Click here to switch to the map view.

The map label for this gene is uxaC [H]

Identifier: 125623707

GI number: 125623707

Start: 830323

End: 831741

Strand: Direct

Name: uxaC [H]

Synonym: llmg_0862

Alternate gene names: 125623707

Gene position: 830323-831741 (Clockwise)

Preceding gene: 125623706

Following gene: 125623708

Centisome position: 32.83

GC content: 35.1

Gene sequence:

>1419_bases
ATGAAATTTTTATCAGAAGATTTTTTACTAAATAATGAAAGTGCTAAGTTACTCTTTCATGAACATGCGGAAAAAATGCC
AATTATTGATTATCATTGCCATCTTGAACCAGCAGAAATTTATGAAAACAAAAAATATGAAAATTTAACTCAAATCTGGC
TAGGTGGAGACCATTATAAATGGCGGTTACTTCGCGCGAATGGCATTCCTGAAAAATTGATTACTGGCGATGGTGATGAC
TACGAAAAGTTTTTAGCCTTTGCTAAAACACTTGAAAAATCATTAGGAAATCCAATTTATGAATGGACACATCTGGAGTT
AAAACGATTTTTCCATATTGATAAGTTGATTTCAAGCGAAACAGAAAAAGAAATTTGGGACGAAGCCAACCAAATGCTCG
CAACAGATGATTTCAGACCACGCGCATTGATTAAAAATTCAAATGTCAAAGTCGTCTGTACAACAGATGACCCTGTTTCA
AAGCTTTCTTATCATAAATCATTAGCCAAAGAAGAAAAAGATTTTAAGGTTTTGCCAGCATTAAGGCCTGACCATTTAAT
TTCCATTACTGACGGACATTTTGCAGAATATCTGATGGAACTGTCAGCAGTTTCTGGAATAAAAATCAAGGACTTTAAGA
CAATGATTAAGGCACTTGAACAAAGATTTGAATTTTTCACAAGCCTCGGTGGACGTTTGTCTGACCACTCTCTTTCCACT
TATACTTTTGCAGAAACTAAAAACGTGGATTTAGATTCTATCCTTCAGAAAGCTAAAGAAAATCAAACTTTAACAGACCT
AGAATACAATCAATACATTACAGCATTAATCCTTGAAATTATGAAATTAAATAAAAAATTTGACTGGACAATGCAACTTC
ATGTCAATGTTAACCGCTCAATCAATGGTCCTGCTCTTCGGAAAATTGGCGAAAATACTGGATTTGATAGTATGGGGACC
CAAGCTAACATTTCAGAAGAACTAACCAAACTATTTAGCAAAGCAGCAGAACTTGAAATTATACCAAAAACGATACTCTA
TTCACTTAATCAAAATGATTGGCTTGAATTAGCGACACTGATTGGCTGTTTCCAAGGTGAAGGCGTTCAACAATTGCAAC
TGGGAGCTGGTTGGTGGTTCAATGATACAGCCAAAGGAATGGAAAAACAACTCGAAATTTTTGCTTCACAAAGCTTACTG
CCCAATTTTGTCGGAATGTTGACAGATTCACGGAGCTTTTTAAGTTATCCACGTCATGAATACTTCCGTCGTGTCCTTTG
TAATTTTGTTGGACAATTGATTGAAAGTGGCAGAATTCCCGATGATGAAGCACTTGTCGGAAAAATGATTGAAGATATAA
GTTATAACAATGTTCATGACTACTTTGGCTTCTTTAAAAATGAGGATTCTAAGCAATGA

Upstream 100 bases:

>100_bases
AGAACTCTTGCAAAAAGAAGGAAATATCAGCTTAAAAGCAAATGAGTCTAAAACTTACGAAGTTGAATTAAATTTTAATA
GAAAATAATAAAGGAGAATC

Downstream 100 bases:

>100_bases
GCGAATTTATAACCATTGGTGAACCCTTAGTCGTTCTCGCCTCAGAAAATCAAGATATAAGCTTAGAAGCAGCGGAGCGT
TTTAGCAAATATTTAGCAGG

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKFLSEDFLLNNESAKLLFHEHAEKMPIIDYHCHLEPAEIYENKKYENLTQIWLGGDHYKWRLLRANGIPEKLITGDGDD
YEKFLAFAKTLEKSLGNPIYEWTHLELKRFFHIDKLISSETEKEIWDEANQMLATDDFRPRALIKNSNVKVVCTTDDPVS
KLSYHKSLAKEEKDFKVLPALRPDHLISITDGHFAEYLMELSAVSGIKIKDFKTMIKALEQRFEFFTSLGGRLSDHSLST
YTFAETKNVDLDSILQKAKENQTLTDLEYNQYITALILEIMKLNKKFDWTMQLHVNVNRSINGPALRKIGENTGFDSMGT
QANISEELTKLFSKAAELEIIPKTILYSLNQNDWLELATLIGCFQGEGVQQLQLGAGWWFNDTAKGMEKQLEIFASQSLL
PNFVGMLTDSRSFLSYPRHEYFRRVLCNFVGQLIESGRIPDDEALVGKMIEDISYNNVHDYFGFFKNEDSKQ

