTCCAGAGGTTGCTTATGAGAATACTTAT
TTTGCGCTGGAACATGGCTTAAGACCTGTTGTGGGCACAACTGGATTTACTGAGGATGAAGTGGCTCGTTTAATAAAATT
TTCTAGGGAGAAAGAACTGGGTGGACTAATTGCACCTAATTTTGCCTTAGGTGCGGTTTTATTAATGCAATTCTCGAAAC
AGGCCGTGAAATATTTCCCAGATGTAGAAATTATTGAGTTACATCATGATGGTAAAAAGGATGCGCCTTCTGGAACTGCT
GTAAAAACGGCAGAATTGATGGCTGAGGAACGTCTGGCTCATCATCAAGGGGCAGTAGATGAAAAAGAATCATTAGTTGG
GGCGCGGGGAGCTGTTCTTGAGGGGATGAGGATTCATTCAGTTCGCTTACCAGGTCTGGTGGCTCATCAAGAAGTCATTT
TTGGCTCAAAAGGTGAAGGATTGACCTTGCGCCATGACTCTTACGACCGTTCAAGCTTTATGACTGGAATTGCACTTGGA
ATTCGTAAAGTGATGACCGTTTCTGAGCTAAAATATGGCTTAGAACACTTTTTAGACTTATAA

Upstream 100 bases:

>100_bases
AGAAATATTCTGAATAATAGAAATAATAGCGGTTACTAACAAATACTGATTTATTTACTTAGTTAATTCTTTTATTATAA
TAAAATGTTTGAGTGAGGAT

Downstream 100 bases:

>100_bases
TTTTTTTGACGATAGAGTAAGTTTGCAAGAGCTTTTCTATAATAAAACCTTTAGTGGGGTGCTTTATGAGTAATTTGGAA
ATTCGTAGATTAGACTTAAG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MILNKIKVVVAGFRGKMGSTAVQMILNAPNFELVALLGRKEEVSEAFDVPVFNRKEELENIEADVWLDLTAPEVAYENTY
FALEHGLRPVVGTTGFTEDEVARLIKFSREKELGGLIAPNFALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTA
VKTAELMAEERLAHHQGAVDEKESLVGARGAVLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
IRKVMTVSELKYGLEHFLDL

Sequences:

>Translated_260_residues
MILNKIKVVVAGFRGKMGSTAVQMILNAPNFELVALLGRKEEVSEAFDVPVFNRKEELENIEADVWLDLTAPEVAYENTY
FALEHGLRPVVGTTGFTEDEVARLIKFSREKELGGLIAPNFALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTA
VKTAELMAEERLAHHQGAVDEKESLVGARGAVLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
IRKVMTVSELKYGLEHFLDL
>Mature_260_residues
MILNKIKVVVAGFRGKMGSTAVQMILNAPNFELVALLGRKEEVSEAFDVPVFNRKEELENIEADVWLDLTAPEVAYENTY
FALEHGLRPVVGTTGFTEDEVARLIKFSREKELGGLIAPNFALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTA
VKTAELMAEERLAHHQGAVDEKESLVGARGAVLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
IRKVMTVSELKYGLEHFLDL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=272, Percent_Identity=29.0441176470588, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28673; Mature: 28673

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILNKIKVVVAGFRGKMGSTAVQMILNAPNFELVALLGRKEEVSEAFDVPVFNRKEELEN
CCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCCCCCHHHHHC
IEADVWLDLTAPEVAYENTYFALEHGLRPVVGTTGFTEDEVARLIKFSREKELGGLIAPN
CCCEEEEECCCCCHHHCCCEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCH
FALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTAVKTAELMAEERLAHHQGAVD
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EKESLVGARGAVLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
HHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHH
IRKVMTVSELKYGLEHFLDL
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILNKIKVVVAGFRGKMGSTAVQMILNAPNFELVALLGRKEEVSEAFDVPVFNRKEELEN
CCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHCCCCCCCHHHHHC
IEADVWLDLTAPEVAYENTYFALEHGLRPVVGTTGFTEDEVARLIKFSREKELGGLIAPN
CCCEEEEECCCCCHHHCCCEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEECCH
FALGAVLLMQFSKQAVKYFPDVEIIELHHDGKKDAPSGTAVKTAELMAEERLAHHQGAVD
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EKESLVGARGAVLEGMRIHSVRLPGLVAHQEVIFGSKGEGLTLRHDSYDRSSFMTGIALG
HHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHH
IRKVMTVSELKYGLEHFLDL
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA