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The map label for this gene is asd [H]

Identifier: 125623715

GI number: 125623715

Start: 841072

End: 842157

Strand: Direct

Name: asd [H]

Synonym: llmg_0871

Alternate gene names: 125623715

Gene position: 841072-842157 (Clockwise)

Preceding gene: 125623714

Following gene: 125623716

Centisome position: 33.25

GC content: 39.5

Gene sequence:

>1086_bases
ATGACACAATATAATATCGCGGTCGTTGGGGCTACTGGTGCCGTAGGAACAAGAATGCTTGAGCAATTAGAAAAATCTAC
TCTTCCAATAGAAACCGTACGTGCACTTGCCAGTAAACGTTCGGCGGGTAAAATTGTAGAGTTCAAAGGTCAAGAGCTTG
TCATAGAAGAGTTGACTGAGGACAGTTTTGAAGGCATTGATATCGCACTGTTTTCAGCTGGAGGTTCGGTTTCTGAAAAA
TTTGCCCCTTATGCTGTAAAAGCTGGAGCGGTAGTTGTGGATAATACATCGTTTTTCCGTCAAAATCCTAATGTTCCTTT
GGTTGTTCCAGAAGTTAATGCACATGCACTTGAACAACATAATGGAATTATTGCTTGTCCCAATTGTTCAACAATTCAAA
TGATGATTGCTTTAGAGCCAATTCGTCGTGCTTATGGCCTTGAACGTGTGATTGTCAGTACTTATCAAGCAGTATCTGGT
GCTGGTCAGTCCGCAATTAATGAAACTAATCGTGAACTTCAAGAAGCTCTTGATGGAAAAGCACTGACAGAATTGTCAGC
AGAAATTTTACCATCTGCTGGTGATAAAAAGCATTATCCGATTGCTTATAATGCCCTTGCACAAATTGATGTTTTTACTG
ACAATGATTATACTTATGAAGAAATGAAAATGACAAATGAAACCAAGAAAATCATGGAAGATGATTCAATTGCGGTTTCT
GCAACTTGTGTCAGAATTCCAGTTCTCTATGGTCATTCTGAATCAGTTTATGTTGAAACGAAAAAAGAAGCAGATATTGC
TGAGGTCAAGCGTCTAATTTCTGAGTTCCCAGGGGCGGTCTTGGAAGATGATGTCGCACATCAAATTTATCCACAAGCCA
TTAATTCAGTTGGTCGTCGTGAAACTTTTGTGGGCCGTATTCGTCGTGATTTGGATGCAGCCAATGGGATTCATCTTTGG
GTAGTTTCTGACAATTTACTCAAAGGAGCTGCTTGGAATTCTGTCCAAATTGCCGAAACGTTGCATGAACGTGGCTTGGT
TAGACCAACTAAAGAATTAAAATTTGAATTGAAAGAAGGTATTTAA

Upstream 100 bases:

>100_bases
AATAAAATGAAAAAAATCTGTCTGATAGGCAGATTTTTTCTTGCCCTTAGAACTTAAAAGCGCTATAATGATTATAATTT
ACTGAAAAGGACAGACAATT

Downstream 100 bases:

>100_bases
ATGAGCTATGTCAGTGATATCCGTAAGAAAATAGGGAACGACTTGTTAATGGGGATTGGCAGTGGAGTTATCATTGAACA
AGATGGTAAGATTCTTCTGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTQYNIAVVGATGAVGTRMLEQLEKSTLPIETVRALASKRSAGKIVEFKGQELVIEELTEDSFEGIDIALFSAGGSVSEK
FAPYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEQHNGIIACPNCSTIQMMIALEPIRRAYGLERVIVSTYQAVSG
AGQSAINETNRELQEALDGKALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVS
ATCVRIPVLYGHSESVYVETKKEADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRRETFVGRIRRDLDAANGIHLW
VVSDNLLKGAAWNSVQIAETLHERGLVRPTKELKFELKEGI

Sequences:

>Translated_361_residues
MTQYNIAVVGATGAVGTRMLEQLEKSTLPIETVRALASKRSAGKIVEFKGQELVIEELTEDSFEGIDIALFSAGGSVSEK
FAPYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEQHNGIIACPNCSTIQMMIALEPIRRAYGLERVIVSTYQAVSG
AGQSAINETNRELQEALDGKALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVS
ATCVRIPVLYGHSESVYVETKKEADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRRETFVGRIRRDLDAANGIHLW
VVSDNLLKGAAWNSVQIAETLHERGLVRPTKELKFELKEGI
>Mature_360_residues
TQYNIAVVGATGAVGTRMLEQLEKSTLPIETVRALASKRSAGKIVEFKGQELVIEELTEDSFEGIDIALFSAGGSVSEKF
APYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEQHNGIIACPNCSTIQMMIALEPIRRAYGLERVIVSTYQAVSGA
GQSAINETNRELQEALDGKALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVSA
TCVRIPVLYGHSESVYVETKKEADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRRETFVGRIRRDLDAANGIHLWV
VSDNLLKGAAWNSVQIAETLHERGLVRPTKELKFELKEGI

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=341, Percent_Identity=30.2052785923754, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1789841, Length=358, Percent_Identity=25.4189944134078, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320362, Length=403, Percent_Identity=27.0471464019851, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39567; Mature: 39436

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYNIAVVGATGAVGTRMLEQLEKSTLPIETVRALASKRSAGKIVEFKGQELVIEELTE
CCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHCC
DSFEGIDIALFSAGGSVSEKFAPYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEQH
CCCCCEEEEEEECCCCCCCCCCCEEEECCEEEEECCHHHHCCCCCCEEEECCCHHHHHHC
NGIIACPNCSTIQMMIALEPIRRAYGLERVIVSTYQAVSGAGQSAINETNRELQEALDGK
CCEEECCCCCCEEHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCH
ALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVS
HHHHHHHHHCCCCCCCCCCCEEEECEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEE
ATCVRIPVLYGHSESVYVETKKEADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRR
EEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCHHCHHHHHHHHHHHHHHHHHH
ETFVGRIRRDLDAANGIHLWVVSDNLLKGAAWNSVQIAETLHERGLVRPTKELKFELKEG
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCC
I
C
>Mature Secondary Structure 
TQYNIAVVGATGAVGTRMLEQLEKSTLPIETVRALASKRSAGKIVEFKGQELVIEELTE
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHCC
DSFEGIDIALFSAGGSVSEKFAPYAVKAGAVVVDNTSFFRQNPNVPLVVPEVNAHALEQH
CCCCCEEEEEEECCCCCCCCCCCEEEECCEEEEECCHHHHCCCCCCEEEECCCHHHHHHC
NGIIACPNCSTIQMMIALEPIRRAYGLERVIVSTYQAVSGAGQSAINETNRELQEALDGK
CCEEECCCCCCEEHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCH
ALTELSAEILPSAGDKKHYPIAYNALAQIDVFTDNDYTYEEMKMTNETKKIMEDDSIAVS
HHHHHHHHHCCCCCCCCCCCEEEECEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEE
ATCVRIPVLYGHSESVYVETKKEADIAEVKRLISEFPGAVLEDDVAHQIYPQAINSVGRR
EEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCHHCHHHHHHHHHHHHHHHHHH
ETFVGRIRRDLDAANGIHLWVVSDNLLKGAAWNSVQIAETLHERGLVRPTKELKFELKEG
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2434499; 12397186 [H]