Sequences:

>Translated_472_residues
MKFLSEDFLLNNESAKLLFHEHAEKMPIIDYHCHLEPAEIYENKKYENLTQIWLGGDHYKWRLLRANGIPEKLITGDGDD
YEKFLAFAKTLEKSLGNPIYEWTHLELKRFFHIDKLISSETEKEIWDEANQMLATDDFRPRALIKNSNVKVVCTTDDPVS
KLSYHKSLAKEEKDFKVLPALRPDHLISITDGHFAEYLMELSAVSGIKIKDFKTMIKALEQRFEFFTSLGGRLSDHSLST
YTFAETKNVDLDSILQKAKENQTLTDLEYNQYITALILEIMKLNKKFDWTMQLHVNVNRSINGPALRKIGENTGFDSMGT
QANISEELTKLFSKAAELEIIPKTILYSLNQNDWLELATLIGCFQGEGVQQLQLGAGWWFNDTAKGMEKQLEIFASQSLL
PNFVGMLTDSRSFLSYPRHEYFRRVLCNFVGQLIESGRIPDDEALVGKMIEDISYNNVHDYFGFFKNEDSKQ
>Mature_472_residues
MKFLSEDFLLNNESAKLLFHEHAEKMPIIDYHCHLEPAEIYENKKYENLTQIWLGGDHYKWRLLRANGIPEKLITGDGDD
YEKFLAFAKTLEKSLGNPIYEWTHLELKRFFHIDKLISSETEKEIWDEANQMLATDDFRPRALIKNSNVKVVCTTDDPVS
KLSYHKSLAKEEKDFKVLPALRPDHLISITDGHFAEYLMELSAVSGIKIKDFKTMIKALEQRFEFFTSLGGRLSDHSLST
YTFAETKNVDLDSILQKAKENQTLTDLEYNQYITALILEIMKLNKKFDWTMQLHVNVNRSINGPALRKIGENTGFDSMGT
QANISEELTKLFSKAAELEIIPKTILYSLNQNDWLELATLIGCFQGEGVQQLQLGAGWWFNDTAKGMEKQLEIFASQSLL
PNFVGMLTDSRSFLSYPRHEYFRRVLCNFVGQLIESGRIPDDEALVGKMIEDISYNNVHDYFGFFKNEDSKQ

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=464, Percent_Identity=46.3362068965517, Blast_Score=444, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 54484; Mature: 54484

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLSEDFLLNNESAKLLFHEHAEKMPIIDYHCHLEPAEIYENKKYENLTQIWLGGDHYK
CCCCCCHHEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCHHHEEECCCCEE
WRLLRANGIPEKLITGDGDDYEKFLAFAKTLEKSLGNPIYEWTHLELKRFFHIDKLISSE
EEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCH
TEKEIWDEANQMLATDDFRPRALIKNSNVKVVCTTDDPVSKLSYHKSLAKEEKDFKVLPA
HHHHHHHHHHHEEECCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCCEECCC
LRPDHLISITDGHFAEYLMELSAVSGIKIKDFKTMIKALEQRFEFFTSLGGRLSDHSLST
CCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
YTFAETKNVDLDSILQKAKENQTLTDLEYNQYITALILEIMKLNKKFDWTMQLHVNVNRS
EEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCC
INGPALRKIGENTGFDSMGTQANISEELTKLFSKAAELEIIPKTILYSLNQNDWLELATL
CCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECHHHHHHCCCCHHHHHHHH
IGCFQGEGVQQLQLGAGWWFNDTAKGMEKQLEIFASQSLLPNFVGMLTDSRSFLSYPRHE
HHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
YFRRVLCNFVGQLIESGRIPDDEALVGKMIEDISYNNVHDYFGFFKNEDSKQ
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKFLSEDFLLNNESAKLLFHEHAEKMPIIDYHCHLEPAEIYENKKYENLTQIWLGGDHYK
CCCCCCHHEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCHHHEEECCCCEE
WRLLRANGIPEKLITGDGDDYEKFLAFAKTLEKSLGNPIYEWTHLELKRFFHIDKLISSE
EEEEECCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCH
TEKEIWDEANQMLATDDFRPRALIKNSNVKVVCTTDDPVSKLSYHKSLAKEEKDFKVLPA
HHHHHHHHHHHEEECCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCCEECCC
LRPDHLISITDGHFAEYLMELSAVSGIKIKDFKTMIKALEQRFEFFTSLGGRLSDHSLST
CCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
YTFAETKNVDLDSILQKAKENQTLTDLEYNQYITALILEIMKLNKKFDWTMQLHVNVNRS
EEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCC
INGPALRKIGENTGFDSMGTQANISEELTKLFSKAAELEIIPKTILYSLNQNDWLELATL
CCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECHHHHHHCCCCHHHHHHHH
IGCFQGEGVQQLQLGAGWWFNDTAKGMEKQLEIFASQSLLPNFVGMLTDSRSFLSYPRHE
HHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
YFRRVLCNFVGQLIESGRIPDDEALVGKMIEDISYNNVHDYFGFFKNEDSKQ
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]