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The map label for this gene is rbsK [H]

Identifier: 125623636

GI number: 125623636

Start: 774091

End: 775011

Strand: Direct

Name: rbsK [H]

Synonym: llmg_0785

Alternate gene names: 125623636

Gene position: 774091-775011 (Clockwise)

Preceding gene: 125623635

Following gene: 125623637

Centisome position: 30.6

GC content: 36.92

Gene sequence:

>921_bases
ATGACAAAAGTAAGTGTTGTAGGAAGTATTTCCATGGATTTAGTGACAAGCACAAAAAGAGTTCCACAAGCAGGTGAAAC
AGTTTTTGGAGAAAATTTTGCGATGGTTCCTGGTGGCAAGGGAGCAAATCAAGCCGTTGCTTTTGCTAGATTAGCTCCTC
GTGATGTAAATATGATTGGAGCAGTTGGAAATGATGCTTTTGGAGAAACTATTCTAAAAAACTTCAAAGAAAATGCTGTT
CTTTTTGACGATGTGGGAACGGTACCACAAACGACAGGGATTGCCCAAATTACCTTATTTGATGACGATAATCGAATTAT
CATTATTCCTGGGGCCAATAATGAAGTCCTTCCTGATTATTTAGAGAATTTCTGGGAGAAAATTAAAGACAGTCAACTTG
TGGTCTTACAAAATGAAATACCACATGAAACTAACCTTGCAGTTGCTAAATTTTGTAAAGAAAATGCGATAAAAGTCCTT
TATAATCCAGCTCCAGCAAGAAAAACGGATTTAGAAATGATTGAATTTGTAGATTACATCACGCCCAATGAACACGAATG
TAAGGAGCTTTTTCCGAATGAGTTTCTGGAGGAAATTCTTGCTAAATATGCGAATCGCCTGATTGTCACTTTAGGAAGTG
AAGGAGTGATTTTCCATGATGGTAATGAGGTTCAAAAAATTCCAGCAATTAAAGCTAAAGTGGTAGATACGACGGGAGCA
GGGGATACATTCAATGGAGCTTTTGCTTTTGGACTGACCGAAAATCTATCAATCGCTGATTCTATCCAATTGGCAGTGGT
TGCTTCCCATTTATCTATTCATAAATTTGGTGCTCAAGGTGGAATTCCAAGTCTAGCAGAAGTTGAAGATAAATTAAAAG
AGCTTAATCTTAATTTTTATAAGGAAAAGAAAGGACTTTGA

Upstream 100 bases:

>100_bases
GCAACTGATCAGCCTATTGAGAAATCAAAGATTGAGCTACCTGTTCATTATGTAGCGCGTGAAACAATTCGACAAAAAGG
AAAAGAATGAGGAAAAATTA

Downstream 100 bases:

>100_bases
ATTTATGAAAAAAGAAGGAATATTGAATAGTGAGCTTGCAAAAATCGCTGATGATTTGGGGCATACTGACCAAGTTTGTA
TTGGAGATTTAGGCTTACCG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTKVSVVGSISMDLVTSTKRVPQAGETVFGENFAMVPGGKGANQAVAFARLAPRDVNMIGAVGNDAFGETILKNFKENAV
LFDDVGTVPQTTGIAQITLFDDDNRIIIIPGANNEVLPDYLENFWEKIKDSQLVVLQNEIPHETNLAVAKFCKENAIKVL
YNPAPARKTDLEMIEFVDYITPNEHECKELFPNEFLEEILAKYANRLIVTLGSEGVIFHDGNEVQKIPAIKAKVVDTTGA
GDTFNGAFAFGLTENLSIADSIQLAVVASHLSIHKFGAQGGIPSLAEVEDKLKELNLNFYKEKKGL

Sequences:

>Translated_306_residues
MTKVSVVGSISMDLVTSTKRVPQAGETVFGENFAMVPGGKGANQAVAFARLAPRDVNMIGAVGNDAFGETILKNFKENAV
LFDDVGTVPQTTGIAQITLFDDDNRIIIIPGANNEVLPDYLENFWEKIKDSQLVVLQNEIPHETNLAVAKFCKENAIKVL
YNPAPARKTDLEMIEFVDYITPNEHECKELFPNEFLEEILAKYANRLIVTLGSEGVIFHDGNEVQKIPAIKAKVVDTTGA
GDTFNGAFAFGLTENLSIADSIQLAVVASHLSIHKFGAQGGIPSLAEVEDKLKELNLNFYKEKKGL
>Mature_305_residues
TKVSVVGSISMDLVTSTKRVPQAGETVFGENFAMVPGGKGANQAVAFARLAPRDVNMIGAVGNDAFGETILKNFKENAVL
FDDVGTVPQTTGIAQITLFDDDNRIIIIPGANNEVLPDYLENFWEKIKDSQLVVLQNEIPHETNLAVAKFCKENAIKVLY
NPAPARKTDLEMIEFVDYITPNEHECKELFPNEFLEEILAKYANRLIVTLGSEGVIFHDGNEVQKIPAIKAKVVDTTGAG
DTFNGAFAFGLTENLSIADSIQLAVVASHLSIHKFGAQGGIPSLAEVEDKLKELNLNFYKEKKGL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=292, Percent_Identity=34.5890410958904, Blast_Score=134, Evalue=9e-32,
Organism=Escherichia coli, GI1790193, Length=295, Percent_Identity=34.5762711864407, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI87082343, Length=288, Percent_Identity=27.4305555555556, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87081971, Length=283, Percent_Identity=24.3816254416961, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788491, Length=287, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=307, Percent_Identity=35.1791530944625, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=35.1515151515151, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=32.6732673267327, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24583886, Length=303, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33356; Mature: 33225

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVSVVGSISMDLVTSTKRVPQAGETVFGENFAMVPGGKGANQAVAFARLAPRDVNMIG
CCEEEEEECCHHHHHHHHHCCCCCCCEEECCCEEECCCCCCCCHHHHHHHCCCCCCEEEE
AVGNDAFGETILKNFKENAVLFDDVGTVPQTTGIAQITLFDDDNRIIIIPGANNEVLPDY
ECCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCHHH
LENFWEKIKDSQLVVLQNEIPHETNLAVAKFCKENAIKVLYNPAPARKTDLEMIEFVDYI
HHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHC
TPNEHECKELFPNEFLEEILAKYANRLIVTLGSEGVIFHDGNEVQKIPAIKAKVVDTTGA
CCCCHHHHHHCHHHHHHHHHHHHHCEEEEEECCCEEEEECCCCCHHCCCEEEEEEECCCC
GDTFNGAFAFGLTENLSIADSIQLAVVASHLSIHKFGAQGGIPSLAEVEDKLKELNLNFY
CCCCCCEEEECCCCCCCHHHHHEEEEHHHHHHHEEECCCCCCCCHHHHHHHHHHCCCCEE
KEKKGL
HHCCCC
>Mature Secondary Structure 
TKVSVVGSISMDLVTSTKRVPQAGETVFGENFAMVPGGKGANQAVAFARLAPRDVNMIG
CEEEEEECCHHHHHHHHHCCCCCCCEEECCCEEECCCCCCCCHHHHHHHCCCCCCEEEE
AVGNDAFGETILKNFKENAVLFDDVGTVPQTTGIAQITLFDDDNRIIIIPGANNEVLPDY
ECCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCHHH
LENFWEKIKDSQLVVLQNEIPHETNLAVAKFCKENAIKVLYNPAPARKTDLEMIEFVDYI
HHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHC
TPNEHECKELFPNEFLEEILAKYANRLIVTLGSEGVIFHDGNEVQKIPAIKAKVVDTTGA
CCCCHHHHHHCHHHHHHHHHHHHHCEEEEEECCCEEEEECCCCCHHCCCEEEEEEECCCC
GDTFNGAFAFGLTENLSIADSIQLAVVASHLSIHKFGAQGGIPSLAEVEDKLKELNLNFY
CCCCCCEEEECCCCCCCHHHHHEEEEHHHHHHHEEECCCCCCCCHHHHHHHHHHCCCCEE
KEKKGL
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]