Click here to switch to the map view.

The map label for this gene is arsC [H]

Identifier: 125623745

GI number: 125623745

Start: 869928

End: 870332

Strand: Direct

Name: arsC [H]

Synonym: llmg_0902

Alternate gene names: 125623745

Gene position: 869928-870332 (Clockwise)

Preceding gene: 125623744

Following gene: 125623746

Centisome position: 34.39

GC content: 35.56

Gene sequence:

>405_bases
ATGAAAAAAATTTATTTTCTTTGTACGGGTAATTCTTGTCGTTCTCAAATAGCGGAAGGATATGGGCATGTATTTTTAAA
GGATTGGGAAGTCCGTTCCGCAGGAATAGAAAGACACGGTTTAAATCCACATGCGGTAACAGTAATGGCAGAAGATGGCA
TTGATATTTCGGCTCAAAAATCAGAATTAATTGATATGACTTATTTTAATGACTGTGATTTAATTATTACTTTATGCGGT
GATGCTCTTGATAAGTGTCCAATGATTCCTAAATCAGTGAGCCATGAACATTGGGACTTACAAGATCCAGCTCGGGCTGT
TGGAACAGAGGCAGACATTTTAACAGAATTTAGAAAAACCAGAGATTTGATAAAAGAACGAGTCCAAAACTTAAGCAATA
TATAA

Upstream 100 bases:

>100_bases
CCAAAAGGCATACAAGATTTTTACATTTTAGAGGGAATTAAAAATAAAAATATGCCTCAAATATTATATAATGAAATAAT
AAAAAAAATGAGATTTGTTG

Downstream 100 bases:

>100_bases
ATCTATCCAATGAGTTTTAGACCAATTTCCTTTTATGTATAAAAATGACGTCTTTAAGGCGTTTTTTAGTTTGAAATTTA
TAAAATAGACAATATGATAT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MKKIYFLCTGNSCRSQIAEGYGHVFLKDWEVRSAGIERHGLNPHAVTVMAEDGIDISAQKSELIDMTYFNDCDLIITLCG
DALDKCPMIPKSVSHEHWDLQDPARAVGTEADILTEFRKTRDLIKERVQNLSNI

Sequences:

>Translated_134_residues
MKKIYFLCTGNSCRSQIAEGYGHVFLKDWEVRSAGIERHGLNPHAVTVMAEDGIDISAQKSELIDMTYFNDCDLIITLCG
DALDKCPMIPKSVSHEHWDLQDPARAVGTEADILTEFRKTRDLIKERVQNLSNI
>Mature_134_residues
MKKIYFLCTGNSCRSQIAEGYGHVFLKDWEVRSAGIERHGLNPHAVTVMAEDGIDISAQKSELIDMTYFNDCDLIITLCG
DALDKCPMIPKSVSHEHWDLQDPARAVGTEADILTEFRKTRDLIKERVQNLSNI

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15125; Mature: 15125

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIYFLCTGNSCRSQIAEGYGHVFLKDWEVRSAGIERHGLNPHAVTVMAEDGIDISAQK
CCEEEEEEECCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
SELIDMTYFNDCDLIITLCGDALDKCPMIPKSVSHEHWDLQDPARAVGTEADILTEFRKT
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
RDLIKERVQNLSNI
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIYFLCTGNSCRSQIAEGYGHVFLKDWEVRSAGIERHGLNPHAVTVMAEDGIDISAQK
CCEEEEEEECCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
SELIDMTYFNDCDLIITLCGDALDKCPMIPKSVSHEHWDLQDPARAVGTEADILTEFRKT
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
RDLIKERVQNLSNI
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]