Click here to switch to the map view.

The map label for this gene is holA [H]

Identifier: 125623622

GI number: 125623622

Start: 757470

End: 758474

Strand: Direct

Name: holA [H]

Synonym: llmg_0768

Alternate gene names: 125623622

Gene position: 757470-758474 (Clockwise)

Preceding gene: 125623621

Following gene: 125623623

Centisome position: 29.95

GC content: 33.23

Gene sequence:

>1005_bases
ATGACTGTATTTGATGAATTTAACGAAGTCAAAAGAAAAGGGCTCCCTCAAATTTTAGTAATTTTTGGTGAGTCAAAAGA
AATGGTTCAAGAATTAAAAAGCCAGTTATTGACTTTTGTAAATTTTGAACCGACAGATTTAAGTCAATCCTACTATGACT
TAACGCCCAATAATAGCGATTTAGCCTTGGAAGACTTGGAATCCCTTCCCTTCTTTTCTGATTCTCGTCTAGTTATTTTG
GAAAACTTGGTCAATTTAACAACGGCTAAAAAAACTATTTTAGATGAAAAACAGCTTAAGCGTTTTGAAAATTTTTTAGA
TAATCCTTCGGAAACCACCCAGCTTGTGTTGGTACTCTATGGGAAATTGGACAGTCGCCTAAAAGTTGTCAAAAAATTAA
AAGCCAAAGCAACTTTACTTGAAGCACAGGAATTAAAAACACAAGAACTCATTCAATATTTTAGTCATGAAACTTCACTG
CCACGGCCTGTATTAAGTCTAATTGCGGCCAAATCTAATGACAGTTTTTCAGTAGTGAAGCAAAATATTGATTTAGTTCA
AACTTATGCTTTAGGGCGTGAAGTCACGGTAGATGATGTAGAAAAAGTAGTTCCAAAATCACTACAAGATAATATCTTTG
CCTTGACTGACTTAATTTTTAAAGGAAAAATTGATGAAGCGCGTGATTTAGTGCATGATTTAACTTTACAAGGAGAAGAT
TTAATTAAAATTTTAGCGATTTTGACTAATTCTTATCGATTGTATTTGCAAGTCAAACTTTTTCAAGAAAAGGGTTGGCA
AGAAAATCAACAGGTTTCATATCTGAAGATGCACCCATATCCAGTGAAATTGGCTAATCAATTGGTCCGAAGATTGCAAG
TGAGTTCTTTAAAAAAAGGACTTGCTGATTTAATTCAACTCGATTTTGCGATAAAAACGAGTGCAGCTGAAAAAGCTTAT
CTTTTTGATATCCTATTAATCAAGTTGACCTTGAAAAAAAACTGA

Upstream 100 bases:

>100_bases
TTTGCTAAGCTATTTAAGTTTGGCTGCATAGGTTTTGCTTTGCTTATTCTAGTGATAATTTTAGTGGGACTTGCTTTAAT
AATGTTGTTGAGGAATTAAT

Downstream 100 bases:

>100_bases
AAATCTGTTATCATAAATAATGGACATTTTATAATGATGATGATGAAGAGGTAAAAATGCCGACATTTAAATTTACGCCT
AAAGATATCTATGAAGCAGA

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTVFDEFNEVKRKGLPQILVIFGESKEMVQELKSQLLTFVNFEPTDLSQSYYDLTPNNSDLALEDLESLPFFSDSRLVIL
ENLVNLTTAKKTILDEKQLKRFENFLDNPSETTQLVLVLYGKLDSRLKVVKKLKAKATLLEAQELKTQELIQYFSHETSL
PRPVLSLIAAKSNDSFSVVKQNIDLVQTYALGREVTVDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGED
LIKILAILTNSYRLYLQVKLFQEKGWQENQQVSYLKMHPYPVKLANQLVRRLQVSSLKKGLADLIQLDFAIKTSAAEKAY
LFDILLIKLTLKKN

Sequences:

>Translated_334_residues
MTVFDEFNEVKRKGLPQILVIFGESKEMVQELKSQLLTFVNFEPTDLSQSYYDLTPNNSDLALEDLESLPFFSDSRLVIL
ENLVNLTTAKKTILDEKQLKRFENFLDNPSETTQLVLVLYGKLDSRLKVVKKLKAKATLLEAQELKTQELIQYFSHETSL
PRPVLSLIAAKSNDSFSVVKQNIDLVQTYALGREVTVDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGED
LIKILAILTNSYRLYLQVKLFQEKGWQENQQVSYLKMHPYPVKLANQLVRRLQVSSLKKGLADLIQLDFAIKTSAAEKAY
LFDILLIKLTLKKN
>Mature_333_residues
TVFDEFNEVKRKGLPQILVIFGESKEMVQELKSQLLTFVNFEPTDLSQSYYDLTPNNSDLALEDLESLPFFSDSRLVILE
NLVNLTTAKKTILDEKQLKRFENFLDNPSETTQLVLVLYGKLDSRLKVVKKLKAKATLLEAQELKTQELIQYFSHETSLP
RPVLSLIAAKSNDSFSVVKQNIDLVQTYALGREVTVDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGEDL
IKILAILTNSYRLYLQVKLFQEKGWQENQQVSYLKMHPYPVKLANQLVRRLQVSSLKKGLADLIQLDFAIKTSAAEKAYL
FDILLIKLTLKKN

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 38229; Mature: 38098

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFDEFNEVKRKGLPQILVIFGESKEMVQELKSQLLTFVNFEPTDLSQSYYDLTPNNSD
CCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCC
LALEDLESLPFFSDSRLVILENLVNLTTAKKTILDEKQLKRFENFLDNPSETTQLVLVLY
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GKLDSRLKVVKKLKAKATLLEAQELKTQELIQYFSHETSLPRPVLSLIAAKSNDSFSVVK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHH
QNIDLVQTYALGREVTVDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGED
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
LIKILAILTNSYRLYLQVKLFQEKGWQENQQVSYLKMHPYPVKLANQLVRRLQVSSLKKG
HHHHHHHHHCCEEEEEEEEEEHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LADLIQLDFAIKTSAAEKAYLFDILLIKLTLKKN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCC
>Mature Secondary Structure 
TVFDEFNEVKRKGLPQILVIFGESKEMVQELKSQLLTFVNFEPTDLSQSYYDLTPNNSD
CCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCC
LALEDLESLPFFSDSRLVILENLVNLTTAKKTILDEKQLKRFENFLDNPSETTQLVLVLY
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GKLDSRLKVVKKLKAKATLLEAQELKTQELIQYFSHETSLPRPVLSLIAAKSNDSFSVVK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHH
QNIDLVQTYALGREVTVDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGED
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
LIKILAILTNSYRLYLQVKLFQEKGWQENQQVSYLKMHPYPVKLANQLVRRLQVSSLKKG
HHHHHHHHHCCEEEEEEEEEEHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LADLIQLDFAIKTSAAEKAYLFDILLIKLTLKKN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]